Angular momentum exchange between coherent light and matter fields

Full, three dimensional, time-dependent simulations are presented demonstrating the quantized transfer of angular momentum to a Bose-Einstein condensate from a laser carrying orbital angular momentum in a Laguerre-Gaussian mode. The process is described in terms of coherent Bragg scattering of atoms from a chiral optical lattice. The transfer efficiency and the angular momentum content of the output coupled vortex state are analyzed and compared with a recent experiment.Comment: 4 pages, 4 figure

Long-term methimazole therapy in Graves' hyperthyroidism and adverse reactions: a Danish multicenter study

PURPOSE: In this prospective multicenter study with patients newly diagnosed with Graves’ hyperthyroidism (GH), we studied the timing and characteristics of adverse drug reactions in patients treated with anti-thyroid drugs (ATD) for up to 48 months. METHODS: Patients with GH were treated with ATD until remission and hereafter with a low-dose regime to keep the patients in remission. The patients were followed with blood samples and recording of adverse events approximately every second month for the first 2 years and every third month for the following 2 years. RESULTS: We included 208 patients and the patients were treated for a median of 22 (range: 0.5–49) months. Ten percent of the patients experienced adverse drug reactions and 75% of the cases occurred during the first 6 months. After 24 months, the methimazole dose was lowered to 5 mg/day, and after this time point, no further adverse drug reactions were recorded. Skin reactions were the most prominent reaction, comprising 68% of the registered reactions, and no hepatic and bonemarrow affection was recorded. CONCLUSION: With this study, we report the frequency, timing of occurrence, and characteristics of adverse drug reactions when treating GH with the ATD drug methimazole for up to 48 months. Long-term low-dose methimazole treatment can be a cost-effective and straightforward treatment option if adverse drug reactions such as severe hepatic and bone marrow affection are kept in mind

Theory of the optical absorption of light carrying orbital angular momentum by semiconductors

We develop a free-carrier theory of the optical absorption of light carrying orbital angular momentum (twisted light) by bulk semiconductors. We obtain the optical transition matrix elements for Bessel-mode twisted light and use them to calculate the wave function of photo-excited electrons to first-order in the vector potential of the laser. The associated net electric currents of first and second-order on the field are obtained. It is shown that the magnetic field produced at the center of the beam for the $\ell=1$ mode is of the order of a millitesla, and could therefore be detected experimentally using, for example, the technique of time-resolved Faraday rotation.Comment: Submitted to Phys. Rev. Lett. (23 Jan 2008

Static Properties of Trapped Bose-Fermi Mixed Condensate of Alkali Atoms

Static properties of a bose-fermi mixture of trapped potassium atoms are studied in terms of coupled Gross-Pitaevskii and Thomas-Fermi equations for both repulsive and attractive bose-fermi interatomic potentials. Qualitative estimates are given for solutions of the coupled equations, and the parameter regions are obtained analytically for the boson-density profile change and for the boson/fermion phase separation. Especially, the parameter ratio $R_{int}$ is found that discriminates the region of the large boson-profile change. These estimates are applied for numerical results for the potassium atoms and checked their consistency. It is suggested that a small fraction of fermions could be trapped without an external potential for the system with an attractive boson-fermion interaction.Comment: 8 pages,5 figure

Rapidity and centrality dependence of particle production for identified hadrons in Cu+Cu collisions at sNN=200\sqrt{s_{NN}} = 200 GeV

The BRAHMS collaboration has measured transverse momentum spectra of pions, kaons, protons and antiprotons at rapidities 0 and 3 for Cu+Cu collisions at $\sqrt{s_{NN}} = 200$ GeV. As the collisions become more central the collective radial flow increases while the temperature of kinetic freeze-out decreases. The temperature is lower and the radial flow weaker at forward rapidity. Pion and kaon yields with transverse momenta between 1.5 and 2.5 GeV/c are suppressed for central collisions relative to scaled $p+p$ collisions. This suppression, which increases as the collisions become more central is consistent with jet quenching models and is also present with comparable magnitude at forward rapidity. At such rapidities initial state effects may also be present and persistence of the meson suppression to high rapidity may reflect a combination of jet quenching and nuclear shadowing. The ratio of protons to mesons increases as the collisions become more central and is largest at forward rapidities.Comment: 19 pages, 11 figures and 6 table

