21,629 research outputs found
A new code for Fourier-Legendre analysis of large datasets: first results and a comparison with ring-diagram analysis
Fourier-Legendre decomposition (FLD) of solar Doppler imaging data is a
promising method to estimate the sub-surface solar meridional flow. FLD is
sensible to low-degree oscillation modes and thus has the potential to probe
the deep meridional flow. We present a newly developed code to be used for
large scale FLD analysis of helioseismic data as provided by the Global
Oscillation Network Group (GONG), the Michelson Doppler Imager (MDI)
instrument, and the upcoming Helioseismic and Magnetic Imager (HMI) instrument.
First results obtained with the new code are qualitatively comparable to those
obtained from ring-diagram analyis of the same time series.Comment: 4 pages, 2 figures, 4th HELAS International Conference "Seismological
Challenges for Stellar Structure", 1-5 February 2010, Arrecife, Lanzarote
(Canary Islands
Repulsive Casimir Pistons
Casimir pistons are models in which finite Casimir forces can be calculated
without any suspect renormalizations. It has been suggested that such forces
are always attractive. We present three scenarios in which that is not true.
Two of these depend on mixing two types of boundary conditions. The other,
however, is a simple type of quantum graph in which the sign of the force
depends upon the number of edges.Comment: 4 pages, 2 figures; RevTeX. Minor additions and correction
Polymeric forms of carbon in dense lithium carbide
The immense interest in carbon nanomaterials continues to stimulate intense
research activities aimed to realize carbon nanowires, since linear chains of
carbon atoms are expected to display novel and technologically relevant
optical, electrical and mechanical properties. Although various allotropes of
carbon (e.g., diamond, nanotubes, graphene, etc.) are among the best known
materials, it remains challenging to stabilize carbon in the one-dimensional
form because of the difficulty to suitably saturate the dangling bonds of
carbon. Here, we show through first-principles calculations that ordered
polymeric carbon chains can be stabilized in solid LiC under moderate
pressure. This pressure-induced phase (above 5 GPa) consists of parallel arrays
of twofold zigzag carbon chains embedded in lithium cages, which display a
metallic character due to the formation of partially occupied carbon lone-pair
states in \emph{sp}-like hybrids. It is found that this phase remains the
most favorable one in a wide range of pressure. At extreme pressure (larger the
215 GPa) a structural and electronic phase transition towards an insulating
single-bonded threefold-coordinated carbon network is predicted.Comment: 10 pages, 6 figure
Deficiency of RgpG causes major defects in cell division and biofilm formation, and deficiency of LytR-CpsAPsr family proteins leads to accumulation of cell wall antigens in culture medium by Streptococcus mutans
ABSTRACT
Streptococcus mutans
is known to possess rhamnose-glucose polysaccharide (RGP), a major cell wall antigen.
S. mutans
strains deficient in
rgpG
, encoding the first enzyme of the RGP biosynthesis pathway, were constructed by allelic exchange. The
rgpG
deficiency had no effect on growth rate but caused major defects in cell division and altered cell morphology. Unlike the coccoid wild type, the
rgpG
mutant existed primarily in chains of swollen, “squarish” dividing cells. Deficiency of
rgpG
also causes significant reduction in biofilm formation (
P
< 0.01). Double and triple mutants with deficiency in
brpA
and/or
psr
, genes coding for the LytR-CpsA-Psr family proteins BrpA and Psr, which were previously shown to play important roles in cell envelope biogenesis, were constructed using the
rgpG
mutant. There were no major differences in growth rates between the wild-type strain and the
rgpG brpA
and
rgpG psr
double mutants, but the growth rate of the
rgpG brpA psr
triple mutant was reduced drastically (
P
< 0.001). Under transmission electron microscopy, both double mutants resembled the
rgpG
mutant, while the triple mutant existed as giant cells with multiple asymmetric septa. When analyzed by immunoblotting, the
rgpG
mutant displayed major reductions in cell wall antigens compared to the wild type, while little or no signal was detected with the double and triple mutants and the
brpA
and
psr
single mutants. These results suggest that RgpG in
S. mutans
plays a critical role in cell division and biofilm formation and that BrpA and Psr may be responsible for attachment of cell wall antigens to the cell envelope.
IMPORTANCE
Streptococcus mutans
, a major etiological agent of human dental caries, produces rhamnose-glucose polysaccharide (RGP) as the major cell wall antigen. This study provides direct evidence that deficiency of RgpG, the first enzyme of the RGP biosynthesis pathway, caused major defects in cell division and morphology and reduced biofilm formation by
S. mutans
, indicative of a significant role of RGP in cell division and biofilm formation in
S. mutans
. These results are novel not only in
S. mutans
, but also other streptococci that produce RGP. This study also shows that the LytR-CpsA-Psr family proteins BrpA and Psr in
S. mutans
are involved in attachment of RGP and probably other cell wall glycopolymers to the peptidoglycan. In addition, the results also suggest that BrpA and Psr may play a direct role in cell division and biofilm formation in
S. mutans
. This study reveals new potential targets to develop anticaries therapeutics.
