1,233 research outputs found
Stochastic Geometric Coverage Analysis in mmWave Cellular Networks With Realistic Channel and Antenna Radiation Models
Millimeter-wave (mmWave) bands will play an important role in 5G wireless systems. The system performance can be assessed by using models from stochastic geometry that cater for the directivity in the desired signal transmissions as well as the interference, and by calculating the signal-To-interference-plus-noise ratio ( \mathsf {SINR} ) coverage. Nonetheless, the accuracy of the existing coverage expressions derived through stochastic geometry may be questioned, as it is not clear whether they would capture the impact of the detailed mmWave channel and antenna features. In this paper, we propose an \mathsf {SINR} coverage analysis framework that includes realistic channel model and antenna element radiation patterns. We introduce and estimate two parameters, aligned gain and misaligned gain, associated with the desired signal beam and the interfering signal beam, respectively. The distributions of these gains are used to determine the distribution of the \mathsf {SINR} which is compared with the corresponding \mathsf {SINR} coverage, calculated through the system-level simulations. The results show that both aligned and misaligned gains can be modeled as exponential-logarithmically distributed random variables with the highest accuracy, and can further be approximated as exponentially distributed random variables with reasonable accuracy. These approximations can be used as a tool to evaluate the system-level performance of various 5G connectivity scenarios in the mmWave band.</p
The Low Energy Tagger for the KLOE-2 experiment
The KLOE experiment at the upgraded DAFNE e+e- collider in Frascati (KLOE-2)
is going to start a new data taking at the beginning of 2010 with its detector
upgraded with a tagging system for the identification of gamma-gamma
interactions. The tagging stations for low-energy e+e- will consist in two
calorimeters The calorimeter used to detect low-energy e+e- will be placed
between the beam-pipe outer support structure and the inner wall of the KLOE
drift chamber. This calorimeter will be made of LYSO crystals readout by
Silicon Photomultipliers, to achieve an energy resolution better than 8% at 200
MeV.Comment: 4 pages, 5 figures, in the proceedings of "Frontier detectors for
frontier physics", isola d'Elba, Italy, May 200
Measurement of neutron detection efficiency between 22 and 174 MeV using two different kinds of Pb-scintillating fiber sampling calorimeters
We exposed a prototype of the lead-scintillating fiber KLOE calorimeter to
neutron beam of 21, 46 and 174 MeV at The Svedberg Laboratory, Uppsala, to
study its neutron detection efficiency. This has been found larger than what
expected considering the scintillator thickness of the prototype. %To check our
method, we measured also the neutron %detection efficiency of a 5 cm thick
NE110 scintillator. We show preliminary measurement carried out with a
different prototype with a larger lead/fiber ratio, which proves the relevance
of passive material to neutron detection efficiency in this kind of
calorimeters
Thoracic involvement in systemic autoimmune rheumatic diseases: pathogenesis and management.
Thoracic involvement is one of the main determinants of morbidity and mortality in patients with autoimmune rheumatic diseases (ARDs), with different prevalence and manifestations according to the underlying disease. Interstitial lung disease (ILD) is the most common pulmonary complication, particularly in patients with systemic sclerosis (SSc), idiopathic inflammatory myopathies (IIMs) and rheumatoid arthritis (RA). Other thoracic manifestations include pulmonary arterial hypertension (PAH), mostly in patients with SSc, airway disease, mainly in RA, and pleural involvement, which is common in systemic lupus erythematosus and RA, but rare in other ARDs.In this review, we summarize and critically discuss the current knowledge on thoracic involvement in ARDs, with emphasis on disease pathogenesis and management. Immunosuppression is the mainstay of therapy, particularly for ARDs-ILD, but it should be reserved to patients with clinically significant disease or at risk of progressive disease. Therefore, a thorough, multidisciplinary assessment to determine disease activity and degree of impairment is required to optimize patient management. Nevertheless, the management of thoracic involvement-particularly ILD-is challenging due to the heterogeneity of disease pathogenesis, the variety of patterns of interstitial pneumonia and the paucity of randomized controlled clinical trials of pharmacological intervention. Further studies are needed to better understand the pathogenesis of these conditions, which in turn is instrumental to the development of more efficacious therapies
Níveis de metano e perdas energéticas em bovinos de corte, suplementados ou não, em pastagem de capim mombaça (Panicum maximum cv. Mombaça).