Cover crop composition mediates the constraints and benefits of roller crimping and incorporation in organic white cabbage production

Roller-crimping of cover crops grown during winter may facilitate reduced tillage efforts in organic vegetable production. A one-year field experiment was conducted twice (autumn 2015-2017) in sandy loam soil in Denmark testing two cover crop termination systems, roller-crimping (RC) without tillage before crop planting, and full incorporation by tillage (FI) of mowed cover crops in organic white cabbage (Brassica oleracea L. convar. capitata var. capitata f. alba) production. Three legume species were investigated: winter faba bean (Vicia faba L.), winter pea (Pisum sativum L.), hairy vetch (Vicia villosa Roth), in pure stands or in a mixture with winter rye (Secale cereale L.). Roller-crimping reduced total white cabbage biomass by 31% (2016) and 19% (2017). Marketable white cabbage yield was 100% (2016) or 24% (2017) lower under RC than FI, likely caused by delayed N release from cover crops and reduced soil dehydrogenase activity. White cabbage root growth was reduced by RC following pea/rye, where N availability was low. Despite reduced root growth and yield, RC still had the advantage of reducing weed growth by 63% compared with FI three weeks after cover crop termination in 2017 and of decreasing N leaching risk, indicated by reduced soil mineral N content in 0.5-1.5 m depth in autumn. Marketable yield was 35% higher following legumes compared with legume/rye mixtures in both termination systems in 2017, due to 105 kg N ha−1 higher mineral soil N content in 0-2.5 m depth in the spring and faster N mineralisation from plant material with a lower C/N ratio. This yield increase corresponded with increased root growth following RC legumes. In contrast, legume/rye mixtures had the advantage of decreasing weed growth by 50-68% and N leaching risk by 22 kg ha−1 in 0.5−2 m depth. Although RC demonstrated ecological benefits such as weed suppression and indicated reduced N leaching risk, the trade-off with yield losses could create a barrier to adoption. This trade-off could be mitigated by using pure legume cover crops and by improving management of supplemental N fertility

Offshore Code Comparison Collaboration within IEA Wind Task 23: Phase IV Results Regarding Floating Wind Turbine Modeling

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Rapidity dependence of deuteron production in Au+Au collisions at sNN\sqrt{s_{NN}} = 200 GeV

We have measured the distributions of protons and deuterons produced in high energy heavy ion Au+Au collisions at RHIC over a very wide range of transverse and longitudinal momentum. Near mid-rapidity we have also measured the distribution of anti-protons and anti-deuterons. We present our results in the context of coalescence models. In particular we extract the "volume of homogeneity" and the average phase-space density for protons and anti-protons. Near central rapidity the coalescence parameter $B_2(p_T)$ and the space averaged phase-space density $(p_T)$ are very similar for both protons and anti-protons. For protons we see little variation of either $B_2(p_T)$ or the space averaged phase-space density as the rapidity increases from 0 to 3. However both these quantities depend strongly on $p_T$ at all rapidities. These results are in contrast to lower energy data where the proton and anti-proton phase-space densities are different at $y$=0 and both $B_2$ and $f$ depend strongly on rapidity.Comment: Document updated after proofs received from PR

Glymphatic-assisted perivascular brain delivery of intrathecal small gold nanoparticles

Nanoparticles are ultrafine particulate matter having considerable potential for treatment of central nervous system (CNS) disorders. Despite their tiny size, the blood-brain barrier (BBB) restricts their access to the CNS. Their direct cerebrospinal fluid (CSF) administration bypasses the BBB endothelium, but still fails to give adequate brain uptake. We present a novel approach for efficient CNS delivery of 111In-radiolabelled gold nanoparticles (AuNPs; 10-15 nm) via intra-cisterna magna administration, with tracking by SPECT imaging. To accelerate CSF brain influx, we administered AuNPs intracisternally in conjunction with systemic hypertonic saline, which dramatically increased the parenchymal AuNP uptake, especially in deep brain regions. AuNPs entered the CNS along periarterial spaces as visualized by MRI of gadolinium-labelled AuNPs and were cleared from brain within 24 h and excreted through the kidneys. Thus, the glymphatic-assisted perivascular network augment by systemic hypertonic saline is a pathway for highly efficient brain-wide distribution of small AuNPs.Peer reviewe