8 research outputs found
Search for CP violation in charm meson decay
We report the results of a search for CP-violating decay rate asymmetries (ACP) in the charm decay modes D+\u2192K-K+pi+, D+\u2192K\uaf*0K+, D+\u2192phi pi+, and D0\u2192K+K-. Our measurements are all consistent with zero asymmetry: ACP(KKpi)=-0.031\ub10.068, ACP(K*K)=-0.12\ub10.13, ACP(phi pi)=0.066\ub10.086, and ACP(KK)=0.024\ub10.084. The data were accumulated by the Fermilab high energy photoproduction experiment E68
MEASUREMENT OF THE LAMBDA-C+ LIFETIME
A precise measurement of the \u39bc+ lifetime using approximately 1340 fully reconstructed \u39bc+\u2192pK-\u3c0+ and charge conjugate decays is presented. The data were accumulated by the Fermilab high energy photoproduction experiment E687. The lifetime of the \u39bc+ is measured to be 0.215\ub10.016\ub10.008 p
PRECISE MEASUREMENT OF THE D(S)+/- MESON LIFETIME.
A precise measurement of the Ds\ub1 meson lifetime is reported. The data were accumulated by the high energy photoproduction experiment E687 at Fermilab in the 1990\u20131991 fixed target run. The measurement has been done using 900 fully reconstructed Ds\ub1\u2192phi pi\ub1 decays. The lifetime of the Ds\ub1 meson is measured to be 0.475\ub10.020\ub10.007 p
MEASUREMENT OF THE LIFETIME OF THE XI(C)(0)
A measurement of the lifetime of the charmed strange baryon XIc0 is presented. The data were accumulated by the Fermilab high energy photoproduction experiment E687. The measurement has been made using 42\ub110 XIc0\u2192XI-pi+ decays. The lifetime of the XIc0 is measured to be 0.101-0.017+0.025\ub10.005 ps and its mass is measured to be 2462.1\ub13.1\ub11.4 MeV/c
MEASUREMENT OF THE MASS AND LIFETIME OF THE XIc+
Measurements of the mass and lifetime of the \u39ec+ decaying into \u39e-pi+pi+ are presented. The data were accumulated by the Fermilab high-energy photoproduction experiment E687. The mass of the \u39ec+ is measured to be 2464.4\ub12.0\ub11.4 MeV/c2 and the lifetime is measured to be 0.41-0.08+0.11\ub10.02 ps
Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci
<p>Nearly three-quarters of the 143 genetic signals associated with platelet and erythrocyte phenotypes identified by meta-analyses of genome-wide association (GWA) studies are located at non-protein-coding regions. Here, we assessed the role of candidate regulatory variants associated with cell type-restricted, closely related hematological quantitative traits in biologically relevant hematopoietic cell types. We used formaldehyde-assisted isolation of regulatory elements followed by next-generation sequencing (FAIRE-seq) to map regions of open chromatin in three primary human blood cells of the myeloid lineage. In the precursors of platelets and erythrocytes, as well as in monocytes, we found that open chromatin signatures reflect the corresponding hematopoietic lineages of the studied cell types and associate with the cell type-specific gene expression patterns. Dependent on their signal strength, open chromatin regions showed correlation with promoter and enhancer histone marks, distance to the transcription start site, and ontology classes of nearby genes. Cell type-restricted regions of open chromatin were enriched in sequence variants associated with hematological indices. The majority (63.6%) of such candidate functional variants at platelet quantitative trait loci (QTLs) coincided with binding sites of five transcription factors key in regulating megakaryopoiesis. We experimentally tested 13 candidate regulatory variants at 10 platelet QTLs and found that 10 (76.9%) affected protein binding, suggesting that this is a frequent mechanism by which regulatory variants influence quantitative trait levels. Our findings demonstrate that combining large-scale GWA data with open chromatin profiles of relevant cell types can be a powerful means of dissecting the genetic architecture of closely related quantitative traits.</p>