Relationship Between Heart Rate Recovery and Mean Platelet Volume in Healthy Individuals

Heart rate recovery index (HRRI) and mean platelet volume (MPV) are two cardiovascular prognostic markers. Low HRRI and high MPV values have been observed in several diseases and conditions. However, the relationship between these two markers is unclear. In this study, the relationship between HRRI and MPV in healthy individuals is examined. Materials and Methods: The exercise tests performed between January and December 2020 were evaluated, and 120 individuals who met the study criteria were included in the present study. An abnormal HRRI was defined as a decrease in heart rate of 12 beats or more until one minute after the peak of exercise. Those with abnormal HRRI were defined as the study group (n=60), and those with normal HRRI as the control group (n=60). Results: A total of 120 healthy individuals were included in the study (54% female; mean age 40.14±7.90 years). High- er MPV values were detected in the study group when compared to the control group (10.27±0.10 fl vs. 9.44±0.12 fl; p<0.001). This significance continued in the logistic regression analysis (odds ratio=3.78, p<0.001). In addition, a moderate negative correlation was found between HRRI and MPV (r=-0.404, p<0.001). The MPV value of 10.25 fl was identified as an effective cutoff point for the prediction of abnormal HRRI (area under the curve [AUC]: 0.758; 95% confidence interval [CI]: 0.674–0.843). Conclusion: Healthy individuals with abnormal HRRI have elevated MPV levels. Additionally, a negative correlation be- tween MPV and HRRI in healthy subjects indicates a causal relation between MPV and autonomic dysfunction

A case with late clinical presentation of Takayasu’s arteritis

Takayasu's arteritis also known as pulseless disease is a kind of granulomatous vasculitis that characterized large size vessels involvement with massive intimal fibrosis. It is usually occurs in female gender in middle ages. Unusual Takayasu's arteritis case with different clinical presentation was reported in current paper. A 42 years old male patient was admitted to cardiovascular surgery clinic with sudden onset cyanosis in first finger of right hand. There was not any finding or complaint in his past medical history. The right brachial, radial and ulnar pulses were not palpable in physical examination and blood pressure could not measured from this extremity. Bilateral upper limb arterial doppler ultrasound revealed minimal flow in right and disrupted biphasic flow pattern in left. Peripheral angiography revealed total occlusion after the osteal segment of right subclavian artery, pre-occlusive stenosis in proximal segment of left subclavian artery and total occlusion in abdominal aorta just prior the iliac bifurcation. There was no serological or biochemical positivity in blood parameters and no additional visualization finding. Antiaggregant, anticoagulant and intravenous peripheral vasodilator therapy was utilized to patient for finger cyanosis. Patient was discharged with full recovery of finger coloration and referred to rheumatology clinic for further investigation. Microembolism may be messenger of wide-spread vascular disorders for example vasculitis. Thus, detailed systemic examinations should be applied in patients who admitted with micro-circulatory system symptoms

Design and implementation of battery management system based on passive balancing method for electric vehicles using STM32f103C8 microcontroller

