164 research outputs found

    Use of a Portable Sawmill for Forestry Instruction

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    The Arthur Temple College of Forestry and Agriculture at Stephen F. Austin State University in Nacogdoches, TX, has implemented an experiential learning exercise to improve student learning related to the forest products industry. During the week-long sophomore- or junior-level course Harvesting and Processing, forestry students tour multiple wood products facilities such as sawmills. These mills use complex technologies to maximize the lumber produced from each log, and students were having difficulty understanding the underlying concepts. As part of this course beginning in 2012, students began working in teams to estimate the lumber that will be recovered from a log and then actually sawing their own log using a portable sawmill. Since the introduction of this experiential learning project, student comments, instructor observations, and an increase in the mean course grades suggest that the sawmill activity is not only popular among students, it also allows for a fun, competitive, and engaging way to prepare future natural resource managers for their careers

    Web-Based Spatial Decision Support System and Watershed Management with a Case Study

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    In order to maintain a proper balance between development pressure and water resources protection, and also to improve public participation, efficient tools and techniques for soil and water conservation projects are needed. This paper describes the development and application of a web-based watershed management spatial decision support system, WebWMPI. The WebWMPI uses the Watershed Management Priority Indices (WMPI) approach which is a prioritizing method for watershed management planning and it integrates land use/cover, hydrological data, soils, slope, roads, and other spatial data. The land is divided into three categories: Conservation Priority Index (CPI) land, Restoration Priority Index (RPI) land, and Stormwater Management Priority Index (SMPI) land. Within each category, spatial factors are rated based on their influence on water resources and critical areas can be identified for soil conservation, water quality protection and improvement. The WebWMPI has user-friendly client side graphical interfaces which enable the public to interactively run the server side Geographic Information System to evaluate different scenarios for watershed planning and management. The system was applied for Dry Run Creek watershed (Cedar Falls, Iowa, US) as a demonstration and it can be easily used in other watersheds to prioritize crucial areas and to increase public participation for soil and water conservation projects

    educationUndergraduate: Journal of undergraduate research in education (Volume 9)

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    Contents Page Bridging pedagogical discontinuity: to what extent can play-based learning be sustained beyond children’s transition to Year 1? Philip Nicholson: BA (Hons) Education Studies and Sport Teacher talk or teaching talk? Teacher perspectives on effective strategies for the teaching of speaking and listening in primary classrooms. Sarah McBroom: BA (Hons) Education Studies and Sport Making marks: the road to literacy? An exploratory study into the role of the practitioner and the strategies used to support children’s emergent writing in the early years. Louise Tomlinson: BA (Hons) Early Childhood Studies How does the Maths Makes Sense scheme affect key stage one pupils’ confidence in mathematics? Aliya Arthur: BA (Hons) Primary Education The perceived benefits experienced by families as a result of engaging with Sure Start Children's Centres Danielle Camp: BA (Hons): Psychology and Early Childhood Studies How can positive inclusion and strategic pastoral care lead to a reduction in permanent exclusions in secondary schools? A review of one schools’ journey from Rhetoric to Reality Lynda Martin: BA (Hons) Psychology and Special Educational Needs and Inclusio

    Homozygous staggerer (sg/sg) mice display improved insulin sensitivity and enhanced glucose uptake in skeletal muscle

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    Homozygous staggerer (sg/sg) mice, which have decreased and dysfunctional Ror alpha (also known as Rora) expression in all tissues, display a lean and dyslipidaemic phenotype. They are also resistant to (high fat) diet-induced obesity. We explored whether retinoic acid receptor-related orphan receptor (ROR) alpha action in skeletal muscle was involved in the regulation of glucose metabolism

