Management of patients with back pain in outpatient practice

The authors studied the efficiency of drug therapy using the nonsteroidal anti-inflammatory drug (NSAID) meloxicam (Movalis) for nonspecific back pain and radiculopathy in the outpatient practice (without physio-, reflex, and manual therapies). Examination of 156 patients revealed a specific cause of back pain only in 6 (3.8%). Drug therapy using Movalis in 150 patients with acute, subacute, chronic nonspecific back pain at various sites or radiculopathy resulted in a considerable reduction in pain (as high as 1-3 VAS scores) and its complete regression in 97.3% of cases within 2-3 weeks of treatment. Movalis therapy was found to be well tolerated and caused a low frequency of side effects (1.7%) as mild gastrointenstinal disorders; Movalis used in combination with antiepileptic agents (pregabalin and gabapentin), myorelaxants (Midocalm) and Milgamma in some patents was ascertained to be also well tolerated

Mineral Concentrates As a Factor of the Khibiny Apatite-Nepheline Ores Efficiency Improvement

Apatite-nepheline ores of the Khibiny deposits contain the largest phosphorus-bearing resources in the world, and, at the same time, they contain associated valuable components in the rock-forming minerals — apatite, nepheline, sphene and titanium magnetite. Intensive development of the Khibiny deposits with production of only apatite concentrate and a small part of nepheline concentrate resulted in the accumulation of over 1.0 billion tons of wastes in tailing storage facilities and dumps during 90 years of JSC Apatit operation. The possibility of increasing the efficiency of the use of the main concentrates of apatite-nepheline ores of the Khibiny deposits and wastes for their processing is considered through the use of technological developments of the FRC KSC RAS, JSC RIFI and JSC Apatit to obtain traditional and new target products. A fundamentally new approach to the problem of sustainable use of natural resources is focused on establishment of the whole production chain in the region, from mining and processing operations to manufacturers of final high technology products (rare-earth products, welding and construction materials, coloring agents and other materials). They also determine the level of industrial technical progress. Keywords: Khibiny apatite-nepheline ores, mineral raw materials, extraction and processing, new material

Channel matrix form impact on parameters of deformation of screw broadening pressing

Виконано аналіз впливу форми каналу матриці на параметри процесу деформування заготовок. Показано, що при проходженні заготовкою робочого каналу матриці накопичена деформація визначаеться сумарною по зонам деформування. Розподіл максимального рівня накопиченої інтенсивності деформацій по перерізу заготовки, залежить від геометричних параметрів матриці і практично не залежить від механічних властивостей та виду матеріалу заготовки. Дана оцінка ступеню реалізації характеристики матриці з урахуванням взаємодії механізмів гвинтового деформування та проковзування матеріалу при гвинтовому уширячому пресуванні в напрямку осі руху заготовки.The analysis of influence of form of channel of matrix is executed on the parameters of process of deformation. It is shown that at passing the accumulated deformation is determined the purveyance of working channel of matrix by total on zones deformation. Distribution of maximal level of the accumulated intensity of deformations on the section of purveyance, depends on the geometrical parameters of matrix and practically does not depend on mechanical properties and type of material of purveyance. This estimation of degree of realization of description of matrix taking into account cooperation of mechanisms screw of deformation and slipping of material at the screw broadening pressing in the direction of axis of motion of purveyance. It is set that the presence of mechanism of slipping for an elliptic matrix can decrease size of the accumulated deformation in a peripheral zone. Thus experimental distribution of deformations gives the error of determination no more 11% with a curve that takes into account two mechanisms of deformation.Выполнен анализ влияния формы канала матрицы на параметры процесса деформирования. Показано, что при прохождении заготовкой рабочего канала матрицы накопленная деформация определяется суммарной по зонам деформацией. Распределение максимального уровня накопленной интенсивности деформаций по сечению заготовки, зависит от геометрических параметров матрицы и практически не зависит от механических свойств и вида материала заготовки. Данна оценка степени реализации характеристики матрицы с учетом взаимодействия механизмов винтового деформирования и проскальзывания материала при винтовом уширяющем прессовании в направлении оси движения заготовки

