PANDA: A case-study examining a successful Audiology and Otology Patient and Public Involvement and Engagement research group

There has been increasing involvement of patients and members of the public in research; however, case studies describing patient research groups with hearing loss are non-existent. Such case studies will be valuable, enabling evidence-based dialogue and promoting best practice in the engagement of patients, the public and researchers. This paper aims to discuss this practice. The absence of such dialogue may hinder initial efforts by researchers to realise the potential of Patient and Public Involvement. The objective of this study was to set up and run a patient and public involvement and engagement group in audiology research, use the lessons learnt to provide a guide to others in a similar situation, and prompt the dialogue referred to above. A successful group with over 70 members has been set up, with an average attendance for meetings of between 15 and 20 participants. Feedback from the group indicates that members are happy with, and benefit from, their involvement and particularly appreciate the concern of those managing the group better to accommodate sensory impairments. Additionally, the group has improved research output for specific grant applications. We conclude that although this case study contains elements unique to the setting (a large NHS Trust in the Midlands), it also provides transferable observations and resources that can be adapted and utilised by researchers working with patients and the public with hearing loss. Experience Framework This article is associated with the Patient, Family & Community Engagement lens of The Beryl Institute Experience Framework. (http://bit.ly/ExperienceFramework) Access other PXJ articles related to this lens. Access other resources related to this lens

Properties of High-Latitude CME-Driven Disturbances During Ulysses Second Northern Polar Passage

Ulysses observed five coronal mass ejections (CMEs) and their associated disturbances while the spacecraft was immersed in the polar coronal hole (CH) flow above 70° N in late 2001. Of these CMEs, two were very fast (\u3e850 km s−1) driving strong shocks in the wind ahead, and two others were over-expanding. The two fast CMEs were observed leaving the Sun by LASCO/SOHO, and were observed in the ecliptic by Genesis and ACE. These were large events, spanning at least from the northern heliospheric pole to the ecliptic. One-dimensional hydrodynamic simulations indicate that these could be described as overpressured CMEs launched from the Sun at speeds initially faster than ambient, but then decelerating to the ambient solar wind speed as they propagated outward. The two over-expanding CMEs mark their first occurrence since Ulysses’ first orbit when such CMEs were only observed in polar CH flow

Recent Developments of NEMO: Detection of Solar Eruptions Characteristics

The recent developments in space instrumentation for solar observations and telemetry have caused the necessity of advanced pattern recognition tools for the different classes of solar events. The Extreme ultraviolet Imaging Telescope (EIT) of solar corona on-board SOHO spacecraft has uncovered a new class of eruptive events which are often identified as signatures of Coronal Mass Ejection (CME) initiations on solar disk. It is evident that a crucial task is the development of an automatic detection tool of CMEs precursors. The Novel EIT wave Machine Observing (NEMO) (http://sidc.be/nemo) code is an operational tool that detects automatically solar eruptions using EIT image sequences. NEMO applies techniques based on the general statistical properties of the underlying physical mechanisms of eruptive events on the solar disc. In this work, the most recent updates of NEMO code - that have resulted to the increase of the recognition efficiency of solar eruptions linked to CMEs - are presented. These updates provide calculations of the surface of the dimming region, implement novel clustering technique for the dimmings and set new criteria to flag the eruptive dimmings based on their complex characteristics. The efficiency of NEMO has been increased significantly resulting to the extraction of dimmings observed near the solar limb and to the detection of small-scale events as well. As a consequence, the detection efficiency of CMEs precursors and the forecasts of CMEs have been drastically improved. Furthermore, the catalogues of solar eruptive events that can be constructed by NEMO may include larger number of physical parameters associated to the dimming regions.Comment: 12 Pages, 5 figures, submitted to Solar Physic

Evidence of component merging equatorward of the cusp

The Polar spacecraft passed through a region near the dayside magnetopause on May 29, 1996, at a geocentric distance of similar to 8 R-E and high, northern magnetic latitudes. The interplanetary magnetic field (IMF) was northward during the pass. Data from the Thermal Ion Dynamics Experiment revealed the existence of low-speed (similar to 50 km s(-1)) ion D-shaped distributions mixed with cold ions (similar to 2 eV) over a period of 2.5 hours. These ions were traveling parallel to the magnetic field toward the Northern Hemisphere ionosphere and were convecting primarily eastward. The D-shaped distributions are distinct from a convecting Maxwellian and, along with the magnetic field direction, are taken as evidence that the spacecraft was inside the magnetosphere and not in the magnetosheath. Furthermore, the absence of ions in the antiparallel direction is taken as evidence that low-shear merging was occurring at a location southward of the spacecraft and equatorward of the Southern Hemisphere cusp. The cold ions were of ionospheric origin, with initially slow field-aligned speeds, which were accelerated upon reflection from the magnetopause. These observations provide significant new evidence consistent with component magnetic merging sites equatorward of the cusp for northward IMF

