Xylem plasticity in Pinus pinaster and Quercus ilex growing at sites with different water availability in the Mediterranean region: relations between Intra-Annual Density Fluctuations and environmental conditions.

Fluctuations in climatic conditions during the growing season are recorded in Mediterranean tree-rings and often result in intra-annual density fluctuations (IADFs). Dendroecology and quantitative wood anatomy analyses were used to characterize the relations between the variability of IADF traits and climatic drivers in Pinus pinaster Aiton and Quercus ilex L. growing at sites with different water availability on the Elba island in Central Italy. Our results showed that both species present high xylem plasticity resulting in the formation of L-type IADFs (L-IADFs), consisting of earlywood-like cells in latewood. The occurrence of such IADFs was linked to rain events following periods of summer drought. The formation of L-IADFs in both species increased the hydraulic conductivity late in the growing season, due to their larger lumen area in comparison to "true latewood". The two species expressed greater similarity under arid conditions, as unfavorable climates constrained trait variation. Wood density, measured as the percentage of cell walls over total xylem area, IADF frequency, as well as conduit lumen area and vessel frequency, specifically in the hardwood species, proved to be efficient proxies to encode climate signals recorded in the xylem. The response of these anatomical traits to climatic variations was found to be species- and site-specific

Building up the inhibitory synapses

2nonenoneCherubini E; Zacchi PCherubini, E; Zacchi,

Excised acoustic black holes: the scattering problem in the time domain

The scattering process of a dynamic perturbation impinging on a draining-tub model of an acoustic black hole is numerically solved in the time domain. Analogies with real black holes of General Relativity are explored by using recently developed mathematical tools involving finite elements methods, excision techniques, and constrained evolution schemes for strongly hyperbolic systems. In particular it is shown that superradiant scattering of a quasi-monochromatic wavepacket can produce strong amplification of the signal, offering the possibility of a significant extraction of rotational energy at suitable values of the angular frequency of the vortex and of the central frequency of the wavepacket. The results show that theoretical tools recently developed for gravitational waves can be brought to fruition in the study of other problems in which strong anisotropies are present.Comment: 8 pages, 9 figure

Prion expression is activated by Adenovirus 5 infection and affects the adenoviral cycle in human cells

The prion protein is a cell surface glycoprotein whose physiological role remains elusive, while its implication in transmissible spongiform encephalopathies (TSEs) has been demonstrated. Multiple interactions between the prion protein and viruses have been described: viruses can act as co-factors in TSEs and life cycles of different viruses have been found to be controlled by prion modulation. We present data showing that human Adenovirus 5 induces prion expression. Inactivated Adenovirus did not alter prion transcription, while variants encoding for early products did, suggesting that the prion is stimulated by an early adenoviral function. Down-regulation of the prion through RNA interference showed that the prion controls adenovirus replication and expression. These data suggest that the prion protein could play a role in the defense strategy mounted by the host during viral infection, in a cell autonomous manner. These results have implications for the study of the prion protein and of associated TSEs

Electrocardiogram of the Mixmaster Universe

The Mixmaster dynamics is revisited in a new light as revealing a series of transitions in the complex scale invariant scalar invariant of the Weyl curvature tensor best represented by the speciality index $\mathcal{S}$, which gives a 4-dimensional measure of the evolution of the spacetime independent of all the 3-dimensional gauge-dependent variables except for the time used to parametrize it. Its graph versus time characterized by correlated isolated pulses in its real and imaginary parts corresponding to curvature wall collisions serves as a sort of electrocardiogram of the Mixmaster universe, with each such pulse pair arising from a single circuit or ``complex pulse'' around the origin in the complex plane. These pulses in the speciality index and their limiting points on the real axis seem to invariantly characterize some of the so called spike solutions in inhomogeneous cosmology and should play an important role as a gauge invariant lens through which to view current investigations of inhomogeneous Mixmaster dynamics.Comment: version 3: 20 pages iopart style, 19 eps figure files for 8 latex figures; added example of a transient true spike to contrast with the permanent true spike example from the Lim family of true spike solutions; remarks in introduction and conclusion adjusted and toned down; minor adjustments to the remaining tex

