160 research outputs found

    Content-based Recommender Systems for Heritage: Developing a Personalised Museum Tour

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    Towards evaluating the impact of recommender systems on visitor experience in physical museums

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    Recommender systems have been used in physical museums to improve visitor experience; yet to assess their impact empirically, researchers often rely on the user experience criteria alone. In this paper, we examine the multidimensionality of visitor experience, specifically the components and factors that shape it. We present a framework that is built on existing bodies of knowledge about visitor experience and that serves as a starting point to further evaluate the transformations caused by the integration of recommender systems in museums. We then conclude that current approaches to testing the impact of recommender systems on visitor experience should be expanded beyond evaluations of user satisfaction level to include the demonstrated aspects of visitor experience. This research aims to contribute to a more in-depth understanding of the differences between visitor and user experience types as well as to address the need for a more comprehensive set of guidelines to evaluate how recommender systems enhance visitor experience in physical museums

    Thermography of flame during diesel fuel combustion with steam gasification

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    The paper represents a study concerning the combustion of liquid hydrocarbon fuel in a perspective burner device with the controlled forced supply of overheated steam into the combustion zone, using diesel fuel. The thermal imaging measurements are conducted for the outer flame of the burner device in the wide range of regime parameters (flow rate and temperature of steam). A thermal imaging camera (FLIR, JADE J530SB) is used in the experiments. The effective emissivity coefficient of flame is obtained versus the flow rate of steam supplied. The steam parameters are found to influence on the temperature in the outer flame of the burner device

    Π’ΠΏΠ»ΠΈΠ² Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠ±Ρ–Π½ΠΎΠ²Π°Π½ΠΎΠ³ΠΎ ΠΊΡ€Π΅ΠΌΡƒ Π½Π° Π±Ρ–Π»ΠΊΠΎΠ²ΠΎ-синтСтичну Π°ΠΊΡ‚ΠΈΠ²Π½Ρ–ΡΡ‚ΡŒ ΠΊΠ»Ρ–Ρ‚ΠΈΠ½ Π½Π° ΠΌΠΎΠ΄Π΅Π»Ρ– Ρ‚Π΅Ρ€ΠΌΡ–Ρ‡Π½ΠΈΡ… пошкодТСнь ΡˆΠΊΡ–Ρ€ΠΈ Ρƒ Ρ‰ΡƒΡ€Ρ–Π²

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    Aim. To study the mechanisms of the reparative action of a new combined cream on the model of thermal burn injury in rats.Materials and methods. On the model of thermal burn in rats the reparative properties of the new combined cream under the conditional name β€œDermalipoin” containing Ξ±-lipoic acid, urea, olive oil, tea tree oil, PEG-400 were studied. To determine the level of the protein synthetic activity of cells (epitheliocytes of the stratified squamous epithelium in the epidermis and cells of the fibroblast cell in the edges of healing of thermal damage) the content of ribonucleoproteins (RNP) in the cytoplasm and deoxyribonucleoproteins (DNP) in the nuclei of the cells was assessed by the cytometric method.Results and discussion. On the model of thermal burn in rats β€œDermalipoin” cream showed a more active effect on reparative processes compared to the reference drugs – methyluracil ointment and β€œTitriol” gel. It indicates a significant increase in the protein synthetic function of epitheliocytes of the stratified squamous epithelium in the epidermis and cells of the fibroblastic series at the healing edges. The reparative activity of the cream was, first of all, provided by the presence of thiol (sulfhydryl) groups in the molecule of lipoic acid, giving it the properties of an antioxidant. The antioxidant effect of lipoic acid promotes more efficient DNA molecule reparation after damage as a result of the oxidative stress.Conclusions. β€œDermalipoin” cream shows a marked reparative effect due to the increase of the protein synthetic activity and acceleration of reparation of DNA molecules of epithelial cells after damage; as a result, the process of healing burns accelerates.ЦСль – исслСдованиС ΠΌΠ΅Ρ…Π°Π½ΠΈΠ·ΠΌΠΎΠ² Ρ€Π΅ΠΏΠ°Ρ€Π°Ρ‚ΠΈΠ²Π½ΠΎΠ³ΠΎ дСйствия Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΠΊΡ€Π΅ΠΌΠ° Π½Π° ΠΌΠΎΠ΄Π΅Π»ΠΈ тСрмичСской ΠΎΠΆΠΎΠ³ΠΎΠ²ΠΎΠΉ Ρ‚Ρ€Π°Π²ΠΌΡ‹ Ρƒ крыс.ΠœΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»Ρ‹ ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹. На ΠΌΠΎΠ΄Π΅Π»ΠΈ тСрмичСского ΠΎΠΆΠΎΠ³Π° Ρƒ крыс ΠΈΠ·ΡƒΡ‡Π΅Π½Ρ‹ Ρ€Π΅ΠΏΠ°Ρ€Π°Ρ‚ΠΈΠ²Π½Ρ‹Π΅ свойства Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΠΊΡ€Π΅ΠΌΠ°, условно Π½Π°Π·Π²Π°Π½Π½ΠΎΠ³ΠΎ Β«Π”Π΅Ρ€ΠΌΠ°Π»ΠΈΠΏΠΎΠΈΠ½Β», Π² состав ΠΊΠΎΡ‚ΠΎΡ€ΠΎΠ³ΠΎ вошли: Ξ±-липоСвая кислота, ΠΌΠΎΡ‡Π΅Π²ΠΈΠ½Π°, ΠΎΠ»ΠΈΠ²ΠΊΠΎΠ²Π΅ масло, масло Ρ‡Π°ΠΉΠ½ΠΎΠ³ΠΎ Π΄Π΅Ρ€Π΅Π²Π°, ΠŸΠ­Π“-400. Для опрСдСлСния уровня Π±Π΅Π»ΠΊΠΎΠ²ΠΎ-синтСтичСской активности ΠΊΠ»Π΅Ρ‚ΠΎΠΊ (эпитСлиоцитов многослойного плоского эпитСлия Π² Π·ΠΎΠ½Π΅ эпидСрмизации ΠΈ ΠΊΠ»Π΅Ρ‚ΠΎΠΊ фибробластичСского ряда Π² краях заТивлСния тСрмичСского поврСТдСния) ΠΏΡ€ΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΈ ΠΎΡ†Π΅Π½ΠΊΡƒ содСрТания Ρ€ΠΈΠ±ΠΎΠ½ΡƒΠΊΠ»Π΅ΠΎΠΏΡ€ΠΎΡ‚Π΅ΠΈΠ΄ΠΎΠ² Π² Ρ†ΠΈΡ‚ΠΎΠΏΠ»Π°Π·ΠΌΠ΅ ΠΈ дСзоксирибонуклСопротСидов Π² ядрах ΠΊΠ»Π΅Ρ‚ΠΎΠΊ ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ Ρ†ΠΈΡ‚ΠΎΡ„ΠΎΡ‚ΠΎΠΌΠ΅Ρ‚Ρ€ΠΈΠΈ.Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ ΠΈ ΠΈΡ… обсуТдСниС. На ΠΌΠΎΠ΄Π΅Π»ΠΈ тСрмичСского ΠΎΠΆΠΎΠ³Π° Ρƒ крыс ΠΊΡ€Π΅ΠΌ Π”Π΅Ρ€ΠΌΠ°Π»ΠΈΠΏΠΎΠΈΠ½ ΠΏΠΎ ΡΡ€Π°Π²Π½Π΅Π½ΠΈΡŽ с ΠΏΡ€Π΅ΠΏΠ°Ρ€Π°Ρ‚Π°ΠΌΠΈ сравнСния мазью ΠΌΠ΅Ρ‚ΠΈΠ»ΡƒΡ€Π°Ρ†ΠΈΠ»ΠΎΠ²ΠΎΠΉ ΠΈ Π³Π΅Π»Π΅ΠΌ Π’ΠΈΡ‚Ρ€ΠΈΠΎΠ» проявил Π±ΠΎΠ»Π΅Π΅ Π°ΠΊΡ‚ΠΈΠ²Π½ΠΎΠ΅ воздСйствиС Π½Π° Ρ€Π΅ΠΏΠ°Ρ€Π°Ρ‚ΠΈΠ²Π½Ρ‹Π΅ процСссы, ΠΎ Ρ‡Π΅ΠΌ ΡΠ²ΠΈΠ΄Π΅Ρ‚Π΅Π»ΡŒΡΡ‚Π²ΠΎΠ²Π°Π»ΠΎ достовСрноС ΡƒΠ²Π΅Π»ΠΈΡ‡Π΅Π½ΠΈΠ΅ Π±Π΅Π»ΠΊΠΎΠ²ΠΎ-синтСтичСской Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΈ эпитСлиоцитов многослойного плоского эпитСлия Π² Π·ΠΎΠ½Π΅ эпидСрмизации ΠΈ ΠΊΠ»Π΅Ρ‚ΠΎΠΊ фибробластичСского ряда Π² краях заТивлСния. Π Π΅ΠΏΠ°Ρ€Π°Ρ‚ΠΈΠ²Π½ΡƒΡŽ Π°ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ ΠΊΡ€Π΅ΠΌΠ° ΠΏΡ€Π΅ΠΆΠ΄Π΅ всСго обСспСчило Π½Π°Π»ΠΈΡ‡ΠΈΠ΅ Ρ‚ΠΈΠΎΠ»ΠΎΠ²Ρ‹Ρ… (ΡΡƒΠ»ΡŒΡ„Π³ΠΈΠ΄Ρ€ΠΈΠ»ΡŒΠ½Ρ‹Ρ…) Π³Ρ€ΡƒΠΏΠΏ Π² ΠΌΠΎΠ»Π΅ΠΊΡƒΠ»Π΅ Π»ΠΈΠΏΠΎΠ΅Π²ΠΎΠΉ кислоты, Ρ‡Ρ‚ΠΎ обСспСчиваСт Π΅ΠΉ свойства антиоксиданта. Антиоксидантный эффСкт Π»ΠΈΠΏΠΎΠ΅Π²ΠΎΠΉ кислоты способствуСт Π±ΠΎΠ»Π΅Π΅ эффСктивной Ρ€Π΅ΠΏΠ°Ρ€Π°Ρ†ΠΈΠΈ ΠΌΠΎΠ»Π΅ΠΊΡƒΠ» Π”ΠΠš послС поврСТдСния Π² Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Π΅ Β«ΠΎΠΊΠΈΡΠ»ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ стрСсса».Π’Ρ‹Π²ΠΎΠ΄Ρ‹. ΠšΡ€Π΅ΠΌ Π”Π΅Ρ€ΠΌΠ°Π»ΠΈΠΏΠΎΠΈΠ½ проявляСт Π²Ρ‹Ρ€Π°ΠΆΠ΅Π½Π½ΠΎΠ΅ Ρ€Π΅ΠΏΠ°Ρ€Π°Ρ‚ΠΈΠ²Π½ΠΎΠ΅ дСйствиС Π·Π° счСт увСличСния Π±Π΅Π»ΠΊΠΎΠ²ΠΎ-синтСтичСской активности ΠΈ ускорСния Ρ€Π΅ΠΏΠ°Ρ€Π°Ρ†ΠΈΠΈ ΠΌΠΎΠ»Π΅ΠΊΡƒΠ» Π”ΠΠš эпитСлиоцитов послС поврСТдСния, Ρ‡Ρ‚ΠΎ проявляСтся ускорСниСм процСсса заТивлСния ΠΎΠΆΠΎΠ³ΠΎΠ².ΠœΠ΅Ρ‚Π° – дослідТСння ΠΌΠ΅Ρ…Π°Π½Ρ–Π·ΠΌΡ–Π² Ρ€Π΅ΠΏΠ°Ρ€Π°Ρ‚ΠΈΠ²Π½ΠΎΡ— Π΄Ρ–Ρ— Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠ±Ρ–Π½ΠΎΠ²Π°Π½ΠΎΠ³ΠΎ ΠΊΡ€Π΅ΠΌΡƒ Π½Π° ΠΌΠΎΠ΄Π΅Π»Ρ– Ρ‚Π΅Ρ€ΠΌΡ–Ρ‡Π½ΠΎΡ— ΠΎΠΏΡ–ΠΊΠΎΠ²ΠΎΡ— Ρ‚Ρ€Π°Π²ΠΌΠΈ Ρƒ Ρ‰ΡƒΡ€Ρ–Π². ΠœΠ°Ρ‚Π΅Ρ€Ρ–Π°Π»ΠΈ Ρ‚Π° ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΈ. На ΠΌΠΎΠ΄Π΅Π»Ρ– Ρ‚Π΅Ρ€ΠΌΡ–Ρ‡Π½ΠΎΠ³ΠΎ ΠΎΠΏΡ–ΠΊΡƒ Ρƒ Ρ‰ΡƒΡ€Ρ–Π² дослідТСні Ρ€Π΅ΠΏΠ°Ρ€Π°Ρ‚ΠΈΠ²Π½Ρ– властивості Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠ±Ρ–Π½ΠΎΠ²Π°Π½ΠΎΠ³ΠΎ ΠΊΡ€Π΅ΠΌΡƒ, ΡƒΠΌΠΎΠ²Π½ΠΎ Π½Π°Π·Π²Π°Π½ΠΎΠ³ΠΎ Β«Π”Π΅Ρ€ΠΌΠ°Π»Ρ–ΠΏΠΎΡ—Π½Β», Π΄ΠΎ складу якого ΡƒΠ²Ρ–ΠΉΡˆΠ»ΠΈ: Ξ±-Π»Ρ–ΠΏΠΎΡ”Π²Π° кислота, сСчовина, ΠΎΠ»ΠΈΠ²ΠΊΠΎΠ²Π° олія, олія Ρ‡Π°ΠΉΠ½ΠΎΠ³ΠΎ Π΄Π΅Ρ€Π΅Π²Π°, ΠŸΠ•Π“-400. Для визначСння рівня Π±Ρ–Π»ΠΊΠΎΠ²ΠΎ-синтСтичної активності ΠΊΠ»Ρ–Ρ‚ΠΈΠ½ (Π΅ΠΏΡ–Ρ‚Π΅Π»Ρ–ΠΎΡ†ΠΈΡ‚Ρ–Π² Π±Π°Π³Π°Ρ‚ΠΎΡˆΠ°Ρ€ΠΎΠ²ΠΎΠ³ΠΎ плоского Π΅ΠΏΡ–Ρ‚Π΅Π»Ρ–ΡŽ Π² Π·ΠΎΠ½Ρ– Π΅ΠΏΡ–Π΄Π΅Ρ€ΠΌΡ–Π·Π°Ρ†Ρ–Ρ— Ρ– ΠΊΠ»Ρ–Ρ‚ΠΈΠ½ фібробластичного ряду Π² краях загоєння Ρ‚Π΅Ρ€ΠΌΡ–Ρ‡Π½ΠΎΠ³ΠΎ пошкодТСння) ΠΏΡ€ΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΈ ΠΎΡ†Ρ–Π½ΠΊΡƒ вмісту Ρ€ΠΈΠ±ΠΎΠ½ΡƒΠΊΠ»Π΅ΠΎΠΏΡ€ΠΎΡ‚Π΅Ρ—Π΄Ρ–Π² Ρƒ Ρ†ΠΈΡ‚ΠΎΠΏΠ»Π°Π·ΠΌΡ– Ρ– дСзоксирибонуклСопротСїдів Ρƒ ядрах ΠΊΠ»Ρ–Ρ‚ΠΈΠ½ ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ Ρ†ΠΈΡ‚ΠΎΡ„ΠΎΡ‚ΠΎΠΌΠ΅Ρ‚Ρ€Ρ–Ρ—.Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚ΠΈ Ρ‚Π° Ρ—Ρ… обговорСння. На ΠΌΠΎΠ΄Π΅Π»Ρ– Ρ‚Π΅Ρ€ΠΌΡ–Ρ‡Π½ΠΎΠ³ΠΎ ΠΎΠΏΡ–ΠΊΡƒ Ρƒ Ρ‰ΡƒΡ€Ρ–Π² ΠΊΡ€Π΅ΠΌ Π”Π΅Ρ€ΠΌΠ°Π»Ρ–ΠΏΠΎΡ—Π½ порівняно Π· ΠΏΡ€Π΅ΠΏΠ°Ρ€Π°Ρ‚Π°ΠΌΠΈ порівняння – маззю ΠΌΠ΅Ρ‚ΠΈΠ»ΡƒΡ€Π°Ρ†ΠΈΠ»ΠΎΠ²ΠΎΡŽ Ρ‚Π° Π³Π΅Π»Π΅ΠΌ Π’Ρ–Ρ‚Ρ€Ρ–ΠΎΠ» виявив Π±Ρ–Π»ΡŒΡˆ Π°ΠΊΡ‚ΠΈΠ²Π½ΠΈΠΉ Π²ΠΏΠ»ΠΈΠ² Π½Π° Ρ€Π΅ΠΏΠ°Ρ€Π°Ρ‚ΠΈΠ²Π½Ρ– процСси, ΠΏΡ€ΠΎ Ρ‰ΠΎ свідчило Π²Ρ–Ρ€ΠΎΠ³Ρ–Π΄Π½Π΅ Π·Π±Ρ–Π»ΡŒΡˆΠ΅Π½Π½ΡΒ  Π±Ρ–Π»ΠΊΠΎΠ²ΠΎ-синтСтичної Ρ„ΡƒΠ½ΠΊΡ†Ρ–Ρ— Π΅ΠΏΡ–Ρ‚Π΅Π»Ρ–ΠΎΡ†ΠΈΡ‚Ρ–Π² Π±Π°Π³Π°Ρ‚ΠΎΡˆΠ°Ρ€ΠΎΠ²ΠΎΠ³ΠΎ плоского Π΅ΠΏΡ–Ρ‚Π΅Π»Ρ–ΡŽ Π² Π·ΠΎΠ½Ρ– Π΅ΠΏΡ–Π΄Π΅Ρ€ΠΌΡ–Π·Π°Ρ†Ρ–Ρ— Ρ– ΠΊΠ»Ρ–Ρ‚ΠΈΠ½ фібробластичного ряду Π² краях загоєння. Π Π΅ΠΏΠ°Ρ€Π°Ρ‚ΠΈΠ²Π½Ρƒ Π°ΠΊΡ‚ΠΈΠ²Π½Ρ–ΡΡ‚ΡŒ ΠΊΡ€Π΅ΠΌΡƒ, насампСрСд, Π·Π°Π±Π΅Π·ΠΏΠ΅Ρ‡ΠΈΠ»Π° Π½Π°ΡΠ²Π½Ρ–ΡΡ‚ΡŒ Ρ‚Ρ–ΠΎΠ»ΠΎΠ²ΠΈΡ… (ΡΡƒΠ»ΡŒΡ„Π³Ρ–Π΄Ρ€ΠΈΠ»ΡŒΠ½ΠΈΡ…) Π³Ρ€ΡƒΠΏ Ρƒ ΠΌΠΎΠ»Π΅ΠΊΡƒΠ»Ρ– Π»Ρ–ΠΏΠΎΡ”Π²ΠΎΡ— кислоти, Ρ‰ΠΎ Π½Π°Π΄Π°Ρ” Ρ—ΠΉ властивості антиоксиданта. Антиоксидантний Π΅Ρ„Π΅ΠΊΡ‚ Π»Ρ–ΠΏΠΎΡ”Π²ΠΎΡ— кислоти сприяє Π±Ρ–Π»ΡŒΡˆ Π΅Ρ„Π΅ΠΊΡ‚ΠΈΠ²Π½Ρ–ΠΉ Ρ€Π΅ΠΏΠ°Ρ€Π°Ρ†Ρ–Ρ— ΠΌΠΎΠ»Π΅ΠΊΡƒΠ» Π”ΠΠš після пошкодТСння Π² Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ– «окисного стрСсу». Висновки. ΠšΡ€Π΅ΠΌ Π”Π΅Ρ€ΠΌΠ°Π»Ρ–ΠΏΠΎΡ—Π½ Ρ‡ΠΈΠ½ΠΈΡ‚ΡŒ Π²ΠΈΡ€Π°Π·Π½Ρƒ Ρ€Π΅ΠΏΠ°Ρ€Π°Ρ‚ΠΈΠ²Π½Ρƒ Π΄Ρ–ΡŽ Π·Π° Ρ€Π°Ρ…ΡƒΠ½ΠΎΠΊ Π·Π±Ρ–Π»ΡŒΡˆΠ΅Π½Π½Ρ Π±Ρ–Π»ΠΊΠΎΠ²ΠΎ-синтСтичної активності Ρ‚Π° прискорСння Ρ€Π΅ΠΏΠ°Ρ€Π°Ρ†Ρ–Ρ— ΠΌΠΎΠ»Π΅ΠΊΡƒΠ» Π”ΠΠš Π΅ΠΏΡ–Ρ‚Π΅Π»Ρ–ΠΎΡ†ΠΈΡ‚Ρ–Π² після пошкодТСння, Ρ‰ΠΎ ΠΏΡ€ΠΎΡΠ²Π»ΡΡ”Ρ‚ΡŒΡΡ прискорСнням процСсу загоєння ΠΎΠΏΡ–ΠΊΡ–Π²

