2,456 research outputs found

    A collaborative company commited to ethics and labor conditions

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    Estudia2 es un proyecto empresarial joven y colaborativo, con menos de cinco años de andadura, que ha nacido con la intención de ser una plataforma internacional de encuentro entre personas para compartir conocimientos, una plataforma de E-learning llevada a cabo con la conjunción de un diseño propio y el empleo de una serie de herramientas TIC de acceso libre. Una de las máximas más importantes con las que ha nacido esta empresa es el respeto absoluto por unos valores éticos basados en el cumplimiento de las condiciones laborales de los trabajadores, los derechos de autoría de los creadores de contenidos y la privacidad de los datos de los usuarios.Estudia2 is a young and collaborative business project, with less than five years operating, that was born with the goal of being an international platform for connecting people to share knowledge. An E-learning platform developed with the conjunction of an own design and the use of a mixture of free access ICT tools. One of the most important ideas which this project has been born in, is the absolute respect to several ethical values based on the fulfillment of the workers’ labor conditions, the intellectual property rights of the content creators and the privacy of the user data.Ministerio de Economía y Competitividad CSO2016-78386-

    Problemas antiplanos de mecánica de la fractura en materiales anisótropos

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    XV Congreso nacional de Ingeniería Mecánica, celebrado en Cádiz en 2002Se presenta la formulación mixta del Método de los Elementos de Contorno (MEC) para problemas de mecánica de fractura antiplanos en medios anisótropos. Se implementan las ecuaciones integrales (El) en desplazamientos y en tracciones. Las integrales hipersingulares asociadas a la El en tracciones se evalúan mediante un cambio de variable que permite su descomposición en integrales singulares con solución analítica conocida e integrales regulares de fácil integración numérica. Se consideran las soluciones fundamentales para plano completo y para semiplano.Ministerio de Ciencia y Tecnología DPI2000-12 l 7-C02-0

    Enfermeria prática clínica no tratamento de género da violencia

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    La violencia contra las mujeres es un fenómeno que ocurre en todos los países, clases sociales y ámbitos de la sociedad. Según la definición de la ONU, la violencia de género (VG) es “cualquier acto o intención que origina daño o sufrimiento físico, sexual o psicológico a las mujeres, incluyendo las amenazas de dichos actos, la coerción o privación arbitraria de libertad, ya sea en la vida pública o privada” Las necesidades específicas de estas mujeres son multidimensionales, por lo que se requieren intervenciones sanitarias que tengan en cuenta los aspectos biológicos, psicológicos y sociales. Para ello es necesaria la implicación activa de todo el personal de los servicios sanitarios desde un modelo de atención integral. El estudio tiene como objetivo conocer la base de actuación enfermera para el abordaje de la violencia de género. La metodología usada para este estudio es de investigación cualitativo-descriptiva que se inicia con una búsqueda bibliográfica y continúa con el análisis hermenéutico de los documentos encontrados. Las conclusiones de este estudio versan sobre la formación de las enfermeras en el abordaje de la violencia de género, así como los puntos fuertes y debilidades al respecto.Violence against women is a phenomenon that occurs in all countries, social classes and sectors of society. According to the UN definition, gender-based violence (GBV) is “any act or intention that causes harm or physical, sexual or psychological suffering to women, including threats of such acts, coercion or arbitrary deprivation of liberty, and whether in public or private life “the specific needs of these women are multidimensional, so health interventions that take into account the biological, psychological and social aspects are required. This requires the active involvement of all staff in health services is required from a model of comprehensive care. The study aims to determine the basis of nurse for addressing GBV action. The methodology used for this study is qualitative-descriptive research begins with a literature search and continues with the hermeneutic analysis of the documents found. The findings of this study relate to the training of nurses in addressing gender-based violence, as well as the strengths and weaknesses in this regard.Violência contra a mulher é um fenômeno que ocorre em todos os países, classes sociais e setores da sociedade. De acordo com a definição da ONU, a violência baseada no género (VBG) é “qualquer ato ou intenção que causa dano ou física, sofrimento sexual ou psicológico à mulher, inclusive ameaças de tais atos, coerção ou privação arbitrária de liberdade, e seja na vida pública ou privada “as necessidades específicas dessas mulheres são, por assim intervenções multidimensionais de saúde que levem em conta os aspectos biológicos, psicológicos e sociais são necessários. Isso requer a participação activa de todos os funcionários em serviços de saúde é exigido de um modelo de atenção integral. O estudo tem como objetivo determinar a base de enfermeira para tratar de ação VBG. A metodologia utilizada para este estudo é uma pesquisa qualitativa-descritiva começa com uma pesquisa bibliográfica e continua com a análise hermenêutica dos documentos encontrados. As conclusões deste estudo referem-se à formação de enfermeiros no enfrentamento da violência de gênero, bem como os pontos fortes e fracos a este respeito

    Técnica de inseminación artificial en gallinas reproductoras: selección de machos, uso de diluyentes, parámetros de inseminación y viabilidad económica

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    La inseminación artificial es una técnica ampliamente empleada en muchas producciones animales. En el caso de las aves, su uso es habitual en los pavos, pero está poco estudiada y empleada en gallinas. En esta Tesis se evalúan los diversos aspectos de esta técnica que presentan influencia en los resultados productivos, valorando su aplicación en la producción industrial: el sistema CASA como técnica de selección de los mejores machos según la motilidad progresiva de los espermatozoides, las diferencias existentes en la fertilidad obtenida en la inseminación artificial con semen puro y diluido, la eficacia de la inseminación en gallinas reproductoras a diferentes frecuencias con semen fresco y la relación entre la fertilidad y el tiempo que transcurre entre la extracción del semen y la inseminación de las hembras