Önerilen çalışmada elektrikli araçlarda kullanılmak üzere dört hücreli batarya paketi için pasif hücre dengeleme metodu tabanlı batarya yönetim sistemi tasarlanmış ve uygulaması gerçekleştirilmiştir. Batarya yönetim sisteminin yazılımsal ve donanımsal altyapısı Master-Slave mantığına göre oluşturulmuştur. Bu nedenle üç hücre verileri okuyup master hücreye göndermektedir. Master hücre, kendi hücresinin ve slave hücrelerden gelen verileri okur. Gelen verilere göre de batarya hücrelerinin gerilim dengeleme işlemlerinin kontrolünü ve yönetimini gerçekleştirir. Hücreler kendi içerisinde CAN protokolü ile haberleşmektedir. Her bir hücreden akım, gerilim ve sıcaklık verileri okunarak hücrelerin şarj işlemi kontrollü bir şekilde gerçekleştirilebilmektedir. Batarya yönetim sisteminde direnç tabanlı pasif kontrol yöntemi kullanılmıştır. Pasif balanslama (dengeleme) yönteminde direnç yerine P kanallı metal oksit yarı iletken anahtarlama elemanı kullanılarak gerilim dengeleme işlemi gerçekleştirilmiştir. Ayrıca özgün bir dijital analog dönüştürme devresi tasarlanarak pasif hücre dengeleme tabanlı batarya yönetim sisteminde uygulanmıştır. Batarya yönetim sisteminin uygulaması ve şarj işlemi başarılı bir şekilde gerçekleştirilmiştir. Tasarlanan batarya yönetim sisteminin başarılı bir şekilde çalıştığı elde edilen deneysel sonuçlar aracılığı ile kanıtlanmıştır.In the proposed study, a battery management system based on passive cell balancing method was designed and implemented for the four cell battery pack to be used in electric vehicles. The software and hardware infrastructure of the battery management system was created according to the MasterSlave logic. For this reason, three cells read the data and send it to the master cell. The master cell reads data from its own cell and slave cells. According to the incoming data, it performs the control and management of the voltage balancing processes of the battery cells. Cells communicate with CAN protocol in themselves. The charging process of the cells can be carried out in a controlled manner by reading current, voltage and temperature data from each cell. Resistance based passive control method is used in the battery management system. In the passive balancing method, voltage balancing is performed by using P channel metal oxide semiconductor switching element instead of resistance. In addition, a unique digital analog conversion circuit was designed and implemented in the passive cell balancing based battery management system. Application and charging of the battery management system has been successfully completed. The designed battery management system has been proven to work successfully through the experimental results obtained

CAN Communication Protocol Based Data Collection System Application using STM32f103C8 microprocessor

Haberleşme, veri toplama ve kontrol işlemleri günümüzün üzerinde çalışılan en önemli alanların başında gelmektedir. Elektronik tabanlı ve endüstriyel sistemlerde veri toplama işlemi oldukça önemlidir. Çünkü yapılacak olan işlemler bu verilere göre şekillenmektedir. Aynı zamanda verilerin doğru bir şekilde okunup ve doğru verinin kontrol sistemine gönderilmesi oldukça önem arz etmektedir. Haberleşme protokolleri içerisinde güvenlik ve verinin alıcıya doğru iletilmesi açısından CAN protokolü en güvenilir haberleşme protokollerinden biridir. Bu çalışmada da CAN haberleşme protokolü tabanlı bir veri toplama sistemi oluşturulmuştur. Isı Ölçüm Devresi, Mesafe Ölçüm Devresi, Işık Şiddeti Ölçüm Devresi ve DC Motor RPM Değeri Ölçüm Devresi birimleri oluşturularak dört farklı sistem oluşturulmuştur. Bu birimlerden elde edilen veriler STM32F103C8T6 işlemcisine CAN protokolü üzerinden aktarılmıştır. Toplanan veriler bu işlemci üzerinden bilgisayar ortamına gönderilmektedir. Tasarlanan arayüz programı ile veriler takip edilebilmekte ve kaydedilebilmektedir. Gerçekleştirilen bu sistem ile aktif olarak çalışan CAN protokolü tabanlı bir veri toplama sistemi oluşturulmuştur. Dört farklı noktadan alınan veriler doğru bir şekilde okunarak kaydetme işlemi gerçekleştirilmiştir.Today, communication, data collection and control processes are among the most important areas studied. Data collection is very important in electronic based and industrial systems. Because the processes to be carried out are shaped according to the incoming data. At the same time, it is very important to read the data correctly and send the correct data to the control system. The CAN protocol is one of the most reliable communication protocols in terms of security and data transmission to the receiver within the communication protocols. In this study, a data collection system based on CAN communication protocol has been established. Four different systems were created by creating units of Temperature Measurement Circuit, Distance Measurement Circuit, Light Intensity Measurement Circuit and DC Motor RPM Value Measurement Circuit. The data obtained from these units were transferred to the STM32F103C8T6 processor via CAN protocol. The collected data is sent to the computer environment via this processor. Data can be tracked and recorded with the designed interface program. A data collection system based on CAN protocol has been created that works actively with this system. The data obtained from four different points were read correctly and the saving was performed

The Use of Total Artificial Heart With Example of Cases for End-Stage Heart Failure Therapy

