Strongly star-forming rotating disks in a complex merging system at z = 4,7 as revealed by ALMA

We performed a kinematical analysis of the [CII] line emission of the BR 1202-0725 system at z~4,7 using ALMA observations. The most prominent sources of this system are a quasar and a submillimeter galaxy, separated by a projected distance of about 24 kpc and characterized by very high SFR, higher than 1000 Msun/yr. However, the ALMA observations reveal that these galaxies apparently have undisturbed rotating disks, which is at variance with the commonly accepted scenario in which strong star formation activity is induced by a major merger. We also detected faint components which, after spectral deblending, were spatially resolved from the main QSO and SMG emissions. The relative velocities and positions of these components are compatible with orbital motions within the gravitational potentials generated by the QSO host galaxy and the SMG, suggesting that they are smaller galaxies in interaction or gas clouds in accretion flows of tidal streams. We did not find any clear spectral evidence for outflows caused by AGN or stellar feedback. This suggests that the high star formation rates might be induced by interactions or minor mergers with these companions, which do not affect the large-scale kinematics of the disks, however. Our kinematical analysis also indicates that the QSO and the SMG have similar Mdyn, mostly in the form of molecular gas, and that the QSO host galaxy and the SMG are seen close to face-on with slightly different disk inclinations: the QSO host galaxy is seen almost face-on (i~15), while the SMG is seen at higher inclinations (i~25). Finally, the ratio between the black hole mass of the QSO, obtained from XShooter spectroscopy, and the Mdyn of the host galaxy is similar to value found in very massive local galaxies, suggesting that the evolution of black hole galaxy relations is probably better studied with dynamical than with stellar host galaxy masses.Comment: Accepted for publication in Astronomy and Astrophysic

The assembly of massive galaxies from NIR observations of the Hubble Deep Field South

We use a deep K(AB)<25 galaxy sample in the Hubble Deep Field South to trace the evolution of the cosmological stellar mass density from z~ 0.5 to z~3. We find clear evidence for a decrease of the average stellar mass density at high redshift, 2<z<3.2, that is 15^{+25}_{-5}% of the local value, two times higher than what observed in the Hubble Deep Field North. To take into account for the selection effects, we define a homogeneous subsample of galaxies with 10^{10}M_\odot \leq M_* \leq 10^{11}M_\odot: in this sample, the mass density at z>2 is 20^{+20}_{-5} % of the local value. In the mass--limited subsample at z>2, the fraction of passively fading galaxies is at most 25%, although they can contribute up to about 40% of the stellar mass density. On the other hand, star--forming galaxies at z>2 form stars with an average specific rate at least ~4 x10^{-10} yr$^{-1}$, 3 times higher than the z<~1 value. This implies that UV bright star--forming galaxies are substancial contributors to the rise of the stellar mass density with cosmic time. Although these results are globally consistent with $\Lambda$--CDM scenarios, the present rendition of semi analytic models fails to match the stellar mass density produced by more massive galaxies present at z>2.Comment: Accepted for publication on ApJLetter

The survival advantage of pancreas after kidney transplant

Patient survival after pancreas after kidney transplant (PAK) has been reported to be inferior to patient survival after simultaneous pancreas–kidney transplant (SPK). The authors examine national data to further explore allograft (kidney and pancreas) and patient survival after PAK. Kaplan–Meier and Cox proportional hazard models were used to analyze Organ Procurement and Transplantation Network data from 1995 to 2010. The analysis compared PAK and SPK candidates and recipients. Kaplan–Meier analysis results showed that PAK after either a living or a deceased donor kidney transplant is associated with increased kidney graft survival compared with recipients with type 1 diabetes who received only a kidney. The best kidney allograft survival was for patients who received a living donor kidney followed by PAK. Receiving a living donor kidney was associated with increased pancreas allograft survival compared with receiving a deceased donor kidney. PAK transplant recipients who receive both organs have a survival advantage compared with uremic candidates who receive neither (SPK waitlist). Compared with uremic diabetic waitlist patients, SPK and PAK recipients showed similar overall patient survival. Successful PAK offers a survival advantage compared with receiving neither a kidney nor a pancreas transplant. These data also suggest that receiving a pancreas (after kidney) transplant may have a protective effect on the kidney allograft

