X-ray emission from high-redshift miniquasars: self-regulating the population of massive black holes through global warming

Observations of high-redshift quasars at z>6 imply that supermassive black holes (SMBHs) with masses over a billion solar masses were in place less than 1 Gyr after the Big Bang. If these SMBHs assembled from "seed" BHs left behind by the first stars, then they must have accreted gas at close to the Eddington limit during a large fraction (>50%) of the time. A generic problem with this scenario, however, is that the mass density in million-solar-mass SMBHs at z=6 already exceeds the locally observed SMBH mass density by several orders of magnitude; in order to avoid this overproduction, BH seed formation and growth must become significantly less efficient in less massive protogalaxies, while proceeding uninterrupted in the most massive galaxies that formed first. Using Monte-Carlo realizations of the merger and growth history of BHs, we show that X-rays from the earliest accreting BHs can provide such a feedback mechanism. Our calculations paint a self-consistent picture of black-hole-made climate change, in which the first miniquasars---among them the ancestors of the z>6 quasar SMBHs---globally warm the IGM and suppress the formation and growth of subsequent generations of BHs. We present two specific models with global miniquasar feedback that provide excellent agreement with recent estimates of the z=6 SMBH mass function. For each of these models, we estimate the rate of BH mergers at z>6 that could be detected by the proposed gravitational-wave observatory eLISA/NGO.Comment: 15 pages, 6 figures, accepted to MNRAS; v2 includes minor changes, mostly to references, to match version to be publishe

Chern-Simons black holes: scalar perturbations, mass and area spectrum and greybody factors

We study the Chern-Simons black holes in d-dimensions and we calculate analytically the quasi-normal modes of the scalar perturbations and we show that they depend on the highest power of curvature present in the Chern-Simons theory. We obtain the mass and area spectrum of these black holes and we show that they have a strong dependence on the topology of the transverse space and they are not evenly spaced. We also calculate analytically the reflection and transmission coefficients and the absorption cross section and we show that at low frequency limit there is a range of modes which contributes to the absorption cross section.Comment: 19 pages, 18 figures, the title has been changed to reflect the addition of an another section on the reflection, transmission coefficients and absorption cross sections of the Chern-Simons black holes. Version to be published in JHE

Measuring Daily Events and Experiences: Decisions for the Researcher

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/98999/1/j.1467-6494.1991.tb00260.x.pd

Experimental determination of the magnetic interactions of frustrated Cairo pentagon lattice materials

We present inelastic neutron scattering measurements of the Cairo pentagon lattice magnets Bi$_2$Fe$_4$O$_9$ and Bi$_4$Fe$_5$O$_{13}$F, supported by high field magnetisation measurements of Bi$_2$Fe$_4$O$_9$. Using linear spin wave theory and mean field analyses we determine the spin exchange interactions and single-ion anisotropy in these materials. The Cairo lattice is geometrically frustrated and consists of two inequivalent magnetic sites, both occupied by Fe$^{3+}$ ions and connected by two competing nearest neighbour interactions. We found that one of these interactions, coupling nearest neighbour spins on the three-fold symmetric sites, is extremely strong and antiferromagnetic. These strongly coupled dimers are then weakly coupled to a framework formed from spins occupying the other inequivalent site. In addition we found that the Fe$^{3+}$ $S=5/2$ spins have a non-negligible single-ion anisotropy, which manifests as a spin anisotropy gap in the neutron spectrum and a spin-flop transition in high field magnetisation measurements.Comment: 10 pages, 9 figure

VnD: a structure-centric database of disease-related SNPs and drugs

Numerous genetic variations have been found to be related to human diseases. Significant portion of those affect the drug response as well by changing the protein structure and function. Therefore, it is crucial to understand the trilateral relationship among genomic variations, diseases and drugs. We present the variations and drugs (VnD), a consolidated database containing information on diseases, related genes and genetic variations, protein structures and drug information. VnD was built in three steps. First, we integrated various resources systematically to deduce catalogs of disease-related genes, single nucleotide polymorphisms (SNPs), protein mutations and relevant drugs. VnD contains 137 195 disease-related gene records (13 940 distinct genes) and 16 586 genetic variation records (1790 distinct variations). Next, we carried out structure modeling and docking simulation for wild-type and mutant proteins to examine the structural and functional consequences of non-synonymous SNPs in the drug-related genes. Conformational changes in 590 wild-type and 4437 mutant proteins from drug-related genes were included in our database. Finally, we investigated the structural and biochemical properties relevant to drug binding such as the distribution of SNPs in proximal protein pockets, thermo-chemical stability, interactions with drugs and physico-chemical properties. The VnD database, available at http://vnd.kobic.re.kr:8080/VnD/ or vandd.org, would be a useful platform for researchers studying the underlying mechanism for association among genetic variations, diseases and drugs