4,441 research outputs found

    Directional asymmetries reveal a universal bias in adult vowel perception

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    published online 21 April 2017Research on cross-language vowel perception in both infants and adults has shown that for many vowel contrasts, discrimination is easier when the same pair of vowels is presented in one direction compared to the reverse direction. According to one account, these directional asymmetries reflect a universal bias favoring “focal” vowels (i.e., vowels whose adjacent formants are close in frequency, which concentrates acoustic energy into a narrower spectral region). An alternative, but not mutually exclusive, account is that such effects reflect an experience-dependent bias favoring prototypical instances of native-language vowel categories. To disentangle the effects of focalization and prototypicality, the authors first identified a certain location in phonetic space where vowels were consistently categorized as /u/ by both Canadian-English and Canadian-French listeners, but that nevertheless varied in their stimulus goodness (i.e., the best Canadian-French /u/ exemplars were more focal compared to the best Canadian-English /u/ exemplars). In subsequent AX discrimination tests, both Canadian-English and Canadian-French listeners performed better at discriminating changes from less to more focal /u/’s compared to the reverse, regardless of variation in prototypicality. These findings demonstrate a universal bias favoring vowels with greater formant convergence that operates independently of biases related to language-specific prototype categorization.This research was supported by NSERC Discovery Grant No. 105397 to L.P. and NSERC Discovery Grant No. 312395 to L.M

    NS1 Specific CD8(+) T-Cells with Effector Function and TRBV11 Dominance in a Patient with Parvovirus B19 Associated Inflammatory Cardiomyopathy

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    Background: Parvovirus B19 (B19V) is the most commonly detected virus in endomyocardial biopsies (EMBs) from patients with inflammatory cardiomyopathy (DCMi). Despite the importance of T-cells in antiviral defense, little is known about the role of B19V specific T-cells in this entity. Methodology and Principal Findings: An exceptionally high B19V viral load in EMBs (115,091 viral copies/mg nucleic acids), peripheral blood mononuclear cells (PBMCs) and serum was measured in a DCMi patient at initial presentation, suggesting B19V viremia. The B19V viral load in EMBs had decreased substantially 6 and 12 months afterwards, and was not traceable in PBMCs and the serum at these times. Using pools of overlapping peptides spanning the whole B19V proteome, strong CD8(+) T-cell responses were elicited to the 10-amico-acid peptides SALKLAIYKA (19.7% of all CD8(+) cells) and QSALKLAIYK (10%) and additional weaker responses to GLCPHCINVG (0.71%) and LLHTDFEQVM (0.06%). Real-time RT-PCR of IFN gamma secretion-assay-enriched T-cells responding to the peptides, SALKLAIYKA and GLCPHCINVG, revealed a disproportionately high T-cell receptor Vbeta (TRBV) 11 expression in this population. Furthermore, dominant expression of type-1 (IFN gamma, IL2, IL27 and Tbet) and of cytotoxic T-cell markers (Perforin and Granzyme B) was found, whereas gene expression indicating type-2 (IL4, GATA3) and regulatory T-cells (FoxP3) was low. Conclusions: Our results indicate that B19V Ag-specific CD8(+) T-cells with effector function are involved in B19V associated DCMi. In particular, a dominant role of TRBV11 and type-1/CTL effector cells in the T-cell mediated antiviral immune response is suggested. The persistence of B19V in the endomyocardium is a likely antigen source for the maintenance of CD8(+) T-cell responses to the identified epitopes

    An efficient Fredholm method for calculation of highly excited states of billiards

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    A numerically efficient Fredholm formulation of the billiard problem is presented. The standard solution in the framework of the boundary integral method in terms of a search for roots of a secular determinant is reviewed first. We next reformulate the singularity condition in terms of a flow in the space of an auxiliary one-parameter family of eigenproblems and argue that the eigenvalues and eigenfunctions are analytic functions within a certain domain. Based on this analytic behavior we present a numerical algorithm to compute a range of billiard eigenvalues and associated eigenvectors by only two diagonalizations.Comment: 15 pages, 10 figures; included systematic study of accuracy with 2 new figures, movie to Fig. 4, http://www.quantumchaos.de/Media/0703030media.av

    Willing and able: action-state orientation and the relation between procedural justice and employee cooperation

