The efficacy of cinacalcet in the treatment of hyperparathyroidism in Turkish hemodialysis patient population

WOS: 000393291900012OBJECTIVE: Cinacalcet reduces parathyroid hormone levels by increasing the sensitivity of the parathyroid gland to calcium. in this study, we firstly aimed to evaluate the efficacy of cinacalcet in Turkish hemodialysis patients. MATERIAL and METHODS: 4483 hemodialysis patients were screened and 469 patients who had used cinacalcet were included in the study. the patients were divided into 4 groups according to drug usage durations (Group 1: 3 months, Group 2: 6 months, Group 3: 9 months and Group 4: 12 months). the patients' Parathormone, Ca, P and CaxP levels at the 3rd, 6th, 9th and 12th months were compared to the start of treatment and previous months. RESULTS: the levels of Parathormone, Ca, P and CaxP significantly decreased compared to their initial levels in all groups (from 1412 pg/ml to 1222 pg/mL for Parathormone, p< 0,001) in the 3rd month. However, this reduction was not continued in the subsequent months (Parathormone: 1381 pg/ml for the 12th month). CONCLUSION: Cinacalcet may not provide adequate benefit in control of hyperparathyroidism in Turkish hemodialysis patient population

Hedef sinyal çıkarımı için doğrusal olmayan uyarlamalı bir hüzme şekillendirme algoritmasının performansı.

In this thesis a non-linear adaptive beamforming technique, Adaptive Projections Subgradient Method [1] (APSM) is considered. This method uses projections over convex sets in Reproducing Kernel Hilbert Space. Main advantage of this method is observed if the signal-of-interest is due to digital modulation and when there are more jammers than the number of antennas. The performance of this non-linear beamforming technique is compared with well-known methods including Minimum Variance Distortionless Response [2] (MVDR) Beamformer, Robust Capon Beamformer [3] (RCB), Covariance Matrix Reconstruction [4] (CMR) Beamformer and Recursive Least Squares [5] (RLS) Capon Beamformer. A new beamformer is proposed in order to fill the gap between the non-linear and classical beamformer methods. It is shown that this new beamformer performs better than well-known methods when the number of jammers are larger than the number of antennas like APSM. However, the computational complexity of this method is significantly lower than APSM. The beamformer methods are compared in a variety of scenario in order to outline the advantages and disadvantages clearly.M.S. - Master of Scienc

Nefron ve Glomerul üç boyutlu yapısının plastik enjeksiyon ve korrozyon yöntemi ile ortaya konulması

TEZ580Tez (Yüksek Lisans) -- Çukurova Üniversitesi, Adana, 1988.Kaynakça (s. 42-44) var.44 s. : rnk. res. ; 30 cm.