    RanBP2-Mediated SUMOylation Promotes Human DNA Polymerase Lambda Nuclear Localization and DNA Repair

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    Cellular DNA is under constant attack by a wide variety of agents, both endogenous and exogenous. To counteract DNA damage, human cells have a large collection of DNA repair factors. Among them, DNA polymerase lambda (Polλ) stands out for its versatility, as it participates in different DNA repair and damage tolerance pathways in which gap-filling DNA synthesis is required. In this work we show that human Polλ is conjugated with Small Ubiquitin-like MOdifier (SUMO) proteins both in vitro and in vivo, with Lys27 being the main target of this covalent modification. Polλ SUMOylation takes place in the nuclear pore complex and is mediated by the E3 ligase RanBP2. This post-translational modification promotes Polλ entry into the nucleus, which is required for its recruitment to DNA lesions and stimulated by DNA damage induction. Our work represents an advance in the knowledge of molecular pathways that regulate cellular localization of human Polλ, which are essential to be able to perform its functions during repair of nuclear DNA, and that might constitute an important point for the modulation of its activity in human cells

    Full-Wave Computation of Monostatic RCS Using Ray-Tracing and Adaptive Macro-Basis Functions

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    This article presents a technique for the computation of the monostatic radar cross section of complex objects based on a combination of macro-basis functions (MBFs) and the multilevel fast multipole algorithm. An initial pool of excitation-independent MBFs is first obtained, generating the corresponding reduced coupling matrix as well as the multipole data. For each excitation, ray-tracing processing is performed, extracting a number of critical points that are used to obtain a mask that allows to dynamically select the basis functions to be considered in the analysis. This strategy allows a noticeable reduction in the size of the problems with minimal CPU-time preprocessing overhead.Ministry of Economy and Competitiveness and European Unio

    Efficient Technique for the Analysis of Electromagnetic Problems Involving Antenna Trajectories in Complex Scenarios

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    This letter presents an efficient approach for the electromagnetic analysis of complex scenarios involving transmitting antennas moving along predetermined trajectories. In order to efficiently reduce the size of the problem for each position of the antenna, we propose a technique based on macro basis functions that are dynamically generated using a ray-tracing analysis. The multilevel fast multipole algorithm is also included in order to reduce the memory consumption and speed up the solution process. Some representative test cases serve to validate the efficiency and performance of the proposed approach.Ministry of Economy and Competitiveness, Junta de Comunidades de Castilla La Manch, University of Alcal

    Efficient computation of the reduced matrix of MLFMA-CBFM for electrically large blocks

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    In recent years, the characteristic basis function method has been developed as an efficient approach for the solution of large electromagnetic radiation or scattering problems. According to this technique, the currents over the scenario under analysis are defined using a set of pre-computed characteristic basis functions, associated with a number of blocks into which the geometry is partitioned. This involves some computational advantages due to the reduction of the number of unknowns compared to conventional approaches. However, additional pre-processing time is introduced due to the computation of the CBFs and the reduced coupling matrix. A novel strategy is presented in this study in order to accelerate the generation of the reduced matrix, based on the application of the multilevel fast multipole algorithm.Spanish Ministry of Economy and Competitiveness Project, Junta de Comunidades de Castilla La Mancha and Universidad de Alcal

    Analysis of the correlation between deformation and temperature in a concrete dam

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    Deformational control of structures has its greatest exponent in large dams monitoring, which, depending on their structural typology, can be subjected to movements generally based on both the pressure that they upport and the temperature.The designer usually calculates the theoretical displacements that the dam will suffer onsidering the hydrostatic thrust and the temperature, but it is also true that these displacements are theoretical and they do not often fit to the real movements, due to the uncertainties that arise during the onstruction of any dam and make the final structure have changes which can be more or less significant with respect to the originally projected one. However, it is worth mentioning that they are usually lower than those theoretically calculated. The present research work focuses on a potential correlation and the subsequent determination of an mpirical model that allows calculating the deformation by means of a polynomial fit, working on the basis of temperature observations held over 14 years. This empirical model is contrasted and validated with the observations taken during the following year, and although it is only valid for the dam where the test has been made (“La Cohilla” Dam), the methodology is suitable for any other structure

    Determination of an empirical model for calculating the strain of a dam in terms of hydrostatic thrust

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    The deformational control of structures has its greatest exponent in the control of large dams, which depending on structural typology, can be subjected to movement generally based on the pressure that it suffers. The designer usually calculates the theoretical displacements that the dam must suffer depending on the ydrostatic pressure, function of the thrust bearing, but it is also true that this calculation is theoretical and it is not usually adjusted to the real movements, due to the uncertainties that arise in the construction of any dam and make the original project have more or less significant changes in the final construction. In favour of the builder, it must be said that the actual displacements are usually lower than the theoretical ones. The present research focuses on the determination of an empirical model that allows calculating the deformation based on practical observations of a direct pendulum over 14 years, which determines the isplacement and the pressure experienced by the dam represented by the height of water contained, by means of a polynomial adjustment. This empirical model is tested and then validated with observations over the ollowing year and, although it is only valid for the dam where the trial (La Cohilla Dam) is made, the ethodology is applicable to any other structure
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