    Optimization of the sintering parameters for materials manufactured by powder injection molding

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    Translated from Poroshkova Metallurgiya, Vol. 59, Nos. 1–2 (531), pp. 32–41, 2020. Original article submitted September 13, 2019.The properties of sintered and heat-treated steels produced from the Catamold 8740 material by powder injection molding were examined. Parts made of the Catamold 8740 low-alloy mild carbon steel are used in the military, automotive, and other industries where high reliability and resistance to dynamic loads are required. The Catamold 8740 chemical homogeneity was studied as a function of powder injection molding parameters: heating rate, sintering temperature, holding time, and subsequent heat treatment. Microscopic analysis showed that Catamold 8740 was a mechanical mixture of powders in various sizes (carbonyl iron, nickel, Fe–Mo, Fe–Cr, Fe–Si-Mo, Fe–Si). When the heating rate of the Catamold 8740 powder mixture increased from 2 to 5 Β°C/min, the microstructural heterogeneity caused by uneven compaction decreased and the alloy formation process activated at 900–1340Β°C. The impact strength of Charpy V-notch test samples changed from 10.39 to 11.52 J/cm2 with higher sintering temperature and heating rate increasing from 2 Β°C/min (1270Β°C) to 5 Β°C/min (1340Β°C). When holding time increased from 30 to 90 min at a sintering temperature of 1340Β°C, the material became denser, the pores rounded, and the ferrite matrix homogeneous. However, the impact strength decreased by a factor of 1.4 because of coarser grain sizes and brittle fracture. Heat treatment processes reduced the impact strength after sintering. The results obtained were used to optimize the powder injection molding parameters. The influence of chemical and dimensional inhomogeneity of the starting Catamold 8740 powders and sintering kinetics on the structure and mechanical properties of parts operating under impact loads was established

