El lugar de la mente : sobre la capilla Sogn Benedetg de Peter Zumthor en Sumvitg = The place of the mind : On Peter Zumthor’s Sogn Benedetg Chapel in Sumvitg

La Capilla de Sogn Benedetg en Sumvitg, parte de la obra temprana de Peter Zumthor, condensa aspectos de sus ideas, de su forma de proyectar y construir, que aún hoy siguen vigentes en él. Los recuerdos de infancia cimientan su enfoque de la arquitectura, en el que trata de reunir trazas de la vida cotidiana, sensible al lugar y utilizando materiales tratados de un modo preciso que bajo la luz adquieren su presencia. Con un lenguaje táctil y tectónico, desde una aproximación fenomenológica, persigue compartir una experiencia multisensorial, englobando percepciones complementarias que trascienden la geometría visual. Como Kahn, se apoya en el pensamiento de Heidegger, y se inspira en la pequeña cabaña que el filósofo habitaba en la Selva Negra, así como en la arquitectura religiosa de Rudolf Schwarz, cuya huella puede apreciarse tanto en el edificio como en los objetos que se encuentran en él. La tensión que genera entre interior y exterior mantiene despiertos los sentidos del visitante, a la vez que las características de la capilla enlazan con un regionalismo integrador que no se aparta de las formas abstractas contemporáneas. ----------ABSTRACT---------- Sogn Benedetg Chapel in Sumvitg, part of the early work of Peter Zumthor, condenses aspects of his ideas and his way of designing and building, which still remain valid today. Remembrances of childhood lay the foundation for his focus to architecture, which involves the collection of daily life traces, sensitive to the place and using materials treated in a precise manner, acquiring their presence under the light. With a tactile and tectonic language, from a phenomenological approach, he seeks to share a multi-sensory experience, encompassing complementary perceptions that transcend the visual geometry. As Kahn does, he relies on Heidegger’s thinking and is inspired by the little hut that the philosopher inhabited in the Black Forest, as well as by Rudolf Schwarz’s religious architecture, whose imprint can be appreciated in both the building and the objects encountered within it. The tension generated between interior and exterior keeps awake the senses of the visitor, while the characteristics of the chapel connect with an integrative regionalism that does not exclude contemporary abstract forms

Elaboración de un plan de marketing para la Asociación Emprendedores 21 de Abril de la ciudad de Riobamba, provincia de Chimborazo

La realización del Plan de Marketing para la Asociación de emprendedores 21 de Abril de la ciudad de Riobamba, provincia del Chimborazo tiene como objetivo principal posicionar los productos de la empresa. Para lograr un análisis ajustado a la realidad de la organización se aplico una metodologia de enfoque mixto, es decir cualitativo basado en las características de la asociación, como cuantitativo al referirse a los resultados estadísticos obtenidos de las encuestas aplicadas a personas de la ciudad, también se aplicaron herramientas de planificación estratégica tales como análisis del macro y micro entorno, matriz FODA y análisis SERVQUAL que determinaron la situación actual de la empresa la que presenta un posicionamiento menor al 20%, imagen corporativa no definida y una cartera de productos reducida. Como desenlace del trabajo la empresa requiere estrategias de posicionamiento basadas en el estudio de mercado, haciendo enfacis en la imagen corporativa y diversificacion de mercados, además de publicidad web. La realización del plan de marketing para la empresa, se convierte en una herramienta necesaria de gestión, para el posicionamiento de los productos por lo tanto se recomienda la implementación.This research work was carried out with the main objective of possessing the company's products; through a Marketing Plan from April 21 Entrepreneurs Association in Riobamba city, Chimborazo province. For achieving an analysis adjusted to reality organization, it was applied a methodology of mixed approach, that is to qualitative based on the characteristics of the association, quantitative when referring to the statistical results obtained from surveys applied to people in the city. It applied strategic planning tools such as macro and microenvironment analysis, matrix of internal and external analyzes (SWOT) matrix and survey addressed to the internal client (SERVQUAL) analysis, which determined the current situation of the company with a positioning less than 20%, undefined corporate image not defined and a reduced product portfolio. As a result, the company requires positioning strategies based on market research, emphasizing the corporate image and market diversification, as well as web advertising strategies. The realization of marketing plan for the company becomes a necessary tool of management, for the positioning of the products, therefore the implementation is recommended

