Hardiness and Culture: a Study with Reference to 3 Cs of Kobasa

The concept of Hardiness was first given by Suzanne C. Kobasa (1979) as a personality style or pattern associated with continued good health and performance under stress. According to her, hardy people are buffered against stressful life situations because they engage in certain affective, cognitive, and behavioral responses. In her foundational paper entitled ‘Stressful life events, personality, and health: An inquiry into hardiness\u27, published in the Journal of Personality and Social Psychology in 1979, Suzanne C. Kobasa introduced the concept of psychological hardiness and suggested that hardiness moderates the relationship between stressful life events and illness. Kobasa characterized hardiness as comprising of three components or the 3C\u27s: Commitment, Control, and Challenge. This paper is an attempt to study these hardiness components and the subsequent additions to the research work in the area of study made by such succeeding scholars as Salvatore et al., (2005). In 2005, Maddi added Connection as the 4th C and in my paper, I have proposed Culture as the 5th C, a component relevant especially to the Indian context

An adaptive two-level method for hypersingular integral equations in R3R^3

In this paper an a posteriori error estimate for hypersingular integral equations is derived by using hierarchical basis techniques. Based on the properties of a two-level additive Schwarz method easily computable local error indicators are obtained. An algorithm for adaptive error control which allows anisotropic refinements of the boundary elements is formulated and numerical results are included

The fitness of pseudomonas aeruginosa quorum sensing signal cheats is influenced by the diffusivity of the environment

Experiments examining the social dynamics of bacterial quorum sensing (QS) have focused on mutants which do not respond to signals and the role of QS-regulated exoproducts as public goods. The potential for QS signal molecules to themselves be social public goods has received much less attention. Here, we analyze how signal-deficient (lasI) mutants of the opportunistic pathogen Pseudomonas aeruginosa interact with wild-type cells in an environment where QS is required for growth. We show that when growth requires a “private” intracellular metabolic mechanism activated by the presence of QS signal, lasI mutants act as social cheats and outcompete signal-producing wild-type bacteria in mixed cultures, because they can exploit the signals produced by wild-type cells. However, reducing the ability of signal molecules to diffuse through the growth medium results in signal molecules becoming less accessible to mutants, leading to reduced cheating. Our results indicate that QS signal molecules can be considered social public goods in a way that has been previously described for other exoproducts but that spatial structuring of populations reduces exploitation by noncooperative signal cheats

Modular Localization of Massive Particles with "Any" Spin in d=2+1

We discuss a concept of particle localization which is motivated from quantum field theory, and has been proposed by Brunetti, Guido and Longo and by Schroer. It endows the single particle Hilbert space with a family of real subspaces indexed by the space-time regions, with certain specific properties reflecting the principles of locality and covariance. We show by construction that such a localization structure exists also in the case of massive anyons in d=2+1, i.e. for particles with positive mass and with arbitrary spin s in the reals. The construction is completely intrinsic to the corresponding ray representation of the (proper orthochronous) Poincare group. Our result is of particular interest since there are no free fields for anyons, which would fix a localization structure in a straightforward way. We present explicit formulas for the real subspaces, expected to turn out useful for the construction of a quantum field theory for anyons. In accord with well-known results, only localization in string-like, instead of point-like or bounded, regions is achieved. We also prove a single-particle PCT theorem, exhibiting a PCT operator which acts geometrically correctly on the family of real subspaces

Endogenous Transmembrane TNF-Alpha Protects Against Premature Senescence in Endothelial Colony Forming Cells

RATIONALE: Transmembrane tumor necrosis factor-α (tmTNF-α) is the prime ligand for TNF receptor 2, which has been shown to mediate angiogenic and blood vessel repair activities in mice. We have previously reported that the angiogenic potential of highly proliferative endothelial colony-forming cells (ECFCs) can be explained by the absence of senescent cells, which in mature endothelial cells occupy >30% of the population, and that exposure to a chronic inflammatory environment induced premature, telomere-independent senescence in ECFCs. OBJECTIVE: The goal of this study was to determine the role of tmTNF-α in the proliferation of ECFCs. METHODS AND RESULTS: Here, we show that tmTNF-α expression on ECFCs selects for higher proliferative potential and when removed from the cell surface promotes ECFC senescence. Moreover, the induction of premature senescence by chronic inflammatory conditions is blocked by inhibition of tmTNF-α cleavage. Indeed, the mechanism of chronic inflammation-induced premature senescence involves an abrogation of tmTNF/TNF receptor 2 signaling. This process is mediated by activation of the tmTNF cleavage metalloprotease TNF-α-converting enzyme via p38 MAP kinase activation and its concurrent export to the cell surface by means of increased iRhom2 expression. CONCLUSIONS: Thus, we conclude that tmTNF-α on the surface of highly proliferative ECFCs plays an important role in the regulation of their proliferative capacity

An alternative to the gauge theoretic setting

The standard formulation of gauge theories results from the Lagrangian (functional integral) quantization of classical gauge theories. A more intrinsic qunantum theoretical access in the spirit of Wigner's representation theory shows that there is a fundamental clash between the pointlike localization of zero mass (vector, tensor) potentials and the Hilbert space (positivity, unitarity) structure of QT. The quantization approach has no other way than to stay with pointlike localization and sacrifice the Hilbert space whereas the approach build on the intrinsic quantum concept of modular localization keeps the Hilbert space and trades the conflict creating pointlike generation with the tightest consistent localization:: semiinfinite spacelike string localization. Whereas these potentials in the presence of interactions stay quite close to associated pointlike field strength, the interacting matter fields to which they are coupled bear the brunt of the nonlocal aspect in that they are string.generated in a way which cannot be undone by any differentiation. The new stringlike approach to gauge theory also revives the idea of a Schwinger-Higgs screening mechanism as a deeper and less metaphoric description of the Higgs spontaneous symmetry breaking and its accompanying tale about "God's particle" and its mass generation for all other particles.Comment: 26 page

Entanglement Entropy of Random Fractional Quantum Hall Systems

The entanglement entropy of the $\nu = 1/3$ and $\nu = 5/2$ quantum Hall states in the presence of short range random disorder has been calculated by direct diagonalization. A microscopic model of electron-electron interaction is used, electrons are confined to a single Landau level and interact with long range Coulomb interaction. For very weak disorder, the values of the topological entanglement entropy are roughly consistent with expected theoretical results. By considering a broader range of disorder strengths, the fluctuation in the entanglement entropy was studied in an effort to detect quantum phase transitions. In particular, there is a clear signature of a transition as a function of the disorder strength for the $\nu = 5/2$ state. Prospects for using the density matrix renormalization group to compute the entanglement entropy for larger system sizes are discussed.Comment: 29 pages, 16 figures; fixed figures and figure captions; revised fluctuation calculation

String-localized Quantum Fields and Modular Localization

We study free, covariant, quantum (Bose) fields that are associated with irreducible representations of the Poincar\'e group and localized in semi-infinite strings extending to spacelike infinity. Among these are fields that generate the irreducible representations of mass zero and infinite spin that are known to be incompatible with point-like localized fields. For the massive representation and the massless representations of finite helicity, all string-localized free fields can be written as an integral, along the string, of point-localized tensor or spinor fields. As a special case we discuss the string-localized vector fields associated with the point-like electromagnetic field and their relation to the axial gauge condition in the usual setting.Comment: minor correction