Evidences of a possible Islamic Watermill in La Majada (Mazarrón, Region of Murcia)

En las inmediaciones de La Majada, Mazarrón, y como parte de un sistema hidráulico más complejo, se encuentran los restos de un antiguo molino de agua cuyo cubo presenta un singular revestimiento interno formado por una sucesión de anillos cerámicos superpuestos o atanores. El análisis integral de la construcción tendrá como base principal la comparación de este ingenio molinar con otros paralelos en los que se usó dicho recurso arquitectónico, además de relacionar el conjunto y su entorno con una serie de elementos de la hidráulica andalusí cuya presencia histórica en la zona se atisba como algo más que una mera conjetura; convirtiéndose, todo ello, en hitos clave para la datación del inmueble.In the vicinity of La Majada, Mazarrón, and as part of a more complex hydraulic system, there are the remains of a watermill whose cube has a unique internal coating formed by a succession of ceramic rings overlapping. The basis of this construction comprehensive analysis will be the comparison of this mill with other similar ones in which this architectural resource was also used. In addition, the industrial building and his surroundings are related with a lot of differents islamic hydraulic elements whose historical presence in this area suggests more than just a wild guess. All in all, this facts analysed are a key milestone for dating the building

Evidencias de un posible molino hidráulico andalusí en el campo de Mazarrón, Murcia

In the vicinity of La Majada, Mazarrón, and as part of a more complex hydraulic system, there are the remains of a watermill whose cube has a unique internal coating formed by a succession of ceramic rings overlapping. The basis of this construction comprehensive analysis will be the comparison of this mill with other similar ones in which this architectural resource was also used. In addition, the industrial building and his surroundings are related with a lot of differents islamic hydraulic elements whose historical presence in this area suggests more than just a wild guess. All in all, this facts analysed are a key milestone for dating the building.En las inmediaciones de La Majada, Mazarrón, y como parte de un sistema hidráulico más complejo, se encuentran los restos de un antiguo molino de agua cuyo cubo presenta un singular revestimiento interno formado por una sucesión de anillos cerámicos superpuestos o atanores. El análisis integral de la construcción tendrá como base principal la comparación de este ingenio molinar con otros paralelos en los que se usó dicho recurso arquitectónico, además de relacionar el conjunto y su entorno con una serie de elementos de la hidráulica andalusí cuya presencia histórica en la zona se atisba como algo más que una mera conjetura; convirtiéndose, todo ello, en hitos clave para la datación del inmueble

Contemporary use of cefazolin for MSSA infective endocarditis: analysis of a national prospective cohort

Objectives: This study aimed to assess the real use of cefazolin for methicillin-susceptible Staphylococcus aureus (MSSA) infective endocarditis (IE) in the Spanish National Endocarditis Database (GAMES) and to compare it with antistaphylococcal penicillin (ASP). Methods: Prospective cohort study with retrospective analysis of a cohort of MSSA IE treated with cloxacillin and/or cefazolin. Outcomes assessed were relapse; intra-hospital, overall, and endocarditis-related mortality; and adverse events. Risk of renal toxicity with each treatment was evaluated separately. Results: We included 631 IE episodes caused by MSSA treated with cloxacillin and/or cefazolin. Antibiotic treatment was cloxacillin, cefazolin, or both in 537 (85%), 57 (9%), and 37 (6%) episodes, respectively. Patients treated with cefazolin had significantly higher rates of comorbidities (median Charlson Index 7, P <0.01) and previous renal failure (57.9%, P <0.01). Patients treated with cloxacillin presented higher rates of septic shock (25%, P = 0.033) and new-onset or worsening renal failure (47.3%, P = 0.024) with significantly higher rates of in-hospital mortality (38.5%, P = 0.017). One-year IE-related mortality and rate of relapses were similar between treatment groups. None of the treatments were identified as risk or protective factors. Conclusion: Our results suggest that cefazolin is a valuable option for the treatment of MSSA IE, without differences in 1-year mortality or relapses compared with cloxacillin, and might be considered equally effective