87 research outputs found

    Volatile components and continental material of planets

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    It is shown that the continental material of the terrestrial planets varies in composition from planet to planet according to the abundances and composition of true volatiles (H20, CO2, etc.) in the outer shells of the planets. The formation of these shells occurs very early in a planet's evolution when the role of endogenous processes is indistinct and continental materials are subject to melting and vaporizing in the absence of an atmosphere. As a result, the chemical properties of continental materials are related not only to fractionation processes but also to meltability and volatility. For planets retaining a certain quantity of true volatile components, the chemical transformation of continental material is characterized by a close interaction between impact melting vaporization and endogeneous geological processes

    Value of the labour in the hierarchy of values among youth

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    В данной статье рассмотрено место труда в общей структуре ценностей казахстанской молодежи. За эмпирическую основу взяты данные социологического исследования, проведенного научно-исследовательским центром «Молодежь» в августе 2016 г.In this article regarded role of the labour in the hierarchy of values among youth in Kazakhstan. Empirical data based on sociological research conducted in August 2016

    Influence of the chronic stress of pregnant rats on their offspring’s morpho-functional liver condition

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    The morphofunctional state of the rats offspring liver, born from femal rats underwent chronic immobilization stress during pregnancy was studied. It has been revealed that chronic stress in female rats during pregnancy wields considerable influence over liver morphology and lipid-synthesizing function of their offspring. Pronounced discomplexing of the beam-radiary structure, increase of stromal - parenchymal index due to increase in stromal and decrease in the parenchymal components of the liver and decrease level of expression of endothelial synthase has been morphologically revealed. Biochemical study of the liver homogenate revealed signs of impaired synthesis, secretion and reuptake of lipids (increase of cholesterol, tryglyceerids and non-esterified fatty acids and decrease of phospholipids. In the offsprings blood serum dyslipidemia (increase of cholesterol and low-density lipoproteins level) was detected. All this is a risk factor for fibrosis, fatty hepatosis and level cirrhosis development

    СУЧАСНІ ПОГЛЯДИ НА ВИКЛАДАННЯ ПАТОФІЗІОЛОГІЇ ДЛЯ БАКАЛАВРІВ МЕДИЦИНИ

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    Future Specialist - Bachelor of Medicine - should get a certain amount of knowledge of pathophysiology that would meet the requirements of modern medical practice. To achieve this, it is offered to intensify cognitive activities, to combine theoretical and practical training for more in-depth understanding of students on general and specific pathophysiology and increase the possibility of using their acquired knowledge.Майбутній фахівець – бакалавр медицини – повинен отримати певний обсяг знань з патологічної фізіології, що б відповідав вимогам сучасної медичної практики. Для досягнення цього пропонується активізувати пізнавальну діяльність, об’єднати теоретичну та практичну підготовку для більш поглибленого розуміння студентами питань загальної й спеціальної патофізіології та підвищення можливості використання набутих ними знань

    Influence of college of pontiffs on public life in the roman republic in VI-I centuries BC

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    © Serials Publications. The relevance of the problem discussed in the paper is predetermined by the necessity to carry a systemic research on the functions performed by the College of Pontiffs (Collegium Pontificum) for profound understanding of mechanisms and principles how various spheres of public life functioned in the Roman Republic which allows us to conduct a more precise reconstruction of the events during the Republican Period. The aim of the paper is to estimate the degree of the influence of the College of Pontiffs on public life of the Roman Republic. The leading approach to the investigation is the systemic analysis of historical resources and literature which allow to conduct a deep and multifaceted research on the functions of the College of Pontiffs and to make trustworthy conclusions on the role of the College in life of Rome during the Republican Period. The main results of the investigation reside in the assessment of the role the College played in public life of Roman citizens during the Republican Period. The authors single out the spheres of life in which the pontifices participated most actively, and which, as opposed to any other religious college, they had the biggest influence on

    Fourier transform spectroscopy and coupled-channel deperturbation treatment of the A1Sigma+ ~ b3Pi complex of KCs molecule

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    The laser induced fluorescence (LIF) spectra A1Sigma ~ b3Pi --> X1Sigma+ of KCs dimer were recorded in near infrared region by Fourier Transform Spectrometer with a resolution of 0.03 cm-1. Overall more than 200 LIF spectra were rotationally assigned to 39K133Cs and 41K133Cs isotopomers yielding with the uncertainty of 0.003-0.01 cm-1 more than 3400 rovibronic term values of the strongly mixed singlet A1Sigma+ and triplet b3Pi states. Experimental data massive starts from the lowest vibrational level v_A=0 of the singlet and nonuniformly cover the energy range from 10040 to 13250 cm-1 with rotational quantum numbers J from 7 to 225. Besides of the dominating regular A1Sigma+ ~ b3P Omega=0 interactions the weak and local heterogenous A1S+ ~ b3P Omega=1 perturbations have been discovered and analyzed. Coupled-channel deperturbation analysis of the experimental 39K133Cs e-parity termvalues of the A1S+ ~ b3P complex was accomplished in the framework of the phenomenological 4 x 4 Hamiltonian accounting implicitly for regular interactions with the remote states manifold. The resulting diabatic potential energy curves of the interacting states and relevant spin-orbit coupling matrix elements defined analytically by Expanded Morse Oscillators model reproduce 95% of experimental data field of the 39K133Cs isotopomer with a standard deviation of 0.004 cm-1 which is consistent with the uncertainty of the experiment. Reliability of the derived parameters was additionally confirmed by a good agreement between the predicted and experimental termvalues of 41K133Cs isotopomer. Calculated intensity distributions in the A ~ b --> X LIF progressions are also consistent with their experimental counterparts.Comment: 17 pages, 14 figure