Psychology of Mobbing as a Form of Conflict in the Workplace: Finding and Testing Project-Based Learning in Students’ Education

Project-based learning has long been used in universities when preparing students. However, project-based technologies are currently being increasingly used in work with students. The authors found various options for the application of these technologies in teaching psychological and pedagogical disciplines. The research aims to determine the practice of implementing project-based learning to provide a deeper practice-oriented understanding of academic disciplines. The authors use a set of methods of theoretical analysis and practical psychological techniques. The authors present the research results in the form of several generalizations. The first one concerns the fact that mobbing has recently become a stable trend in teams; a conflict often manifests itself in the form of mobbing. The study of various organizational cultures and their models shows that the optimal and morally oriented model of organizational culture is the barrier preventing the development of mobbing in the company. The practical application of the developed theory provides methodological support for training a successful specialist

Engagement in Online Learning Through the Lens of Adults' Learning Experience

The article aims to critically examine the role of engagement in the study of the educational experiences of adult learners in online learning. The authors highlight the existence of a gap between the nature of adult educational experiences and the lens through which these experiences are studied and evaluated. This lens is the learners' engagement. The authors highlight the complexity of the construct of learner engagement and point out the inadequacy of assessing it solely through behavioral markers. The theoretical framework of the article is the Community of Inquiry (CoI) model for studying the educational experiences of learners in the digital environment, based on the notion of the socially constructed nature of learning. The article shows how the idea of lifelong learning as the formation of a new professional identity of adults is consistent with the idea of an ontological turn in education. By conceptualizing the educational experiences of adults as active participants in the learning process, the authors propose to consider engagement as a characteristic of these experiences. The authors identify external and internal factors of learner engagement. Based on previous research, internal factors are proposed, namely learners’ prior experience, future self-image, and personal goals. External factors are based on the self-determination theory, where the needs for competence and belongingness become particularly salient for engagement in online learning

A tetrachotomy of ontology-mediated queries with a covering axiom

Our concern is the problem of efficiently determining the data complexity of answering queries mediated by descrip- tion logic ontologies and constructing their optimal rewritings to standard database queries. Originated in ontology- based data access and datalog optimisation, this problem is known to be computationally very complex in general, with no explicit syntactic characterisations available. In this article, aiming to understand the fundamental roots of this difficulty, we strip the problem to the bare bones and focus on Boolean conjunctive queries mediated by a simple cov- ering axiom stating that one class is covered by the union of two other classes. We show that, on the one hand, these rudimentary ontology-mediated queries, called disjunctive sirups (or d-sirups), capture many features and difficulties of the general case. For example, answering d-sirups is Π2p-complete for combined complexity and can be in AC0 or L-, NL-, P-, or coNP-complete for data complexity (with the problem of recognising FO-rewritability of d-sirups be- ing 2ExpTime-hard); some d-sirups only have exponential-size resolution proofs, some only double-exponential-size positive existential FO-rewritings and single-exponential-size nonrecursive datalog rewritings. On the other hand, we prove a few partial sufficient and necessary conditions of FO- and (symmetric/linear-) datalog rewritability of d- sirups. Our main technical result is a complete and transparent syntactic AC0 / NL / P / coNP tetrachotomy of d-sirups with disjoint covering classes and a path-shaped Boolean conjunctive query. To obtain this tetrachotomy, we develop new techniques for establishing P- and coNP-hardness of answering non-Horn ontology-mediated queries as well as showing that they can be answered in NL

Осознание ценности жизни в пересечении этических позиций (анализ результатов социологического исследования динамики отношения к проблемам биоэтики российских студентов-медиков)

It is analyzed attitude to such problems as abortion, euthanasia, cloning of human being, artificial fertilization, fetal therapy depending on outlook and values of students. In particular, students’ attitude to the course teaching is examined as well as their per- sonal interest in the course. Conclusions are based on applied sociological research data.В статье анализируется осознание проблем абортов, эвтаназии, клонирования человека, искусственного оплодотворе- ния, фетальной терапии в зависимости от мировоззренческих и ценностных приоритетов. Рассматривается динамика пони- мания биоэтических проблем от «уровня мнения» до «уровня логоса» как результат преподавания курса биоэтики. Выводы статьи основаны на данных прикладных социологических исследований

