A Herpetofaunal Survey of the Braidwood Dunes and Savanna Nature Preserve

A herpetofaunal survey was conducted on two sand prairie areas in Will Co., IL.; The Braidwood Dunes and Savanna Nature Preserve (BD+S), and Sandridge Savanna. Drift fences with pitfall traps, herpetological attractor panels, aquatic hoop traps, and manual collecting were used to sample the two preserves. A species list was compiled, and the habitat preferences and relative abundance of each species present were determined. The species list was compared with the species lists of other Illinois sand areas and the Nebraska sandhills. Guilds represented by the herpetofaunae of each area were also compared. Seventeen species were recorded at BD+S and five were recorded at Sandridge. Based on this and previous studies, a total of 20 reptile and amphibian species are believed to exist at BD+S. The herpetofaunal composition of BD+S and Sandridge was found to be similar to that of the Nebraska sandhills and even more similar to that of other sand areas in Mason Co., IL., while being least like the herpetofaunal composition of the non-sand areas of Will Co. Because of the sand-specific nature of many of the reptiles and amphibians present at BD+S and Sandridge, these areas, and others like them, are important in maintaining populations of such species in the county and the State

A Herpetofaunal Survey of the Braidwood Dunes and Savanna Nature Preserve

A herpetofaunal survey was conducted on two sand prairie areas in Will Co., IL.; The Braidwood Dunes and Savanna Nature Preserve (BD+S), and Sandridge Savanna. Drift fences with pitfall traps, herpetological attractor panels, aquatic hoop traps, and manual collecting were used to sample the two preserves. A species list was compiled, and the habitat preferences and relative abundance of each species present were determined. The species list was compared with the species lists of other Illinois sand areas and the Nebraska sandhills. Guilds represented by the herpetofaunae of each area were also compared. Seventeen species were recorded at BD+S and five were recorded at Sandridge. Based on this and previous studies, a total of 20 reptile and amphibian species are believed to exist at BD+S. The herpetofaunal composition of BD+S and Sandridge was found to be similar to that of the Nebraska sandhills and even more similar to that of other sand areas in Mason Co., IL., while being least like the herpetofaunal composition of the non-sand areas of Will Co. Because of the sand-specific nature of many of the reptiles and amphibians present at BD+S and Sandridge, these areas, and others like them, are important in maintaining populations of such species in the county and the State

Desisting from Prescription Drug Abuse: An Application of Growth Models to Rx Opioid Users

Modern desistance research has examined many facets of desistance, in terms of theoretical predictors of desistance and recidivism, and in terms of differing types of offending. Though predicting desistance from illegal drug use is among these topics, no research to date has examined the predictors of desisting from prescription opioid abuse. This study uses longitudinal data from 318 prescription opioid users to analyze the effects of various predictors of desistance on declining nonmedical prescription opioid use, with an emphasis on gender differences among participants. Results indicate that theoretical and demographic characteristics correspond with differing rates of decline and further vary by gender

33rd New England Intercollegiate Geological Conference: October 8, 9 and 10, 1937, New York City

Excursion A-2: A Geological Traverse from the Hudson River to Long Island Sound; Excursion B-3: Paleontological Trip to the New Jersey Coastal Plain; Excursion C-1: Progressive Metamorphism of the Hudson River Series; Excursion C-2: Glacial Geology of Long Island; Excursion C-3: Engineering Projects in New York City

The Future of American Sentencing: A National Roundtable on Blakely

In the wake of the dramatic Supreme Court decision in Blakely v. Washington, Stanford Law School convened an assembly of the most eminent academic and professional sentencing experts in the country to jointly assess the meaning of the decision and its implications for federal and state sentencing reform. The event took place on October 8 and 9, just a few months after Blakely came down and the very week that the Supreme Court heard the arguments in United States v. Booker and United States v. Fanfan, the cases that will test Blakely\u27s application to the Federal Sentencing Guidelines. Thus the Roundtable offered these experts an intellectual breathing space at a crucial point in American criminal law. The event was built around six sessions, with shifting panels of participants doing brief presentations on the subject of the session, and with others then joining in the discussion. We are pleased that FSR is able to publish this version of the proceedings of the event-a condensed and edited transcript of the sessions

A Framework For Detecting Noncoding Rare-Variant associations of Large-Scale Whole-Genome Sequencing Studies

Large-scale whole-genome sequencing studies have enabled analysis of noncoding rare-variant (RV) associations with complex human diseases and traits. Variant-set analysis is a powerful approach to study RV association. However, existing methods have limited ability in analyzing the noncoding genome. We propose a computationally efficient and robust noncoding RV association detection framework, STAARpipeline, to automatically annotate a whole-genome sequencing study and perform flexible noncoding RV association analysis, including gene-centric analysis and fixed window-based and dynamic window-based non-gene-centric analysis by incorporating variant functional annotations. In gene-centric analysis, STAARpipeline uses STAAR to group noncoding variants based on functional categories of genes and incorporate multiple functional annotations. In non-gene-centric analysis, STAARpipeline uses SCANG-STAAR to incorporate dynamic window sizes and multiple functional annotations. We apply STAARpipeline to identify noncoding RV sets associated with four lipid traits in 21,015 discovery samples from the Trans-Omics for Precision Medicine (TOPMed) program and replicate several of them in an additional 9,123 toPMed samples. We also analyze five non-lipid toPMed traits

Evidence that toxin resistance in poison birds and frogs is not rooted in sodium channel mutations and may rely on “toxin sponge” proteins

Many poisonous organisms carry small-molecule toxins that alter voltage-gated sodium channel (NaV) function. Among these, batrachotoxin (BTX) from Pitohui poison birds and Phyllobates poison frogs stands out because of its lethality and unusual effects on NaV function. How these toxin-bearing organisms avoid autointoxication remains poorly understood. In poison frogs, a NaV DIVS6 pore-forming helix N-to-T mutation has been proposed as the BTX resistance mechanism. Here, we show that this variant is absent from Pitohui and poison frog NaVs, incurs a strong cost compromising channel function, and fails to produce BTX-resistant channels in poison frog NaVs. We also show that captivity-raised poison frogs are resistant to two NaV-directed toxins, BTX and saxitoxin (STX), even though they bear NaVs sensitive to both. Moreover, we demonstrate that the amphibian STX “toxin sponge” protein saxiphilin is able to protect and rescue NaVs from block by STX. Taken together, our data contradict the hypothesis that BTX autoresistance is rooted in the DIVS6 N→T mutation, challenge the idea that ion channel mutations are a primary driver of toxin resistance, and suggest the possibility that toxin sequestration mechanisms may be key for protecting poisonous species from the action of small-molecule toxins