Modeling of premixing-prevaporizing fuel-air mixing passages

The development of a computer program for the analytical prediction of the distribution of liquid and vapor fuel in the premixing-prevaporizing passage by the direct injection method is described. The technical approach adopted for this program is to separate the problem into three parts each with its own computer code. These three parts are: calculation of the two-dimensional or axisymmetric air flow; calculation of the three-dimensional fuel droplet evaporation; and calculation of the fuel vapor diffusion. This method of approach is justified because premixing passages operate at lean equivalence ratios. Hence, a weak interaction assumption can be made wherein the airflow can affect the fuel droplet behavior but the fuel droplet behavior does not affect the airflow

Analytical modeling of operating characteristics of premixing-prevaporizing fuel-air mixing passages. Volume 2: User's manual

A user's manual describing the operation of three computer codes (ADD code, PTRAK code, and VAPDIF code) is presented. The general features of the computer codes, the input/output formats, run streams, and sample input cases are described

Z' Physics

The limits on extra neutral gauge bosons, which could be reached at LEP2, are reviewed. Exclusion and discovery limits are discussed for f\bar f and WW production.Comment: 20 pages Latex, 7 figures included by epsfig, Contribution to the Proceedings the workshop "Physics at LEP2", Geneva, 199

Extraction of the pion distribution amplitude from polarized muon pair production

We consider the production of muon pairs from the scattering of pions on longitudinally polarized protons. We calculate the cross section and the single spin asymmetry for this process, taking into account pion bound state effects. We work in the kinematic region where the photon has a large longitudinal momentum fraction, which allows us to treat the bound state problem perturbatively. Our predictions are directly proportional to the pion distribution amplitude. A measurement of the polarized Drell-Yan cross section thus allows the determination of the shape of the pion distribution amplitude.Comment: 13 pages, using revtex, two figures added separately as one uuencoded Z-compressed fil

New Physics Potential with a Neutrino Telescope

Active Galactic Nuclei are considered as sources of neutrinos, with neutrino energies extending up to 10^{18} eV. It is expected that these highly energetic cosmic neutrinos will be detected by the neutrino telescopes, presently under construction. The detection process is very sensitive to the total muon neutrino cross-section. We examine how the total cross section changes at high energies, by the single production of excited fermions (excited muon and muon-neutrino). For parameters (masses, couplings) of the excited fermions allowed by the experimental constraints, we find that for energies of the incoming muon-neutrino above 100 TeV the cross-section for single production of (excited muon and muon-neutrino) supersedes the standard total cross-section.Comment: 12 pages and 2 figures; typset using revtex; postscript files for the figures provide

CP-odd observables in neutralino production with transverse e+ and e- beam polarization

We consider neutralino production and decay e^+e^ --> chi^0_i chi^0_j, chi^0_j --> chi^0_1 f \bar{f} at a linear collider with transverse e^+ and e^- beam polarization. We propose CP asymmetries by means of the azimuthal distribution of the produced neutralinos and of that of the final leptons, while taking also into account the subsequent decays of the neutralinos. We include the complete spin correlations between production and decay. Our framework is the Minimal Supersymmetric Standard Model with complex parameters. In a numerical study we show that there are good prospects to observe these CP asymmetries at the International Linear Collider and estimate the accuracy expected for the determination of the phases in the neutralino sector.Comment: 30 pages, minor changes in the introduction, references adde

FRA-1 protein overexpression is a feature of hyperplastic and neoplastic breast disorders

BACKGROUND: Fos-related antigen 1 (FRA-1) is an immediate early gene encoding a member of AP-1 family of transcription factors involved in cell proliferation, differentiation, apoptosis, and other biological processes. fra-1 gene overexpression has an important role in the process of cellular transformation, and our previous studies suggest FRA-1 protein detection as a useful tool for the diagnosis of thyroid neoplasias. Here we investigate the expression of the FRA-1 protein in benign and malignant breast tissues by immunohistochemistry, Western blot, RT-PCR and qPCR analysis, to evaluate its possible help in the diagnosis and prognosis of breast neoplastic diseases. METHODS: We investigate the expression of the FRA-1 protein in 70 breast carcinomas and 30 benign breast diseases by immunohistochemistry, Western blot, RT-PCR and qPCR analysis. RESULTS: FRA-1 protein was present in all of the carcinoma samples with an intense staining in the nucleus. Positive staining was also found in most of fibroadenomas, but in this case the staining was present both in the nucleus and cytoplasm, and the number of positive cells was lower than in carcinomas. Similar results were obtained from the analysis of breast hyperplasias, with no differences in FRA-1 expression level between typical and atypical breast lesions; however the FRA-1 protein localization is mainly nuclear in the atypical hyperplasias. In situ breast carcinomas showed a pattern of FRA-1 protein expression very similar to that observed in atypical hyperplasias. Conversely, no FRA-1 protein was detectable in 6 normal breast tissue samples used as controls. RT-PCR and qPCR analysis confirmed these results. Similar results were obtained analysing FRA-1 expression in fine needle aspiration biopsy (FNAB) samples. CONCLUSION: The data shown here suggest that FRA-1 expression, including its intracellular localization, may be considered a useful marker for hyperplastic and neoplastic proliferative breast disorders

Summary of the SUSY Working Group of the 1999 Les Houches Workshop

The results obtained by the Working Group on Supersymmetry at the 1999 Les Houches Workshop on Collider Physics are summarized. Separate chapters treat "general" supersymmetry, R-parity violation, gauge mediated supersymmetry breaking, and anomaly mediated supersymmetry breaking.Comment: LaTeX, 110 pages with numerous .ps and .eps files. proc.tex is main tex fil

Tests for a Strong Electroweak Sector at Future e^+e^- High Energy Colliders

The study of the scattering at high energy of the gauge bosons W and Z, in particular longitudinally polarized W and Z, can clarify the mechanism of spontaneous symmetry breaking in the Standard Model of the electroweak interactions. Different models of strong electroweak sector, based on the effective lagrangian approach are briefly reviewed. They include models with no resonance, with scalar resonance, additional vector and axial-vector resonances. The effective Lagrangians are derived from the chiral symmetry of the symmetry breaking sector. Limits on these models from existing measurements, mainly LEP and Tevatron, are considered. We study also direct and indirect effects of the new interactions at high energy future e^+e^- linear colliders, through WW scattering and the direct production of these new vector gauge bosons.Comment: 74 pages, 19 figures and 4 tables included, Latex, uses epsf, to appear in La Rivista del Nuovo Cimento, some minor change

The Escherichia coli transcriptome mostly consists of independently regulated modules

Underlying cellular responses is a transcriptional regulatory network (TRN) that modulates gene expression. A useful description of the TRN would decompose the transcriptome into targeted effects of individual transcriptional regulators. Here, we apply unsupervised machine learning to a diverse compendium of over 250 high-quality Escherichia coli RNA-seq datasets to identify 92 statistically independent signals that modulate the expression of specific gene sets. We show that 61 of these transcriptomic signals represent the effects of currently characterized transcriptional regulators. Condition-specific activation of signals is validated by exposure of E. coli to new environmental conditions. The resulting decomposition of the transcriptome provides: a mechanistic, systems-level, network-based explanation of responses to environmental and genetic perturbations; a guide to gene and regulator function discovery; and a basis for characterizing transcriptomic differences in multiple strains. Taken together, our results show that signal summation describes the composition of a model prokaryotic transcriptome