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    Existing justice theory explains why fair procedures motivate employees to adopt cooperative goals, but it fails to explain how employees strive towards these goals. We study self-regulatory abilities that underlie goal striving; abilities that should thus affect employees’ display of cooperative behavior in response to procedural justice. Building on action control theory, we argue that employees who display effective self-regulatory strategies (action oriented employees) display relatively strong cooperative behavioral responses to fair procedures. A multisource field study and a laboratory experiment support this prediction. A subsequent experiment addresses the process underlying this effect by explicitly showing that action orientation facilitates attainment of the cooperative goals that people adopt in response to fair procedures, thus facilitating the display of actual cooperative behavior. This goal striving approach better integrates research on the relationship between procedural justice and employee cooperation in the self-regulation and the work motivation literature. It also offers organizations a new perspective on making procedural justice effective in stimulating employee cooperation by suggesting factors that help employees reach their adopted goals

    Mobility Edge in Aperiodic Kronig-Penney Potentials with Correlated Disorder: Perturbative Approach

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    It is shown that a non-periodic Kronig-Penney model exhibits mobility edges if the positions of the scatterers are correlated at long distances. An analytical expression for the energy-dependent localization length is derived for weak disorder in terms of the real-space correlators defining the structural disorder in these systems. We also present an algorithm to construct a non-periodic but correlated sequence exhibiting desired mobility edges. This result could be used to construct window filters in electronic, acoustic, or photonic non-periodic structures.Comment: RevTex, 4 pages including 2 Postscript figure

    Playing relativistic billiards beyond graphene

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    The possibility of using hexagonal structures in general and graphene in particular to emulate the Dirac equation is the basis of our considerations. We show that Dirac oscillators with or without restmass can be emulated by distorting a tight binding model on a hexagonal structure. In a quest to make a toy model for such relativistic equations we first show that a hexagonal lattice of attractive potential wells would be a good candidate. First we consider the corresponding one-dimensional model giving rise to a one-dimensional Dirac oscillator, and then construct explicitly the deformations needed in the two-dimensional case. Finally we discuss, how such a model can be implemented as an electromagnetic billiard using arrays of dielectric resonators between two conducting plates that ensure evanescent modes outside the resonators for transversal electric modes, and describe an appropriate experimental setup.Comment: 23 pages, 8 figures. Submitted to NJ

    Magnon delocalization in ferromagnetic chains with long-range correlated disorder

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    We study one-magnon excitations in a random ferromagnetic Heisenberg chain with long-range correlations in the coupling constant distribution. By employing an exact diagonalization procedure, we compute the localization length of all one-magnon states within the band of allowed energies EE. The random distribution of coupling constants was assumed to have a power spectrum decaying as S(k)1/kαS(k)\propto 1/k^{\alpha}. We found that for α<1\alpha < 1, one-magnon excitations remain exponentially localized with the localization length ξ\xi diverging as 1/E. For α=1\alpha = 1 a faster divergence of ξ\xi is obtained. For any α>1\alpha > 1, a phase of delocalized magnons emerges at the bottom of the band. We characterize the scaling behavior of the localization length on all regimes and relate it with the scaling properties of the long-range correlated exchange coupling distribution.Comment: 7 Pages, 5 figures, to appear in Phys. Rev.

    Size and shape constancy in consumer virtual reality

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    With the increase in popularity of consumer virtual reality headsets, for research and other applications, it is important to understand the accuracy of 3D perception in VR. We investigated the perceptual accuracy of near-field virtual distances using a size and shape constancy task, in two commercially available devices. Participants wore either the HTC Vive or the Oculus Rift and adjusted the size of a virtual stimulus to match the geometric qualities (size and depth) of a physical stimulus they were able to refer to haptically. The judgments participants made allowed for an indirect measure of their perception of the egocentric, virtual distance to the stimuli. The data show under-constancy and are consistent with research from carefully calibrated psychophysical techniques. There was no difference in the degree of constancy found in the two headsets. We conclude that consumer virtual reality headsets provide a sufficiently high degree of accuracy in distance perception, to allow them to be used confidently in future experimental vision science, and other research applications in psychology

    Statistics of Resonances and Delay Times in Random Media: Beyond Random Matrix Theory

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    We review recent developments on quantum scattering from mesoscopic systems. Various spatial geometries whose closed analogs shows diffusive, localized or critical behavior are considered. These are features that cannot be described by the universal Random Matrix Theory results. Instead one has to go beyond this approximation and incorporate them in a non-perturbative way. Here, we pay particular emphasis to the traces of these non-universal characteristics, in the distribution of the Wigner delay times and resonance widths. The former quantity captures time dependent aspects of quantum scattering while the latter is associated with the poles of the scattering matrix.Comment: 30 pages, 15 figures (submitted to Journal of Phys. A: Math. and General, special issue on "Aspects of Quantum Chaotic Scattering"
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