Hepatoprotective Effect of Cassia Fistula Linn.

A number of herbal preparations are used throughout the world for the management of the hepatic disorders. However, many of them have not been investigated for their described effects. Cassia fistula Linn. is one such drug used in the treatment of hepatitis in folk medicine. Therefore, an attempt was made to investigate the hepatoprotective effect of leaves and bark of Cassia fistula against carbon tetrachloride (CCl4) induced hepatotoxicity in rats. Sixty albino Wistar rats were divided into six equal groups of 10. Four groups received extracts leaves/bark of Cassia fistula and intraperitoneal (i.p.) CCl4 (0.2 ml/100 g) either before or after administration of extracts. Two groups were controls, one treated with CCl4 and one with normal saline. Liver damage was assessed by plasma concentration of bilirubin and enzyme activities of aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase. Treatment with aqueous extract of leaves and bark significantly reduced CCl4 -induced elevation in plasma enzyme and bilirubin concentration in rats. This study demonstrated that CCl4 -induced liver damage in rats can be ameliorated by treatment of extracts from leaves and bark

Impacts of leaf extract of Catharanthus roseus (L.) on seed mycoflora of soybean

Present research communication deals with study impact of Catharanthus roseus (L.) leaf extract on seed borne fungi of soybean seeds.&nbsp

Role of Nitya Virechan and Shaman Aushadhi in Dadru Kushtha w.r.t. Tinia Corporis - A Case Study

Ayurveda have been classified all the skin diseases under the broad heading of ‘Kushta’ which were sub classified into Mahakushta and Kshudrakushta. Hetu (Causative factors) of Dadru Kushta involves Vishamashana (Incompatible food), Vegavidharana (suppression of natural urges), Diwaswapa (daytime sleeping), intake of Atilavana, Atitikshnaahar (excessive salty or spicy food), intake of contaminated food, drinking cold water just after physical work or Atapsevana (exposure to sunlight). Lakshanas of Dadru include Kandu (Itching), Utsanna (elevated circular lesions), Mandala (Circular Patches), Raaga (Erythema), and Pidakas (Papule). The Samprapti of Dadru mainly involves vitiation of Pitta-kapha Doshas and Dushti of rasa and Raktavaha Strotas. A 56 year old male patient, came to OPD with the complaints of reddish circular patch on chest and back with sever itching and burning sensation since last 3 months. After examination patient was diagnosed as case of Dadru Kushth and was treated with Ayurvedic management protocol i.e., Abyantar Snehan with Nitya Virechan, Shaman Aushdhi and Bahirparimarjan Chikitsa for 1 month and was taken follow up after 14days. Dietary restriction was advised to avoid spicy and junk food along with personal hygiene to be maintained. After complete treatment of 1 month patient was assessed with parameter like raga (redness), Kandu (itching), Daha (burning sensation), and Utsana Mandal on a grade from 0 to 3 and there was significant improvement was noted. From this case study it can be concluded that use of Nitya Virechan with Snehapan with Panchatikta Ghruta and Shaman Aushdhi along with Bahya Chikitsa can treat Dadru Kushta

Control of fungi associated with green gram seeds by using Trichoderma species

In the recent years, the biological control has received a worldwide attention and is being integrated effectively with other pesticides. Moreover, in the context of environmental pollution the use of biological agents is considered quite safe. Three Trichoderma species viz. T. viride, T. harzionum and Trichoderma sp. (Local) were evaluated against Aspergillus niger, A. flavus, Alternaria tenuis, Fusarium oxysporium, Penicillium citrinum, Drechslera longirostrata and Fusarium solani. All the Trichoderma species were effective against above pathogens but Trichoderma (Local) proved to be superior for inhibition of the above pathogen as compared to other Trichoderma species

Mycoflora associated with Pigeon pea and Chickpea

Pigeonpea (Cajanu. cajan.) and Chick Pea (Cicer arietinum) are major pulse crops grown in India. The seed mycoflora was screened by using agar plate method. seeds of varieties of these pulse crops was used in the study and results were obtained from untreated and treated seeds. The untreated seeds were found to be associated with highest percent incidence of mycoflora. In case of untreated seeds the percent incidence of Aspergillus flavus (30%) was the highest followed by     A. niger (25%), Penicillium notatum (20 %), Cladosporium herbarum (18%), where as all other fungi were within the range of (3 to 15%)

Thoracic wall lipoblastoma: a rare case with rare presentation

Lipoblastoma is a rare benign tumor occuring in infancy and early childhood. It is usually located on the extremities but can be found anywhere on the body. Normally, it is well capsulated, but when it is multicentric in origin and diffused in nature it is known as lipoblastomatosis. We report a case of a 1-year-old boy who presented with a huge swelling on the back that, on postoperative histological examination, was diagnosed as lipoblastoma.Keywords: infancy, lipoblastoma, lipoblastomatosi