The evolution of the galaxy luminosity function in the rest frame blue band up to z=3.5

We present an estimate of the cosmological evolution of the field galaxy luminosity function (LF) in the rest frame 4400 Angstrom B -band up to redshift z=3.5. To this purpose, we use a composite sample of 1541 I--selected galaxies selected down to I_(AB)=27.2 and 138 galaxies selected down to K_(AB)=25 from ground-based and HST multicolor surveys, most notably the new deep JHK images in the Hubble Deep Field South (HDF-S) taken with the ISAAC instrument at the ESO-VLT telescope. About 21% of the sample has spectroscopic redshifts, and the remaining fraction well calibrated photometric redshifts. The resulting blue LF shows little density evolution at the faint end with respect to the local values, while at the bright end (M_B(AB)<-20) a brightening increasing with redshift is apparent with respect to the local LF. Hierarchical CDM models overpredict the number of faint galaxies by about a factor 3 at z=1. At the bright end the predicted LFs are in reasonable agreement only at low and intermediate redshifts (z=1), but fail to reproduce the pronounced brightening observed in the high redshift (z=2-3) LF. This brightening could mark the epoch where a major star formation activity is present in the galaxy evolution.Comment: 14 pages, 2 figures, Astrophysical Journal Letters, in pres

Broadened Allocation of Pancreas Transplants Across Compatible ABO Blood Types

Background Current Organ Procurement and Transplantation Network (OPTN) policy restricts certain blood type-compatible simultaneous pancreas and kidney (SPK) transplants. Using the Kidney Pancreas Simulated Allocation Model, we examined the effects of 5 alternative allocation sequences that allowed all clinically compatible ABO transplants. Methods The study cohort included kidney (KI), SPK, and pancreas alone (PA) candidates waiting for transplant for at least 1 day between January 1, 2010, and December 31, 2010 (full cohort), and kidneys and pancreata recovered for transplant during the same period. Additionally, because the waiting list has shrunk since 2010, the study population was reduced by random sampling to match the volume of the 2015 waiting list (reduced cohort). Results Compared with the current allocation sequence, R4 and R5 both showed an increase in SPK transplants, a nearly corresponding decrease in KI transplants, and virtually no change in PA transplants. Life-years from transplant and median years of benefit also increased. The distribution of transplants by blood type changed, with more ABO:A, B, and AB transplants performed, and fewer ABO:O across all transplant types (KI, SPK, PA), with the relative percent changes largest for SPK. Discussion Broadened ABO compatibility allowances primarily benefitted SPK ABO:A and AB candidates. ABO:O candidates saw potentially reduced access to transplant. The simulation results suggest that modifying the current allocation sequence to incorporate broadened ABO compatibility can result in an increase in annual SPK transplants

Fluctuations and Entropy Indices of QCD Parton Showers

The branching processes in parton showers are studied in perturbative QCD for both quark and gluon jets. The emphasis is on the nature of fluctuations of both the parton multiplicities and the spatial patterns of the final states. Effective measures of such fluctuations are calculated from the data obtained by Monte Carlo simulations. The entropy indices are used to characterize chaoticity. Both running and fixed couplings are considered. The fixed coupling case is used to study the onset of chaos. Implications of the results are discussed.Comment: 8 pages, LaTex, 12 figures in a single postscript file, submitted to Phys. Rev. D. Hard copy sent upon request to [email protected]

Isoscalar resonances with J^{PC}=1^{--} in e^+e^-annihilation

The analysis of the vector isoscalar excitations in the energy range between 1 and 2 GeV of the $e^+e^-$ annihilation is presented for the final states $\pi^+\pi^-\pi^0$, $\omega\pi^+\pi^-$, $K^+K^-$, $K^0_SK^\pm\pi^\mp$ and $K^{\ast0}K^-\pi^++ c.c$. The effects of both the resonance mixing and the successive opening of multiparticle channels, with the energy dependent partial widths, are taken into account. The work extends our previous analysis hep-ph/9609216 of the vector isovector excitations and is aimed to compare the existing data with the predictions of the $q\bar q$ model. It is shown that this hypothesis does not contradict the data.Comment: 16 pages, revtex, 6 ps figures. Clarifying remarks, a table, and references are added. Accepted in Phys. Rev.

