The Effects of Night-time Temperatures on Physiological and Biochemical Traits in Rice

High nighttime temperatures impair rice yield. Additionally, heat stress periods have increased during the last years in the rice areas of the tropics. The aim of this study was to physiologically characterize six genotypes of rice (a commercial cultivar (ʻF60ʼ) and five selected lines (ʻIR 1561ʼ, ʻFLO 2764ʼ, ʻLV447-1ʼ, ʻCT19021ʼ, and ʻLV1401ʼ) subjected to two nighttime temperatures (24 and 30 °C), based on different physiological traits. When the collar formed on leaf 6 of the main stem, one group of six plants in each genotype was subjected to 30 °C from 18:00 to 24:00 hours for eight days, while the other group remained at 24 °C. Differences were found in the interaction between genotype and nighttime temperatures, where a high night temperature reduced leaf photosynthesis by approximately 50% in all genotypes compared to the controls (20 µmol vs. 10 µmol CO2 m-2 s-1, respectively). In general, higher plant respiration was also observed in almost all genotypes when the plants were exposed to 30 °C. However, rice plants of the genotype ʻF60ʼ showed a constant respiration under two different night temperatures. A high nighttime temperature increased the electrolyte leakage and malondialdehyde content only in the ʻLV1401ʼ plants. Plant growth and Fv/Fm ratio were separately conditioned by the night temperature or the genotype factor. A lower total plant dry weight was found at 30 °C (620.36 mg) than in rice plants exposed to 24 °C (254.16 mg). The Fv/Fm ratio was slightly diminished at a high nighttime temperature. These results suggest that physiological variables, such as leaf photosynthesis, plant respiration, malondialdehyde content and leaf photosynthetic pigments, can be considered markers for characterizing tolerant genotypes in earlier growth phases during plant breeding programs

Developing a Framework for the Study of Performing Arts Programs for Other-than-artistic Purposes in Conflict Settings

This paper discusses the process of developing a new framework combining ideas from Community Music (Howell, 2018), Social Psychology (Pettigrew, 1998; Odena, 2018) and Peace Studies (Cabedo-Mas, 2015), aimed at providing a tool for researchers wishing to systematically examine Performing Arts programs for other-than-artistic purposes in conflict settings. The framework could also be a tool for organizers and practitioners wishing to reflect on their work and to position it within the wider conflict recovery context. The process of framework development is ongoing, and is part of the activities of a new network including members from Colombia, Mexico, Brazil, Spain and the UK, supported by the AHRC and the Royal Society of Edinburgh (2019-2021) and informed by an international Advisory group. The second part of the paper shares the network’s planned activities and selected aspects of a recent doctorate by one of its members (Rodríguez-Sánchez, 2019). Once the framework is developed, we will consider its illuminating potential within the intercultural, political and socioeconomic complexity of conflict settings

Simulating the detection of the global 21 cm signal with MIST for different models of the soil and beam directivity

The Mapper of the IGM Spin Temperature (MIST) is a new ground-based, single-antenna, radio experiment attempting to detect the global 21 cm signal from the Dark Ages and Cosmic Dawn. A significant challenge in this measurement is the frequency-dependence, or chromaticity, of the antenna beam directivity. MIST observes with the antenna above the soil and without a metal ground plane, and the beam directivity is sensitive to the electrical characteristics of the soil. In this paper, we use simulated observations with MIST to study how the detection of the global 21 cm signal from Cosmic Dawn is affected by the soil and the MIST beam directivity. We simulate observations using electromagnetic models of the directivity computed for single- and two-layer models of the soil. We test the recovery of the Cosmic Dawn signal with and without beam chromaticity correction applied to the simulated data. We find that our single-layer soil models enable a straightforward recovery of the signal even without chromaticity correction. Two-layer models increase the beam chromaticity and make the recovery more challenging. However, for the model in which the bottom soil layer has a lower electrical conductivity than the top layer, the signal can be recovered even without chromaticity correction. For the other two-layer models, chromaticity correction is necessary for the recovery of the signal and the accuracy requirements for the soil parameters vary between models. These results will be used as a guideline to select observation sites that are favorable for the detection of the Cosmic Dawn signal.Comment: Accepted for publication in the Astrophysical Journa

Metabolic Signatures Associated with Severity in Hospitalized COVID-19 Patients

The clinical evolution of COVID-19 pneumonia is poorly understood. Identifying the metabolic pathways that are altered early with viral infection and their association with disease severity is crucial to understand COVID-19 pathophysiology, and guide clinical decisions. This study aimed at assessing the critical metabolic pathways altered with disease severity in hospitalized COVID-19 patients. Forty-nine hospitalized patients with COVID-19 pneumonia were enrolled in a prospective, observational, single-center study in Barcelona, Spain. Demographic, clinical, and analytical data at admission were registered. Plasma samples were collected within the first 48 h following hospitalization. Patients were stratified based on the severity of their evolution as moderate (N = 13), severe (N = 10), or critical (N = 26). A panel of 221 biomarkers was measured by targeted metabolomics in order to evaluate metabolic changes associated with subsequent disease severity. Our results show that obesity, respiratory rate, blood pressure, and oxygen saturation, as well as some analytical parameters and radiological findings, were all associated with disease severity. Additionally, ceramide metabolism, tryptophan degradation, and reductions in several metabolic reactions involving nicotinamide adenine nucleotide (NAD) at inclusion were significantly associated with respiratory severity and correlated with inflammation. In summary, assessment of the metabolomic profile of COVID-19 patients could assist in disease severity stratification and even in guiding clinical decisions

Can Music be a Tool for Social Transformation?