Evaluation of leaf extract of Lantana camara aginast seed mycoflora - biopesticides approach

The Seed treatment with pant extract of Lantana camara does not have any adverse effect on the germinated of seeds even after the treatment for 30 minutes. The seed were treated with aqneous extract, alcoholic extract, and ethyl acetate extract of Lantana camara leavers for 5 minutes, 15 minutes and 30 minutes. It is evident that the treatment of ethyl acetate extract for 30 minutes inhibited the growth of dominant fungi like curvularia lunata A.flavus, A.niger and fusarium moniliforme. So the ethylacetate extract of leaves of Lantana camara can be utilised for the biological control of seeds borne fungi of soybean. So the seed treatment of plant extract will not cause any problem of pollution and the chemical of plant extracts are easily degraded in the soil, So the plant extract of Lantana camara can be used as biopesticide.&nbsp

�Synchronous Modulation In An Inverter Fed Motor Drive For Recovering Energy From Matching Long Cable ��

In this paper, we understood the significance of bit rate investigation of the approaching bundle. We additionally comprehended that if the bit rate is not dissected, then there is wastefulness in system execution. This examination study will demonstrate a decent base for further research in the territory of bit rate investigation of bundle landings. In this paper we had broke down the throughput, parcel delay, bundle conveyance proportion, jitter, vitality devoured and the examination as for no. of bundles sent is performed. Thusly we can accomplish the objective of enhancing bit rate bundle investigation coming about system proficiency. The most recent adaptation of system test system will be most useful in development of system and follow document in it is additionally helpful. In future, the framework could be created on the equipment and the execution assessment could be checked continuously. The deferral is an imperative parameter if there should arise an occurrence of ongoing activity. The postponement ought to be diminished or else it prompts unsafe circumstance on the off chance that hard continuous frameworks. Thus, it would be an awesome future work to build up the framework on the equipment and checking of execution assessment progressively

Myeloid Wnt ligands are required for normal development of dermal lymphatic vasculature

Resident tissue myeloid cells play a role in many aspects of physiology including development of the vascular systems. In the blood vasculature, myeloid cells use VEGFC to promote angiogenesis and can use Wnt ligands to control vascular branching and to promote vascular regression. Here we show that myeloid cells also regulate development of the dermal lymphatic vasculature using Wnt ligands. Using myeloid-specific deletion of the WNT transporter Wntless we show that myeloid Wnt ligands are active at two distinct stages of development of the dermal lymphatics. As lymphatic progenitors are emigrating from the cardinal vein and intersomitic vessels, myeloid Wnt ligands regulate both their numbers and migration distance. Later in lymphatic development, myeloid Wnt ligands regulate proliferation of lymphatic endothelial cells (LEC) and thus control lymphatic vessel caliber. Myeloid-specific deletion of WNT co-receptor Lrp5 or Wnt5a gain-of-function also produce elevated caliber in dermal lymphatic capillaries. These data thus suggest that myeloid cells produce Wnt ligands to regulate lymphatic development and use Wnt pathway co-receptors to regulate the balance of Wnt ligand activity during the macrophage-LEC interaction

The evolutionary signal in metagenome phyletic profiles predicts many gene functions

Background. The function of many genes is still not known even in model organisms. An increasing availability of microbiome DNA sequencing data provides an opportunity to infer gene function in a systematic manner. Results. We evaluated if the evolutionary signal contained in metagenome phyletic profiles (MPP) is predictive of a broad array of gene functions. The MPPs are an encoding of environmental DNA sequencing data that consists of relative abundances of gene families across metagenomes. We find that such MPPs can accurately predict 826 Gene Ontology functional categories, while drawing on human gut microbiomes, ocean metagenomes, and DNA sequences from various other engineered and natural environments. Overall, in this task, the MPPs are highly accurate, and moreover they provide coverage for a set of Gene Ontology terms largely complementary to standard phylogenetic profiles, derived from fully sequenced genomes. We also find that metagenomes approximated from taxon relative abundance obtained via 16S rRNA gene sequencing may provide surprisingly useful predictive models. Crucially, the MPPs derived from different types of environments can infer distinct, non-overlapping sets of gene functions and therefore complement each other. Consistently, simulations on > 5000 metagenomes indicate that the amount of data is not in itself critical for maximizing predictive accuracy, while the diversity of sampled environments appears to be the critical factor for obtaining robust models. Conclusions. In past work, metagenomics has provided invaluable insight into ecology of various habitats, into diversity of microbial life and also into human health and disease mechanisms. We propose that environmental DNA sequencing additionally constitutes a useful tool to predict biological roles of genes, yielding inferences out of reach for existing comparative genomics approaches