Non-conditioned generation of Schroedinger cat states in a cavity

We investigate the dynamics of a two-level atom in a cavity filled with a nonlinear medium. We show that the atom-field detuning $\delta$ and the nonlinear parameter $\chi^{(3)}$ may be combined to yield a periodic dynamics and allowing the generation of almost exact superpositions of coherent states ({\sl Schr\"odinger} cats). By analysing the atomic inversion and the field purity, we verify that any initial atom-field state is recovered at each revival time, and that a coherent field interacting with an excited atom evolves to a superposition of coherent states at each collapse time. We show that a mixed field state (statistical mixture of two coherent states) evolves towards a pure field state ({\sl Schr\"odinger} cat) as well. We discuss the validity of those results by using the field fidelity and the {\sl Wigner} function.Comment: REVTeX4, 8 pages, 7 figures, link to an external animation fil

Space shuttle abort separation pressure investigation. Volume 2, Part B: Orbiter data at Mach 5

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High-sensitivity force measurement using entangled probes

We show the possibility to improve the measurement sensitivity of a weak force by using two meters in an entangled state. This latter can be achieved by exploiting radiation pressure effects.Comment: ReVTeX file, 11 pages, 2 eps figure

Effect of tooth profile modification on the durability of planetary hub gears

Planetary systems offer the advantage of desired speed-torque variation with a lighter, compact and coaxial construction than the traditional gear trains. Frictional losses and Noise, Vibration and Harshness (NVH) refinement are the main concerns. Modification of gear teeth geometry to reduce friction between the mating teeth flanks of vehicular planetary hubs, as well as refining NVH under varying load-speed conditions is one of the remedial actions. However, implementing modifications can result in reduced structural integrity and system durability. Therefore, a contradiction may arise between assuring a high degree of durability and achieving better transmission efficiency, which necessitates detailed system optimisation. An integrated multi-disciplinary analytical approach, including tribology and sub-surface stress analysis is developed. As a preliminary step, Tooth Contact Analysis (TCA) is performed to obtain contact footprint shape of meshing gear teeth pairs, as well as contact kinematics and applied load distribution. Then, an analytical time-efficient Elastohydrodynamic Lubrication (EHL) analysis of elliptical point contact of crowned spur gear tooth is carried out to observe the effect of gear tip relief modification upon planetary hub sub-surface stresses

Cav1 Suppresses Tumor Growth and Metastasis in a Murine Model of Cutaneous SCC through Modulation of MAPK/AP-1 Activation

Caveolin-1 (Cav1) is a scaffolding protein that serves to regulate the activity of several signaling molecules. Its loss has been implicated in the pathogenesis of several types of cancer, but its role in the development and progression of cutaneous squamous cell carcinoma (cSCC) remains largely unexplored. Herein, we use the keratinocyte cell line PAM212, a murine model of cSCC, to determine the function of Cav1 in skin tumor biology. We first show that Cav1 overexpression decreases cell and tumor growth, whereas Cav1 knockdown increases these attributes in PAM212 cells. In addition, Cav1 knockdown increases the invasive ability and incidence of spontaneous lymph node metastasis. Finally, we demonstrate that Cav1 knockdown increases extracellular signaling–related kinase 1/2 mitogen-activated protein kinase/activator protein-1 pathway activation. We attribute the growth and invasive advantage conferred by Cav1 knockdown to increased expression of activator protein-1 transcriptional targets, including cyclin D1 and keratin 18, which show inverse expression in PAM212 based on the expression level of Cav1. In summary, we demonstrate that loss of Cav1 affects several characteristics associated with aggressive human skin tumors and that this protein may be an important modulator of tumor growth and invasion in cSCC

Suspended particles are hotspots of microbial remineralization in the ocean's twilight zone

The sinking of photosynthetically produced organic carbon from the ocean surface to its interior is a significant term in the global carbon cycle. Most sinking organic carbon is, however, remineralized in the mesopelagic zone (∼100 m–1000 m), thereby exerting control over ocean-atmosphere carbon dioxide (CO2) partitioning and hence global climate. Sinking particles are considered hotspots of microbial respiration in the dark ocean. However, our observations in the contrasting Scotia Sea and the Benguela Current show that >90% of microbial remineralisation is associated with suspended, rather than sinking, organic matter, resulting in rapid turnover of the suspended carbon pool and demonstrating its central role in mesopelagic carbon cycling. A non-steady-state model indicates that temporally variable particle fluxes, particle injection pumps and local chemoautotrophy are necessary to help balance the observed mesopelagic respiration. Temperature and oxygen exert control over microbial respiration, particularly for the suspended fraction, further demonstrating the susceptibility of microbial remineralisation to the ongoing decline in oxygen at mid-ocean depths. These observations suggest a partial decoupling of carbon cycling between non-sinking and fast-sinking organic matter, challenging our understanding of how oceanic biological processes regulate climate

Nature as a 'Lifeline': The Power of Photography when Exploring the Experiences of Older Adults living with Memory Loss and Memory Concerns.

The visual is an underutilised modality through which to investigate experiences of memory loss in older people. We describe a visual ethnography with older adults experiencing subjective or objective memory loss, receiving a cognitive wellbeing group intervention designed to prevent cognitive decline and dementia (APPLE-Tree programme). We aimed to explore lived experiences of people with memory concerns, how participants engaged with this photography and co-design project, and how collaboration with an artist/photographer enhanced this process. Nineteen participants shared photographs reflecting what they valued in their daily lives, their experiences of memory concerns, and the intervention. Fourteen participated in qualitative photo-elicitation interviews, and thirteen collaborated with a professional artist/photographer to co-create an exhibition, in individual meetings and workshops, during which a researcher took ethnographic field notes. Eight participants were re-interviewed after the exhibition launch. We contextualise images produced by participants in relation to discourses around the visual and ageing and highlight their relationship with themes developed through thematic analysis that interconnects photographic, observational and interview data. We present themes around the use of photographs to: (1) celebrate connections to nature as a lifeline; (2) anchor lives within the context of relationships with family; (3) reflect on self and identity, enduring through ageing, memory concerns, pandemic, and ageing stereotypes. We explore visual research as a powerful tool for eliciting meaningful accounts from older adults experiencing cognitive change and to connect the arts and social sciences within ageing studies

Space shuttle abort separation pressure investigation. Volume 6: Orbiter data at Mach 2

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Investigation of the McDonnell-Douglas orbiter and booster shuttle models in proximity at Mach numbers 2.0 to 6.0. Volume 7: Proximity data at Mach 4 and 6, interference free and launch vehicle data

Aerodynamic data obtained from a space shuttle abort stage separation wind tunnel test are presented. The .00556 scale models of the orbiter and booster configuration were tested in close proximity using dual balances during the time period of April 21 to April 27 1971. Data were obtained for both booster and orbiter over an angle of attack range from -10 to 10 deg for zero degree sideslip angle. The models were tested at several relative incidence angles and separation distances and power conditions. Plug nozzles utilizing air were used to simulate booster and orbiter plumes at various altitudes along a nominal ascent trajectory. Powered conditions were 100, 50, 25 and 0 percent of full power for the orbiter and 100, 50 and 0 percent of full power for the booster. Pitch control effectiveness data were obtained for both booster and orbiter with power on and off. In addition, launch vehicle data with and without booster power were obtained utilizing a single balance in the booster model. Data were also obtained with the booster canard off in close proximity and for the launch configuration