838 research outputs found
The Keck+Magellan Survey for Lyman Limit Absorption II: A Case Study on Metallicity Variations
We present an absorption line analysis of the Lyman limit system (LLS) at
z=3.55 in our Magellan/MIKE spectrum of PKS2000-330. Our analysis of the Lyman
limit and full HI Lyman series constrains the total HI column density of the
LLS (N_HI = 10^[18.0 +/- 0.25] cm^{-2} for b_HI >= 20 km/s) and also the N_HI
values of the velocity subsystems comprising the absorber. We measure ionic
column densities for metal-line transitions associated with the subsystems and
use these values to constrain the ionization state (>90% ionized) and relative
abundances of the gas. We find an order of magnitude dispersion in the
metallicities of the subsystems, marking the first detailed analysis of
metallicity variations in an optically thick absorber. The results indicate
that metals are not well mixed within the gas surrounding high galaxies.
Assuming a single-phase photoionization model, we also derive an N_H-weighted
metallicity, = -1.66 +/- 0.25, which matches the mean metallicity in
the neutral ISM in high z damped Lya systems (DLAs). Because the line density
of LLSs is ~10 times higher than the DLAs, we propose that the former dominate
the metal mass-density at z~3 and that these metals reside in the galaxy/IGM
interface. Considerations of a multi-phase model do not qualitatively change
these conclusions. Finally, we comment on an anomalously large O^0/Si^+ ratio
in the LLS that suggests an ionizing radiation field dominated by soft UV
sources (e.g. a starburst galaxy). Additional abundance analysis is performed
on the super-LLS systems at z=3.19.Comment: 20 pages, 7 figures (most in color). Accepted to Ap
Prevalence, heterogeneity of asymptomatic malaria infections and associated factors in a high transmission region
Background: Although current reports have shown a reduction in malaria cases, the disease still remains a major public health problem in Kenya. In most endemic regions, the majority of infections are asymptomatic which means those infected may not even know and yet they remain infectious to the mosquitoes. Asymptomatic infections are a major threat to malaria control programs since they act as silent reservoirs for the malaria parasites.Objective: The study sought to determine the prevalence of asymptomatic malaria infections, whether they show heterogeneity spatially, across age groups and across time as well as their determinants in a high transmission region.Study Design: This was part of a larger prospective cohort study on malaria indices in the HDSS.Study Setting: The study was conducted in the Webuye Health and Demographic Surveillance Site in Bungoma East Sub-County.Study Subjects: Quarterly parasitological surveys were conducted for a cohort of 400 participants from randomly selected households located in known fever “hotspots” and “coldspots”. Follow-up of all the participants continued for a period of one year. Generalized estimating equations were used to model risk factors associated with asymptomatic parasitemia.Results: Of the total 321 malaria infections detected during the five cross-sectional surveys conducted over the period of one year, almost half (46.3%) of these were asymptomatic. Overall, most of the asymptomatic cases (67%) were in households within known fever “hotspots”. The proportion of infections that were asymptomatic in the coldspots were 73.1%, 31.8%, 13.3%, 55.6% and 48.2% during the first, second, third, fourth and fifth visits respectively. In the known fever “hotspots”, the proportion of infections without symptoms was 47.7%, 48.5%, 35%, 41.3% and 47.5% during the first, second, third, fourth and fifth visits respectively. Factors associated with asymptomatic malaria include; the village one lives: people living in village M were twice likely to be asymptomatic (A.O.R: 2.141, C.I: 0.03 - 1.488), age: children aged between 6 to 15 years were more than twice likely to be asymptomatic (A.O.R: 2.67, C.I. 0.434 - 1.533) and the season: infections during the dry season (January) were less likely to be asymptomatic (A.O.R: 0.26, C.I: -2.289 - 0.400).Conclusion: The prevalence of asymptomatic infections in this region is still very high. The highest proportion of asymptomatic infections was registered in a fever coldpspot village which may explain why the village is a fever coldspot in the first place. There is a need for active surveillance to detect the asymptomatic cases as well as treat them in-order to reduce the reservoir. Targeting interventions to the asymptomatic individuals will further reduce the transmission within this region
Malaria “hotspots” within a larger hotspot; what’s the role of behavioural factors in fine scale heterogeneity in western Kenya?
