Tracking Subtle Stereotypes of Children with Trisomy 21: From Facial-Feature-Based to Implicit Stereotyping

Background: Stigmatization is one of the greatest obstacles to the successful integration of people with Trisomy 21 (T21 or Down syndrome), the most frequent genetic disorder associated with intellectual disability. Research on attitudes and stereotypes toward these people still focuses on explicit measures subjected to social-desirability biases, and neglects how variability in facial stigmata influences attitudes and stereotyping. Methodology/Principal Findings: The participants were 165 adults including 55 young adult students, 55 non-student adults, and 55 professional caregivers working with intellectually disabled persons. They were faced with implicit association tests (IAT), a well-known technique whereby response latency is used to capture the relative strength with which some groups of people—here photographed faces of typically developing children and children with T21—are automatically (without conscious awareness) associated with positive versus negative attributes in memory. Each participant also rated the same photographed faces (consciously accessible evaluations). We provide the first evidence that the positive bias typically found in explicit judgments of children with T21 is smaller for those whose facial features are highly characteristic of this disorder, compared to their counterparts with less distinctive features and to typically developing children. We also show that this bias can coexist with negative evaluations at the implicit level (with large effect sizes), even among professional caregivers

A Metabolomic Approach to the Study of Wine Micro-Oxygenation

Wine micro-oxygenation is a globally used treatment and its effects were studied here by analysing by untargeted LC-MS the wine metabolomic fingerprint. Eight different procedural variations, marked by the addition of oxygen (four levels) and iron (two levels) were applied to Sangiovese wine, before and after malolactic fermentation

Diagnostic yield of next-generation sequencing in very early-onset inflammatory bowel diseases: a multicenter study (vol 12, pg 1104, 2021)

Transplantation and immunomodulatio

Regulation of LFA-1-mediated T cell adhesion by CD4

Contains fulltext : 27189___.PDF (publisher's version ) (Open Access

Homogeneity-Related Problems in Solution Derived Powders

International audienc

PREPARATION AND CHARACTERIZATION OF Ge-Si ALLOYS CARRIED OUT BY MOCVD

L'élaboration d'alliages Si-Ge par dépôt chimique en phase vapeur a été entreprise à partir de deux composés organométalliques de formule H3Si-(CH2)2-GeH3 et H3Si-(CH2)3-GeH3. Le comportement thermique de ces composés est étudié par des analyses de la phase gazeuse de décomposition et du matériau solide. Les couches obtenues sont composées de silicium, de germanium e t ne contiennent pas de carbone. En fonction de ces résultats et de caractérisations physico-chimiques des précurseurs et du matériau une discussion nous amène à proposer une structure du matériau.The preparation of Ge-Si alloys by chemical vapour deposition has been undertaken using two organometallic compounds, H3Si-(CH2)2-GeH3 and H3Si -(CH2)3-GeH3. Their thermal behaviour was investigated by analysis of the gaseous products of decomposition and of the solid material. The thin coatings are composed of silicon , germanium and do not contain carbon. According to these results and physico-chemical characterizations of the precursors and the products, we are lead to propose a structure for the solid material