This Open Access brochure for secondary schools profiles the work of eight network members and includes an activity sheet

The inert Zee model

ABSTRACT: We study a realization of the topology of the Zee model for the generation of neutrino masses at one-loop with a minimal set of vector-like fermions. After imposing an exact Z2 symmetry to avoid tree-level Higgs-mediated avor changing neutral currents, one dark matter candidate is obtained from the subjacent inert doublet model, but with the presence of new co-annihilating particles. We show that the model is consistent with the constraints coming from lepton avor violation processes, oblique parameters, dark matter and neutrino oscillation data

Evaluation of dengue fever reports during an epidemic, Colombia

OBJECTIVE To assess the validity of dengue fever reports and how they relate to the definition of case and severity. METHODS Diagnostic test assessment was conducted using cross-sectional sampling from a universe of 13,873 patients treated during the fifth epidemiological period in health institutions from 11 Colombian departments in 2013. The test under analyses was the reporting to the National Public Health Surveillance System, and the reference standard was the review of histories identified by active institutional search. We reviewed all histories of patients diagnosed with dengue fever, as well as a random sample of patients with febrile syndromes. The specificity and sensitivity of reports were estimated for this purpose, considering the inverse of the probability of being selected for weighting. The concordance between reporting and the findings of the active institutional search was calculated using Kappa statistics. RESULTS We included 4,359 febrile patients, and 31.7% were classified as compatible with dengue fever (17 with severe dengue fever; 461 with dengue fever and warning signs; 904 with dengue fever and no warning signs). The global sensitivity of reports was 13.2% (95%CI 10.9;15.4) and specificity was 98.4% (95%CI 97.9;98.9). Sensitivity varied according to severity: 12.1% (95%CI 9.3;14.8) for patients presenting dengue fever with no warning signs; 14.5% (95%CI 10.6;18.4) for those presenting dengue fever with warning signs, and 40.0% (95%CI 9.6;70.4) for those with severe dengue fever. Concordance between reporting and the findings of the active institutional search resulted in a Kappa of 10.1%. CONCLUSIONS Low concordance was observed between reporting and the review of clinical histories, which was associated with the low reporting of dengue fever compatible cases, especially milder cases

P. brasiliensis virulence is affected by SconC, the negative regulator of inorganic sulfur assimilation

Conidia/mycelium-to-yeast transition of Paracoccidioidesbrasiliensis is a critical step for the establishment of paracoccidioidomycosis, a systemic mycosis endemic in Latin America. Thus, knowledge of the factors that mediate this transition is of major importance for the design of intervention strategies. So far, the only known pre-requisites for the accomplishment of the morphological transition are the temperature shift to 37°C and the availability of organic sulfur compounds. In this study, we investigated the auxotrophic nature to organic sulfur of the yeast phase of Paracoccidioides, with special attention to P. brasiliensis species. For this, we addressed the role of SconCp, the negative regulator of the inorganic sulfur assimilation pathway, in the dimorphism and virulence of this pathogen. We show that down-regulation of SCONC allows initial steps of mycelium-to-yeast transition in the absence of organic sulfur compounds, contrarily to the wild-type fungus that cannot undergo mycelium-to-yeast transition under such conditions. However, SCONC down-regulated transformants were unable to sustain yeast growth using inorganic sulfur compounds only. Moreover, pulses with inorganic sulfur in SCONC down-regulated transformants triggered an increase of the inorganic sulfur metabolism, which culminated in a drastic reduction of the ATP and NADPH cellular levels and in higher oxidative stress. Importantly, the down-regulation of SCONC resulted in a decreased virulence of P. brasiliensis, as validated in an in vivo model of infection. Overall, our findings shed light on the inability of P. brasiliensis yeast to rely on inorganic sulfur compounds, correlating its metabolism with cellular energy and redox imbalances. Furthermore, the data herein presented reveal SconCp as a novel virulence determinant of P. brasiliensis.J.F.M. and J.G.R. were supported by a PhD grant from Fundacao para a Ciencia e Tecnologia (FCT). This work was supported by a grant from FCT (PTDC/BIA-MIC/108309/2008). M. Sturme. and M. Saraiva are Ciencia 2008 fellows. The authors would also like to thank FAPESP (Fundacao para Amparo a Pesquisa do Estado de Sao Paulo) and CNPq (Conselho Nacional de Desenvolvimento Cientifico e Tecnologico) for financial support. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

Criterios biológicos y ecológicos: aportes para la identificación, caracterización y delimitación de los humedales interiores de Colombia.

Este producto es elaborado por el Programa Biología de la Conservación y Uso de la Biodiversidad en el marco del convenio 005 (13-014) entre el Instituto Humboldt y el Fondo Adaptación, en este documento se asume los principios generales de los ecosistemas, en los que se caracterizan como sistemas complejos, abiertos, dinámicos e integrados en donde los patrones ecológicas y la diversidad biológica son el resultado de un proceso biogeográfico que a su vez es afectado por procesos antrópicos. Es por ello que los ecosistemas de humedales de interior son considerados unidades funcionales en los que son necesarias las conexiones de la transición de hábitats en función de la pendiente natural (cuenca aguas arriba y abajo), hacia los ecosistemas adyacentes terrestres y dentro del cuerpo de agua (entre las zonas someras y profundas).Bogotá, ColombiaPrograma Biología de la Conservación y Uso de la Biodiversida