The Influence of Specimen Thickness on the High Temperature Corrosion Behavior of CMSX-4 during Thermal-Cycling Exposure

CMSX-4 is a single-crystalline Ni-base superalloy designed to be used at very high temperatures and high mechanical loadings. Its excellent corrosion resistance is due to external alumina-scale formation, which however can become less protective under thermal-cycling conditions. The metallic substrate in combination with its superficial oxide scale has to be considered as a composite suffering high stresses. Factors like different coefficients of thermal expansion between oxide and substrate during temperature changes or growing stresses affect the integrity of the oxide scale. This must also be strongly influenced by the thickness of the oxide scale and the substrate as well as the ability to relief such stresses, e.g., by creep deformation. In order to quantify these effects, thin-walled specimens of different thickness (t = 100500 lm) were prepared. Discontinuous measurements of their mass changes were carried out under thermal-cycling conditions at a hot dwell temperature of 1100 C up to 300 thermal cycles. Thin-walled specimens revealed a much lower oxide-spallation rate compared to thick-walled specimens, while thinwalled specimens might show a premature depletion of scale-forming elements. In order to determine which of these competetive factor is more detrimental in terms of a component’s lifetime, the degradation by internal precipitation was studied using scanning electron microscopy (SEM) in combination with energy-dispersive X-ray spectroscopy (EDS). Additionally, a recently developed statistical spallation model was applied to experimental data [D. Poquillon and D. Monceau, Oxidation of Metals, 59, 409–431 (2003)]. The model describes the overall mass change by oxide scale spallation during thermal cycling exposure and is a useful simulation tool for oxide scale spallation processes accounting for variations in the specimen geometry. The evolution of the net-mass change vs. the number of thermal cycles seems to be strongly dependent on the sample thickness

Orbital Parameters for the Black Hole Binary XTE J1650-500

(Shortened) We present R-band photometry of the X-ray transient and candidate black hole binary XTE J1650-500 obtained between 2003 May and August with the 6.5m Clay Telescope. A timing analysis of these data reveals a photometric period of 0.3205 +/- 0.0007 days (i.e. 7.63 hr) with a possible alias at 0.3785 days (9.12 hr). Our photometry completely rules out the previously published spectroscopic period of 0.212 days (5.09 hr). Consequently, we reanalyzed the 15 archival ESO/VLT spectra (obtained 2002 June by Sanchez-Fernandez et al.) that were the basis of the previously published spectroscopic period. We used a ``restframe search'' technique that is well suited for cases when the signal-to-noise ratio of individual spectra is low. The results confirmed the photometric period of 0.3205 days, and rule out the alias period near 0.38 days. The best value for the velocity semiamplitude of the companion star is K_2 = 435 +/- 30 km/sec, and the corresponding optical mass function is f(M) = 2.73 +/- 0.56 solar masses. The amplitude of the phased R-band light curve is 0.2 magnitudes, which gives a lower limit to the inclination of 50 +/- 3 degrees in the limiting case of no contribution to the R-band light curve from the accretion disk. If the mass ratio of XTE J1650-500 is similar to the mass ratios of other black hole binaries like A0620-00 or GRS 1124-683 (e.g. Q >~ 10), then our lower limit to the inclination gives an upper limit to the mass of the black hole in XTE J1650-500 of M_1 <~ 7.3 solar masses. However, the mass can be considerably lower if the R-band flux is dominated by the accretion disk. For example, if the accretion disk does contribute 80% of the flux, as our preliminary results suggest, then the black hole mass would be only about 4 solar masses.Comment: Accepted to ApJ. 15 pages, 5 figures (two of degraded quality). Revised after referee's Comments, conclusions are unchange

