Selforganized 3-band structure of the doped fermionic Ising spin glass

The fermionic Ising spin glass is analyzed for arbitrary filling and for all temperatures. A selforganized 3-band structure of the model is obtained in the magnetically ordered phase. Deviation from half filling generates a central nonmagnetic band, which becomes sharply separated at T=0 by (pseudo)gaps from upper and lower magnetic bands. Replica symmetry breaking effects are derived for several observables and correlations. They determine the shape of the 3-band DoS, and, for given chemical potential, influence the fermion filling strongly in the low temperature regime.Comment: 13 page

Spin - glass transition in Kondo lattice with quenched disorder

We use the Popov-Fedotov representation of spin operators to construct an effective action for a Kondo lattice model with quenched disorder at finite temperatures. We study the competition between the Kondo effect and frozen spin order in Ising-like spin glass. We present the derivation of new mean-field equations for the spin-glass order parameter and analyze the effects of screening of localized spins by conduction electrons on the spin-glass phase transition.Comment: 6 pages, jetpl style included, to appear in JETP Letter

Bound hole states in a ferromagnetic (Ga,Mn)As environment

A numerical technique is developed to solve the Luttinger-Kohn equation for impurity states directly in k-space and is applied to calculate bound hole wave functions in a ferromagnetic (Ga,Mn)As host. The rich properties of the band structure of an arbitrarily strained, ferromagnetic zinc-blende semiconductor yields various features which have direct impact on the detailed shape of a valence band hole bound to an active impurity. The role of strain is discussed on the basis of explicit calculations of bound hole states.Comment: 9 pages, 10 figure

What if? Counterfactual Trump and the western response to the war in Ukraine

Because of his personality, had Donald Trump won the 2020 election the remarkable and unexpected united response by NATO allies to the February 2022 Russian invasion of Ukraine would not have happened. Relying on leader personality research in foreign policy, we demonstrate this by using the counterfactual method of analysis. Specifying key differences between Biden's and Trump's personalities in terms of their experiences, traits and beliefs, we explicitly show that president Trump would have been very unlikely to share US intelligence, rally NATO allies in support of Ukraine or challenge Vladimir Putin. In contrast, these responses fit very well with Joe Biden's personality. We first present counterfactual analysis as a method before comparing Biden and Trump along personality characteristics known to significantly influence foreign-policy decisions. Through our case-study, we demonstrate the value of using systematic and theoretically grounded counterfactual methods for assessing the importance of individual differences between leaders and emphasizing their impact on international affairs.Publisher PDFPeer reviewe

Role theory, foreign policy, and the social construction of sovereignty:Brexit stage right

The publication of this article was funded by Chemnitz University of Technology; Kai Oppermann is this article's corresponding author.The international roles states play in world politics are bound up with the ways in which sovereignty is constructed within the international system. While scholarship on sovereignty has recognized its social construction, and role research emphasizes social interactions as shaping roles and role behaviors, little work has explored the relationship between sovereignty and roles. Linking roles and sovereignty offers a distinct perspective on the social construction of sovereignty, providing a broad conception of socialization, emphasizing agency, and bridging domestic politics and international relations. We develop the concept of a “sovereignty–role nexus” through an examination of Brexit, revealing, through processes of role contestation and role socialization, multiple and competing constructions of the nature and value of sovereignty. While Brexit is unique, we suggest that these dynamics will affect other cases where states face role changes linked to sovereignty concerns.Publisher PDFPeer reviewe

Medium- and short-chain dehydrogenase/reductase gene and protein families: The SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymes

Short-chain dehydrogenases/reductases (SDRs) constitute a large family of NAD(P)(H)-dependent oxidoreductases, sharing sequence motifs and displaying similar mechanisms. SDR enzymes have critical roles in lipid, amino acid, carbohydrate, cofactor, hormone and xenobiotic metabolism as well as in redox sensor mechanisms. Sequence identities are low, and the most conserved feature is an α/β folding pattern with a central beta sheet flanked by 2–3 α-helices from each side, thus a classical Rossmannfold motif for nucleotide binding. The conservation of this element and an active site, often with an Asn-Ser-Tyr-Lys tetrad, provides a platform for enzymatic activities encompassing several EC classes, including oxidoreductases, epimerases and lyases. The common mechanism is an underlying hydride and proton transfer involving the nicotinamide and typically an active site tyrosine residue, whereas substrate specificity is determined by a variable C-terminal segment. Relationships exist with bacterial haloalcohol dehalogenases, which lack cofactor binding but have the active site architecture, emphasizing the versatility of the basic fold in also generating hydride transfer-independent lyases. The conserved fold and nucleotide binding emphasize the role of SDRs as scaffolds for an NAD(P)(H) redox sensor system, of importance to control metabolic routes, transcription and signalling

Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding

The MAGE (melanoma associated antigen) protein family are tumour-associated proteins normally present only in reproductive tissues such as germ cells of the testis. The human genome encodes over 60 MAGE genes of which one class (containing MAGE-A3 and MAGE-A4) are exclusively expressed in tumours, making them an attractive target for the development of targeted and immunotherapeutic cancer treatments. Some MAGE proteins are thought to play an active role in driving cancer, modulating the activity of E3 ubiquitin ligases on targets related to apoptosis. Here we determined the crystal structures of MAGE- A3 and MAGE-A4. Both proteins crystallized with a terminal peptide bound in a deep cleft between two tandem-arranged winged helix domains. MAGE-A3 (but not MAGE-A4), is pre- dominantly dimeric in solution. Comparison of MAGE-A3 and MAGE-A3 with a structure of an effector-bound MAGE-G1 suggests that a major conformational rearrangement is required for binding, and that this conformational plasticity may be targeted by allosteric binders

Design and compilation of an object-oriented macroprogramming language for wireless sensor networks

open5siWireless sensor network (WSN) programming is still largely performed by experts in a node-centric way using low-level languages such as C. Although numerous higher-level abstractions exist, each simplifying a specific aspect of distributed programming, real applications often require to combine multiple abstractions into a single program. Using current programming frameworks, this represents a difficult task. In previous work, we therefore defined a conceptual framework that facilitates abstraction composition by defining sound compositional rules among few fundamental abstraction categories. The framework is extensible: programmers can add new abstractions within the boundaries determined by the compositional rules. In this paper we describe the design of a language - called MPL - that instantiates this conceptual framework. To support the extensible nature of the framework, the language is object-oriented, which allows programmers to add new abstractions by inheriting from existing classes that implement predefined interfaces. We modeled the syntax after Java, to make it more palatable to inexperienced embedded programmers. Compared to Java, we modified the language to enable efficient execution on WSN devices. We designed and implemented a compiler that translates MPL language into executable C code, which spares the overhead of a virtual machine. By comparing MPL implementations against functionally-equivalent Contiki/C implementations of several benchmark applications, we determined that the performance overhead of MPL is limited, and yet the programming task is simplified.openOppermann, Felix Jonathan; Römer, Kay; Mottola, Luca; Picco, Gian Pietro; Gaglione, AndreaOppermann, Felix Jonathan; Römer, Kay; Mottola, Luca; Picco, Gian Pietro; Gaglione, Andre

Pseudoseptic Arthritis: A Case Series and Review of the Literature

Purpose. Pseudoseptic arthritis is an acute inflammatory monoarthritis with a sterile synovial gram stain and culture. Pseudoseptic arthritis has been previously described in the literature in a variety of settings including rheumatoid arthritis and microcrystalline disease. Despite pseudoseptic arthritis being a described entity, there is little published data on this topic with no published reports since 1992. Methods. This paper was a retrospective chart review over a 20-year period that identified all rheumatology inpatient consultations at our tertiary rural hospital for pseudoseptic arthritis. Results. We identified 10 patients with pseudoseptic arthritis and presented 5 of those cases in this paper. Majority of these patients had known autoimmune inflammatory arthritis or microcrystalline inflammatory arthritis. Conclusion. Pseudoseptic arthritis is a syndrome that should be in the differential diagnosis with patients with long standing inflammatory condition who present with an acute monoarthritis with no known bacterial source for septic arthritis

Metallic spin glasses

Recent work on the zero temperature phases and phase transitions of strongly random electronic system is reviewed. The transition between the spin glass and quantum paramagnet is examined, for both metallic and insulating systems. Insight gained from the solution of infinite range models leads to a quantum field theory for the transition between a metallic quantum paramagnetic and a metallic spin glass. The finite temperature phase diagram is described and crossover functions are computed in mean field theory. A study of fluctuations about mean field leads to the formulation of scaling hypotheses.Comment: Contribution to the Proceedings of the ITP Santa Barbara conference on Non-Fermi liquids, 25 pages, requires IOP style file