COMPLEX ACTION METHODOLOGY FOR ENTERPRISE SYSTEMS (CAMES): AN EXPERIMENTAL ACTION RESEARCH INQUIRY INTO COMMUNICATIVE ACTION AND QUANTUM MECHANICS FOR ACTION RESEARCH FIELD STUDIES IN ORGANISATIONAL CONTEXT

Current action research methodologies bias observations severely and render quantification models of subjective data uncertain. Thus, this research thesis aims to design a scientifically rigorous action-science methodology process that establishes a subject-bias-free method for communication in an organisational context. This investigation aims to apply scientific rigour to this issue and to verify the general applicability of mathematical formalism of quantum mechanics to address organisational venture that includes a “wicked problem” (Stubbart, 1987, quoted in Pearson and Clair, 1998, p. 62) of how to communicate and collaborate appropriately. The subjective data collection and quantification models of this thesis build on the quantitative formalism of quantum mechanics and qualitative formalism of the theory of communicative action. Mathematical and ontological formalism combine into a novel research strategy with planned instrumentation for action research field studies summarised under the term ‘Complex Action Methodology for Enterprise Systems’ (CAMES). The outcome is a process to understand the behavioural action of organisational members. This process is not technical, and neither does it involve a machine or apparatus. The process is primarily mathematical and requires that participants act under a new identity, a virtual identity. Similarly, the data analysis does not require a specific machine, technology or an apparatus. A spreadsheet calculator will primarily be sufficient for low entry. Data collection occurs in one block with an average duration time of 10 minutes in a virtual location. The practice can, therefore, use this thesis’ procedures for bias-free quantification of subjective data and prediction of an individual’s future behaviour with certainty. Prediction of an individual’s future behaviour with certainty provides to the organizational practice what organisational practice lacks but urgently requires. The certainty that claimed findings of behaviour in organisational context requires to intervene and steer. Certainty and justification for planned intervening and steering initiatives secure funding

Quantification of airborne road-side pollution carbon nanoparticles

Roadside diesel particulate matter (DPM) has been collected using a P-Trak particle counter with modified inlet filter. The P-Trak monitor assesses ultrafine particle number in real-time rather than accumulated PM mass over a period of time, which is important for DPM where the particles are often <100nm in size. Collected pollution particulate matter was analysed by SEM and TEM, quantifying particle size, morphology and size distribution. The primary carbon nanoparticles form complex fractal aggregates with open porous morphologies and evidence of secondary carbon deposition. For the chosen collection sites, occasional but significantly larger mineral and fibrous particles were identified. The assessment of airborne particles by mass collection (TEOM), particle-number (P-Trak) and TEM methods is discussed

A sustainable food support for non-breastfed infants : implementation and acceptability within a WHO mother-to-child HIV transmission prevention trial in Burkina Faso

Objective: To provide HIV-positive mothers who opted for exclusive breastfeeding or formula feeding from birth to 6 months postpartum as a means of prevention of mother-to-child transmission (PMTCT) of HIV with a sustainable infant food support programme (FSP) from 6 to 12 months postpartum. We describe the implementation and assessment of this pilot initiative. Design: The FSP included a 6-month provision of locally produced infant fortified mix (IFM; 418 kJ/100 g of gruel) for non-breastfed infants coupled with infant-feeding and psychosocial counselling and support. Acceptability and feasibility were assessed in a subsample of sixty-eight mother-infant pairs. Setting: The FSP was developed in collaboration with local partners to support. participants in a PMTCT prevention study. Formula WAS provided for free from 0 to 6 months postpartum. Cessation by 6 months was recommended for breast feeding mothers. Results: The FSP was positively received and greatly encouraged breastfeeding mothers to cease by 6 months. As recommended, most infants were given milk as an additional replacement food, mainly formula subsidised by safety networks. Among daily IFM consumers, feeding practices were satisfactory overall; however, the IFM was shared within the family by more than one-third of the mothers. Cessation of IFM consumption was observed among twenty-two infants, seventeen of whom were fed milk and five neither of these. Conclusions: Without any food support most mothers would have been unable to provide appropriate replacement feeding. The food security of non-breastfed infants urgently needs to be addressed in HIV PMTCT programmes. Our findings on a simple cost-effective pioneer intervention provide an important foundation for this process