NGC 300 X-1 is a Wolf-Rayet/Black-Hole binary

We present VLT/FORS2 time-series spectroscopy of the Wolf-Rayet star #41 in the Sculptor group galaxy NGC 300. We confirm a physical association with NGC 300 X-1, since radial velocity variations of the HeII 4686 line indicate an orbital period of 32.3 +/- 0.2 hr which agrees at the 2 sigma level with the X-ray period from Carpano et al. We measure a radial velocity semi-amplitude of 267 +/- 8 km/s, from which a mass function of 2.6 +/- 0.3 Msun is obtained. A revised spectroscopic mass for the WN-type companion of 26+7-5 Msun yields a black hole mass of 20 +/- 4 Msun for a preferred inclination of 60-75 deg. If the WR star provides half of the measured visual continuum flux, a reduced WR (black hole) mass of 15 +4 -2.5 Msun (14.5 +3 -2.5 Msun) would be inferred. As such, #41/NGC 300 X-1 represents only the second extragalactic Wolf-Rayet plus black-hole binary system, after IC 10 X-1. In addition, the compact object responsible for NGC 300 X-1 is the second highest stellar-mass black hole known to date, exceeded only by IC 10 X-1.Comment: 5 pages, 6 figures, MNRAS Letters in press. Images and animations available from http://www.eso.org/public/news/eso1004/ at 11am GMT on 27 Jan 1

Geometric Design of Scroll Expanders Optimized for Small Organic Rankine Cycles

The application of organic Rankine cycles (ORCs) for small scale power generation is inhibited by a lack of suitable expansion devices. Thermodynamic and mechanistic considerations suggest that scroll machines are advantageous in kilowatt-scale ORC equipment, however, a method of independently selecting a geometric design optimized for high-volume-ratio ORC scroll expanders is needed. The generalized 8-dimensional planar curve framework (Gravesen and Henriksen, 2001, “The Geometry of the Scroll Compressor,” Soc. Ind. Appl. Math., 43, pp. 113–126), previously developed for scroll compressors, is applied to the expansion scroll and its useful domain limits are defined. The set of workable scroll geometries is: (1) established using a generate-and-test algorithm with inclusion based on theoretical viability and engineering criteria, and (2) the corresponding parameter space is related to thermodynamically relevant metrics through an analytic ranking quantity fc (“compactness factor”) equal to the volume ratio divided by the normalized scroll diameter. This method for selecting optimal scroll geometry is described and demonstrated using a 3 kWe ORC specification as an example. Workable scroll geometry identification is achieved at a rate greater than 3 s⁻¹ with standard desktop computing, whereas the originally undefined 8-D parameter space yields an arbitrarily low success rate for determining valid scroll mating pairs. For the test case, a maximum isentropic expansion efficiency of 85% is found by examining a subset of candidates selected the for compactness factor (volume expansion ratio per diameter), which is shown to correlate with the modeled isentropic efficiency (R² = 0.88). The rapid computationally efficient generation and selection of complex validated scroll geometries ranked by physically meaningful properties is demonstrated. This procedure represents an essential preliminary qualification for intensive modeling and prototyping efforts necessary to generate new high performance scroll expander designs for kilowatt scale ORC systems.United States. Environmental Protection Agency (SU 83436701

Dynamical Masses for the Large Magellanic Cloud Massive Binary System [L72] LH 54-425

We present results from an optical spectroscopic investigation of the massive binary system [L72] LH~54-425 in the LH 54 OB association in the Large Magellanic Cloud. We revise the ephemeris of [L72] LH 54-425 and find an orbital period of 2.247409 +/- 0.000010 days. We find spectral types of O3 V for the primary and O5 V for the secondary. We made a combined solution of the radial velocities and previously published V-band photometry to determine the inclination for two system configurations, i = 52 degrees for the configuration of the secondary star being more tidally distorted and i = 55 degrees for the primary as the more tidally distorted star. We argue that the latter case is more probable, and this solution yields masses and radii of M_1 = 47 +/- 2 M_Sun and R_1 = 11.4 +/- 0.1 R_Sun for the primary, and M_2 = 28 +/- 1 M_Sun and R_2 = 8.1 +/- 0.1 R_Sun for the secondary. Our analysis places LH 54-425 amongst the most massive stars known. Based on the position of the two stars plotted on a theoretical HR diagram, we find the age of the system to be about 1.5 Myr.Comment: 21 pages, 6 figures. Accepted in ApJ. To appear vol. 683, Aug. 10t

An Extended and More Sensitive Search for Periodicities in RXTE/ASM X-ray Light Curves