A tetrachotomy of ontology-mediated queries with a covering axiom

Our concern is the problem of efficiently determining the data complexity of answering queries mediated by descrip- tion logic ontologies and constructing their optimal rewritings to standard database queries. Originated in ontology- based data access and datalog optimisation, this problem is known to be computationally very complex in general, with no explicit syntactic characterisations available. In this article, aiming to understand the fundamental roots of this difficulty, we strip the problem to the bare bones and focus on Boolean conjunctive queries mediated by a simple cov- ering axiom stating that one class is covered by the union of two other classes. We show that, on the one hand, these rudimentary ontology-mediated queries, called disjunctive sirups (or d-sirups), capture many features and difficulties of the general case. For example, answering d-sirups is Π2p-complete for combined complexity and can be in AC0 or L-, NL-, P-, or coNP-complete for data complexity (with the problem of recognising FO-rewritability of d-sirups be- ing 2ExpTime-hard); some d-sirups only have exponential-size resolution proofs, some only double-exponential-size positive existential FO-rewritings and single-exponential-size nonrecursive datalog rewritings. On the other hand, we prove a few partial sufficient and necessary conditions of FO- and (symmetric/linear-) datalog rewritability of d- sirups. Our main technical result is a complete and transparent syntactic AC0 / NL / P / coNP tetrachotomy of d-sirups with disjoint covering classes and a path-shaped Boolean conjunctive query. To obtain this tetrachotomy, we develop new techniques for establishing P- and coNP-hardness of answering non-Horn ontology-mediated queries as well as showing that they can be answered in NL

Hanbury Brown and Twiss interferometry at a free-electron laser

We present measurements of second- and higher-order intensity correlation functions (so-called Hanbury Brown and Twiss experiment) performed at the free-electron laser (FEL) FLASH in the non-linear regime of its operation. We demonstrate the high transverse coherence properties of the FEL beam with a degree of transverse coherence of about 80% and degeneracy parameter of the order 10^9 that makes it similar to laser sources. Intensity correlation measurements in spatial and frequency domain gave an estimate of the FEL average pulse duration of 50 fs. Our measurements of the higher-order correlation functions indicate that FEL radiation obeys Gaussian statistics, which is characteristic to chaotic sources.Comment: 19 pages, 6 figures, 1 table, 40 reference

Efficiency of local therapy with the use of a new preparation for oral care at periodontitis in the course of hyperpeptic gastritis after tobacco smoke intoxication

Periodontal diseases, arising against a background of stomach pathology at tobacco addiction remain an acute problem of modern dentistry. The aim of the work is an experimental study of efficiency of application of the new preparation for oral care during treatment of periodontitis simulated against a background of hyperpeptic gastritis under conditions of intoxication by tobacco smoke. At the first stage all experimental animals were divided into 4 groups: І - intact, II - with simulated periodontitis, III - with simulated periodontitis against a background of simulated hyperpeptic gastritis, IV - with simulated periodontitis against a background of hyperpeptic gastritis under conditions of tobacco smoking. Biochemical researches at periodontitis in rats were conducted for determination of influencing stomach pathology and tobacco smoke. On the II stage efficiency of local therapy was studied with the use of the new preparation for oral care and a comparator agent.Results: At experimental periodontitis against a background of hyperpeptic gastritis under conditions of smoking the considerable changes in periodontal tissues typical for the inflammatory process develop. The local therapy at rats with the use of the new preparation resulted in accelerating removing harmful influence of damaging factors and restoring the state of periodontal tissues, than in case of application of the comparator agent. The efficiency of the new preparation consists in normalizing influence on processes of lipid peroxidation, inflammation and activation of the protective systems of oral cavity during periodontitis which arises up against a background of hyperpeptic gastritis