Background: Malaria remains a major public health problem in Kenya accounting for the highest morbidity and mortality especially among children. Previous reports indicate that infectious agents display heterogeneity in both space and time and malaria is no exception. Heterogeneity has been shown to reduce the effectiveness of interventions. Previous studies have implicated genetic (both human and parasite) and environmental factors as mainly responsible for variation in malaria risk. Human behaviour and its potential risk for contributing to variation in malaria risk has not been extensively explored.Objective: To determine if there were behavioural differences between the people living in hotspots (high malaria burden) and cold spots (low malaria burden) within a geographically homogeneous and high malaria transmission region.Design: A prospective closed cohort study.Setting: The study was conducted in the Health and Demographic Surveillance Site in Bungoma East sub-County.Subjects: A total of 400 people in randomly selected households in both the fever hotspots and cold spots were tested for malaria at quarterly intervals using malaria rapid diagnostic tests (RDTs).Results: Significant heterogeneity in malaria incidence and prevalence was observed between villages. Incidence of malaria was significantly higher in the hotspots (high malaria burden areas) compared to the cold spots (low malaria burden) (49 episodes per 1000 person months compared to 26/1000, t test p < 0.001). The incidence also varied significantly among the individual villages by season (P: 0.0071). Knowledge on malaria therapy was significantly associated with whether one was in the cold spot or hotspot (P: 0.033). Behavioural practices relating to ITN use were significantly associated with region during particular seasons (P: 0.0001 and P: 0.0001 respectively).Conclusion: There is marked and significant variation in the incidence of malaria among the villages creating actual hotspots of malaria within the larger hotspot. There is a significant difference in malaria infections between the hotspots and cold spots. Knowledge on malaria therapy and behavioural factors such as ITN use may contribute to the observed differences during some seasons
Archeops: an instrument for present and future cosmology
Archeops is a balloon-borne instrument dedicated to measure the cosmic
microwave background (CMB) temperature anisotropies. It has, in the millimetre
domain (from 143 to 545 GHz), a high angular resolution (about 10 arcminutes)
in order to constrain high l multipoles, as well as a large sky coverage
fraction (30%) in order to minimize the cosmic variance. It has linked, before
WMAP, Cobe large angular scales to the first acoustic peak region. From its
results, inflation motivated cosmologies are reinforced with a flat Universe
(Omega_tot=1 within 3%). The dark energy density and the baryonic density are
in very good agreement with other independent estimations based on supernovae
measurements and big bang nucleosynthesis. Important results on galactic dust
emission polarization and their implications for Planck are also addressed.Comment: 4 pages, 2 figures, to appear in Proceedings of the Multiwavelength
Cosmology Conference, June 2003, Mykonos Island, Greec
On the galloping instability of two-dimensional bodies having elliptical cross sections.
Galloping, also known as Den Hartog instability, is the large amplitude, low frequency oscillation of a structure in the direction transverse to the mean wind direction. It normally appears in the case of bodies with small stiffness and structural damping, when they are placed in a flow provided the incident velocity is high enough. Galloping depends on the slope of the lift coefficient versus angle of attack curve, which must be negative. Generally speaking this implies that the body is stalled after boundary layer separation, which, as it is known in non-wedged bodies, is a Reynolds number dependent phenomenon. Wind tunnel experiments have been conducted aiming at establishing the characteristics of the galloping motion of elliptical cross-section bodies when subjected to a uniform flow, the angles of attack ranging from 0° to 90°. The results have been summarized in stability maps, both in the angle of attack versus relative thickness and in the angle of attack versus Reynolds number planes, where galloping instability regions are identified
The Deuterium to Hydrogen Abundance Ratio Towards a Fourth QSO: HS0105+1619
We report the measurement of the primordial D/H abundance ratio towards QSO
\object. The column density of the hydrogen in the Lyman limit
system is high, \lnhi \cmm, allowing for the deuterium to
be seen in 5 Lyman series transitions. The measured value of the D/H ratio
towards QSO \object is found to be D/H. The
metallicity of the system showing D/H is found to be solar,
indicating that the measured D/H is the primordial D/H within the measurement
errors. The gas which shows D/H is neutral, unlike previous D/H systems which
were more highly ionized. Thus, the determination of the D/H ratio becomes more
secure since we are measuring it in different astrophysical environments, but
the error is larger because we now see more dispersion between measurements.