    Динаміка морфофункціональних зрушень підшлункової залози та рівень цитокинів у потомства щурів внаслідок дії хронічного стресу = The dynamics of the morphofunctional changes of the offspring-rats’ pancreases and level of cytokinins resulting from an action of the chronic stress

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    Nikolayeva O., Pavlova E., Sirenko V., Kovaltsova M., Sulhdost I. Динаміка морфофункціональних зрушень підшлункової залози та рівень цитокинів у потомства щурів внаслідок дії хронічного стресу = The dynamics of the morphofunctional changes of the offspring-rats’ pancreases and level of cytokinins resulting from an action of the chronic stress. Journal of Education, Health and Sport. 2016;6(6):279-290. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.55416http://ojs.ukw.edu.pl/index.php/johs/article/view/3578 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015).755 Journal of Education, Health and Sport eISSN 2391-8306 7© The Author (s) 2016;This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercialuse, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 05.05.2016. Revised 25.05.2016. Accepted: 10.06.2016. УДК 616.37–091.8–092.9:613.24/.25:613.65:612.015.11 ДИНАМІКА МОРФОФУНКЦІОНАЛЬНИХ ЗРУШЕНЬ ПІДШЛУНКОВОЇ ЗАЛОЗИ ТА РІВЕНЬ ЦИТОКИНІВ У ПОТОМСТВА ЩУРІВ ВНАСЛІДОК ДІЇ ХРОНІЧНОГО СТРЕСУ О. В. Ніколаєва, О. О. Павлова, В. А. Сіренко, М. В. Ковальцова, І. О. Сулхдост Харківський національний медичний університет. Харків. Україна  The Dynamics Of The Morphofunctional Changes Of The Offspring-Rats’ Pancreases and Level Of Cytokinins Resulting From An Action Of The Chronic Stress O. Nikolayeva, E. Pavlova, V. Sirenko, M. Kovaltsova, I. Sulhdost Kharkiv National Medical University, Kharkov, Ukraine Introduction. The pathology of the pancreas caused by the stress is an actual problem of medicine. The purpose of the study was describe of characteristics morphofunctional state of the pancreas of babe-rats’ and to analyzed pro-inflammatory and anti-inflammatory cytokines balance. Materials and Methods. We studied morphological changes of pancreas of offspring-rats’ using histological, cytochemical, cytomorphometric and biochemical methods. We studied immunological status using biochemical methods. We studied the level of interleukin-12 and interleukin-4 in the blood. The core group of mother-rats was exposed to chronic stress immobilization. The comparison group consisted of animals that led ordinary life. For the rats, the experiment was stopped immediately after the birth of offspring in compliance with the ethical principles. Results. Stress during pregnancy in rats affects the morphology and function of the pancreas in the offspring. Symptoms of morphofunctional disorders are obvious even in the pancreas of newborn rats. There are reduced acini and islets of Langerhans, immaturity parenchymal area, edema, fibrosis, degenerative changes in the nuclei and cytoplasm exocrine and endocrine cells, decrease morphofunctional state of the same part of pancreas cell, violation of geodynamics. Most of them not only saves up until they are two months of age, but has a negative trend of growth severity: reducing the relative amount of parenchymal acini area, number and area of the islets of Langerhans, the number of endocrine cells in them, apiaries lipomatosis stroma. We also noticed simultaneous launch of compensatory-adaptive processes in the endocrine pancreas in the form of hypertrophy of single islets of Langerhans. The rats in all groups are diagnosed as having identical tendencies of cytokines change; significant buildup of pro-inflammatory interleukin-12 and reduction of anti-inflammatory interleukin-4 which indicates predominant involvement in pathogenesis of violation of pancreas cell component of immune system. Conclusions. The results suggest that chronic stress of pregnant rats is a significant risk factor for future chronic pathology of the pancreas rats-offspring.Keywords: chronic stress immobilization, pancreas, rats, interleukin, experiment. ДИНАМИКА МОРФОФУНКЦИОНАЛЬНЫХ НАРУШЕНИЙ ПОДЖЕЛУДОЧНОЙ ЖЕЛЕЗЫ И УРОВЕНЬ ЦИТОКИНОВ У ПОТОМСТВА КРЫС ВСЛЕДСТВИЕ ДЕЙСТВИЯ ХРОНИЧЕСКОГО СТРЕССА О. В. Николаева, Е. А. Павлова, В. А. Сиренко, М. В. Ковальцова, И. А. Сулхдост Харьковский национальный медицинский университет, Харьков, Украина Проведено морфологическое и биохимическое исследование влияния хронического стресса матери на морфофункциональные особенности поджелудочной железы новорожденного, одномесячного и двухмесячного потомства. Обнаружено, что пренатальный стресс приводит к морфофункциональной перестройке поджелудочной железы крысиного потомства, с развитием стойких и прогрессирующих в динамике деструктивных изменений в ациноцитах и эндокриноцитах, к снижению морфофункциональной активности части клеточных элементов, к развитию гемодинамических нарушений у части животных. Выяснено, что у разновозрастного крысиного потомства наблюдается системный гуморальный ответ в виде дисбаланса цитокинов с преобладанием  маркерного цитокина Th1-лимфоцитов (интерлейкина-12), что свидетельствует о вовлечении в патогенезе повреждения поджелудочной железы клеточной цепи иммунитета. Установлено, что цитокиновый дисбаланс негативно влияет на внутриклеточный метаболизм панкреацитов, их экзокринную и эндокринную секреторную активность, и, вероятно, может еще больше усиливать повреждения поджелудочной железы у экспериментальных животных.          Ключевые слова: ациноциты, эндокриноциты, иммобилизация, интерлейкины, крысята, эксперимент
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