A Conceptual Modelling Approach to Visualising Linked Data

Increasing numbers of Linked Open Datasets are being published, and many possible data visualisations may be appropriate for a user's given exploration or analysis task over a dataset. Users may therefore find it difficult to identify visualisations that meet their data exploration or analyses needs. We propose an approach that creates conceptual models of groups of commonly used data visualisations, which can be used to analyse the data and users' queries so as to automatically generate recommendations of possible visualisations. To our knowledge, this is the first work to propose a conceptual modelling approach to recommending visualisations for Linked Data

Clinical and laboratory features associated with macrophage activation syndrome in Still’s disease: data from the international AIDA Network Still’s Disease Registry

To characterize clinical and laboratory signs of patients with Still's disease experiencing macrophage activation syndrome (MAS) and identify factors associated with MAS development. Patients with Still's disease classified according to internationally accepted criteria were enrolled in the AutoInflammatory Disease Alliance (AIDA) Still's Disease Registry. Clinical and laboratory features observed during the inflammatory attack complicated by MAS were included in univariate and multivariate logistic regression analysis to identify factors associated to MAS development. A total of 414 patients with Still's disease were included; 39 (9.4%) of them developed MAS during clinical history. At univariate analyses, the following variables were significantly associated with MAS: classification of arthritis based on the number of joints involved (p = 0.003), liver involvement (p = 0.04), hepatomegaly (p = 0.02), hepatic failure (p = 0.01), axillary lymphadenopathy (p = 0.04), pneumonia (p = 0.03), acute respiratory distress syndrome (p < 0.001), platelet abnormalities (p < 0.001), high serum ferritin levels (p = 0.009), abnormal liver function tests (p = 0.009), hypoalbuminemia (p = 0.002), increased LDH (p = 0.001), and LDH serum levels (p < 0.001). At multivariate analysis, hepatomegaly (OR 8.7, 95% CI 1.9-52.6, p = 0.007) and monoarthritis (OR 15.8, 95% CI 2.9-97.1, p = 0.001), were directly associated with MAS, while the decade of life at Still's disease onset (OR 0.6, 95% CI 0.4-0.9, p = 0.045), a normal platelet count (OR 0.1, 95% CI 0.01-0.8, p = 0.034) or thrombocytosis (OR 0.01, 95% CI 0.0-0.2, p = 0.008) resulted to be protective. Clinical and laboratory factors associated with MAS development have been identified in a large cohort of patients based on real-life data. © 2023, The Author(s)

La consulenza medico legale e la responsabilit\ue0 del Perito/CTU Odontoiatra.

L\u2019odontoiatria ha l\u2019obiettivo di ripristinare lo stato di salute del cavo orale migliorando le funzionalit\ue0 dell\u2019apparato stomatognatico. L\u2019odontoiatra deve possedere tutte quelle regole di buona condotta, tecnica, deontologica e morale, a cui qualunque professionista dovrebbe attenersi nello svolgimento della propria attivit\ue0. La professione odontoiatrica pu\uf2 anche contemplare attivit\ue0 medicolegale in ambito di responsabilit\ue0 medica, sia civile che penale. E questo sia che l\u2019odontoiatra svolga la funzione di ausiliario del medico legale che in qualit\ue0 di consulente tecnico d\u2019ufficio ovvero perito. Tale attivit\ue0 deve coniugare l\u2019applicazione di conoscenze biologiche e tecniche delle scienze odontoiatriche con una adeguata preparazione nell\u2019ambito della dottrina giuridica e medico legale. Il consulente tecnico/perito odontoiatra incorre infatti in precise responsabilit\ue0 quando svolge l\u2019incarico affidatogli dal giudice e le possibili conseguenze per non aver saputo svolgere correttamente il predetto incarico sono specificatamente previste dalla legge penale e civile a seconda del sistema giudiziario nazionale. \uc8 opinione degli autori che gli odontoiatri che intendono partecipare all\u2019amministrazione della Giustizia abbiano una maggiore presa di coscienza dei propri limiti in assenza di quei presupposti culturali e metodologici che caratterizzano la medicina legale. A nostro parere il modo migliore per valutare una responsabilit\ue0 professionale odontoiatrica \ue8 attraverso la consulenza collegiale di un medico legale e di un odontoiatra esperto in medicina legale e odontologia forense. Solo l\u2019odontoiatra che avr\ue0 frequentato idonei strumenti formativi di tipo medico-giuridico potr\ue0 ritenersi sufficientemente pronto ad affrontare autonomamente casi di responsabilit\ue0 professionale e specifici ambiti tecnico-forensi finalizzati alla identificazione personale e all\u2019analisi di lesioni da morso umano

