Examining the segment retention problem for the “Group Satellite” case

The purpose of this work is to determine how well, criteria designed to help the selection of the adequate number of market segments, perform in recovering small niche segments, in mixture regressions of normal data, with experimental data. The simulation experiment compares several segment retention criteria, including information criteria and classification-based criteria. We also address the impact of distributional misspecification on segment retention criteria success rates. This study shows that Akaike’s Information criterion with penalty factors of 3 and 4, rather than the traditional value of 2, are the best segment retention criteria to use in recovering small niche segments. Although these criteria were designed for the specific context of mixture models, they are rarely applied in the marketing literature.Information criteria; Latent Class Segmentation.

Effects of personal, social and environmental factors on physical activity behavior among adults

Despite the guidelines and the well-recognized benefits of regular physical activity, there is evidence that a large number of people is still reported to be inactive. Therefore, the need for interventions that can promote a healthier behavior has increased. As an understanding of the determinants of physical activity behavior by health professionals is an important prerequisite to designing effective interventions, studies on the identification of the determinants of physical activity are warranted. The purpose of this work is to review and update the research on determinants underlying physical activity behaviour in adults and to provide an overview of physical activity patterns among adult populations. The findings highlight the need for an evaluation of the interactive effects of psychosocial, cultural, environmental and public policy influences on physical activity forging a trans-disciplinary paradigm

Dimensions of football stadium and museum tour experiences: The case of Europe’s most valuable brands

In the context of football’s globalisation, some of the most important football clubs (FCs) can currently be classified as ‘entertainment multinationals’. Sport hospitality provides opportunities to maximise club stadiums’ use so that they can increase clubs’ annual turnover and function as branding platforms. This study sought to identify the main narratives shared online about—and the dimensions of—visitors’ experiences with top football brands in stadium tours. The data collected for this research comprised 400 text reviews for 10 European FCs’ stadiums (i.e., 4000 reviews) written by visitors in the post-experience phase. Content analysis of these Web reviews was conducted using Leximancer software. The results confirm the existence of 15 themes: fan, tour, stadium, team, museum, room, staff, game, (best) place, ticket, seating, recommend(ation), food, shop and attraction. Most researchers have examined stadium tours from a supply-side perspective. The present study’s aim was, therefore, to contribute to the existing literature by analysing stadium tours’ dimensions from the visitors’ point of view. Stadium tours and museum visits are important sources of revenue that contribute to FCs’ economic sustainability. Offering outstanding customer experiences is thus of utmost importance to maximise club stadiums’ usage and strengthen fans’ engagement.info:eu-repo/semantics/publishedVersio

The psychological determinants of the green consumer

Nos últimos anos tem-se verificado uma preocupação crescente em relação à temática ambiental na população em geral, nos consumidores, nos governos, nas empresas e nos investigadores. Efetivamente, os consumidores têm consciência de que o seu comportamento é suscetível de influenciar o meio ambiente, começando a ter uma maior preocupação aquando da escolha dos produtos que adquirem e consomem. Os governos procuram promover políticas de sustentabilidade ambiental, e as empresas reconhecem que a adoção de um posicionamento socialmente responsável e a oferta de produtos verdes suscetíveis de responder às necessidades do consumidor são aspetos chave para o desenvolvimento e manutenção de uma vantagem competitiva. Neste contexto, o presente trabalho teve como objetivo estudar os determinantes do comportamento de compra de produtos verdes, com base no quadro teórico da Teoria do Comportamento Planeado. Considerando uma amostra de colaboradores de uma empresa em Portugal com cobertura geográfica nacional, concluiu-se que as variáveis atitude, norma subjetiva e controlo percebido têm influência na intenção comportamental, de compra de produtos verdes.info:eu-repo/semantics/publishedVersio

