Hi Doppelgänger: Towards Detecting Manipulation in News Comments

Public opinion manipulation is a serious threat to society, potentially influencing elections and the political situation even in established democracies. The prevalence of online media and the opportunity for users to express opinions in comments magnifies the problem. Governments, organizations, and companies can exploit this situation for biasing opinions. Typically, they deploy a large number of pseudonyms to create an impression of a crowd that supports specific opinions. Side channel information (such as IP addresses or identities of browsers) often allows a reliable detection of pseudonyms managed by a single person. However, while spoofing and anonymizing data that links these accounts is simple, a linking without is very challenging. In this paper, we evaluate whether stylometric features allow a detection of such doppelgängers within comment sections on news articles. To this end, we adapt a state-of-the-art doppelgänger detector to work on small texts (such as comments) and apply it on three popular news sites in two languages. Our results reveal that detecting potential doppelgängers based on linguistics is a promising approach even when no reliable side channel information is available. Preliminary results following an application in the wild shows indications for doppelgängers in real world data sets

Fine-tuning of whispering gallery modes in on-chip silica microdisk resonators within a full spectral range

We investigate an efficient method for fine-tuning whispering gallery mode resonances in disk-type silica microresonators to reach an arbitrary frequency within the free spectral range of the system. This method is based on a post-production hydrofluoric acid etching process to precisely resize the radius of such microresonators. We show the effectiveness of this approach by tuning their resonance frequency within 10 GHz of specific hydrogen cyanide reference lines (P16, P18). This technique allows for simple and exact matching of narrow-linewidth lasers or spectroscopic lines with the high-Q resonances of on-chip silica microresonators. (C) 2013 American Institute of Physics. (http://dx.doi.org/10.1063/1.4789755

Prospectus, September 13, 1978

ELECTION DAYS ARE HERE!; Students get refund from hungry Canteen machines; Recipes for college students; CPR saves lives; Advertising Policy; PC band formed; \u27Lost in a masquerade\u27 Benson creates ecstasy; Creative writers receive assistance; Health issues program new WPCD addition; Operetta to begin tomorrow; Shaker photograph exhibition; Student Elections -- Today!; Cadaver lab is added; Apathetic turnout; Poet contest sponsored; Volleyball clinic held Sept. 9; Meeting Sept. 26 for cheerleaders; WPCD\u27s Top 15 For The Week Of Sept. 11; German club to begin activities; Classifieds; Cimmeron review \u27mediocre\u27; Thought food offered for older adults; Student Activities-\u2778; Doehring keeps on truckin\u27; Coach Jim Reed gets many players; Klems wins first Freddy contest; Cooper recruits well; Williams has busy year ahead of him; Fast Freddy Contest; Cross Country Schedulehttps://spark.parkland.edu/prospectus_1978/1012/thumbnail.jp

Macrophage miR-210 induction and metabolic reprogramming in response to pathogen interaction boost life-threatening inflammation

Unbalanced immune responses to pathogens can be life-threatening although the underlying regulatory mechanisms remain unknown. Here, we show a hypoxia-inducible factor 1α–dependent microRNA (miR)–210 up-regulation in monocytes and macrophages upon pathogen interaction. MiR-210 knockout in the hematopoietic lineage or in monocytes/macrophages mitigated the symptoms of endotoxemia, bacteremia, sepsis, and parasitosis, limiting the cytokine storm, organ damage/dysfunction, pathogen spreading, and lethality. Similarly, pharmacologic miR-210 inhibition improved the survival of septic mice. Mechanistically, miR-210 induction in activated macrophages supported a switch toward a proinflammatory state by lessening mitochondria respiration in favor of glycolysis, partly achieved by downmodulating the iron-sulfur cluster assembly enzyme ISCU. In humans, augmented miR-210 levels in circulating monocytes correlated with the incidence of sepsis, while serum levels of monocyte/macrophage-derived miR-210 were associated with sepsis mortality. Together, our data identify miR-210 as a fine-tuning regulator of macrophage metabolism and inflammatory responses, suggesting miR-210–based therapeutic and diagnostic strategies

Hot, rocky and warm, puffy super-Earths orbiting TOI-402 (HD 15337)

Context: The Transiting Exoplanet Survey Satellite (TESS) is revolutionising the search for planets orbiting bright and nearby stars. In sectors 3 and 4, TESS observed TOI-402 (TIC-120896927), a bright V = 9.1 K1 dwarf also known as HD 15337, and found two transiting signals with periods of 4.76 and 17.18 days and radii of 1.90 and 2.21 R⊕, respectively. This star was observed prior to the TESS detection as part of the radial-velocity (RV) search for planets using the HARPS spectrometer, and 85 precise RV measurements were obtained before the launch of TESS over a period of 14 yr. Aims: In this paper, we analyse the HARPS RV measurements in hand to confirm the planetary nature of these two signals. Methods: HD 15337 happens to present a stellar activity level similar to the Sun, with a magnetic cycle of similar amplitude and RV measurements that are affected by stellar activity. By modelling this stellar activity in the HARPS radial velocities using a linear dependence with the calcium activity index log(RHK′), we are able, with a periodogram approach, to confirm the periods and the planetary nature of TOI-402.01 and TOI-402.02. We then derive robust estimates from the HARPS RVs for the orbital parameters of these two planets by modelling stellar activity with a Gaussian process and using the marginalised posterior probability density functions obtained from our analysis of TESS photometry for the orbital period and time of transit. Results: By modelling TESS photometry and the stellar host characteristics, we find that TOI-402.01 and TOI-402.02 have periods of 4.75642 ± 0.00021 and 17.1784 ± 0.0016 days and radii of 1.70 ± 0.06 and 2.52 ± 0.11 R⊕ (precision 3.6 and 4.2%), respectively. By analysing the HARPS RV measurements, we find that those planets are both super-Earths with masses of 7.20 ± 0.81 and 8.79 ± 1.68 M⊕ (precision 11.3 and 19.1%), and small eccentricities compatible with zero at 2σ. Conclusions: Although having rather similar masses, the radii of these two planets are very different, putting them on different sides of the radius gap. By studying the temporal evolution under X-ray and UV (XUV) driven atmospheric escape of the TOI-402 planetary system, we confirm, under the given assumptions, that photo-evaporation is a plausible explanation for this radius difference. Those two planets, being in the same system and therefore being in the same irradiation environment are therefore extremely useful for comparative exoplanetology across the evaporation valley and thus bring constraints on the mechanisms responsible for the radius gap

Primary prophylaxis of bacterial infections and Pneumocystis jirovecii pneumonia in patients with hematologic malignancies and solid tumors: 2020 updated guidelines of the Infectious Diseases Working Party of the German Society of Hematology and Medical Oncology (AGIHO/DGHO)

Hematologic and oncologic patients with chemo- or immunotherapy-related immunosuppression are at substantial risk for bacterial infections and Pneumocystis jirovecii pneumonia (PcP). As bacterial resistances are increasing worldwide and new research reshapes our understanding of the interactions between the human host and bacterial commensals, administration of antibacterial prophylaxis has become a matter of discussion. This guideline constitutes an update of the 2013 published guideline of the Infectious Diseases Working Party (AGIHO) of the German Society for Hematology and Medical Oncology (DGHO). It gives an overview about current strategies for antibacterial prophylaxis in cancer patients while taking into account the impact of antibacterial prophylaxis on the human microbiome and resistance development. Current literature published from January 2012 to August 2020 was searched and evidence-based recommendations were developed by an expert panel. All recommendations were discussed and approved in a consensus conference of the AGIHO prior to publication. As a result, we present a comprehensive update and extension of our guideline for antibacterial and PcP prophylaxis in cancer patients