Health Start School-Based Clinic Staff and Hmong Adolescents: Does the Servant Leadership Theory Apply?

This pilot study investigated whether the staff at Health Start\u27s school-based clinics and the Hmong adolescents they serve are in agreement as to what health services Hmong adolescents want from the clinic and staff. In investigating this issue, servant leadership theory also was applied to answer the question: Does using servant leadership theory assist the staff in delivering culturally congruent healthcare to Hmong adolescents? According to Servant Leadership Theory, leaders first want to serve for the purpose of developing a healthier, wiser, freer, more autonomous follower. This theory, manifested by Robert K. Greenleaf through his work experiences and thinking about leadership issues, was applied to the staff and analyzed in order to understand how this theory will benefit them and their service delivery. This pilot study asked the following questions to answer how the services were perceived by Hmong adolescents and if the staff exhibited any traits of servant leadership: What kinds of comprehensive health services do the Hmong adolescents in the St. Paul schools want from the school-based clinic staff? What comprehensive health services does the staff think the Hmong adolescents want from the clinic and staff

Plasma from Volunteers Breathing Helium Reduces Hypoxia-Induced Cell Damage in Human Endothelial Cells-Mechanisms of Remote Protection Against Hypoxia by Helium.

PurposeRemote ischemic preconditioning protects peripheral organs against prolonged ischemia/reperfusion injury via circulating protective factors. Preconditioning with helium protected healthy volunteers against postischemic endothelial dysfunction. We investigated whether plasma from helium-treated volunteers can protect human umbilical vein endothelial cells (HUVECs) against hypoxia in vitro through release of circulating of factors.MethodsHealthy male volunteers inhaled heliox (79% helium, 21% oxygen) or air for 30 min. Plasma was collected at baseline, directly after inhalation, 6 h and 24 h after start of the experiment. HUVECs were incubated with either 5% or 10% of the plasma for 1 or 2 h and subjected to enzymatically induced hypoxia. Cell damage was measured by LDH content. Furthermore, caveolin 1 (Cav-1), hypoxia-inducible factor (HIF1α), extracellular signal-regulated kinase (ERK)1/2, signal transducer and activator of transcription (STAT3) and endothelial nitric oxide synthase (eNOS) were determined.ResultsPrehypoxic exposure to 10% plasma obtained 6 h after helium inhalation decreased hypoxia-induced cell damage in HUVEC. Cav-1 knockdown in HUVEC abolished this effect.ConclusionsPlasma of healthy volunteers breathing helium protects HUVEC against hypoxic cell damage, possibly involving circulating Cav-1

Multimodal Machine Learning-based Knee Osteoarthritis Progression Prediction from Plain Radiographs and Clinical Data

Knee osteoarthritis (OA) is the most common musculoskeletal disease without a cure, and current treatment options are limited to symptomatic relief. Prediction of OA progression is a very challenging and timely issue, and it could, if resolved, accelerate the disease modifying drug development and ultimately help to prevent millions of total joint replacement surgeries performed annually. Here, we present a multi-modal machine learning-based OA progression prediction model that utilizes raw radiographic data, clinical examination results and previous medical history of the patient. We validated this approach on an independent test set of 3,918 knee images from 2,129 subjects. Our method yielded area under the ROC curve (AUC) of 0.79 (0.78-0.81) and Average Precision (AP) of 0.68 (0.66-0.70). In contrast, a reference approach, based on logistic regression, yielded AUC of 0.75 (0.74-0.77) and AP of 0.62 (0.60-0.64). The proposed method could significantly improve the subject selection process for OA drug-development trials and help the development of personalized therapeutic plans

Pengaruh Perubahan Logo PT. Dua Kelinci Terhadap Persepsi Target Audience Di Surabaya

Logo merupakan lambang yang mewakili citra sebuah Perusahaan, memasuki era globalisasi saat ini cukup banyak Perusahaan yang melakukan Perubahan logo, salah satunya adalah PT. Dua Kelinci yang merupakan Perusahaan industri makanan dan minuman serta dikenal sebagai produsen kacang terkemuka di Indonesia. Tujuan penelitian ini adalah untuk mengetahui pengaruh Perubahan logo PT. Dua Kelinci terhadap persepsi target audience di Surabaya mengenai profesionalisme Perusahaan dan estetika logo Perusahaan. Hasil penelitian menunjukkan bahwa Perubahan logo telah tepat dilakukan oleh Perusahaan, dimana logo lama dimodifikasi menjadi logo baru, dapat diterima dan dipersepsikan secara positif oleh target audience. Logo baru memenuhi semua kriteria logo yang baik berdasarkan teori David E. Carter dan profesionalisme Perusahaan yang semakin meningkat tercermin dalam USAha Perusahaan mempertahankan konsistensi logo barunya pada berbagai media