Physicochemical evaluation of personal care products Ddeveloped with Chondrus crispus fractions processed by ecofriendly methodologies

Novel personal care products are necessary to cope with the growing market demand for sustainable green products. In this context, this work deals with the formulation and fundamental physicochemical and rheological characterization of different natural personal care products using bioactive fractions from Chondrus crispus red macroalgae extracted under optimized green conditions. Body milks, body oils and shampoos were supplemented with soluble extracts with antioxidant features recovered after hydrothermal (200 °C) and microwave (170 °C)- and ultrasound (80 °C)-assisted extraction of the red macroalgae used as raw material. Formulated products were also compared with those prepared using (±)-α-tocopherol and butylhydroxytoluene standards. Body scrubs were formulated with the remaining solids (<2.25 %) after microwave hydrodiffusion and gravidity treatment of the macroalgae. Results indicated that selected extracts provided personal care products with similar or even better physicochemical, color and viscous features than those supplemented with (±)-α-tocopherol or butylhydroxytoluene commercial antioxidants. Rheological profiles indicated that it is possible to develop personal care products with adequate viscous behavior (102–105 mPa s, at 1 s−1), comparable with their synthetic counterparts. To conclude, the addition of antioxidant extracts led to lower apparent viscosity values suggesting an advantage from the skin applicability point of view, jointly with the absence of both the hysteresis phenomenon and water syneresis of the proposed formulations.Xunta de Galicia | Ref. ED431F 2020/01Ministerio de Ciencia, Innovación y Universidades | Ref. RTI2018-096376-B-I00Ministerio de Ciencia, Innovación y Universidades | Ref. RYC2018-024454-

Association Between Preschoolers' Specific Fine (But Not Gross) Motor Skills and Later Academic Competencies: Educational Implications

Motor development is an inseparable component of cognitive development. So, to develop the mind, it is necessary to work the body. Therefore, Early Childhood Education curricula and the scientific literature emphasize the need to promote the development of motor skills during the 1st years of life. These skills are necessary for learning and subsequent academic performance. However, studies frequently offer only a partial view of these relationships. Few works have analyzed the specific relationships between different components of preschool gross and fine motor skills and subsequent performance on different academic competencies. Further, they present discrepant results. The aim of this study was to determinate which specific components of gross and fine motor skills assessed in Spanish students during the final year of Early Childhood Education (5 to 6-year-olds) were associated with different academic competencies assessed in the following academic year, when the students were in their 1st year of Primary Education. The final sample consisted of 38 Spanish students, aged 5. A mixed methods approach was used. It consisted of systematic observation to assess specific components of gross and fine motor skills when children were in the Early Childhood Education period, and selective methodology to evaluate their academic competencies (specifically in literacy and mathematics and overall), 1 year later, once in Primary Education. Multiple linear regression models were constructed using the computing language R to examine the association between motor skills and academic competencies. The results indicated that only the components of fine motor skills showed associations with academic competencies. The pattern of association varied when literacy and mathematics competencies were specifically and individually assessed and when overall academic competency was considered. The two assessed fine motor skills (Coordination and Integration) were associated with literacy competency (β = 0.344, p = 0.025; β = 0.349, p = 0.024, respectively) and overall academic competency (β = 0.267, p = 0.065; β = 0.493, p = 0.001, respectively). However, only Integration was associated with mathematics competency (β = 0.476, p = 0.002). The 'Discussion' section focuses on the educational implications of these results and future research. It highlights the importance of early assessment of fine motor skills to identify students likely to present inadequate subsequent academic performance and the need to apply instruction and interventions tailored to the specific needs of each child

Early environmental and biological influences on preschool motor skills: implications for early childhood care and education

