Poaceae and Fabaceae of meadows of Poltava region and their protein value

The main representatives of meadow Poaceae and Fabaceae of Poltava region are established and their ecomorphic analysis is made 93 species of meadow Poaceae have been found in meadow phytocenoses, which are grouped into 44 genera. Among the found cereals on biomorphs are dominated by perennials (73.0%), on climamorphs among them approximately the same number of cryptophytes and hemicryptophytes, consideration of hygromorphs of the family indicates the predominance of mesophytic plants (56.0%), the bulk of species by tropomorphs belongs to mesotrophic (46.0%), viewing heliomorphs of identified family members indicates their photophobia. 71 species of Fabaceae belonging to 16 genera were found in the meadows. According to biomorphs, most of the identified species are perennials (73.0%). According to ecomorphs, mesophilic, light-loving species, which love soils of medium richness (more than half of all identified species), predominate among the studied species. The consequences of studying the protein in meadow Poaceae and Fabaceae of Poltava region are given. The total protein accumulation in the species studied by us was in the range of 2.5–25.8%. The average values for families are given and specific quantitative indicators of separate genera and species are given. The division of the studied species into three groups according to the content of the indicator is proposed: with low (up to 6.9%), medium (7.0-13.0%) and high (more than 13.0%) number. The studied species were analyzed on a scale of protein content (from 0 to 20 points). According to the given score, the studied cereals are in the group of species with low and medium content, and legumes - medium and high.  In the dynamics of protein content during the phases of the growing season you can see a certain trend. Maximum protein is accumulated by representatives at earlier stages of ontogenesis. Analysis of the indicator, depending on their relationship to the biomorph showed some patterns. Thus, annual species, on average, contain an indicator at the level of the second group, and perennial - all three groups. Two-year-olds most often have protein at the level of the third group. This is understandable because they need a lot of nutrients for overwintering and active flowering and fruit formation  next year. Moisture conditions also affect protein accumulation. Thus, the studied xerophilous Poaceae according to our research have 9.2 ± 0.4%, mesophilic - 8.2 ± 1.2%. Proven value biomorfy to quantify protein content. It is shown that the concentration parameter affecting growing conditions, including moisture

Immunoglobulin, glucocorticoid, or combination therapy for multisystem inflammatory syndrome in children: a propensity-weighted cohort study.