We present the results of a systematic search in approximately 14 years of Rossi X-ray Timing Explorer All-Sky Monitor data for evidence of periodicities not reported by Wen et al. (2006). Two variations of the commonly used Fourier analysis search method have been employed to achieve significant improvements in sensitivity. The use of these methods and the accumulation of additional data have resulted in the detection of the signatures of the orbital periods of eight low-mass X-ray binary systems and of ten high-mass X-ray binaries not listed in the tables of Wen et al.Comment: 20 pages, 22 figures, in emulateapj format; submitted to ApJ

Chandra Detections of Two Quiescent Black Hole X-Ray Transients

Using the Chandra X-ray Observatory, we have detected the black hole transients V4641 Sgr and XTE J1859+226 in their low luminosity, quiescent states. The 0.3-8 keV luminosities are (4.0^(+3.3)_(-2.4))E31 (d/7 kpc)^2 erg/s and (4.2^(+4.8)_(-2.2))E31 (d/11 kpc)^2 erg/s for V4641 Sgr and XTE J1859+226, respectively. With the addition of these 2 systems, 14 out of the 15 transients with confirmed black holes (via compact object mass measurements) now have measured quiescent luminosities or sensitive upper limits. The only exception is GRS 1915+105, which has not been in quiescence since its discovery in 1992. The luminosities for V4641 Sgr and XTE J1859+226 are consistent with the median luminosity of 2E31 erg/s for the systems with previous detections. Our analysis suggests that the quiescent X-ray spectrum of V4641 Sgr is harder than for the other systems in this group, but, due to the low statistical quality of the spectrum, it is not clear if V4641 Sgr is intrinsically hard or if the column density is higher than the interstellar value. Focusing on V4641 Sgr, we compare our results to theoretical models for X-ray emission from black holes in quiescence. Also, we obtain precise X-ray positions for V4641 Sgr and XTE J1859+226 via cross-correlation of the X-ray sources detected near our targets with IR sources in the 2 Micron All-Sky Survey catalog.Comment: 4 pages, Accepted by ApJ Letter

Optical Photometry and Spectroscopy of the Accretion-Powered Millisecond Pulsar HETE J1900.1-2455

We present phase resolved optical photometry and spectroscopy of the accreting millisecond pulsar HETE J1900.1-2455. Our R-band light curves exhibit a sinusoidal modulation, at close to the orbital period, which we initially attributed to X-ray heating of the irradiated face of the secondary star. However, further analysis reveals that the source of the modulation is more likely due to superhumps caused by a precessing accretion disc. Doppler tomography of a broad Halpha emission line reveals an emission ring, consistent with that expected from an accretion disc. Using the velocity of the emission ring as an estimate for the projected outer disc velocity, we constrain the maximum projected velocity of the secondary to be 200 km/s, placing a lower limit of 0.05 Msun on the secondary mass. For a 1.4 Msun primary, this implies that the orbital inclination is low, < 20 degrees. Utilizing the observed relationship between the secondary mass and orbital period in short period cataclysmic variables, we estimate the secondary mass to be ~0.085 Msun, which implies an upper limit of ~2.4 Msun for the primary mass.Comment: 8 pages, 6 figures; Accepted for publication in MNRAS. Minor revisions to match final published versio

Progress in the development of early diagnosis and a drug with unique pharmacology to improve cancer therapy

Cancer continues to be one of the major health and socio-economic problems worldwide, despite considerable efforts to improve its early diagnosis and treatment. The identification of new constituents as biomarkers for early diagnosis of neoplastic cells and the discovery of new type of drugs with their mechanistic actions are crucial to improve cancer therapy. New drugs have entered the market, thanks to industrial and legislative efforts ensuring continuity of pharmaceutical development. New targets have been identified, but cancer therapy and the anti-cancer drug market still partly depend on anti-mitotic agents. The objective of this paper is to show the effects of KAR-2, a potent anti-mitotic compound, and TPPP/p25, a new unstructured protein, on the structural and functional characteristics of the microtubule system. Understanding the actions of these two potential effectors on the microtubule system could be the clue for early diagnosis and improvement of cancer therapy