Comparison of early reactions of the blood system in rats to immobilization, the action of hypoxia and the administration of erythopoietin

Three series of experiments were simultaneously carried on rats with the purpose of studying the action of different stimulants on the blood system; rats were subjected to immobilization, hypoxic hypoxia and erythropoietin administration. Changes in various cellular forms in the bone marrow, the thymus and the spleen were studied. A unitypical reaction, as in stress, was noted during the first hours; a reduction of the cell count in the lymphoid organs, a reduction of granulocytes and an increase of lymphoid cells in the bone marrow. The differences were chiefly quantitative. This was followed by stimulation of myelo and erythropoiesis determined by the specific features of the action applied. Nonspecific blood reaction was apparently due to activation of the adaptation mechanisms

Study of the associations between polymorphic markers rs1800629 TNFα, rs909253 Ltα, rs767455 TNFR1, rs1061624 TNFR2 and the development of type 2 diabetes = Изучение ассоциаций полиморфных маркеров генов факторов некроза опухоли и их рецепторов rs1800629 TNFα, rs909253 Ltα, rs767455 TNFR1, rs1061624 TNFR2 с формированием сахарного диабета 2 типа

To study the association between polymorphic genetic markers, tumor necrosis factors and their receptors (rs 1800629 TNFα, rs 909253 Ltα, rs 767455 TNFR1, rs 1061624 TNFR2) and the development of type 2 diabetes (T2D) among the population of the Central Black Earth Region of Russi

Peculiarities of Intersystemic Correlation Relationships of M-Response and F-Wave Characteristics in the Forearms Symmetric Muscles Which Participate in the Implementation of Multiple Coordinated Bimanual Movements

The organization of combined voluntary goal directed movements of hands has remained a serious scientific problem with a pronounced applicable nature.  Insufficiency of a procedural framework and clear quantitative and qualitative criteria causes gaps and difficulties in professional selection, the effectiveness diagnosis of work-out session in sports and rehabilitation within remedial treatment.  The aim of the investigation is to study the adjustment and co-adjustment of the effector apparatus elements, which are the basis of bimanual coordination, in the groups of male and female trial subjects. In the following study, based on informed consent in accordance with the ethics committee requirements, 75 subjects (39 men and 36 women) at the age of 18-20 took part. F-wave and M-response parameters registration was carried out by means of NMA-4-01 “NEUROMIAN” neuromyoanalyzer (Taganrog, Russia) according to the standard method. It has been established that the nerve centers responsible for the work of homonymous muscles in the right and left forearms, innervating synergists and antagonists, are to a certain extent in the initial adjustment and co-adjustment according to the level of activity, which determines not only the moment of the excitement onset, but also the speed of its irradiation.  The revealed manifestations of adjustment and co-adjustment have pronounced sex differences.  Proceeding from the fact that female trial subjects have a lower level of bimanual movements if compared with men, it can be assumed that the revealed features of correlational relationships determine, to a certain extent, coordination abilities of men and women

Peculiarities of Intersystemic Correlation Relationships of M-Response and F-Wave Characteristics in the Forearms Symmetric Muscles Which Participate in the Implementation of Multiple Coordinated Bimanual Movements

The organization of combined voluntary goal directed movements of hands has remained a serious scientific problem with a pronounced applicable nature.  Insufficiency of a procedural framework and clear quantitative and qualitative criteria causes gaps and difficulties in professional selection, the effectiveness diagnosis of work-out session in sports and rehabilitation within remedial treatment.  The aim of the investigation is to study the adjustment and co-adjustment of the effector apparatus elements, which are the basis of bimanual coordination, in the groups of male and female trial subjects. In the following study, based on informed consent in accordance with the ethics committee requirements, 75 subjects (39 men and 36 women) at the age of 18-20 took part. F-wave and M-response parameters registration was carried out by means of NMA-4-01 “NEUROMIAN” neuromyoanalyzer (Taganrog, Russia) according to the standard method. It has been established that the nerve centers responsible for the work of homonymous muscles in the right and left forearms, innervating synergists and antagonists, are to a certain extent in the initial adjustment and co-adjustment according to the level of activity, which determines not only the moment of the excitement onset, but also the speed of its irradiation.  The revealed manifestations of adjustment and co-adjustment have pronounced sex differences.  Proceeding from the fact that female trial subjects have a lower level of bimanual movements if compared with men, it can be assumed that the revealed features of correlational relationships determine, to a certain extent, coordination abilities of men and women

Peculiarities of Intersystemic Correlation Relationships of M-Response and F-Wave Characteristics in the Forearms Symmetric Muscles Which Participate in the Implementation of Multiple Coordinated Bimanual Movements

The organization of combined voluntary goal directed movements of hands has remained a serious scientific problem with a pronounced applicable nature.  Insufficiency of a procedural framework and clear quantitative and qualitative criteria causes gaps and difficulties in professional selection, the effectiveness diagnosis of work-out session in sports and rehabilitation within remedial treatment.  The aim of the investigation is to study the adjustment and co-adjustment of the effector apparatus elements, which are the basis of bimanual coordination, in the groups of male and female trial subjects. In the following study, based on informed consent in accordance with the ethics committee requirements, 75 subjects (39 men and 36 women) at the age of 18-20 took part. F-wave and M-response parameters registration was carried out by means of NMA-4-01 “NEUROMIAN” neuromyoanalyzer (Taganrog, Russia) according to the standard method. It has been established that the nerve centers responsible for the work of homonymous muscles in the right and left forearms, innervating synergists and antagonists, are to a certain extent in the initial adjustment and co-adjustment according to the level of activity, which determines not only the moment of the excitement onset, but also the speed of its irradiation.  The revealed manifestations of adjustment and co-adjustment have pronounced sex differences.  Proceeding from the fact that female trial subjects have a lower level of bimanual movements if compared with men, it can be assumed that the revealed features of correlational relationships determine, to a certain extent, coordination abilities of men and women

Assessment of the quality of life in elderly and senile age patients with chronic heart failure

The present study aimed to compare the QOL in patients with heart failure with mid-range ejection fraction (HFmrEF) in different age groups, taking into account gender difference

Terminology pediatrics

The article analyzes the modern terminology of Pediatrics. We have identified thematic groups and specific Latin names specific to Pediatrics. We have analyzed the Latin names; defined their structure, defined the variety of terms. We also conducted an etymological and contrastive analysis with Russian Federationn terms, noted their similarity and difference. Special attention is paid to specific Russian Federationn names, which are firmly entrenched in the language of medicine.В статье анализируется современная терминология педиатрии. Нами были выявлены тематические группы и специфические латинские названия, характерные для педиатрии. Нами был проведен анализ латинских названий; определена их структура, определены разновидности терминов. Мы также провели этимологический и контрастивный анализ с русскими терминами, отметили их схожесть и различие. Особое внимание уделяется специфическим русским названиям, которые прочно закрепились в языке медицины

FEATURES OF LATE PRETERM INFANTS IN THE CONDITIONS OF THE REGIONAL PERINATAL CENTER

The purpose of the study was to investigate the main factors predisposing to the birth of children at gestational age of 34–36 weeks, the features of the course of the neonatal period, the structure of morbidity and mortality in the conditions of the regional perinatal center. Material and methods. A retrospective analysis of 380 medical records of an inpatient patient of the Regional Perinatal Center of State Novosibirsk Regional Clinical Hospital born on a gestational age of 34–36 weeks for 2017–2018 was performed. Results and discussion. All women with premature late delivery had a burdened somatic and/or obstetric-gynecological history. 70 % of women were delivered by surgery. The anthropometric characteristics of late preterm infants in 85 % of cases corresponded to gestational age, in most of them the neonatal period proceeded with the development of respiratory disorders, hyperbilirubinemia, and low tolerance to enteral nutrition. Children with less gestational age needed respiratory support for a longer time. Due to the difficult condition at birth, about 40 % of the children were transferred from the maternity ward to the intensive care unit of the newborn. A quarter of late premature infants received medical care exclusively in a maternity hospital. The mortality rate was 1 %. Thus, late premature babies are a special category of newborns, when nursing which it is necessary to carry out timely diagnosis of pathological conditions, as well as the prevention of adaptation disorders, especially in the early neonatal period

Society and the state in the pandemic context

Based on the importance of an unprecedented new reality, the authors were tasked with studying and analyzing the problems of interaction between the State and society in the context of the pandemic and the introduction of state measures to prevent the spread of viral infection, which to a degree or another limit the rights and freedoms of a person and citize

Use of a neural network in creating a digital assistant for blind and visually impaired people

The experience of ongoing research in image processing clearly demonstrates the huge scope for the development of new neural networks that can help people in a wide range of tasks. The authors chose the direction of work related to helping people who have vision problems. The article considers a convolutional neural network of the Mask R-CNN model for segmenting objects in an image. During the research the authors study a large number of algorithms that can quickly and accurately process images, such as Faster R-CNN, which was the most efficient in 2020. During the analysis, it was revealed that the use of Mask R-N technology can significantly increase the efficiency of performing tasks, since this algorithm is the latest version of the machine learning model. As a result of the study, a neural network was developed that is capable of identifying and distinguishing a large number of objects in an image. The next step is to refine the algorithm and use additional means of interaction with the hardware of the systems to increase the speed of the neural network. In the future, the resulting neural network will be integrated into the Digital Assistant for the Blind and Visually Impaired Persons application. This application is guaranteed to improve the daily life of people with disabilities who experience certain inconveniences due to their features, and can become the basis for other, larger projects related, for example, to unmanned devices, as well as services whose work is directly based on image processing