Perturbative Quantum Gravity And Newton's Law On A Flat Robertson-Walker Background

We derive the Feynman rules for the graviton in the presence of a flat Robertson-Walker background and give explicit expressions for the propagator in the physically interesting cases of inflation, radiation domination, and matter domination. The aforementioned background is generated by a scalar field source which should be taken to be dynamical. As an elementary application, we compute the corrections to the Newtonian gravitational force in the present matter dominated era and conclude -- as expected -- that they are negligible except for the largest scales.Comment: 32 pages, plain Te

Efficient Computation of Sequence Mappability

Sequence mappability is an important task in genome re-sequencing. In the $(k,m)$-mappability problem, for a given sequence $T$ of length $n$, our goal is to compute a table whose $i$th entry is the number of indices $j \ne i$ such that length-$m$ substrings of $T$ starting at positions $i$ and $j$ have at most $k$ mismatches. Previous works on this problem focused on heuristic approaches to compute a rough approximation of the result or on the case of $k=1$. We present several efficient algorithms for the general case of the problem. Our main result is an algorithm that works in $\mathcal{O}(n \min\{m^k,\log^{k+1} n\})$ time and $\mathcal{O}(n)$ space for $k=\mathcal{O}(1)$. It requires a carefu l adaptation of the technique of Cole et al.~[STOC 2004] to avoid multiple counting of pairs of substrings. We also show $\mathcal{O}(n^2)$-time algorithms to compute all results for a fixed $m$ and all $k=0,\ldots,m$ or a fixed $k$ and all $m=k,\ldots,n-1$. Finally we show that the $(k,m)$-mappability problem cannot be solved in strongly subquadratic time for $k,m = \Theta(\log n)$ unless the Strong Exponential Time Hypothesis fails.Comment: Accepted to SPIRE 201

A Tool for Integer Homology Computation: Lambda-At Model

In this paper, we formalize the notion of lambda-AT-model (where $\lambda$ is a non-null integer) for a given chain complex, which allows the computation of homological information in the integer domain avoiding using the Smith Normal Form of the boundary matrices. We present an algorithm for computing such a model, obtaining Betti numbers, the prime numbers p involved in the invariant factors of the torsion subgroup of homology, the amount of invariant factors that are a power of p and a set of representative cycles of generators of homology mod p, for each p. Moreover, we establish the minimum valid lambda for such a construction, what cuts down the computational costs related to the torsion subgroup. The tools described here are useful to determine topological information of nD structured objects such as simplicial, cubical or simploidal complexes and are applicable to extract such an information from digital pictures.Comment: Journal Image and Vision Computing, Volume 27 Issue 7, June, 200

Transcriptome map of mouse isochores

Background: The availability of fully sequenced genomes and the implementation of transcriptome technologies have increased the studies investigating the expression profiles for a variety of tissues, conditions, and species. In this study, using RNA-seq data for three distinct tissues (brain, liver, and muscle), we investigate how base composition affects mammalian gene expression, an issue of prime practical and evolutionary interest.Results: We present the transcriptome map of the mouse isochores (DNA segments with a fairly homogeneous base composition) for the three different tissues and the effects of isochores' base composition on their expression activity. Our analyses also cover the relations between the genes' expression activity and their localization in the isochore families.Conclusions: This study is the first where next-generation sequencing data are used to associate the effects of both genomic and genic compositional properties to their corresponding expression activity. Our findings confirm previous results, and further support the existence of a relationship between isochores and gene expression. This relationship corroborates that isochores are primarily a product of evolutionary adaptation rather than a simple by-product of neutral evolutionary processes.</p

Polaron Variational Methods In The Particle Representation Of Field Theory : II. Numerical Results For The Propagator

For the scalar Wick-Cutkosky model in the particle representation we perform a similar variational calculation for the 2-point function as was done by Feynman for the polaron problem. We employ a quadratic nonlocal trial action with a retardation function for which several ans\"atze are used. The variational parameters are determined by minimizing the variational function and in the most general case the nonlinear variational equations are solved numerically. We obtain the residue at the pole, study analytically and numerically the instability of the model at larger coupling constants and calculate the width of the dressed particle.Comment: 25 pages standard LaTeX, 9 uuencoded postscript figures embedded with psfig.st

The Robustness of Quintessence

Recent observations seem to suggest that our Universe is accelerating implying that it is dominated by a fluid whose equation of state is negative. Quintessence is a possible explanation. In particular, the concept of tracking solutions permits to adress the fine-tuning and coincidence problems. We study this proposal in the simplest case of an inverse power potential and investigate its robustness to corrections. We show that quintessence is not affected by the one-loop quantum corrections. In the supersymmetric case where the quintessential potential is motivated by non-perturbative effects in gauge theories, we consider the curvature effects and the K\"ahler corrections. We find that the curvature effects are negligible while the K\"ahler corrections modify the early evolution of the quintessence field. Finally we study the supergravity corrections and show that they must be taken into account as $Q\approx m_{\rm Pl}$ at small red-shifts. We discuss simple supergravity models exhibiting the quintessential behaviour. In particular, we propose a model where the scalar potential is given by $V(Q)=\frac{\Lambda^{4+\alpha }}{Q^{\alpha}}e^{\frac{\kappa}{2}Q^2}$. We argue that the fine-tuning problem can be overcome if $\alpha \ge 11$. This model leads to $\omega_Q\approx -0.82$ for $\Omega_{\rm m}\approx 0.3$ which is in good agreement with the presently available data.Comment: 16 pages, 7 figure

Effect of the counter cation on the third order nonlinearity in anionic Au dithiolene complexes

In this work, we present the third order nonlinear optical investigation of two gold complexes, which differ by the nature of the counter cations. The impact of the different design in the architecture through a set of hydrogen bonds in the case of Au-Mel of the systems on the nonlinearity has been studied by means of the Z-scan setup under 532 nm, 30 ps laser excitation, allowing for the determination of the nonlinear absorption and refraction of the samples. Significant modification of the nonlinear optical response between the two metal complexes has been found suggesting a clear effect of the counter cation

Path integral evaluation of the one-loop effective potential in field theory of diffusion-limited reactions

The well-established effective action and effective potential framework from the quantum field theory domain is adapted and successfully applied to classical field theories of the Doi and Peliti type for diffusion controlled reactions. Through a number of benchmark examples, we show that the direct calculation of the effective potential in fixed space dimension $d=2$ to one-loop order reduces to a small set of simple elementary functions, irrespective of the microscopic details of the specific model. Thus the technique, which allows one to obtain with little additional effort, the potentials for a wide variety of different models, represents an important alternative to the standard model dependent diagram-based calculations. The renormalized effective potential, effective equations of motion and the associated renormalization group equations are computed in $d=2$ spatial dimensions for a number of single species field theories of increasing complexity.Comment: Plain LaTEX2e, 32 pages and three figures. Submitted to Journal of Statistical Physic