Objetivou-se avaliar o impacto da suplementação protéico-energética na emissão de metano (CH4) de novilhos, durante a recria, em pastagem de capim-mombaça. Os tratamentos avaliados foram: T0 ? Apenas suplementação mineral; T1 ? Suplementação protéico-energética. Utilizou-se a técnica do gás traçador interno hexafluoreto de enxofre (SF6) para estimar a emissão diária de CH4. Foram utilizados 20 animais, sendo dez de cada tratamento, em dois ensaios, com medição de CH4 em cinco dias consecutivos. Na análise estatística dos dados de emissão de CH4 , utilizou-se a metodologia de modelos mistos para medidas repetidas do SAS. Os animais foram também avaliados quanto à eficiência de utilização do alimento, utilizando-se como critério o consumo alimentar residual (CAR). Animais suplementados e não suplementados não diferiram (P>0,05) quanto à produção diária de metano e quanto à perda total diária de energia na forma de CH4. Entretanto, quando a perda de energia foi expressa em g/kg de matéria seca consumida (21,51 vs. 29,76 g/kg) e como porcentagem da energia bruta (EB) ingerida (6,36 versus 8,59 %), os animais suplementados tiveram menores perdas (P0,05) quanto aos níveis de emissão de metano (total ou por kg de matéria seca ? MS ingerida). Assim, conclui-se que: a suplementação com concentrado age de forma efetiva na mitigação da emissão de metano; diferenças no CAR não podem ser atribuídas a diferenças nos níveis de emissão de metano
A global fit to determine the pseudoscalar mixing angle and the gluonium content of the eta' meson
We update the values of the eta-eta' mixing angle and of the eta' gluonium
content by fitting our measurement R_phi = BR(phi to eta' gamma)/ BR(phi to eta
gamma) together with several vector meson radiative decays to pseudoscalars (V
to P gamma), pseudoscalar mesons radiative decays to vectors (P to V gamma) and
the eta' to gamma gamma, pi^0 to gamma gamma widths. From the fit we extract a
gluonium fraction of Z^2_G = 0.12 +- 0.04, the pseudoscalar mixing angle psi_P
= (40.4 +- 0.6) degree and the phi-omega mixing angle psi_V = (3.32 +- 0.09)
degree. Z^2_G and psi_P are fairly consistent with those previously published.
We also evaluate the impact on the eta' gluonium content determination of
future experimental improvements of the eta' branching ratios and decay width.Comment: 13 pages, 7 figures to submit to JHE
Study of the process e+e- -> omega pi0 in the phi-meson mass region with the KLOE detector
We have studied the e+e- -> omegapi0 cross section in the sqrt(s) interval
1000-1030 MeV using the pi+pi-pi0pi0 and pi0pi0gamma final states with a sample
of ~600 pb^-1 collected with the KLOE detector at DAFNE. By fitting the
observed interference pattern around M_phi for both final states, we extract
the ratio of the decay widths Gamma(omega->pi0gamma)/Gamma(omega->pi+pi-pi0) =
0.0897 +- 0.0016 and derive the branching fractions BR(omega -> pi+pi-pi0)=
(90.24 +- 0.19)%, BR(omega -> pi0gamma) = (8.09 +- 0.14)%. The parameters
describing the e+e- -> omegapi0 reaction around M_\phi are also used to extract
the branching fraction for the OZI and G-parity violating phi -> omegapi0
decay: BR(phi->omegapi0) = (4.4 +- 0.6)x10^-5.Comment: 12 Pages, 4 figures, submitted to Physics Letter
Precision Measurement of KS Meson Lifetime with the KLOE detector
Using a large sample of pure, slow, short lived K0 mesons collected with KLOE
detector at DaFne, we have measured the KS lifetime. From a fit to the proper
time distribution we find tau = (89.562 +- 0.029_stat +- 0.043_syst) ps. This
is the most precise measurement today in good agreement with the world average
derived from previous measurements. We observe no dependence of the lifetime on
the direction of the Ks.Comment: 5 pages, 7 figure
Search for the K_S -> e+e- decay with the KLOE detector
We present the result of a direct search for the decay K_S -> e+e-, obtained
with a sample of e+e- -> phi -> K_S K_L events produced at DAFNE, the Frascati
phi-factory, for an integrated luminosity of 1.9 fb^-1. The search has been
performed using a pure K_S beam tagged by the simultaneous detection of a K_L
interaction in the calorimeter. Background rejection has been optimized by
using both kinematic and particle identification cuts. We find BR(K_S -> e+e-)
< 9x10^-9 at 90% CL, which improves by an order of magnitude on the previous
best limit.Comment: 13 pages, 11 figures, submitted to Physics Letters
Nanoscale Assembly of Functional Peptides with Divergent Programming Elements
Self-assembling peptides are being applied both in the biomedical area and as building blocks in nanotechnology. Their applications are closely linked to their modes of self-assembly, which determine the functional nanostructures that they form. This work brings together two structural elements that direct nanoscale self-association in divergent directions: proline as a β-breaker and the β-structure-associated diphenylalanine motif, into a single tripeptide sequence. Amino acid chirality was found to resolve the tension inherent to these conflicting self-assembly instructions. Stereoconfiguration determined the ability of each of the eight possible Pro-Phe-Phe stereoisomers to self-associate into diverse nanostructures, including nanoparticles, nanotapes, or fibrils, which yielded hydrogels with gel-to-sol transition at a physiologically relevant temperature. Three single-crystal structures and all-atom molecular dynamics simulations elucidated the ability of each peptide to establish key interactions to form long-range assemblies (i,e., stacks leading to gelling fibrils), medium-range assemblies (i.e., stacks yielding nanotapes), or short-range assemblies (i.e., dimers or trimers that further associated into nanoparticles). Importantly, diphenylalanine is known to serve as a binding site for pathological amyloids, potentially allowing these heterochiral systems to influence the fibrillization of other biologically relevant peptides. To probe this hypothesis, all eight Pro-Phe-Phe stereoisomers were tested in vitro on the Alzheimer's disease-associated Aβ(1-42) peptide. Indeed, one nonfibril-forming stereoisomer effectively inhibited Aβ fibrillization through multivalent binding between diphenylalanine motifs. This work thus defined heterochirality as a useful feature to strategically develop future therapeutics to interfere with pathological processes, with the additional value of resistance to protease-mediated degradation and biocompatibility
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