672 research outputs found
Near mean-field behavior in the generalized Burridge-Knopoff earthquake model with variable range stress transfer
Simple models of earthquake faults are important for understanding the
mechanisms for their observed behavior in nature, such as Gutenberg-Richter
scaling. Because of the importance of long-range interactions in an elastic
medium, we generalize the Burridge-Knopoff slider-block model to include
variable range stress transfer. We find that the Burridge-Knopoff model with
long-range stress transfer exhibits qualitatively different behavior than the
corresponding long-range cellular automata models and the usual
Burridge-Knopoff model with nearest-neighbor stress transfer, depending on how
quickly the friction force weakens with increasing velocity. Extensive
simulations of quasiperiodic characteristic events, mode-switching phenomena,
ergodicity, and waiting-time distributions are also discussed. Our results are
consistent with the existence of a mean-field critical point and have important
implications for our understanding of earthquakes and other driven dissipative
systems.Comment: 24 pages 12 figures, revised version for Phys. Rev.
An in situ assessment of local adaptation in a calcifying polychaete from a shallow CO 2 vent system
Ocean acidification (OA) is likely to exert selective pressure on natural populations. Our ability to predict which marine species will adapt to OA and what underlies this adaptive potential is of high conservation and resource management priority. Using a naturally low-pH vent site in the Mediterranean Sea (Castello Aragonese, Ischia) mirroring projected future OA conditions, we carried out a reciprocal transplant experiment to investigate the relative importance of phenotypic plasticity and local adaptation in two populations of the sessile, calcifying polychaete Simplaria sp. (Annelida, Serpulidae, Spirorbinae): one residing in low pH and the other from a nearby ambient (i.e. high) pH site. We measured a suite of fitness-related traits (i.e. survival, reproductive output, maturation, population growth) and tube growth rates in laboratory-bred F2 generation individuals from both populations reciprocally transplanted back into both ambient and low-pH in situ habitats. Both populations showed lower expression in all traits, but increased tube growth rates, when exposed to low-pH compared with high-pH conditions, regardless of their site of origin suggesting that local adaptation to low-pH conditions has not occurred. We also found comparable levels of plasticity in the two populations investigated, suggesting no influence of long-term exposure to low pH on the ability of populations to adjust their phenotype. Despite high variation in trait values among sites and the relatively extreme conditions at the low pH site (pH < 7.36), response trends were consistent across traits. Hence, our data suggest that, for Simplaria and possibly other calcifiers, neither local adaptations nor sufficient phenotypic plasticity levels appear to suffice in order to compensate for the negative impacts of OA on long-term survival. Our work also emphasizes the utility of field experiments in natural environments subjected to high level of pCO2 for elucidating the potential for adaptation to future scenarios of OA
Gutenberg Richter and Characteristic Earthquake Behavior in Simple Mean-Field Models of Heterogeneous Faults
The statistics of earthquakes in a heterogeneous fault zone is studied
analytically and numerically in the mean field version of a model for a
segmented fault system in a three-dimensional elastic solid. The studies focus
on the interplay between the roles of disorder, dynamical effects, and driving
mechanisms. A two-parameter phase diagram is found, spanned by the amplitude of
dynamical weakening (or ``overshoot'') effects (epsilon) and the normal
distance (L) of the driving forces from the fault. In general, small epsilon
and small L are found to produce Gutenberg-Richter type power law statistics
with an exponential cutoff, while large epsilon and large L lead to a
distribution of small events combined with characteristic system-size events.
In a certain parameter regime the behavior is bistable, with transitions back
and forth from one phase to the other on time scales determined by the fault
size and other model parameters. The implications for realistic earthquake
statistics are discussed.Comment: 21 pages, RevTex, 6 figures (ps, eps
Avalanches in Breakdown and Fracture Processes
We investigate the breakdown of disordered networks under the action of an
increasing external---mechanical or electrical---force. We perform a mean-field
analysis and estimate scaling exponents for the approach to the instability. By
simulating two-dimensional models of electric breakdown and fracture we observe
that the breakdown is preceded by avalanche events. The avalanches can be
described by scaling laws, and the estimated values of the exponents are
consistent with those found in mean-field theory. The breakdown point is
characterized by a discontinuity in the macroscopic properties of the material,
such as conductivity or elasticity, indicative of a first order transition. The
scaling laws suggest an analogy with the behavior expected in spinodal
nucleation.Comment: 15 pages, 12 figures, submitted to Phys. Rev. E, corrected typo in
authors name, no changes to the pape
A tri-dimensional approach for auditing brand loyalty
Over the past twenty years brand loyalty has been an important topic for both marketing practitioners and academics. While practitioners have produced proprietary brand loyalty audit models, there has been little academic research to make transparent the methodology that underpins these audits and to enable practitioners to understand, develop and conduct their own audits. In this paper, we propose a framework for a brand loyalty audit that uses a tri-dimensional approach to brand loyalty, which includes behavioural loyalty and the two components of attitudinal loyalty: emotional and cognitive loyalty. In allowing for different levels and intensity of brand loyalty, this tri-dimensional approach is important from a managerial perspective. It means that loyalty strategies that arise from a brand audit can be made more effective by targeting the market segments that demonstrate the most appropriate combination of brand loyalty components. We propose a matrix with three dimensions (emotional, cognitive and behavioural loyalty) and two levels (high and low loyalty) to facilitate a brand loyalty audit. To demonstrate this matrix, we use the example of financial services, in particular a rewards-based credit card
A comparison of life-history traits in calcifying Spirorbinae polychaetes living along natural pH gradients
© Inter-Research 2018. Low-pH vent systems are ideal natural laboratories to study the consequences of long-term low-pH exposure on marine species and thus identify life-history traits associated with low-pH tolerance. This knowledge can help to inform predictions on which types of species may be less vulnerable in future ocean acidification (OA) scenarios. Accordingly, we investigated how traits of calcifying polychaete species (Serpulidae, Spirorbinae) varied with pH using a functional trait analysis at 2 natural pH gradients around the Castello Aragonese islet off Ischia, Italy. We first observed the distribution and abundance patterns of all calcifying polychaete epiphytes in the canopy of Posidonia oceanica seagrass across these gradients. We then used laboratory trials to compare fecundity, settlement success, and juvenile survival in the dominant species from a control (Pileolaria militaris Claparède, 1870) and a low-pH site (Simplaria sp.). We found significantly higher reproductive output, juvenile settlement rates, and juvenile survival in Simplaria sp. individuals from the low-pH site, compared to P. militaris individuals from control pH sites, when observed in their respective in situ pH conditions. Our results suggest that tolerance to low pH may result, in part, from traits associated with successful reproduction and rapid settlement under low-pH conditions. This finding implies that other species with similar life-history traits may respond similarly, and should be targeted for future OA tolerance research
Self-organized criticality and synchronization in a lattice model of integrate-and-fire oscillators
We introduce two coupled map lattice models with nonconservative interactions
and a continuous nonlinear driving. Depending on both the degree of
conservation and the convexity of the driving we find different behaviors,
ranging from self-organized criticality, in the sense that the distribution of
events (avalanches) obeys a power law, to a macroscopic synchronization of the
population of oscillators, with avalanches of the size of the system.Comment: 4 pages, Revtex 3.0, 3 PostScript figures available upon request to
[email protected]
Statistics of Earthquakes in Simple Models of Heterogeneous Faults
Simple models for ruptures along a heterogeneous earthquake fault zone are
studied, focussing on the interplay between the roles of disorder and dynamical
effects. A class of models are found to operate naturally at a critical point
whose properties yield power law scaling of earthquake statistics. Various
dynamical effects can change the behavior to a distribution of small events
combined with characteristic system size events. The studies employ various
analytic methods as well as simulations.Comment: 4 pages, RevTex, 3 figures (eps-files), uses eps
Asthma in Inner-City Children at 5–11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort
Background: Studies suggest that phthalate exposures may adversely affect child respiratory health. Objectives: We evaluated associations between asthma diagnosed in children between 5 and 11 years of age and prenatal exposures to butylbenzyl phthalate (BBzP), di-n-butyl phthalate (DnBP), di(2-ethylhexyl) phthalate (DEHP), and diethyl phthalate (DEP). Methods: Phthalate metabolites were measured in spot urine collected from 300 pregnant inner-city women. Children were examined by an allergist or pulmonologist based on the first parental report of wheeze, other respiratory symptoms, and/or use of asthma rescue/controller medication in the preceding 12 months on repeat follow-up questionnaires. Standardized diagnostic criteria were used to classify these children as either having or not having current asthma at the time of the physician examination. Children without any report of wheeze or the other asthma-like symptoms were classified as nonasthmatics at the time of the last negative questionnaire. Modified Poisson regression analyses were used to estimate relative risks (RR) controlling for specific gravity and potential confounders. Results: Of 300 children, 154 (51%) were examined by a physician because of reports of wheeze, other asthma-like symptoms, and/or medication use; 94 were diagnosed with current asthma and 60 without current asthma. The remaining 146 children were classified as nonasthmatic. Compared with levels in nonasthmatics, prenatal metabolites of BBzP and DnBP were associated with a history of asthma-like symptoms (p 70% higher among children with maternal prenatal BBzP and DnBP metabolite concentrations in the third versus the first tertile. Conclusion: Prenatal exposure to BBzP and DnBP may increase the risk of asthma among inner-city children. However, because this is the first such finding, results require replication. Citation: Whyatt RM, Perzanowski MS, Just AC, Rundle AG, Donohue KM, Calafat AM, Hoepner LA, Perera FP, Miller RL. 2014. Asthma in inner-city children at 5–11 years of age and prenatal exposure to phthalates: the Columbia Center for Children’s Environmental Health Cohort. Environ Health Perspect 122:1141–1146; http://dx.doi.org/10.1289/ehp.130767
Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage.
A defective response to DNA damage is observed in several human autosomal
recessive ataxias with oculomotor apraxia, including ataxia-telangiectasia. We
report that senataxin, defective in ataxia oculomotor apraxia (AOA) type 2, is a
nuclear protein involved in the DNA damage response. AOA2 cells are sensitive to
H2O2, camptothecin, and mitomycin C, but not to ionizing radiation, and
sensitivity was rescued with full-length SETX cDNA. AOA2 cells exhibited
constitutive oxidative DNA damage and enhanced chromosomal instability in
response to H2O2. Rejoining of H2O2-induced DNA double-strand breaks (DSBs) was
significantly reduced in AOA2 cells compared to controls, and there was no
evidence for a defect in DNA single-strand break repair. This defect in DSB
repair was corrected by full-length SETX cDNA. These results provide evidence
that an additional member of the autosomal recessive AOA is also characterized by
a defective response to DNA damage, which may contribute to the neurodegeneration
seen in this syndrome
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