66 research outputs found
Determinants of Rotavirus Transmission A Lag Nonlinear Time Series Analysis
Development and application of statistical models for medical scientific researc
Determinants of Rotavirus Transmission A Lag Nonlinear Time Series Analysis
Development and application of statistical models for medical scientific researc
Updated cost-effectiveness and risk-benefit analysis of two infant rotavirus vaccination strategies in a high-income, low-endemic setting.
Since 2013, a biennial rotavirus pattern has emerged in the Netherlands with alternating high and low endemic years and a nearly 50% reduction in rotavirus hospitalization rates overall, while infant rotavirus vaccination has remained below 1% throughout. As the rotavirus vaccination cost-effectiveness and risk-benefit ratio in high-income settings is highly influenced by the total rotavirus disease burden, we re-evaluated two infant vaccination strategies, taking into account this recent change in rotavirus epidemiology
Роль православної церкви у формуванні та функціонуванні політичної системи України в 90-і роки ХХ ст.
У статті зроблено спробу аналізу місця та ролі православної церкви у процесах формування та
функціонування політичної системи України у 90-і роки ХХ ст. Доведено, що українські православні церкви
відігравали значну роль у політичному житті країни, не тільки агітуючи віруючих за певну політичну силу, а й
балотуючи своїх представників до місцевих органів влади. Українські політики використовували церкву
заради досягнення власних цілей, що ще більше загострювало міжконфесійні взаємини і посилювало
політизацію церковного життя.В статье сделана попытка анализа места и роли православной церкви в процессе формирования и
функционирования политической системы Украины в 90-е годы ХХ ст. Доказано, что украинские
православные церкви играли значительную роль в политической жизни страны, не только агитируя
верующих за определенную политическую силу, но и баллотируя своих представителей в местные
органы власти. Украинские политики использовали церковь ради достижения собственных целей, что
еще больше обостряло межконфессиональные отношения и усиливало политизацию церковной жизни.In the article the attempt of analysis of place and role of orthodox church in the process of forming and
functioning of the political system of Ukraine in the 90
th
ys of the XX ct is done. It is proved, that the Ukrainian
orthodox churches acted considerable part in the political life of country, not only agitating believers for definite
political force, but also voting the representatives in local authorities. The Ukrainian politicians used a church for
achievement of own purposes, that yet more intensified the interconfession relations reinforced the political
impact on the church life
SARS-CoV-2 incidence in secondary schools; the role of national and school-initiated COVID-19 measures
Two Randomized Controlled Trials of Bacillus Calmette-Guerin Vaccination to reduce absenteeism among health care workers and hospital admission by elderly persons during the COVID-19 pandemic: A structured summary of the study protocols for two randomised controlled trials (vol 21, 481, 2020)
SARS-CoV-2 incidence in secondary schools: the role of national and school-initiated COVID-19 measures
INTRODUCTION: Our aim was to gain insight into the effect of COVID-19 measures on SARS-CoV-2 incidence in secondary schools and the association with classroom CO 2 concentration and airborne contamination. METHODS: Between October 2020-June 2021, 18 schools weekly reported SARS-CoV-2 incidence and completed surveys on school-initiated COVID-19 measures (e.g. improving hygiene or minimizing contacts). CO 2 was measured in occupied classrooms twice, and SARS-CoV-2 air contamination longitudinally using electrostatic dust collectors (EDC) and analyzed using RT-qPCR. National COVID-19 policy measures varied during pre-lockdown, lockdown and post-lockdown periods. During the entire study, schools were recommended to improve ventilation. SARS-CoV-2 incidence rate ratios (IRR) were estimated by Generalized Estimating Equation (GEE) models. RESULTS: During 18 weeks follow-up (range: 10-22) SARS-CoV-2 school-incidence decreased during national lockdown (adjusted IRR: 0.41, 95%CI: 0.21-0.80) and post-lockdown (IRR: 0.60, 0.39-0.93) compared to pre-lockdown. School-initiated COVID-19 measures had no additional effect. Pre-lockdown, IRRs per 10% increase in time CO 2 exceeded 400, 550 and 800 ppm above outdoor level respectively, were 1.08 (1.00-1.16), 1.10 (1.02-1.19), and 1.08 (0.95-1.22). Post-lockdown, CO 2-concentrations were considerably lower and not associated with SARS-CoV-2 incidence. No SARS-CoV-2 RNA was detected in any of the EDC samples. CONCLUSION: During a period with low SARS-CoV-2 population immunity and increased attention to ventilation, with CO 2 levels most of the time below acceptable thresholds, only the national policy during and post-lockdown of reduced class-occupancy, stringent quarantine, and contact testing reduced SARS-CoV-2 incidence in Dutch secondary schools. Widespread SARS-CoV-2 air contamination could not be demonstrated in schools under the prevailing conditions during the study
SARS-CoV-2 outbreaks in secondary school settings in the Netherlands during fall 2020: silent circulation
BACKGROUND: In fall 2020 when schools in the Netherlands operated under a limited set of COVID-19 measures, we conducted outbreaks studies in four secondary schools to gain insight in the level of school transmission and the role of SARS-CoV-2 transmission via air and surfaces. METHODS: Outbreak studies were performed between 11 November and 15 December 2020 when the wild-type variant of SARS-CoV-2 was dominant. Clusters of SARS-CoV-2 infections within schools were identified through a prospective school surveillance study. All school contacts of cluster cases, irrespective of symptoms, were invited for PCR testing twice within 48 h and 4-7 days later. Combined NTS and saliva samples were collected at each time point along with data on recent exposure and symptoms. Surface and active air samples were collected in the school environment. All samples were PCR-tested and sequenced when possible. RESULTS: Out of 263 sampled school contacts, 24 tested SARS-CoV-2 positive (secondary attack rate 9.1%), of which 62% remained asymptomatic and 42% had a weakly positive test result. Phylogenetic analysis on 12 subjects from 2 schools indicated a cluster of 8 and 2 secondary cases, respectively, but also other distinct strains within outbreaks. Of 51 collected air and 53 surface samples, none were SARS-CoV-2 positive. CONCLUSION: Our study confirmed within school SARS-CoV-2 transmission and substantial silent circulation, but also multiple introductions in some cases. Absence of air or surface contamination suggests environmental contamination is not widespread during school outbreaks
Infecção pulmonar fatal por Lagochilascaris sp., provavelmente Lagochilascaris minor Leiper, 1909
Genotyping of gastroenteric viruses in hospitalised children: first report of norovirus GII.21 in Brazil
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