Optimal design of isolated mini-grids with deterministic methods: matching predictive operating strategies with low computational requirements

The lack of electricity access is increasingly concentrated in rural areas of developing countries, in which mini-grids are often a suitable solution; however, given the high risks, it is crucial to minimize costs. This paper aims at analyzing existing methodologies for the optimal design of mini-grids combined with different operating strategies. Typical system operations, like the load-following (LFS) and cycle charging (CCS) strategies, are compared with the more demanding predictive strategies based on Mixed-Integer Linear Programming (MILP). The problem is formulated and solved with Particle Swarm Optimization (PSO), so to simulate traditional and predictive operating strategies. Two reformulations based on the proposed Search Space Update are also detailed and compared with the so-called one-shot MILP model, which is able to con-jointly optimize both the design and the operation of the system, in order to reduce computational requirements with the predictive strategy. The results, tailored with data from a rural mini-grid in Kenya, highlight that heuristic methodologies can perform better than the traditional MILP approach, both in terms of optimality and computational time, especially when advanced operating strategies are considered. Conventional operating strategies (LFS or CCS) appear to be sub-optimal, but require very little computational requirements, which makes them suitable for preliminary designs

Evidence Evaluation: Measure Z Corresponds to Human Utility Judgments Better than Measure L and Optimal-Experimental-Design Models

Evidence evaluation is a crucial process in many human activities, spanning from medical diagnosis to impression formation. The present experiments investigated which, if any, normative model best conforms to people’s intuition about the value of the obtained evidence. Psychologists, epistemologists, and philosophers of science have proposed several models to account for people’s intuition about the utility of the obtained evidence with respect either to a focal hypothesis or to a constellation of hypotheses. We pitted against each other the so called optimal-experimental-design models (i.e., Bayesian diagnosticity, log10 diagnosticity, information gain, Kullback-Leibler distance, probability gain, and impact) and measures L and Z to compare their ability to describe humans’ intuition about the value of the obtained evidence. Participants received words-and-numbers scenarios concerning two hypotheses and binary features. They were asked to evaluate the utility of “yes” and “no” answers to questions about some features possessed in different proportions (i.e., the likelihoods) by two types of extraterrestrial creatures (corresponding to two mutually exclusive and exhaustive hypotheses). Participants evaluated either how an answer was helpful or how an answer decreased/increased their beliefs with respect either to a single hypothesis or to both hypotheses. We fitted mixed-effects models and we used the Akaike information criterion (AIC) and the Bayesian information criterion (BIC) values to compare the competing models of the value of the obtained evidence. Overall, the experiments showed that measure Z was the best-fitting model of participants’ judgments of the value of obtained answers. We discussed the implications for the human hypothesis-evaluation process

Superradiance from BEC vortices: a numerical study

The scattering of sound wave perturbations from vortex excitations of Bose-Einstein condensates(BEC) is investigated by numerical integration of the associated Klein-Gordon equation. It is found that, at sufficiently high angular speeds, sound wave-packets can extract a sizeable fraction of the vortex energy through a mechanism of superradiant scattering. It is conjectured that this superradiant regime may be detectable in BEC experiments.Comment: 4 pages, 4 figure

Testing the Gaussian Copula Hypothesis for Financial Assets Dependences

Using one of the key property of copulas that they remain invariant under an arbitrary monotonous change of variable, we investigate the null hypothesis that the dependence between financial assets can be modeled by the Gaussian copula. We find that most pairs of currencies and pairs of major stocks are compatible with the Gaussian copula hypothesis, while this hypothesis can be rejected for the dependence between pairs of commodities (metals). Notwithstanding the apparent qualification of the Gaussian copula hypothesis for most of the currencies and the stocks, a non-Gaussian copula, such as the Student's copula, cannot be rejected if it has sufficiently many ``degrees of freedom''. As a consequence, it may be very dangerous to embrace blindly the Gaussian copula hypothesis, especially when the correlation coefficient between the pair of asset is too high as the tail dependence neglected by the Gaussian copula can be as large as 0.6, i.e., three out five extreme events which occur in unison are missed.Comment: Latex document of 43 pages including 14 eps figure