Local Development and Social Capital: The Case of Sotkamo

The paper discusses the role of social capital in the dramatic structural change that has taken place in the rural municipality of Sotkamo in north-eastern Finland. The main approach of this study is to observe the formation and use of social capital in important local events. Earlier definitions of local development have been based on factors such as natural resources, labour force, machines and tools, technology, knowledge and skills. The explanation based on social capital focuses on factors which increase and improve co-operation. Important issues of social capital are the existing rules of behaviour, the networks mediating these rules, and the trust amongst members of society that these rules are respected. In the case of Sotkamo the change has been the rise of tourism. Simultaneously this has meant the rise of Vuokatti as the central place in regional and local development. The paper is based on a questionnaire study and key-person interviews in Sotkamo. The paper discusses the following themes: What kind of actors and networks are participating in local development? Which actors are regarded as trustworthy in local development? What kinds of changes have occurred in the local identity and image? What kinds of struggles and coalitions of local power can be recognised? Results are analysed in the framework of social capital and local development. The study concludes that 'balanced' local development may take place, if the locality has the capacity of building networks that can meet the challenges of the future. Such networks should unite actors using both traditional local resources and new resources from outside of the locality. An important challenge is to balance the demands of economic restructuring and those of local community cohesion. This paper is based on the Finnish national study RESTRIM (Restructuring in Marginal Rural Areas: the role of social capital in rural development), a project that is funded by the European Union (for more, see http://www.abdn.ac.uk/arkleton/RESTRIM/).

High alveolar nitric oxide is associated with steeper lung function decline in foundry workers

Occupational dust exposure induces inflammatory responses that often precede the onset of clinical disease. Inflammation in the peripheral part of the lung can be demonstrated by measuring the alveolar NO concentration (CANO) in exhaled breath. The aim of the study was to assess whether cumulative dust exposure affects the change in CANO during follow-up and whether baseline CANO can predict an impairment in lung function during follow-up in foundry workers. We examined 74 dust-exposed and 42 nonexposed foundry workers and measured CANO and lung function at baseline and after 7 years of follow-up. An increase in CANO during the follow-up period was positively associated with cumulative dust exposure in foundry work (p= 0.035). Furthermore, a higher baseline CANO was associated with an accelerated decline in the forced vital capacity (FVC) during the follow-up period (absolute decrease in FVCp= 0.021, relative decrease in FVCp= 0.017). Higher cumulative dust exposure in foundry work is associated with a greater increase in CANO during follow-up, suggesting ongoing pulmonary inflammation in these subjects. Importantly, a high baseline CANO is associated with an accelerated decline in lung function, suggesting that CANO measurements might serve as a screening tool for high-risk workers.acceptedVersionPeer reviewe

Miksi ammattitaudit vähenevät?: Mitkä asiat selittävät alueelliset erot ammattitautien määrissä Suomessa ja kokonaismäärän muutokset?

Ammattitaudit kertovat työoloista ja siksi niiden lukumäärien muutokset ovat kiinnostavia. Rekisteriin ilmoitettujen tapausmäärien vaihteluiden syyt osoittautuivat kiinnostaviksi ja moninaisiksi. Suurimpia vaikuttajia olivat kuitenkin yhteiskunnan ja yritysten panostukset työolojen kehittämiseen ja työterveyshuoltoon. Ammattitaudit ja ammattitautiepäilyt kertyvät Työperäisten sairauksien rekisteriin varsin kattavasti. Raportissa on ehdotuksia rekisterin kehittämiseksi avoimempaan ja analyyttisempään suuntaan, jotta työsuojelu- ja työterveystyö tehostuisivat entisestään

Työterveysyhteistyöllä vaikuttavuutta työkyvyn tukeen

Tavoitteellinen työturvallisuuden, terveyden ja työkyvyn edistämiseen tähtäävä toiminta luo mahdollisuuden työntekijöiden parempaan terveyteen ja työkykyyn. Toiminnan avulla on saavutettavissa myös myönteisiä taloudellisia vaikutuksia. Samalla luodaan hyvää ilmapiiriä sekä lisätään luottamusta ja työmotivaatiota. Tavoitteet toteutuvat työpaikan, työterveyshuollon ja tarvittavien muiden toimijoiden yhteistyöllä. Onnistunut yhteistyö lisää keskinäistä luottamusta

Asbestos-related pleural and lung fibrosis in patients with retroperitoneal fibrosis

<p>Abstract</p> <p>Background</p> <p>Retroperitoneal fibrosis (RPF) is a rare fibroinflammatory disease that leads to hydronephrosis and renal failure. In a case-control study, we have recently shown that asbestos exposure was the most important risk factor for RPF in the Finnish population. The aim of this study was to evaluate the relation of asbestos exposure to radiologically confirmed lung and pleural fibrosis among patients with RPF.</p> <p>Methods</p> <p>Chest high-resolution computed tomography (HRCT) was performed on 16 unexposed and 22 asbestos-exposed RPF patients and 18 asbestos-exposed controls. Parietal pleural plaques (PPP), diffuse pleural thickening (DPT) and parenchymal fibrosis were scored separately.</p> <p>Results</p> <p>Most of the asbestos-exposed RPF patients and half of the asbestos-exposed controls had bilateral PPP, but only a few had lung fibrosis. Minor bilateral plaques were detected in two of the unexposed RPF patients, and none had lung fibrosis. DPT was most frequent and thickest in the asbestos-exposed RPF-patients. In three asbestos-exposed patients with RPF we observed exceptionally large pleural masses that were located anteriorly in the pleural space and continued into the anterior mediastinum.</p> <p>Asbestos exposure was associated with DPT in comparisons between RPF patients and controls (case-control analysis) as well as among RPF patients (case-case analysis).</p> <p>Conclusion</p> <p>The most distinctive feature of the asbestos-exposed RPF patients was a thick DPT. An asbestos-related pleural finding was common in the asbestos-exposed RPF patients, but only a few of these patients had parenchymal lung fibrosis. RPF without asbestos exposure was not associated with pleural or lung fibrosis. The findings suggest a shared etiology for RPF and pleural fibrosis and furthermore possibly a similar pathogenetic mechanisms.</p

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

High blood pressure is a major risk factor for cardiovascular disease and premature death. However, there is limited knowledge on specific causal genes and pathways. To better understand the genetics of blood pressure, we genotyped 242,296 rare, low-frequency and common genetic variants in up to ~192,000 individuals, and used ~155,063 samples for independent replication. We identified 31 novel blood pressure or hypertension associated genetic regions in the general population, including three rare missense variants in RBM47, COL21A1 and RRAS with larger effects (>1.5mmHg/allele) than common variants. Multiple rare, nonsense and missense variant associations were found in A2ML1 and a low-frequency nonsense variant in ENPEP was identified. Our data extend the spectrum of allelic variation underlying blood pressure traits and hypertension, provide new insights into the pathophysiology of hypertension and indicate new targets for clinical intervention