31,259 research outputs found
Evolutionary approach to overcome initialization parameters in classification problems
Proceeding of: 7th International Work-Conference on Artificial and Natural Neural Networks, IWANN 2003 Maó, Menorca, Spain, June 3–6, 2003.The design of nearest neighbour classifiers is very dependent from some crucial parameters involved in learning, like the number of prototypes to use, the initial localization of these prototypes, and a smoothing parameter. These parameters have to be found by a trial and error process or by some automatic methods. In this work, an evolutionary approach based on Nearest Neighbour Classifier (ENNC), is described. Main property of this algorithm is that it does not require any of the above mentioned parameters. The algorithm is based on the evolution of a set of prototypes that can execute several operators in order to increase their quality in a local sense, and emerging a high classification accuracy for the whole classifier
Noise from spatial heterogeneity changes signal amplification magnitude and increases the variability in dose responses
In most molecular level simulations, spatial heterogeneity is neglected by the well-mixed condition assumption. However, the signals of biomolecular
networks are affected from both time and space, which are responsible for diverse physiological responses. To account the spatial heterogeneity in the
kinetic model, we consider multiple subvolumes of a reaction, introduce parameters representing transfer of ligands between the volumes, and reduce
this to an error-term representing the difference between the well-mixed condition and the actual spatial factors. The error-term approach allows
modelling of varying spatial heterogeneity without increasing computational burden exponentially.
The effect of varying this term, d, between 0 (well-mixed) and 1 (no mixing) and of adding noise to the kinetic constants was then investigated and
correlated with knowledge of the behaviour of real systems and situations where network models are inadequate. The spatial distribution effects on the
epidermal growth factor receptor (EGFR) in human mammary epithelial tissue, which is involved in proliferation and tumorigenesis, are studied by
introducing noisy kinetic constants.
The steady-state of the dose response in the
EGFR is strongly affected by spatial
fluctuations. The ligand-bound receptor is
reduced up to 50% from the response
without spatial fluctuations and the variance
of the steady-state is increased at least 2-fold
from the one for no spatial fluctuations. On
the other hand, dynamic properties such as
the rising time and overshoot are less
sensitive to spatial noise
Measurements in liquid fuel sprays
A ground test facility is being established at NASA Lewis Research Center to simulate the environmental and flight conditions needed to study adverse weather effects. One of the most important components is the water spray system which consists of many nozzles fitted on spray bars. Water is injected through air-assisted atomizers to generate uniform size drops to simulate icing in clouds. The primary objective is to provide experimental data on drop size distribution over a wide range of operating conditions. Correlation equations for mean drop size and initial injection parameters are being determined to assist in the design and modification of the Altitude Wind Tunnel. Special emphasis is being placed on the study of the aerodynamic structure of the air-assisted atomizer sprays. Detailed measurements of the variation of drop size distribution and velocity as a function of time and space are being made. Accurate initial and boundary conditions are being provided for computer model evaluation
Site evaluation for laser satellite-tracking stations
Twenty-six locations for potential laser satellite-tracking stations, four of them actually already occupied in this role, are reviewed in terms of their known local and regional geology and geophysics. The sites are also considered briefly in terms of weather and operational factors. Fifteen of the sites qualify as suitable for a stable station whose motions are likely to reflect only gross plate motion. The others, including two of the present laser station sites (Arequipa and Athens), fail to qualify unless extra monitoring schemes can be included, such as precise geodetic surveying of ground deformation
The absolute radiometric calibration of the advanced very high resolution radiometer
The early results of an absolute radiometric calibration of the NOAA-9 AVHRR sensor indicate significant degradations in the response of bands 1 and 2 compared to prelaunch values. The results are currently in the process of being verified and it may be that refinements of the methodology will be in order as additional data sets are analyzed. The LANDSAT TM calibration used in this approach is known to be very precise and the Herman radiative transfer code, supplemented by the 5-S code for gaseous transmission, is reliable as well. The extent to which other steps in the analysis procedure give rise to uncertainties in the results is currently under investigation. Particular attention is being given to the geometric matching of the AVHRR and TM imagery, as well as to the spectral redistribution procedure. By taking advantage of a reasonably precise calibration of TM imagery acquired on the same day as the AVHRR data at White Sands, a promising approach to the in-orbit calibration of AVHRR sensors is being developed. Current efforts involve primarily the examination of additional test cases and the investigation of possible simplifications in the procedure through judicious use of atmospheric models
A Burgess-like subconvex bound for twisted L-functions
Let g be a cuspidal newform (holomorphic or Maass) of arbitrary level and nebentypus, X a primitive character of conductor q, and s a point on the critical line Rs = 1/2. It is proved that
L(g circle times chi, s) 0
is arbitrary and theta = 7/64 is the current known approximation towards the RamannJan-Petersson conjecture (which would allow theta = 0); moreover, the dependence on s and all the parameters of g is polynomial. This result is an analog of Burgess' classical subconvex bound for Dirichlet L-functions. In Appendix 2 the above result is combined with a theorem of Waldspurger and the adelic calculations of Baruch-Mao to yield an improved uniform upper bound for the Fourier coefficients of holomorphic half-integral weight cusp forms
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