Compilation of extended recursion in call-by-value functional languages

This paper formalizes and proves correct a compilation scheme for mutually-recursive definitions in call-by-value functional languages. This scheme supports a wider range of recursive definitions than previous methods. We formalize our technique as a translation scheme to a lambda-calculus featuring in-place update of memory blocks, and prove the translation to be correct.Comment: 62 pages, uses pi

Adaptation to climate change: a comparative analysis of modelling methods for heat-related mortality

Background: Multiple methods are employed for modelling adaptation when projecting the impact of climate change on heat-related mortality. The sensitivity of impacts to each is unknown because they have never been systematically compared. In addition, little is known on the relative sensitivity of impacts to “adaptation uncertainty” (i.e. the inclusion/exclusion of adaptation modelling), relative to using multiple climate models and emissions scenarios. Objectives: (1) Compare the range in projected impacts that arises from using different adaptation modelling methods; (2) compare the range in impacts that arises from adaptation uncertainty to ranges from using multiple climate models and emissions scenarios; (3) recommend modelling method(s) to use in future impact assessments. Methods: We estimated impacts for 2070-2099, for 14 European cities, applying six different methods for modelling adaptation; also with climate projections from five climate models, run under two emissions scenarios to explore the relative effects of climate modelling and emissions uncertainty. Results: The range of the difference (%) in impacts between including and excluding adaptation, irrespective of climate modelling and emissions uncertainty, can be as low as 28% with one method and up to 103% with another (mean across 14 cities). In 13 of 14 cities the ranges in projected impacts due to adaptation uncertainty are larger than those associated with climate modelling and emissions uncertainty. Conclusions: Researchers should carefully consider how to model adaptation because it is a source of uncertainty that can be greater than the uncertainty in emissions and climate modelling. We recommend absolute threshold shifts and reductions in slope

Deflection and Rotation of CMEs from Active Region 11158

Between the 13 and 16 of February 2011 a series of coronal mass ejections (CMEs) erupted from multiple polarity inversion lines within active region 11158. For seven of these CMEs we use the Graduated Cylindrical Shell (GCS) flux rope model to determine the CME trajectory using both Solar Terrestrial Relations Observatory (STEREO) extreme ultraviolet (EUV) and coronagraph images. We then use the Forecasting a CME's Altered Trajectory (ForeCAT) model for nonradial CME dynamics driven by magnetic forces, to simulate the deflection and rotation of the seven CMEs. We find good agreement between the ForeCAT results and the reconstructed CME positions and orientations. The CME deflections range in magnitude between 10 degrees and 30 degrees. All CMEs deflect to the north but we find variations in the direction of the longitudinal deflection. The rotations range between 5\mydeg and 50\mydeg with both clockwise and counterclockwise rotations occurring. Three of the CMEs begin with initial positions within 2 degrees of one another. These three CMEs all deflect primarily northward, with some minor eastward deflection, and rotate counterclockwise. Their final positions and orientations, however, respectively differ by 20 degrees and 30 degrees. This variation in deflection and rotation results from differences in the CME expansion and radial propagation close to the Sun, as well as the CME mass. Ultimately, only one of these seven CMEs yielded discernible in situ signatures near Earth, despite the active region facing near Earth throughout the eruptions. We suggest that the differences in the deflection and rotation of the CMEs can explain whether each CME impacted or missed the Earth.Comment: 18 pages, 6 figures, accepted in Solar Physic

Developing an expanded vector control toolbox for malaria elimination

Vector control using long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) accounts for most of the malaria burden reductions achieved recently in low and middle-income countries (LMICs). LLINs and IRS are highly effective, but are insufficient to eliminate malaria transmission in many settings because of operational constraints, growing resistance to available insecticides and mosquitoes that behaviourally avoid contact with these interventions. However, a number of substantive opportunities now exist for rapidly developing and implementing more diverse, effective and sustainable malaria vector control strategies for LMICs. For example, mosquito control in high-income countries is predominantly achieved with a combination of mosquito-proofed housing and environmental management, supplemented with large-scale insecticide applications to larval habitats and outdoor spaces that kill off vector populations en masse, but all these interventions remain underused in LMICs. Programmatic development and evaluation of decentralised, locally managed systems for delivering these proactive mosquito population abatement practices in LMICs could therefore enable broader scale-up. Furthermore, a diverse range of emerging or repurposed technologies are becoming available for targeting mosquitoes when they enter houses, feed outdoors, attack livestock, feed on sugar or aggregate into mating swarms. Global policy must now be realigned to mobilise the political and financial support necessary to exploit these opportunities over the decade ahead, so that national malaria control and elimination programmes can access a much broader, more effective set of vector control interventions

The future of enterprise groupware applications

This paper provides a review of groupware technology and products. The purpose of this review is to investigate the appropriateness of current groupware technology as the basis for future enterprise systems and evaluate its role in realising, the currently emerging, Virtual Enterprise model for business organisation. It also identifies in which way current technological phenomena will transform groupware technology and will drive the development of the enterprise systems of the future