Combined with prior measurements of D/H, the best D/H ratio is now D/H, which is 10% lower than the previous value. The new
values for the baryon to photon ratio, and baryonic matter density derived from
D/H are and \ob
respectively.Comment: Minor text and reference changes. To appear in the May 10, 2001 issue
of the Astrophysical Journa
Constraining The Universal Lepton Asymmetry
The relic cosmic background neutrinos accompanying the cosmic microwave
background (CMB) photons may hide a universal lepton asymmetry orders of
magnitude larger than the universal baryon asymmetry. At present, the only
direct way to probe such an asymmetry is through its effect on the abundances
of the light elements produced during primordial nucleosynthesis. The relic
light element abundances also depend on the baryon asymmetry, parameterized by
the baryon density parameter (eta_B = n_B/n_gamma = 10^(-10)*eta_10), and on
the early-universe expansion rate, parameterized by the expansion rate factor
(S = H'/H) or, equivalently by the effective number of neutrinos (N_nu = 3 +
43(S^2 - 1)/7). We use data from the CMB (and Large Scale Structure: LSS) along
with the observationally-inferred relic abundances of deuterium and helium-4 to
provide new bounds on the universal lepton asymmetry, finding for eta_L, the
analog of eta_B, 0.072 +/- 0.053 if it is assumed that N_nu = 3 and, 0.115 +/-
0.095 along with N_nu = 3.3^{+0.7}_{-0.6}, if N_nu is free to vary
Gas Accretion via Lyman Limit Systems
In cosmological simulations, a large fraction of the partial Lyman limit
systems (pLLSs; 16<log N(HI)<17.2) and LLSs (17.2log N(HI)<19) probes
large-scale flows in and out of galaxies through their circumgalactic medium
(CGM). The overall low metallicity of the cold gaseous streams feeding galaxies
seen in these simulations is the key to differentiating them from metal rich
gas that is either outflowing or being recycled. In recent years, several
groups have empirically determined an entirely new wealth of information on the
pLLSs and LLSs over a wide range of redshifts. A major focus of the recent
research has been to empirically determine the metallicity distribution of the
gas probed by pLLSs and LLSs in sizable and representative samples at both low
(z2) redshifts. Here I discuss unambiguous evidence for
metal-poor gas at all z probed by the pLLSs and LLSs. At z<1, all the pLLSs and
LLSs so far studied are located in the CGM of galaxies with projected distances
<100-200 kpc. Regardless of the exact origin of the low-metallicity pLLSs/LLSs,
there is a significant mass of cool, dense, low-metallicity gas in the CGM that
may be available as fuel for continuing star formation in galaxies over cosmic
time. As such, the metal-poor pLLSs and LLSs are currently among the best
observational evidence of cold, metal-poor gas accretion onto galaxies.Comment: Invited review to appear in Gas Accretion onto Galaxies, Astrophysics
and Space Science Library, eds. A. J. Fox & R. Dav\'e, to be published by
Springe
Constraints on the Universal CIV Mass Density at z~6 from Early IR Spectra Obtained with the Magellan FIRE Spectrograph
We present a new determination of the intergalactic CIV mass density at 4.3 <
z < 6.3. Our constraints are derived from high signal-to-noise spectra of seven
quasars at z > 5.8 obtained with the newly commissioned FIRE spectrograph on
the Magellan Baade telescope, coupled with six observations of northern objects
taken from the literature. We confirm the presence of a downturn in the CIV
abundance at =5.66 by a factor of 4.1 relative to its value at =4.96, as
measured in the same sightlines. In the FIRE sample, a strong system previously
reported in the literature as CIV at z=5.82 is re-identified as MgII at z=2.78,
leading to a substantial downward revision in for these prior
studies. Additionally we confirm the presence of at least two systems with
low-ionization CII, SiII, and OI absorption but relatively weak signal from
CIV. The latter systems systems may be of interest if the downward trend in
at high redshift is driven in part by ionization effects.Comment: 14 pages, 6 figures, 2 tables. Submitted to Ap
Early-universe constraints on a time-varying fine structure constant
Higher-dimensional theories have the remarkable feature of predicting a time
(and hence redshift) dependence of the `fundamental' four dimensional constants
on cosmological timescales. In this paper we update the bounds on a possible
variation of the fine structure constant alpha at the time of BBN (z =10^10)
and CMB (z=10^3). Using the recently-released high-resolution CMB anisotropy
data and the latest estimates of primordial abundances of 4He and D, we do not
find evidence for a varying alpha at more than one-sigma level at either epoch.Comment: 5 pages, 1 figure, minor misprints corrected, references added. The
analysis has been updated using new BOOMERanG and DASI data on CMB anisotrop
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