29th Turkish Cardiology Congress of the Turkish-Society-of-Cardiology (TSC) with International Participation -- OCT 26-29, 2013 -- Antalya, TURKEYWOS: 000329858400098Turkish Soc Cardio

DsPic33fj32mc204 microprocessor based hall sensor brushless direct current motor driver design and proteus simulation application

Bu çalışmada Hall sensörlü fırçasız doğru akım motorlarda kullanılabilecek, dsPic33fj32mc204 tabanlı bir motor sürücü sistemi tasarlanmış ve simülasyon ortamında gerçekleştirilmiştir. Gerçekleştirilen sürücü devresinde, IR2112 tip sürücü entegreleri kullanılarak üç fazlı sürücü devresinde bulunan MOSFET’lerin anahtarlamaları gerçekleştirilmiştir. Proteus programı kullanılarak, tasarlanan fırçasız doğru akım motor sürücü devresinin simülasyonu başarılı bir şekilde yapılmıştır. Motor kontrol sürücü sistemi, piyasada rahat bir şekilde bulunabilecek tipte devre elemanları ile oluşturulmuştur. Bu sayede sürücü devresi kolaylıkla ve ekonomik olarak uygulanabilme özelliklerine sahiptir. Gerçekleştirilen simülasyon uygulaması sayesinde farklı sürücü sistemlerinin geliştirilmesine imkân sağlayacak olan DsPic mikrodenetleyici tabanlı bir sürücü sistemi oluşturulmuştur. Üç fazlı fırçasız doğru akım motorunun kontrol sinyalleri başarılı bir şekilde elde edilmiştir. Sürücü sisteminden elde edilen çıkış sinyalleri ayrıntılı bir şekilde yorumlanmıştır.In this study, a dsPic33fj32mc204 based motor drive system, which can be used in brushless DC motors with Hall sensors, was designed and implemented in a simulation environment. In the driver circuit realized, switching of the MOSFETs in the three-phase driver circuit was performed using IR2112 type driver circuits. Simulation of the designed brushless direct current motor driver circuit has been successfully performed using the Proteus program. The motor control driver system is created with circuit elements of a type that can be conveniently found on the market. In this way, the driver circuit has the features to be applied easily and economically. A DsPic microcontroller based driver system has been created which will allow the development of different drive systems thanks to the simulation application. The control signals of the three-phase brushless direct current motor have been successfully obtained. Output signals from the drive system are interpreted in detail

Diagnostic Value of the Video Head Impulse Test in Patients with Vertigo: Can It Be Used as a Screening Tool?

Background and Aim: Several laboratory tools are used to evaluate balance disorders but, there is still no screening test to determine the site and the severity of the lesion. The aim was to investigate whether video Head Impulse Test (vHIT) can be used as a screening test in patients with chronic or recurrent vertigo and dizziness. Methods: The files of 965 patients who were followed up in our vertigo outpatient clinic were reviewed retrospectively. Vestibulo-Ocular Reflex (VOR) gains and saccadic movements of the right and left lateral canals in the vHIT test, and Canal Paresis (CP) in the Caloric Testing (CT) were noted. Results: A total of 325 patients were included in our study. In CT results, the group that CP was most frequently detected was Menière’s Disease (MD) group (71 patients (74.7%). While vHIT results were found to be pathological in the vast majority of patients in the Vestibular Neuritis (VN) group (72.7%), the results were found to be normal at the highest rate in the vestibular migraine group (77.9%). Correlation analysis showed a significant but weak correlation between the degree of CP in the CT and the VOR gains of the lateral canals in vHIT in all groups. Conclusion: Although it has high sensitivity in cases with VN and vestibulopathy, we think that vHIT cannot be used as a screening tool in patients with vertigo, especially for chronic cases, since its sensitivity rate differs in the long term according to the cause of the disease

Long-term obstetric, perinatal, and surgical complications in singleton pregnancies following previous cesarean myomectomy: a retrospective multicentric study