In vivo and in vitro effects of RAD001 on bladder cancer

Objective: To evaluate the influence of Everolimus (RAD001) on chemically induced urothelial lesions in mice and its influence on in vitro human bladder cancer cell lines. Methods: ICR male mice were given N-butyl-N-(4-hydroxybutyl) nitrosamine in drinking water for a period of 12 weeks. Subsequently, RAD001 was administered via oral gavage, for 6 weeks. At the end of the experiment, all the animals were sacrificed and tumor development was determined by means of histopathologic evaluation; mammalian target of rapamycin (mTOR) expressivity was evaluated by immunohistochemistry. Three human bladder cancer cell lines (T24, HT1376, and 5637) were treated using a range of RAD001 concentrations. MTT assay, terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL), and flow cytometry were used to assess cell proliferation, apoptosis index, and cell cycle analysis, respectively. Immunoblotting analysis of 3 cell line extracts using mTOR and Akt antibodies was performed in order to study the expression of Akt and mTOR proteins and their phosphorylated forms. Results: The incidence of urothelial lesions in animals treated with RAD001 was similar to those animals not treated. RAD001 did not block T24 and HT1376 cell proliferation or induce apoptosis. A reduction in cell proliferation rate and therefore G0/G1 phase arrest, as well as a statistically significant induction of apoptosis (P 0.001), was only observed in the 5637 cell line. Conclusion: RAD001 seems not to have a significant effect on chemically induced murine bladder tumors. The effect of RAD001 on tumor proliferation and apoptosis was achieved only in superficial derived bladder cancer cell line, no effect was observed in invasive cell lines

Potencial leiteiro de animais da raça Pantaneira na região do Alto Pantanal do Mato Grosso do Sul.

Este trabalho teve como objetivo determinar o período de lactação e uma composição físico-química do leite das vacas da raça panteira. ABSTRACT: The Pantaneira breed is in danger of extinction. Due to the lack of scientific information on the Pantanal milk potential, this work had the objective of determining the lactation period and a physical-chemical composition of the milk of cows in second order of parturition. The animals were managed in a pasture system rotated in mombaça grass (Panicum maximum) and individually supplemented with concentrate. The milking was performed mechanically twice a day and the milk weighed daily. The physical-chemical characteristics of the milk were evaluated by the ultrasound method and the lactation curves were estimated using the univariate parameter. The average milk yield was 5.34kg/milk/ day and the fat, protein, lactose and total non-fat solids contents were 5.3, 3.7, 6.0 and 10.7%, respectively. Lactation of the cows in second order of calving ended naturally at 180 days and the peak of milk production was reached between 51 and 60 days. Furthermore, there was no difference in milk composition in the different lactation periods

Engolo and Capoeira. From Ethnic to Diasporic Combat Games in the Southern Atlantic

This article provides a re-examination of the main Afrocentric narrative of capoeira origins, the engolo or ‘Zebra Dance’, in light of historical primary sources and new ethnographic evidence gathered during fieldwork in south-west Angola. By examining engolo’s bodily techniques, its socio-historical context and cultural meanings, the piece emphasises its insertion into a pastoral lifestyle and highlights the relatively narrow ethnic character of the practice in Angola. This analysis and the comparison with capoeira helps us to develop certain hypotheses about the formation, migration, and re-invention of diasporic combat games between southern Angola and coastal Brazil, and more broadly, to increase our understanding of how African cultures spread across the southern Atlantic

Arqueologia e história indígena no Pantanal

O artigo apresenta uma síntese dos dados arqueológicos sobre o Pantanal e o seu entorno, principalmente em Mato Grosso e Mato Grosso do Sul. Elaborado com base na noção de arqueologia como história indígena de longa duração, o artigo considera as trajetórias de estabelecimento e consolidação territorial da ocupação indígena regional, os processos de formação da configuração etnográfica encontrada pelos europeus e os impactos do colonialismo. O principal objetivo consiste em mostrar que a diversidade cultural característica do cenário etnográfico pantaneiro está associada à dinâmica histórica e cultural da ocupação indígena desde períodos anteriores à chegada dos conquistadores e colonizadores de origem europeia.The article presents an overview of the archaeological data on the Pantanal and its surrounding areas, mainly in Mato Grosso and Mato Grosso do Sul. Prepared based on the notion of archeology as long term indigenous history, the article considers the trajectories of territorial establishment and consolidation of the regional indigenous occupation, the formation processes of ethnographic setting found by Europeans and the impact of colonialism. The main objective is to show that cultural diversity characteristic of the Pantanal ethnographic scenario is associated with historical and cultural dynamics of indigenous occupation from periods prior to the arrival of the conquistadors and settlers of European origin

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality