Weather and resource information as tools for dealing with farmer–pastoralist conflicts in the Sahel

Conflicts between pastoralists and farmers in the Sahel mainly arise from competition over land and water resources or because of livestock damage to crops. Rather than being linked to larger environmental change processes such as climate change, conflicts are often caused by inappropriate zoning of land, governance and unequal power relations between stakeholders. However, conflicts may be affected by more short-term weather and resource information that guide mobility of pastoralists. In this paper, we therefore explore if improved weather and resource information and improvement in its communication could prevent conflicts or reduce their severity. Based on a survey of key stakeholders involved in dissemination of weather and resource information and studies on pastoral access to and use of information, we conclude that improved information may both reduce and increase the level of conflict, depending on the context. Communication of information will need to go beyond just the weather and resource information and also include the multiple options for herd movements as well as providing information on herd crowding and potential conflict areas

Governing for ecosystem health and human wellbeing

Governance arrangements and processes influence access to and benefits from ecosystem services, and therefore the potential for ecosystem services to alleviate poverty. Governance also then influences the health of ecosystems. This chapter learns from decades of governance-related research to identify how to make ecosystem governance more effectively ‘pro-poor’. It is informed by a systematic mapping of literature related to governance of ecosystem services and renewable natural resources for improved wellbeing and poverty alleviation, expert interviews and a workshop with government and non-government actors across a range of sectors from both North and South. The chapter is organised around the concept of trade-offs, considering first ecosystem-focused approaches, then rights-based approaches and lastly, participatory approaches to governance. The chapter further addresses the relevance of scale and multiple administrative levels (multi-level governance) and the importance of informal, or socially embedded, institutions. The chapter concludes that there is no single governance approach that can definitively deliver on improved ecosystem health and human wellbeing, that trade-offs are inevitable and governance is therefore an inherently political process

What Is New for an Old Molecule? Systematic Review and Recommendations on the Use of Resveratrol

BACKGROUND: Resveratrol is a natural compound suggested to have beneficial health effects. However, people are consuming resveratrol for this reason without having the adequate scientific evidence for its effects in humans. Therefore, scientific valid recommendations concerning the human intake of resveratrol based on available published scientific data are necessary. Such recommendations were formulated after the Resveratrol 2010 conference, held in September 2010 in Helsingør, Denmark. METHODOLOGY: Literature search in databases as PUBMED and ISI Web of Science in combination with manual search was used to answer the following five questions: (1)Can resveratrol be recommended in the prevention or treatment of human diseases?; (2)Are there observed side effects caused by the intake of resveratrol in humans?; (3)What is the relevant dose of resveratrol?; (4)What valid data are available regarding an effect in various species of experimental animals?; (5)Which relevant (overall) mechanisms of action of resveratrol have been documented? CONCLUSIONS/SIGNIFICANCE: The overall conclusion is that the published evidence is not sufficiently strong to justify a recommendation for the administration of resveratrol to humans, beyond the dose which can be obtained from dietary sources. On the other hand, animal data are promising in prevention of various cancer types, coronary heart diseases and diabetes which strongly indicate the need for human clinical trials. Finally, we suggest directions for future research in resveratrol regarding its mechanism of action and its safety and toxicology in human subjects

Challenges in Analyzing the Biological Effects of Resveratrol

The suggested health effects (e.g., disease prevention) of dietary bioactive compounds such as resveratrol are challenging to prove in comparison to man-made drugs developed for therapeutic purposes. Dietary bioactive compounds have multiple cellular targets and therefore have a variety of biological effects. Extrapolating the biological effects of dietary compounds from in vitro and in vivo animal experiments to humans may lead to over- or under-estimation of the effect and role of these compounds. The present paper will discuss a few of these challenges and suggest directions for future research. Questions we address include: (1) Is the combinatorial effect of resveratrol and other compounds real? (2) What are the real and relevant doses of resveratrol after administration? and (3) Is it possible to estimate the preventive effect of resveratrol by clinical trials using standard experimental designs? The examples concerning resveratrol taken from the scientific literature are mainly from 2010 and later. The challenges pointed out in this review are similar to most naturally occurring bioactive compounds