ObjectivesThe safety of cesarean myomectomy has been proven by previous studies. Our study aimed to reveal the long-term perinatal, obstetric, and surgical outcomes of cesarean myomectomy (CM) by comparing different CM techniques.Material and methodsThis retrospective multicentric case–control study involved 7 hospitals and included 226 singleton pregnancies that underwent repeated cesarean section (CS) between 2015 and 2020. Among these pregnancies, 113 of 226 cases had CM (Group A), and 113 had only CS (Group B). Of the 113 cases in which CM was performed, 58 underwent endometrial myomectomy (EM) (Subgroup A1) and 55 underwent serosal myomectomy (SM) (Subgroup A2). The groups were compared in terms of obstetric, perinatal, and surgical outcomes, and fibroid recurrence, myomectomy scar healing rate, and adhesion formation were noted.ResultsThere was no significant difference between the groups in terms of maternal age, body mass index, gravidity, parity, and fibroid diameter in previous CS (p &gt; 0.05). In the perinatal and obstetric evaluation of the groups, there was no significant difference between the groups in terms of neonatal weight, Apgar score, fetal growth restriction, preterm premature rupture of membranes, preterm delivery, hypertension in pregnancy, and diabetes mellitus (p &gt; 0.05). The fibroid recurrence rate was 28.3%, and the myomectomy scar good healing rate was 99.1%. There was no difference between the groups in terms of CS duration, preoperative and postoperative hemoglobin levels, perioperative blood transfusion rates, febrile morbidity, and prolonged hospitalization (p &gt; 0.05). In terms of adhesion formation, although the adhesion rate of the SM group was higher than that of the EM group, no statistically significant difference was detected between the groups.ConclusionThis study showed that in pregnancies following CM, obstetrical, perinatal, and surgical outcomes were unaffected. Obstetricians can safely use CM, either the trans-endometrial or serosal technique, as it is a safe and effective method with long-term results

An oppositional Salp Swarm: Jaya algorithm for thermal design optimization of an Organic Rankine Cycle

This study proposes a hybrid metaheuristic algorithm to tackle both single and multi objective optimization problems that are subjected to hard constraints.Twenty-four single objective optimization benchmark problems comprising unimodal and multi modal test functions have been solved by the proposed hybrid algorithm (OPSSAJ) and numerical results have been compared with those acquired by some of the new emerged metaheuristic optimizers. The proposed OPSSAJ shows a significant accuracy and robustness in most of the cases and proves its efficiency in solving high dimensional problems. As a real-world case study, seventeen operational design parameters of an organic rankine cycle (ORC) operating with a binary mixture of R227EA and R600 refrigerants are optimized by the proposed hybrid OPSSAJ to obtain the optimum values of contradicting dual objectives of second law efficiency and Specific Investment Cost. A Pa reto curve composed of non-dominated solutions is constructed through the weighted sum method and the final solution is chosen by the reputed TOPSIS decision-maker. The pareto curve and best-compromising result obtained by utilizing the OPPSAJ are compared with that of acquired by using nondominated sorting genetic algorithm II (NSGA-II) and multiple objective particle swarm optimization (MOPSO) algorithms. The multi-objective ORC design obtained with the OPSSAJ yields a significant improvement in thermal efficiency and cost values compared to designs found by the NSGA-II and MOPSO algorithms. Furthermore, a sensitivity analysis is performed to observe the influences of the selected design variables on problem objectives

Eagle strategy based on modified barnacles mating optimization and differential evolution algorithms for solving transient heat conduction problems

Solving time-dependent heat conduction problems through a conventional solution procedure of iterative root-finding method may sometimes cause difficulties in obtaining accurate temperature distribution across the heat transfer medium. Analytical root-finding methods require good initial estimates for finding exact solutions, however locating these promising regions is some kind of a black-box process. One possible answer to this problem is to convert the root-finding equation into an optimization problem, which eliminates the exhaustive process of determining the correct initial guess. This study proposes an Eagle Strategy optimization framework based on modified mutation equations of Barnacles Mating Optimizer and Differential Evolution algorithm for solving one-dimensional transient heat conduction problems. A test suite of forty optimization benchmark problems have been solved by the proposed algorithm and the respective solution outcomes have been compared with those found by the reputed literature optimizers. Finally, a case study associated with a transient heat conduction problem have been solved. Results show that Eagle strategy can provide efficient and feasible results for various types of solution domains. © 2021, Ismail Saritas. All rights reserved