Innovative Ansaetze zur Schaffung von Arbeitsplaetzen im Umweltschutz Endbericht

Current environmental policies substantially contribute to the creation and security of employment opportunities. However, a specifically employment oriented environmental policy might stimulate job creation even more. This study assesses various sub-markets of the environmental protection sector, develops suggestions for job creating measures, and describes the obstacles of as well as estimations for the job creating potential of an innovative environmental policy. (orig.)SIGLEAvailable from TIB Hannover: RN 8908(2000,490) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekBundesministerium fuer Umwelt, Naturschutz und Reaktorsicherheit, Bonn (Germany)DEGerman

Amodiaquine Dosage and Tolerability for Intermittent Preventive Treatment To Prevent Malaria in Children ▿ †

Sulfadoxine-pyrimethamine with amodiaquine (SP-AQ) is a highly efficacious regimen for intermittent preventive treatment to prevent malaria in children (IPTc), but the amodiaquine component is not always well tolerated. We determined the association between amodiaquine dosage by body weight and mild adverse events (AEs) and investigated whether alternative age-based regimens could improve dosing accuracy and tolerability, using data from two trials of IPTc in Senegal, one in which AQ dose was determined by age and the other in which it was determined by weight category. Both dosage strategies resulted in some children receiving AQ doses above the recommended therapeutic range. The odds of vomiting increased with increasing amodiaquine dosage. In one study, incidence of fever also increased with increasing dosage. Anthropometric data from 1,956 children were used to predict the dosing accuracy of existing and optimal alternative regimens. Logistic regression models describing the probability of AEs by dosage were used to predict the potential reductions in mild AEs for each regimen. Simple amendments to current AQ dosing schedules based on the child's age could substantially increase dosing accuracy and thus improve the tolerability of IPTc using SP-amodiaquine in situations where weighing the child is impractical

Effects of malnutrition on children's immunity to bacterial antigens in Northern Senegal

To evaluate immunity to vaccine-preventable diseases according to nutritional status, a longitudinal study was conducted in Senegalese children ages 1-9 years old. A linear regression analysis predicted that weight for age was positively associated with immunoglobulin G (IgG) response to tetanus toxoid in children born during the rainy season or at the beginning of the dry season. A relationship between village, time of visits, and levels of antibodies to tetanus showed that environmental factors played a role in modulating humoral immunity to tetanus vaccine over time. Moreover, a whole-blood stimulation assay highlighted that the production of interferon-gamma (IFN-gamma) in response to tetanus toxoid was compromised in stunted children. However, the absence of cytokine modulation in response to Mycobacterium tuberculosis-purified protein derivatives and phytohemagglutinin suggests that the overall ability to produce IFN-gamma was preserved in stunted children. Therefore, these results show that nutritional status can specifically alter the efficacy of long-lasting immunity to tetanus

Equitable mitigation to achieve the Paris Agreement goals

Benchmarks to guide countries in ratcheting-up ambition, climate finance, and support in an equitable manner are critical but not yet determined in the context of the Paris Agreement1. We identify global cost-optimal mitigation scenarios consistent with the Paris Agreement goals and allocate their emissions dynamically to countries according to five equity approaches. At the national level, China's Nationally Determined Contribution (NDC) is weaker than any of the five equity approaches, India's and the USA's NDC are aligned with two, and the EU's with three. Most developing countries’ conditional (Intended) NDCs (INDCs) are more ambitious than the average of the five equity approaches under the 2 °C goal. If the G8 and China adopt the average of the five approaches, the gap between conditional INDCs and 2 °C-consistent pathways could be closed. For an equitable, cost-optimal achievement of the 1.5 °C target, emissions in 2030 are 21% lower (relative to 2010) than for 2 °C for the G8 and China combined, and 39% lower for remaining countries. Equitably limiting warming to 1.5 °C rather than 2 °C requires that individual countries achieve mitigation milestones, such as peaking or reaching net-zero emissions, around a decade earlier