    Reversal of the ΔdegP Phenotypes by a Novel rpoE Allele of Escherichia coli

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    RseA sequesters RpoE (σE) to the inner membrane of Escherichia coli when envelope stress is low. Elevated envelope stress triggers RseA cleavage by the sequential action of two membrane proteases, DegS and RseP, releasing σE to activate an envelope stress reducing pathway. Revertants of a ΔdegP ΔbamB strain, which fails to grow at 37°C due to high envelope stress, harbored mutations in the rseA and rpoE genes. Null and missense rseA mutations constitutively hyper-activated the σE regulon and significantly reduced the major outer membrane protein (OMP) levels. In contrast, a novel rpoE allele, rpoE3, resulting from the partial duplication of the rpoE gene, increased σE levels greater than that seen in the rseA mutant background but did not reduce OMP levels. A σE-dependent RybB::LacZ construct showed only a weak activation of the σE pathway by rpoE3. Despite this, rpoE3 fully reversed the growth and envelope vesiculation phenotypes of ΔdegP. Interestingly, rpoE3 also brought down the modestly activated Cpx envelope stress pathway in the ΔdegP strain to the wild type level, showing the complementary nature of the σE and Cpx pathways. Through employing a labile mutant periplasmic protein, AcrAL222Q, it was determined that the rpoE3 mutation overcomes the ΔdegP phenotypes, in part, by activating a σE-dependent proteolytic pathway. Our data suggest that a reduction in the OMP levels is not intrinsic to the σE-mediated mechanism of lowering envelope stress. They also suggest that under extreme envelope stress, a tight homeostasis loop between RseA and σE may partly be responsible for cell death, and this loop can be broken by mutations that either lower RseA activity or increase σE levels

    The Pseudomonas Quinolone Signal (PQS) Balances Life and Death in Pseudomonas aeruginosa Populations

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    When environmental conditions deteriorate and become inhospitable, generic survival strategies for populations of bacteria may be to enter a dormant state that slows down metabolism, to develop a general tolerance to hostile parameters that characterize the habitat, and to impose a regime to eliminate damaged members. Here, we provide evidence that the pseudomonas quinolone signal (PQS) mediates induction of all of these phenotypes. For individual cells, PQS, an interbacterial signaling molecule of Pseudomonas aeruginosa, has both deleterious and beneficial activities: on the one hand, it acts as a pro-oxidant and sensitizes the bacteria towards oxidative and other stresses and, on the other, it efficiently induces a protective anti-oxidative stress response. We propose that this dual function fragments populations into less and more stress tolerant members which respond differentially to developing stresses in deteriorating habitats. This suggests that a little poison may be generically beneficial to populations, in promoting survival of the fittest, and in contributing to bacterial multi-cellular behavior. It further identifies PQS as an essential mediator of the shaping of the population structure of Pseudomonas and of its response to and survival in hostile environmental conditions

    Identification and validation of the pathways and functions regulated by the orphan nuclear receptor, ROR alpha1, in skeletal muscle

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    The retinoic acid receptor-related orphan receptor (ROR) alpha has been demonstrated to regulate lipid metabolism. We were interested in the RORα1 dependent physiological functions in skeletal muscle. This major mass organ accounts for ∼40% of the total body mass and significant levels of lipid catabolism, glucose disposal and energy expenditure. We utilized the strategy of targeted muscle-specific expression of a truncated (dominant negative) RORα1ΔDE in transgenic mice to investigate RORα1 signaling in this tissue. Expression profiling and pathway analysis indicated that RORα influenced genes involved in: (i) lipid and carbohydrate metabolism, cardiovascular and metabolic disease; (ii) LXR nuclear receptor signaling and (iii) Akt and AMPK signaling. This analysis was validated by quantitative PCR analysis using TaqMan low-density arrays, coupled to statistical analysis (with Empirical Bayes and Benjamini–Hochberg). Moreover, westerns and metabolic profiling were utilized to validate the genes, proteins and pathways (lipogenic, Akt, AMPK and fatty acid oxidation) involved in the regulation of metabolism by RORα1. The identified genes and pathways were in concordance with the demonstration of hyperglycemia, glucose intolerance, attenuated insulin-stimulated phosphorylation of Akt and impaired glucose uptake in the transgenic heterozygous Tg-RORα1ΔDE animals. In conclusion, we propose that RORα1 is involved in regulating the Akt2-AMPK signaling pathways in the context of lipid homeostasis in skeletal muscle
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