Maternal Thyroid Dysfunction and Neonatal Thyroid Problems

Aim. To investigate obstetric features of pregnant women with thyroid disorders and thyroid function tests of their newborn infants. Methods. Women with hypothyroidism and having anti-thyroglobulin (ATG) and anti-thyroid peroxidase (anti-TPO) antibodies were assigned as group I, women with hypothyroidism who did not have autoantibodies were assigned as group II, and women without thyroid problems were assigned as group III. Results. Pregnant women with autoimmune hypothyroidism (group I) had more preterm delivery and their babies needed more frequent neonatal intensive care unit (NICU) admission. In group I, one infant was diagnosed with compensated hypothyroidism and one infant had transient hyperthyrotropinemia. Five infants (23.8%) in group II had thyroid-stimulating hormone (TSH) levels >20 mIU/mL. Only two of them had TSH level >7 mIU/L at the 3rd postnatal week, and all had normal free T4 (FT4). Median maternal TSH level of these five infants with TSH >20 mIU/mL was 6.6 mIU/mL. In group III, six infants (6.5%) had TSH levels above >20 mIU/mL at the 1st postnatal week. Conclusion. Infants of mothers with thyroid problems are more likely to have elevated TSH and higher recall rate on neonatal thyroid screening. Women with thyroid disorders and their newborn infants should be followed closely for both obstetrical problems and for thyroid dysfunction

Proceedings: 1st International Conference on Food and Agricultural Economics: SUSTAINABLE DEVELOPMENT AND SUSTAINABLE AGRICULTURE IMPLEMENTATIONS IN AN AGRI-FOOD COMPANY: CASE OF KAYSERI SUGAR FACTORY

Sustainable development means programming the life of today and tomorrow so that it can balance the natural environment with human beings and allow the needs of future generations to be met without finishing the entire natural resources. Sustainable development suggests that natural resources should be used to remain in future generations. For this reason, sustainable development has become an important issue globally. The 2030 Sustainable Development Goals accepted by 193 countries at the UN Sustainable Development Summit held in 2015 is one of the best examples of importance of sustainable development. In this study, sustainable development in agriculture, which is one of the most important topics of sustainable development, is discussed. The social, economic, environmental, sectoral, geographical and temporal dimensions that are among the generally accepted dimensions of sustainable development are defined. Later, the UN 2030 sustainable development targets were introduced and the current situation in the world and in Turkey in sustainable development was examined. Then, sustainability in agriculture was addressed and the ecological, social and economic dimensions of sustainable agriculture were discussed. Within the scope of this study, in Kayseri Şeker Fabrikası A.Ş., one of the most important producers of agricultural production in Turkey and Kayseri, sustainable agriculture studies carried out were examined. Kayseri Şeker Fabrikası A.Ş. According to sales from production, it is among the top 500 industrial enterprises and it is the 101st largest enterprise in Turkey according to the data of 2015. A case study has been carried out in the study and social, environmental, economic and temporal dimensions within the context of the sustainable agricultural activities carried out in the last 5 years by the company have been reviewed and interpreted. Among the findings of the study, the social aspects of sustainable agricultural activities carried out in the business seem to have come to the fore such as open door, happy employee- happy business, farmer awareness and farmer promotion. In the economic dimension of sustainability, economic benefits such as water savings, savings in transportation costs, energy savings and new products obtaining from wastes have come to the forefront. On the other side, in the environmental dimension the issues of soil-rehabilitation, waste management, environmentally sensitive struggle against soil and beet pests come forward. Finally, in terms of temporal dimension the land and product tracking system comes to the forefront through the geographic information system

The Role of Perceived Social Support on Physical Activity Participation of 6th to 8th Grade Students

The purpose of this study was to investigate the role of perceived social support on 6th, 7th and 8th grade students' physical activity levels with regard to gender and school type (private versus public). In this study, both qualitative and quantitative research methodologies were applied. The participants were 266 students from one public and one private school. It is found that perceived social support seems to be an important factor on students' physical activity patterns. Participants reported that they received more social support from their peers when compared to their parents, wherein their mothers were the only significant social support provider. Results also revealed that students from the private school significantly received more social support from their family compared to students from the public school. Moreover, physically active students, especially girls, reported that they received more social support from their mothers