    Macro- and microelements determination in children with rotavirus infection

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    The purpose of this study was to determine serum zinc, iron, magnesium, copper, potassium, calcium, and sodium levels in acute rotavirus infection and convalescence period in children. Materials and methods. We examined 86 patients aged from 4 months to 5 years with clinical and laboratory signs of rotavirus infection. The I group – 43 children with RVI in acute period. The II group – 43 children with RVI in convalescence period. The control group included 14 healthy children at the same age. The content of macro- and microelements (zinc, iron, magnesium, copper, potassium, calcium and sodium) in blood serum was determined by atomic absorption spectrophotometry. Feces samples were used for Cito Test Rota (Pharmasco). Cito test was used for rotavirus antigen detection in feces. Statistical analysis was performed by Excel. Student’s t-test was used to evaluate differences between study groups. Results. The acute period of the disease in children with rotavirus infection was characterized by a significant increase of copper in blood serum compared with the control group. At the same time, a significant decrease of iron, magnesium, zinc, potassium, calcium, sodium were determined in patients with rotavirus infection, compared with apparently healthy children. After standard treatment only the indicators of magnesium, potassium and sodium reached the same indices of control group children. Conclusions. The detected changes in the mineral status of patients with rotavirus infection suggest the need for treatment correction. Correction of micro- and macroelements imbalances in patients with rotavirus infection possibly should be aimed at the metallo-drugs inclusion in complex treatment as well as medicines which improve absorption of the latter in the intestine