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Manipulation Strategies for the Rank Maximal Matching Problem
We consider manipulation strategies for the rank-maximal matching problem. In
the rank-maximal matching problem we are given a bipartite graph such that denotes a set of applicants and a set of posts. Each
applicant has a preference list over the set of his neighbours in
, possibly involving ties. Preference lists are represented by ranks on the
edges - an edge has rank , denoted as , if post
belongs to one of 's -th choices. A rank-maximal matching is one in which
the maximum number of applicants is matched to their rank one posts and subject
to this condition, the maximum number of applicants is matched to their rank
two posts, and so on. A rank-maximal matching can be computed in time, where denotes the number of applicants, the
number of edges and the maximum rank of an edge in an optimal solution.
A central authority matches applicants to posts. It does so using one of the
rank-maximal matchings. Since there may be more than one rank- maximal matching
of , we assume that the central authority chooses any one of them randomly.
Let be a manipulative applicant, who knows the preference lists of all
the other applicants and wants to falsify his preference list so that he has a
chance of getting better posts than if he were truthful. In the first problem
addressed in this paper the manipulative applicant wants to ensure that
he is never matched to any post worse than the most preferred among those of
rank greater than one and obtainable when he is truthful. In the second problem
the manipulator wants to construct such a preference list that the worst post
he can become matched to by the central authority is best possible or in other
words, wants to minimize the maximal rank of a post he can become matched
to
Near-infrared images of star forming regions containing masers. Las Campanas observations of 31 southern sources
We present sensitive high resolution near infrared (NIR) broad band (J, H, and K) observations of a sample of 31 Star Forming Regions (SFRs) which contain H_2O and OH maser sources. The observations are aimed at the detection and characterization of Young Stellar Objects (YSOs) which may be the source of excitation of the maser emission. In spite of the large number of sources detected in the regions, using positional coincidence and NIR colours we are able to reliably identify K-band sources related to the masing gas in a large fraction of the observed regions. The NIR infrared sources selected from close positional coincidence with the maser show strong NIR excesses and most probably represent the YSOs still embedded in their parental cocoon where the maser emission occurs
Group Strategyproof Pareto-Stable Marriage with Indifferences via the Generalized Assignment Game
We study the variant of the stable marriage problem in which the preferences
of the agents are allowed to include indifferences. We present a mechanism for
producing Pareto-stable matchings in stable marriage markets with indifferences
that is group strategyproof for one side of the market. Our key technique
involves modeling the stable marriage market as a generalized assignment game.
We also show that our mechanism can be implemented efficiently. These results
can be extended to the college admissions problem with indifferences
A 31T split-pair pulsed magnet for single crystal x-ray diffraction at low temperature
We have developed a pulsed magnet system with panoramic access for
synchrotron x-ray diffraction in magnetic fields up to 31T and at low
temperature down to 1.5 K. The apparatus consists of a split-pair magnet, a
liquid nitrogen bath to cool the pulsed coil, and a helium cryostat allowing
sample temperatures from 1.5 up to 250 K. Using a 1.15MJ mobile generator,
magnetic field pulses of 60 ms length were generated in the magnet, with a rise
time of 16.5 ms and a repetition rate of 2 pulses/hour at 31 T. The setup was
validated for single crystal diffraction on the ESRF beamline ID06
Bethe Ansatz solution of a decagonal rectangle triangle random tiling
A random tiling of rectangles and triangles displaying a decagonal phase is
solved by Bethe Ansatz. Analogously to the solutions of the dodecagonal square
triangle and the octagonal rectangle triangle tiling an exact expression for
the maximum of the entropy is found.Comment: 17 pages, 4 figures, some remarks added and typos correcte
Atomic Bose and Anderson glasses in optical lattices
An ultra cold atomic Bose gas in an optical lattice is shown to provide an
ideal system for the controlled analysis of disordered Bose lattice gases. This
goal may be easily achieved under the current experimental conditions, by
introducing a pseudo-random potential created by a second additional lattice
or, alternatively, by placing a speckle pattern on the main lattice. We show
that for a non commensurable filling factor, in the strong interaction limit, a
controlled growing of the disorder drives a dynamical transition from
superfluid to Bose-glass phase. Similarly, in the weak interaction limit, a
dynamical transition from superfluid to Anderson-glass phase may be observed.
In both regimes, we show that even very low-intensity disorder-inducing lasers
cause large modifications of the superfluid fraction of the system.Comment: 4 pages, 3 figures. Minor changes. To appear in Phys. Rev. Lett.
(2003
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