Early motor skills underpin the more complex and specialized movements required for physical activity. Therefore, the design of interventions that enhance higher levels of early motor skills may encourage subsequent participation in physical activity. To do so, it is necessary to determine the influence of certain factors (some of which appear very early) on early motor skills. The objective of this study was to examine the influence of some very early environmental variables (delivery mode, feeding type during the first 4 months of life) and some biological variables (sex and age in months) on preschool motor skills, considered both globally and specifically. The sample was composed by 43 preschool students aged 5–6 years. The participant's parents completed an ad hoc questionnaire, reporting on delivery mode, feeding type, sex, and age in months. The children's motor skills were assessed using observational methodology in the school setting, while the children participated in their regular motor skills sessions. A Nomothetic/Punctual/Multidimensional observational design was used. Results revealed that certain preschool motor skills were specifically influenced by delivery mode, feeding type, sex, and age. Children born by vaginal delivery showed higher scores than children born via C-section in throwing (p = 0.000; d = 0.63); total control of objects (p = 0.004; d = 0.97); total gross motor skills (p = 0.005; d = 0.95); and total motor skills (p = 0.002; d = 1.04). Children who were exclusively breastfed outperformed those who were formula-fed in throwing (p = 0.016; d = 0.75); visual-motor integration (p = 0.005; d = 0.94); total control of objects (p = 0.002; d = 1.02); total gross motor skills (p = 0.023; d = 0.82); and total motor skills (p = 0.042; d = 0.74). Boys outperformed girls in throwing (p = 0.041; d = 0.74) and total control of objects (p = 0.024; d = 0.63); while the opposite occurred in static balance (p = 0.000; d = 1.2); visual-motor coordination (p = 0.020; d = 0.79); and total fine motor skills (p = 0.032; d = 0.72). Older children (aged 69–74 months) obtained higher scores than younger ones (aged 63–68 months) in dynamic balance (p = 0.030; d = 0.66); visual-motor integration (p = 0.034; d = 0.63); and total balance (p = 0.013; d = 0.75). Implications for early childhood care and education are discussed since this is a critical period for motor skill development and learning

Effect of the horizontal aspect ratio on thermocapillary convection stability in annular pool with surface heat dissipation

A linear stability analysis of the thermoconvective problem of a thin liquid film contained in an annular domain has been conducted. The influence of the horizontal aspect ratio on the solution has been considered by keeping a fixed external wall while the internal radius of the annular domain was modified. The parameter used in the study, Gammah, has been defined as the ratio of the internal radius to the domain depth. The other control parameter of the study is the Prandtl number ranging from 0.7 to 50, i.e. characteristic of fluids as air to butanol. The study has been performed for different Bond (Bo) regimes ranging from 0.0 for surface tension dominated flows to 67 for buoyancy dominated ones. Three different kind of bifurcations are found in the plane for large Bonds, while for low Bonds only two of them appear. In the case of pure buoyancy or surface tension flows, for every Gammah there exists a Prandtl number such that oscillatory and stationary coexist in a co-dimension two bifurcation point. These transitions show a strong dependency with the Bond number. Indeed, the lower transition disappears for low Bo and the upper one disappears with intermediate Bo values. Furthermore, there is a non-linear dependency of the number of structures of the growing bifurcation with Gammah. These co-dimension two lines show a strong dependency with Bo. Firstly, looking at the frontier between HWI and LR regions, for large Bo numbers, Pr increases with Gammah, while for low Bo the trend is reversed. Additionally, this transition only appears in the extreme Bo cases, for the central values of the considered, no transition is found. Similarly, the second transition found only appears for Bo larger than 30.SH and MJPQ work have been supported by project RTI2018-102256-BI00 of Mineco/FEDER. PF work has been partially supported by the Spain's National Research and Development Plan (Project ESP2016-75887) and by the CHEOPS project (Grant Agreement 730135). This work was supported by a generous grant of computer time from the supercomputing center of the UPV.Publicad

Estudio comparativo de técnicas para la detección automática de patrones interictales en señal de EEG de pacientes epilépticos