    Recommendations of the Ukrainian Renal Disaster Relief Committee of the Ukrainian Association of Nephrologists and Kidney Transplant Specialists regarding medical care to kidney disease patients during the war

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    Abstract. The occurrence of an emergency situation (ES) forced international (ISN, EDTA/ERA) and national (Turkey) nephrological associations to establish the Renal Disaster Relief Task Force, which is primarily concerned with the treatment of patients with acute kidney injury and end-stage renal disease requiring dialysis. The war started by the RF is putting the Ukrainian state, Ukrainian society, and the healthcare system in the catastrophic ES. Under these circumstances, all nephrological patients became one of the most vulnerable categories of patients. To provide immediate support in solving problems within the Ukrainian Association of Nephrologists and Kidney Transplant Specialists (UAN&KTS), the Ukrainian Renal Disaster Relief Committee (URDRC) has been established. One of the most important tasks was to form a group of experts to develop recommendations for specialized medical care for kidney patients in wartime. Β According to the experts, the key person for this type of medical care is the leading nephrologist in the region or city. He/she establishes a local Renal Disaster Relief Committee (LRDRC) and decides through horizontal (with other LRDRC) or vertical (with UAN &KTS) collaboration, using available communication tools, on the problems that arise; the most appropriate tool is the Viber platform "Nephrology. Dialysis. Transplantation". In this way, a network without administrative subordination and a non-hierarchical functional system was created, which, on the one hand, functions according to similar working principles, but, on the other hand, may differ in terms of LRDRC composition, communication methods, and more. The LRDRC divides all patients into three groups and provides work preparation measures before, during and after the cancellation of ES

    Northern Eurasia Future Initiative (NEFI): facing the challenges and pathways of global change in the twenty-first century

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    Β© 2017, The Author(s). During the past several decades, the Earth system has changed significantly, especially across Northern Eurasia. Changes in the socio-economic conditions of the larger countries in the region have also resulted in a variety of regional environmental changes that can have global consequences. The Northern Eurasia Future Initiative (NEFI) has been designed as an essential continuation of the Northern Eurasia Earth Science Partnership Initiative (NEESPI), which was launched in 2004. NEESPI sought to elucidate all aspects of ongoing environmental change, to inform societies and, thus, to better prepare societies for future developments. A key principle of NEFI is that these developments must now be secured through science-based strategies co-designed with regional decision-makers to lead their societies to prosperity in the face of environmental and institutional challenges. NEESPI scientific research, data, and models have created a solid knowledge base to support the NEFI program. This paper presents the NEFI research vision consensus based on that knowledge. It provides the reader with samples of recent accomplishments in regional studies and formulates new NEFI science questions. To address these questions, nine research foci are identified and their selections are briefly justified. These foci include warming of the Arctic; changing frequency, pattern, and intensity of extreme and inclement environmental conditions; retreat of the cryosphere; changes in terrestrial water cycles; changes in the biosphere; pressures on land use; changes in infrastructure; societal actions in response to environmental change; and quantification of Northern Eurasia’s role in the global Earth system. Powerful feedbacks between the Earth and human systems in Northern Eurasia (e.g., mega-fires, droughts, depletion of the cryosphere essential for water supply, retreat of sea ice) result from past and current human activities (e.g., large-scale water withdrawals, land use, and governance change) and potentially restrict or provide new opportunities for future human activities. Therefore, we propose that integrated assessment models are needed as the final stage of global change assessment. The overarching goal of this NEFI modeling effort will enable evaluation of economic decisions in response to changing environmental conditions and justification of mitigation and adaptation efforts
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