A study of the nuclear medium influence on transverse momentum of hadrons produced in deep inelastic neutrino scattering

The influence of nuclear effects on the transverse momentum $(p_T)$ distributions of neutrinoproduced hadrons is investigated using the data obtained with SKAT propane-freon bubble chamber irradiated in the neutrino beam (with $E_{\nu}$ = 3-30 GeV) at Serpukhov accelerator. Dependences of $$on the kinematical variables of inclusive deep-inelastic scattering and of the produced hadrons are measured. It has been observed, that the nuclear effects cause an enhancement of$$ of hadrons (more pronounced for the positively charged ones) produced in the target fragmentation region at low invariant mass of the hadronic system (2 $< W <$ 4 GeV) or at low energies transferred to the current quark (2 $< \nu < 9$ GeV). At higher $W$ or $\nu$, no influence of nuclear effects on $$ is observed. Measurement results are compared with predictions of a simple model, incorporating secondary intranuclear interactions of hadrons (with a formation length extracted from the Lund fragmentation model), which qualitatively reproduces the main features of the data.Comment: 23 pages, 7 figure

BR1202-0725: An Extreme Multiple Merger at z = 4.7

The radio-quiet quasar BR1202-0725 (z=4.695) is a remarkable source with a bright Northwest (NW) companion detected at submm and radio wavelengths but invisible in the optical. In the absence of amplification by gravitational lensing, BR1202-0725 would be the most luminous binary CO and FIR source in the Universe. In this paper, we report observations with the IRAM Plateau de Bure interferometer of BR1202-0725 in the redshifted emission of the CO(5-4) and (7-6) lines, the [C I](3P2-3P1) line, a high angular resolution (0.3 x 0.8 arcsec) 1.3 mm map of the rest-frame, far-IR dust continuum, and a search for the CO(11-10) line. We compare these results with recent ALMA data in the [C II] line. Both the quasar host galaxy and its NW companion are spatially resolved in the molecular line emission and the dust continuum. The CO profile of the NW companion is very broad with a full width at half maximum of 1000 +/- 130 km/s, compared to 360 +/- 40 km/s for the quasar host galaxy to the Southeast (SE). The difference in linewidths and center velocities, and the absence of any lens candidate or arc-like structure in the field, at any wavelength, show that the obscured NW galaxy and the SE quasar host galaxy cannot be lensed images of the same object. Instead, we find morphological and kinematic evidence for sub-structures in both the NW and SE sources. We interpret these results as strong indications that the BR1202-0725 complex is a group of young, interacting, and highly active starburst galaxies.Comment: Minor changes to agree with published versio

Computational Reconstruction of Multidomain Proteins Using Atomic Force Microscopy Data

SummaryClassical structural biology techniques face a great challenge to determine the structure at the atomic level of large and flexible macromolecules. We present a novel methodology that combines high-resolution AFM topographic images with atomic coordinates of proteins to assemble very large macromolecules or particles. Our method uses a two-step protocol: atomic coordinates of individual domains are docked beneath the molecular surface of the large macromolecule, and then each domain is assembled using a combinatorial search. The protocol was validated on three test cases: a simulated system of antibody structures; and two experimentally based test cases: Tobacco mosaic virus, a rod-shaped virus; and Aquaporin Z, a bacterial membrane protein. We have shown that AFM-intermediate resolution topography and partial surface data are useful constraints for building macromolecular assemblies. The protocol is applicable to multicomponent structures connected in the polypeptide chain or as disjoint molecules. The approach effectively increases the resolution of AFM beyond topographical information down to atomic-detail structures