La epilepsia es una afección neurológica grave que condiciona la calidad de vida de las personas que sufren de ella. Una de las labores de los neurólogos y neurofisiólogos consiste en revisar los Video-EEG de los pacientes epilépticos para analizar la semiología de las crisis epilépticas así como el patrón EEG crítico y los periodos intercríticos que se caracterizan por la aparición de descargas epileptiformes paroxísticas con frecuencia variable. Los registros pueden durar desde minutos hasta días, y la tarea de análisis del EEG por parte del especialista resulta lenta y agotadora. Frente esta problemática es deseable conseguir un programa de detección de eventos relevantes en el EEG que permita acortar el tiempo de análisis de los registros. El presente artículo se centra en definir un primer paso hacia el desarrollo de una aplicación que permita la detección de descargas epileptiformes interictales (DEI) de tipo punta en señales EEG de pacientes epilépticos. El objetivo es realizar un estudio comparativo entre dos métodos de detección: Filtros adaptados y la Transformada Wavelet Continua (CWT) evaluando los resultados con el parámetro de área bajo la curva (AUC) y la curva ROC. Los resultados muestran que el uso de la CWT es más eficiente a la hora de detectar puntas dentro de señales EEG que el Filtro adaptado. A pesar de los buenos resultados obtenidos, es necesario verificar ambos métodos con nuevos registros de datos y mejorar los procesos de automatización para conseguir un programa de detección fiable

Capillary electrophoresis-mass spectrometry metabolic fingerprinting of green and roasted coffee

The aim of this work was to develop a capillary electrophoresis-mass spectrometry (CE-ESI-QToF-MS) method to carry out the metabolic fingerprinting of green and roasted coffee samples (Arabica variety). To evaluate changes in the metabolic profiles of coffee occurring along the roasting process, green coffee beans were submitted to different roasting degrees. The effect of different parameters concerning the electrophoretic separation (background electrolyte, temperature, voltage, and injection time), the MS detection (temperature and flow of drying gas, sheath gas of jet stream temperature, and capillary, fragmentator, nozzle, skimmer, and octapole voltages) and the sheath liquid (composition and flow rate) was studied to achieve an adequate separation and to obtain the largest number of molecular features. The analyses were carried out in positive ESI mode allowing to detect highly polar cationic metabolites present in coffee beans. Non-supervised and supervised multivariate analyses were performed showing a good discrimination among the different coffee groups. Those features having a high variable importance in the projection values on supervised analyses were selected as significant metabolites for their identification. Thus, 13 compounds were proposed as potential markers of the coffee roasting process, being 7 of them tentatively identified and 2 of them unequivocally identified. Different families of compounds such as pyridines, pyrroles, betaines, or indoles could be pointed out as markers of the coffee roasting process. (C) 2019 Elsevier B.V. All rights reserved

Untargeted HILIC-MS-based metabolomics approach to evaluate coffee roasting process: contributing to an integrated metabolomics multiplatform

An untargeted metabolomics strategy using hydrophilic interaction chromatography-mass spectrometry (HILIC-MS) was developed in this work enabling the study of the coffee roasting process. Green coffee beans and coffee beans submitted to three different roasting degrees (light, medium, and strong) were analyzed. Chromatographic separation was carried out using water containing 10 mM ammonium formate with 0.2 % formic acid (mobile phase A) and acetonitrile containing 10mM ammonium formate with 0.2% formic acid (mobile phase B). A total of 93 molecular features were considered from which 31 were chosen as the most statistically significant using variable in the projection values. 13 metabolites were tentatively identified as potential biomarkers of the coffee roasting process using this metabolomic platform. Results obtained in this work were complementary to those achieved using orthogonal techniques such as reversed-phase liquid chromatography-mass spectrometry (RPLC-MS) and capillary electrophoresis-mass spectrometry (CE-MS) since only one metabolite was found to be common between HILIC-MS and RPLC-MS platforms (caffeoylshikimic acid isomer) and other between HILIC-MS and CE-MS platforms (choline). On the basis of these results, an untargeted metabolomics multiplatform is proposed in this work based on the integration of the three orthogonal techniques as a powerful tool to expand the coverage of the roasted coffee metabolome