141 research outputs found
Stereoselective synthesis of chiral β2,3-disubstituted-β-amino acid derivatives using Pd/In transmetallation cascade processes
A new, highly efficient synthesis of chiral β2,3-disubstituted-β-amino acid derivatives has been developed, based on an allylation procedure employing allene and a catalytic Pd/In bimetallic process
Reactive organoallyl species generated from aryl halides and allene: allylation of alpha,beta-unsaturated aldehydes and cyclic ketones employing Pd/In transmetallation processes
Allylation of α,β-unsaturated aldehydes and cyclic ketones promoted by Pd/In transmetallation processes has been studied. The unsaturated aldehydes underwent regioselective 1,2-addition to afford secondary homoally alcohols. The reactions have been performed using Pd(OAc)2/PPh3 as catalytic system and metallic indium affording the products in good yields. The same transformation with unsaturated ketones proved to be less efficient, while saturated cyclic ketones delivered generally excellent yields in the presence of CuI. In these latter processes the presence of a distal heteroatom influences the reaction rate
ChemInform Abstract: Control of the Regioselectivity in Palladium(O)-Catalyzed Allylic Alkylation
ChemInform Abstract: Regio- and Enantioselective Carbolithiation of Non-Activated C=C Bonds.
Total Synthesis of Tiacumicin B. Study of the Challenging béta-Glycosylations
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A New Route to 2-C- and 4-C-Branched Sugars by Palladium—Indium Bromide-Mediated Carbonyl Allylation.
ChemInform Abstract: Control of the Regioselectivity in Palladium(0)-Catalyzed Allylic Alkylation
ChemInform Abstract: Enantioselective Carbolithiation of Cinnamyl Acetals. New Access to Chiral Disubstituted Cyclopropanes.
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