BACKGROUND: Multisystem inflammatory syndrome in children (MIS-C), a hyperinflammatory condition associated with SARS-CoV-2 infection, has emerged as a serious illness in children worldwide. Immunoglobulin or glucocorticoids, or both, are currently recommended treatments. METHODS: The Best Available Treatment Study evaluated immunomodulatory treatments for MIS-C in an international observational cohort. Analysis of the first 614 patients was previously reported. In this propensity-weighted cohort study, clinical and outcome data from children with suspected or proven MIS-C were collected onto a web-based Research Electronic Data Capture database. After excluding neonates and incomplete or duplicate records, inverse probability weighting was used to compare primary treatments with intravenous immunoglobulin, intravenous immunoglobulin plus glucocorticoids, or glucocorticoids alone, using intravenous immunoglobulin as the reference treatment. Primary outcomes were a composite of inotropic or ventilator support from the second day after treatment initiation, or death, and time to improvement on an ordinal clinical severity scale. Secondary outcomes included treatment escalation, clinical deterioration, fever, and coronary artery aneurysm occurrence and resolution. This study is registered with the ISRCTN registry, ISRCTN69546370. FINDINGS: We enrolled 2101 children (aged 0 months to 19 years) with clinically diagnosed MIS-C from 39 countries between June 14, 2020, and April 25, 2022, and, following exclusions, 2009 patients were included for analysis (median age 8·0 years [IQR 4·2-11·4], 1191 [59·3%] male and 818 [40·7%] female, and 825 [41·1%] White). 680 (33·8%) patients received primary treatment with intravenous immunoglobulin, 698 (34·7%) with intravenous immunoglobulin plus glucocorticoids, 487 (24·2%) with glucocorticoids alone; 59 (2·9%) patients received other combinations, including biologicals, and 85 (4·2%) patients received no immunomodulators. There were no significant differences between treatments for primary outcomes for the 1586 patients with complete baseline and outcome data that were considered for primary analysis. Adjusted odds ratios for ventilation, inotropic support, or death were 1·09 (95% CI 0·75-1·58; corrected p value=1·00) for intravenous immunoglobulin plus glucocorticoids and 0·93 (0·58-1·47; corrected p value=1·00) for glucocorticoids alone, versus intravenous immunoglobulin alone. Adjusted average hazard ratios for time to improvement were 1·04 (95% CI 0·91-1·20; corrected p value=1·00) for intravenous immunoglobulin plus glucocorticoids, and 0·84 (0·70-1·00; corrected p value=0·22) for glucocorticoids alone, versus intravenous immunoglobulin alone. Treatment escalation was less frequent for intravenous immunoglobulin plus glucocorticoids (OR 0·15 [95% CI 0·11-0·20]; p<0·0001) and glucocorticoids alone (0·68 [0·50-0·93]; p=0·014) versus intravenous immunoglobulin alone. Persistent fever (from day 2 onward) was less common with intravenous immunoglobulin plus glucocorticoids compared with either intravenous immunoglobulin alone (OR 0·50 [95% CI 0·38-0·67]; p<0·0001) or glucocorticoids alone (0·63 [0·45-0·88]; p=0·0058). Coronary artery aneurysm occurrence and resolution did not differ significantly between treatment groups. INTERPRETATION: Recovery rates, including occurrence and resolution of coronary artery aneurysms, were similar for primary treatment with intravenous immunoglobulin when compared to glucocorticoids or intravenous immunoglobulin plus glucocorticoids. Initial treatment with glucocorticoids appears to be a safe alternative to immunoglobulin or combined therapy, and might be advantageous in view of the cost and limited availability of intravenous immunoglobulin in many countries. FUNDING: Imperial College London, the European Union's Horizon 2020, Wellcome Trust, the Medical Research Foundation, UK National Institute for Health and Care Research, and National Institutes of Health

Technical Competence of the Future Teacher of Labor Education and Technology as a Basis of Preparedness for Professional Activity

Стаття присвячена теоретичному дослідження актуальності формування технічної компетентності в майбутнього вчителя трудового навчання та технології під час здобуття вищої освіти першого рівня. Сформовану технічну компетентність майбутнього вчителя трудового навчання та технології можна вважати ідеальним результатом професійної підготовки, тобто у здобувача повноцінно опановані знання про конструкційні матеріали (характеристика, критерії, добування, способи обробки), сформовані вміння конструявати вироби, ураховуячи властивості матеріалів, здійснявати економічний обрахунок під час підбору матеріалів для проюкту, вибору способу обробки конструкційних матеріалів із послідовністя технологічних операцій, використовувати вторинні матеріали та набуті творчі навички для праці під час професійної діяльності.The article is devoted to the theoretical study of the relevance of the formation of technical competence in the future teacher of labor training and technology during the first stage of higher education. The formed technical competence of the future teacher of labor training and technology can be considered as an ideal result of professional training, i.e. the applicant has fully mastered knowledge of construction materials (characteristics, criteria, extraction, processing methods), formed skills to design products taking into account the properties of materials, to make economic calculations when selecting materials for the project, choosing the method of processing construction materials with a sequence of technological operations, use secondary materials and acquired creative skills for work during professional activities. Modern higher education works in the direction of finding a solution to the problem of effective formation of competencies in the applicant. This is due to a new stage in the development of education, reviewing and amending the content of education in secondary education institutions to create a favorable educational environment for the development of secondary education, expanding the range of interests and positive interest in learning new things that will form certain life competencies. The national development of education in Ukraine is aimed at implementing the project “New Ukrainian School”, which will fully create conditions for the educational process in which children can express themselves creatively as individuals and form key competencies for dynamic integration of knowledge, skills, acquired skills to be able to evaluate other views, values and personal qualities, which will be the basis for successful further educational activities. The future teacher must be a professional in his field, have developed competencies, experience and pedagogical skills, i.e. be ready to form key competencies in the applicant for secondary education