OSCAR: A Customisable Tool for Free-Text Search over SPARQL Endpoints

SPARQL is a very powerful query language for RDF data, which can be used to retrieve data following specific patterns. In order to foster the availability of scholarly data on the Web, several project and institutions make available Web interfaces to SPARQL endpoints so as to enable a user to search for information in the RDF datasets they expose using SPARQL. However, SPARQL is quite complex to learn, and usually it is fully accessible only to experts in Semantic Web technologies, remaining completely obscure to ordinary Web users. In this paper we introduce OSCAR, the OpenCitations RDF Search Application, which is a user-friendly search platform that can be used to search any RDF triplestore providing a SPARQL endpoint, while hiding the complexities of SPARQL. We present its main features and demonstrate how it can be adapted to work with different SPARQL endpoints containing scholarly data, vis those provided by OpenCitations, ScholarlyData and Wikidata. We conclude by discussing the results of a user testing session that reveal the usability of the OSCAR search interface when employed to access information within the OpenCitations Corpus

Fall Detection in indoor environment with Kinect sensor

Falls are one of the major risks of injury for elderly living alone at home. Computer vision-based systems offer a new, low-cost and promising solution for fall detection. This paper presents a new fall-detection tool, based on a commercial RGB-D camera. The proposed system is capable of accurately detecting several types of falls, performing a real time algorithm in order to determine whether a fall has occurred. The proposed approach is based on evaluating the contraction and the expansion speed of the width, height and depth of the 3D human bounding box, as well as its position in the space. Our solution requires no pre-knowledge of the scene (i.e. the recognition of the floor in the virtual environment) with the only constraint about the knowledge of the RGB-D camera position in the room. Moreover, the proposed approach is able to avoid false positive as: sitting, lying down, retrieve something from the floor. Experimental results qualitatively and quantitatively show the quality of the proposed approach in terms of both robustness and background and speed independence

Age estimation by pulp/tooth ratio in lateral and central incisors by peri-apical X-ray

Since 2004, several papers on the analysis of the apposition of secondary dentine have been published. The aim of this paper was to study a sample of peri-apical X-ray images of upper and lower incisors, both lateral and medial, to examine the application of pulp/tooth area ratio as an indicator of age. A sample of 116 individuals, 62 men and 54 women, aged between 18 and 74 years, was studied. Data were fitted with age as a linear function of the pulp/tooth ratio of incisors. The total variance explained by the regression equation ranged from 51.3% of age, when lower lateral incisors were used as explanatory variable, to 81.6% when upper lateral incisors were used. The accuracy of the corresponding regression model yielded ME = 8.44 and 5.34 years, respectively. These results show that, although incisors are less reliable than canines or lower premolars, they can be used to estimate age-at-death when the latter are absent

Physicochemical properties and antimicrobial activity of new spirocyclic thieno[2,3-d]pyrimidin-4(3H)-one derivatives

(figure presented) A number of 6'-methylidene-2,3-dihydro-1H-spiro[pyridine-4,5'-thieno[2,3-d]pyrimidin]-4'(3'H)-one derivatives, obtained as major products of a domino reaction between 5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidines and electron-deficient alkynes, were characterized for their acid-base properties and lipophilicity and evaluated for the antimicrobial activity against a number of clinical isolates of bacterial and fungal strains. The cytotoxicity against four tumor cell lines was also screened for some compounds. The dissociation constants (pKa) and partition coefficients (log P) in 1-octanol–water system were determined using a potentiometric technique. The negative difference between the observed and calculated log P values could be explained in the light of the conformational rigidity. Most of the studied compounds showed a moderate and selective activity against Gram-positive bacteria strains (S. agalactiae, E. faecalis, S. epidermidis), whereas did not exhibit any effect against Gram-negative bacteria and fungi at the maximum test concentration (500 μM). Implications of the physicochemical properties in modulating the antimicrobial activity and cytotoxicity of the examined spirocyclic thieno[2,3-d]pyrimidin-4(3H)-one derivatives are also discussed. © 2017 Springer Science+Business Media New York

Physicochemical properties and antimicrobial activity of new spirocyclic thieno[2,3-d]pyrimidin-4(3H)-one derivatives

(figure presented) A number of 6'-methylidene-2,3-dihydro-1H-spiro[pyridine-4,5'-thieno[2,3-d]pyrimidin]-4'(3'H)-one derivatives, obtained as major products of a domino reaction between 5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidines and electron-deficient alkynes, were characterized for their acid-base properties and lipophilicity and evaluated for the antimicrobial activity against a number of clinical isolates of bacterial and fungal strains. The cytotoxicity against four tumor cell lines was also screened for some compounds. The dissociation constants (pKa) and partition coefficients (log P) in 1-octanol–water system were determined using a potentiometric technique. The negative difference between the observed and calculated log P values could be explained in the light of the conformational rigidity. Most of the studied compounds showed a moderate and selective activity against Gram-positive bacteria strains (S. agalactiae, E. faecalis, S. epidermidis), whereas did not exhibit any effect against Gram-negative bacteria and fungi at the maximum test concentration (500 μM). Implications of the physicochemical properties in modulating the antimicrobial activity and cytotoxicity of the examined spirocyclic thieno[2,3-d]pyrimidin-4(3H)-one derivatives are also discussed. © 2017 Springer Science+Business Media New York