Platelet-rich plasma and platelet-derived lipid factors induce different and similar gene expression responses for selected genes related to wound healing in rat dermal wound environment

Although platelet-rich plasma (PRP) is the plasma fraction that contains higher levels of platelet-sequestered proteins such as growth factors and chemokines, it is also abundant in bioactive lipids whose role in wound healing has not been well characterized. This study provides a preliminary evaluation for the effect of the lipid component of PRP on selected genes related to wound healing. Sprague-Dawley rats were classified into four groups after induction of full thickness excisional wounds: the lipid fraction (LF) (lipid extract from PRP) group, PRP group, dimethyl sulfoxide group, and sham group. Subsequently, relevant groups were topically treated with test preparations. Healing wounds were collected on 3rd, 7th and 14th days, and expression levels of 12 genes were determined using qPCR. LF treatment-induced gene expression signature distinct from that induced by PRP treatment, although there are some overlaps in LF- and PRP-responsive genes. Differentially expressed all eight genes (Cxcl5, Cxc11, Egfr, Tgfb1, IL10, Tgfa, Mmp1, and Mmp7) to LF response were significantly down-regulated at either 3rd, 7th, or 14th days. Also, the comparison between LF- and PRP-treatment groups showed that the LF significantly decreased expression of Cxcl11, Mmp7, and Tgfa mRNA on day 7 of healing. This study revealed that PRP and its LF induced different and similar gene expression responses of the skin during the repair of full thickness excisional wounds. Identifying mRNA response to LF treatment at whole transcriptome level can be beneficial for comprehensive understanding of the role of platelet-derived lipid factors in wound healing processes

Effect of Chronic Periodontitis on Serum and Gingival Crevicular Fluid Oxidant and Antioxidant Status in Patients With Familial Mediterranean Fever Before and After Periodontal Treatment

Background: The aim of this study is to investigate the impact of periodontal status on oxidant/antioxidant status in patients with chronic periodontitis (CP) who experienced familial Mediterranean fever (FMF) and their response to non-surgical periodontal therapy.Background: The aim of this study is to investigate the impact of periodontal status on oxidant/antioxidant status in patients with chronic periodontitis (CP) who experienced familial Mediterranean fever (FMF) and their response to non-surgical periodontal therapy.Methods: Data were obtained from 13 patients with FMF with generalized CP (FMF-CP), 15 systemically healthy patients with generalized CP, 15 systemically and periodontal healthy controls (HCs), and 14 periodontally healthy patients with FMF (FMF-HC). Each participant&rsquo;s total oxidant status (TOS), total antioxidant status (TAS), and oxidative stress index (OSI) in their gingival crevicular fluid (GCF) and serum were recorded. Probing depth, clinical attachment level, and gingival and plaque indices in each participant were also measured. The GCF and clinical parameters at baseline and 6 weeks after periodontal treatment were recorded.Results: The study showed statistically significant improvement of clinical parameters in both FMF-CP and CP groups after periodontal treatment. The baseline GCF-TOS and OSI levels were significantly higher in the CP group compared with the FMF-CP group (P &lt;0.05). After periodontal treatment, the GCF-TOS levels were significantly reduced in members of the FMF-CP group (P &lt;0.05). The GCF-TAS levels in members of the FMF-CP group were significantly higher than those of members of the HC group at baseline (P &lt;0.05). Serum-TAS levels in the FMF-CP group were significantly higher than those in the CP and HC groups at baseline (P &lt;0.05). The GCF-TOS level in the FMF-CP group was significantly higher than that in the FMF-HC group at baseline and 6 weeks. However, there were no significant differences in the serum-TOS and serum-OSI levels of those in the FMF-CP and CP groups at baseline and 6 weeks (P &gt;0.05).Conclusion: The results of the present study show that patients with FMF-CP displayed reduced oxidative stress and increased antioxidant status compared with those in the CP and HC groups.</p