22 research outputs found
Cinnamic acid induces apoptotic cell death and cytoskeleton disruption in human melanoma cells
A critical review of the literature to conduct a toxicity assessment for oral exposure to methyl salicylate
Eocene bipolar glaciation associated with global carbon cycle changes.
The transition from the extreme global warmth of the early Eocene 'greenhouse' climate approx55 million years ago to the present glaciated state is one of the most prominent changes in Earth's climatic evolution. It is widely accepted that large ice sheets first appeared on Antarctica approx34 million years ago, coincident with decreasing atmospheric carbon dioxide concentrations and a deepening of the calcite compensation depth in the world's oceans, and that glaciation in the Northern Hemisphere began much later, between 10 and 6 million years ago. Here we present records of sediment and foraminiferal geochemistry covering the greenhouse–icehouse climate transition. We report evidence for synchronous deepening and subsequent oscillations in the calcite compensation depth in the tropical Pacific and South Atlantic oceans from approx42 million years ago, with a permanent deepening 34 million years ago. The most prominent variations in the calcite compensation depth coincide with changes in seawater oxygen isotope ratios of up to 1.5 per mil, suggesting a lowering of global sea level through significant storage of ice in both hemispheres by at least 100 to 125 metres. Variations in benthic carbon isotope ratios of up to approx1.4 per mil occurred at the same time, indicating large changes in carbon cycling. We suggest that the greenhouse–icehouse transition was closely coupled to the evolution of atmospheric carbon dioxide, and that negative carbon cycle feedbacks may have prevented the permanent establishment of large ice sheets earlier than 34 million years ago
The motion decoupled delivery system: A new deployment system for downhole tools is tested at the New Jersey margin
The Motion Decoupled Hydraulic Delivery System (MDHDS) is a new downhole tool delivery system that is deployed by wireline and uses drillstring pressure to advance a penetrometer (or other downhole tool) into the formation at the bottom of offshore boreholes. After hydraulic deployment of the penetrometer, it is completely decoupled from the BHA; this eliminates the adverse effects of ship heave. We tested the MDHDS at Site U1402 (the location of Site 1073, ODP Leg 174A), offshore New Jersey, during two days of ship time during Integrated Ocean Drilling Program (IODP) Expedition 342. In one deployment we emplaced a penetrometer successfully and documented that it was decoupled from drillstring movement. Based on this successful field test, the MDHDS has been certified by the U.S. Implementing Organization (USIO) for shipboard use. The MDHDS will replace the previous deployment system, the Colletted Delivery System. The MDHDS is an IODP-funded engineering development led by The University of Texas at Austin, in conjunction with the USIO and Stress Engineering Services. This sea trial was the culmination of a seven-year development effort that included extensive engineering design and fabrication
Zingerone Mitigates Carrageenan-Induced Inflammation Through Antioxidant and Anti-inflammatory Activities
Diacetyl and 2,3-pentanedione exposures associated with cigarette smoking: implications for risk assessment of food and flavoring workers
Paleogeography and tectono-stratigraphy of carboniferous-Permian and Triassic "Karoo-like" sequences of the congo basin
International audienceThe Congo Basin is a large Phanerozoic sedimentary basin with up to 3–6 km of Carboniferous to Triassic sequences, comparable to those of the Karoo Basins of southern Gondwana. Here, we present a substantially revised stratigraphy for the Congo Basin, based on new field observations, seismic and borehole data, together with paleontology and new geochronology. In the center of the basin, the deepest boreholes intercept 3 to 4 km thick successions of conglomerates and red sandstones that overlie carbonate rocks, which correlate to deformed upper Neoproterozoic (Pan African) platform sequences extending beyond the Congo Basin into the Pan African orogenic zones (e.g. the West Congolian Group). The overlying sequences are dated biostratigraphically to be Carboniferous-Permian (the Lukuga Group) and Triassic (the Haute Lueki Group) in age. A regional erosion surface separates these two groups, possibly related to late Paleozoic intracontinental deformation associated with the Mauritanian-Variscan and Cape-de la Ventana orogens flanking the northwestern and southern margins of Gondwana, respectively. This change in basin paleogeography is consistent with detrital zircons dated from these sequences that suggest the ca. 1.4 Ga Kibaran Belt along the eastern margin of the Congo Basin stopped acting as a major source during the early Mesozoic