Kepercayaan Sebagai Salah Satu Faktor Kepuasan Kerja Untuk Mencapai Keberhasilan Proyek Perumahan

Penelitian ini bertujuan untuk mengetahui variabel yang paling dominan dalam membetuk kepercayaan diantara competence trust, integrity trust dan intuitive trust dan untuk mengetahui pengaruh hubungan kepercayaan terhadap kesuksesan proyek dengan menggunakan kepuasan kerjasama sebagai mediator. Populasi dalam penelitian ini adalah Perusahaan kontraktor yang telah mengerjakan atau menyelesaikan proyek di wilayah Surabaya. Sampel dalam penelitian ini berjumlah 40 responden, yang terdiri dari 23 owner (pemilik proyek) dan 17 orang kontraktor (pelaksana proyek). Analisis data dilakukan dengan bantuan software IBM SPSS 20 dan Smart PLS. Dari ketiga variabel yang membentuk variabel Trust (X), dapat disimpulkan bahwa model yang paling dominan dalam membentuk kepercayaan dalam pelaksanaan proyek adalah Integrity Trust, dengan mean loading factor sebesar 0,8402. Hasil penelitian ini juga menunjukkan bahwa Trust memiliki pengaruh yang positif signifikan terhadap Kesuksesan Proyek dengan menggunakan Kepuasan Kerjasama sebagai mediator, dimana koefisiensi pengaruh tidak langsung dari Trust ke Kepuasan Kepuasan Kerjasama dan ke Kesuksesan Proyek, yaitu sebesar 0,5745 (57,45%), lebih besar dibandingkan dengan pengaruh langsung dari Trust ke Kesuksesan Proyek, yaitu sebesar 0,3390 (33,90%)

Redesain Kemasan Oleh-oleh Khas Kabupaten Sumbawa

Kabupaten Sumbawa terletak di pulau Sumbawa, provinsi Nusa Tenggara Barat. Kunjungan wisata keKabupaten Sumbawa mengalami peningkatan setiap tahunnya. Salah satu pendukung kegiatan pariwisata adalaholeh-oleh. Oleh-oleh dapat berupa jajanan tradisional. Salah satu produsen jajanan tradisional adalah Usaha Kecildan Menengah (UKM). Namun Karena keterbatasan informasi mengenai kemasan, para UKM mengalamimasalah tidak bisa masuk ke supermarket-supermarket besar serta kurang bisa mengenalkan produk jajananSumbawa sebagai oleh-oleh. Dengan redesain kemasan oleh-oleh jajanan khas Sumbawa, diharapkan wisatawanyang berkunjung ke Sumbawa bisa mengenal beragam produk jajanan Sumbawa dan menarik minat merekauntuk membelinya sebagai oleh-oleh

Increased maternal TSH and decreased maternal FT4 are associated with a higher operative delivery rate in low-risk pregnancies:A prospective cohort study

Background:  The increasing number of operative deliveries is a topic of major concern in modern obstetrics. Maternal thyroid function is of known influence on many obstetric parameters. Our objective was to investigate a possible relation between maternal thyroid function, and operative deliveries. Secondary aim was to explore whether thyroid function was related to specific reasons for operative deliveries. Methods:  In this prospective cohort study, low-risk Caucasian women, pregnant of a single cephalic fetus were included. Women with known auto-immune disease, a pre-labour Caesarean section, induction of labour, breech presentation or preterm delivery were excluded. In all trimesters of pregnancy the thyroid function was assessed. Differences in mean TSH and FT4 were assessed using t-test. Mean TSH and FT4 levels for operative deliveries were determined by one way ANOVA. Repeated measurement analyses were performed (ANOVA), adjusting for BMI, partiy, maternal age and gestational age at delivery. Results:  In total 872 women were included, of which 699 (80.2 %) had a spontaneous delivery. At 36 weeks gestation women who had an operative delivery had a significantly higher mean TSH (1.63mIU/L versus 1.46mIU/L, p = 0.025) and lower mean FT4 (12.9pmol/L versus 13.3pmol/L, p = 0.007)) compared to women who had a spontaneous delivery. Mean TSH was significantly higher (p = 0.026) and mean FT4 significantly lower (p = 0.030) throughout pregnancy for women with an operative delivery due to failure to progress in second stage of labour, compared to women with a spontaneous delivery or operative delivery for other reasons. Conclusion:  Increased TSH and decreased FT4 seem to be associated with more operative vaginal deliveries and Caesarean sections. After adjusting for several confounders the association remained for operative deliveries due to failure to progress in second stage of labour, possibly to be explained by less efficient uterine action