54 research outputs found

    A Possible Spin-Orbit Misalignment in the Transiting Eccentric Planet HD 17156b

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    We present simultaneous photometric and spectroscopic observations of HD 17156b spanning a transit on UT 2007 November 12. This system is of special interest because of its 21-day period (unusually long for a transiting planet) and its high orbital eccentricity of 0.67. By modeling the Rossiter-McLaughlin effect, we find the angle between the sky projections of the orbital axis and the stellar rotation axis to be 62±2562^{\circ} \pm 25^{\circ}. Such a large spin-orbit misalignment, as well as the large eccentricity, could be explained as the relic of a previous gravitational interaction with other planets.Comment: 5 pages, 2 figures, 3 tables. Accepted for publication in PASJ Letters (Vol. 60, No. 2

    A Phase II Study of S-1 Monotherapy as a First-line Combination Therapy of S-1 Plus Cisplatin as a Second-line Therapy, and Weekly Paclitaxel Monotherapy as a Third-line Therapy in Patients with Advanced Gastric Carcinoma: A Second Report

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    Background We have previousy reported on a Phase II study of S-1 monotherapy as a first line, combination therapy of S-1 plus cisplatin as a second line, and weekly paclitaxel monotherapy as a third line therapy in patients with advanced gastric carcinomas. The median survival time (MST) of patients over the whole course of treatment was not previously calculated because 12 out of 19 patients had not yet succumbed. Since then, we have calculated the MST for this study and herein report our findings. Patients and Methods Between 2002 and 2005, 19 patients were enrolled in this study. Chemotherapy consisted of either 60 mg/m 2 of S-1 for 4 weeks at 6-week intervals, a combination of 60 mg/m 2 S-1 for 3 weeks and 60 mg/m 2 cisplatin on day 8 at 5-week intervals, or 60 mg/m 2 paclitaxel at days 1, 8, and 15, at 4-week intervals. The regimens were repeated until the occurrence of unacceptable toxicities, disease progression, or patient noncompliance. The primary end point was the overall survival. Results The median survival time was 774 days. The response rates were 33.3% (3/9), 12.5% (1/8), and 0% (0/4) after the first, second, and third line chemotherapies, respectively. The major adverse hematological toxicity was leukopenia, which reached grades 3–4 in all lines of chemotherapy investigated. In addition, the major adverse non-hematological toxicity was anorexia, which reached grade 3–4 in second line chemotherapy, and no deaths were attributable to the adverse effects of the drugs. Conclusion This sequential therapy was an effective treatment for advanced gastric cancer with acceptable toxic side-effects. We considered this therapy to be effective because of the smooth transition to the next regimen

    Current Performance and On-Going Improvements of the 8.2 m Subaru Telescope

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    An overview of the current status of the 8.2 m Subaru Telescope constructed and operated at Mauna Kea, Hawaii, by the National Astronomical Observatory of Japan is presented. The basic design concept and the verified performance of the telescope system are described. Also given are the status of the instrument package offered to the astronomical community, the status of operation, and some of the future plans. The status of the telescope reported in a number of SPIE papers as of the summer of 2002 are incorporated with some updates included as of 2004 February. However, readers are encouraged to check the most updated status of the telescope through the home page, http://subarutelescope.org/index.html, and/or the direct contact with the observatory staff.Comment: 18 pages (17 pages in published version), 29 figures (GIF format), This is the version before the galley proo

    100m疾走の後半における走スピード, ピッチおよびストライドの変化

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    本研究では, 成人男子7名を被験者にして, 100m疾走中の後半における走スピード, ピッチ数およびストライド長の変化を明らかにした。本研究で得られた結果は, 次のように要約できる。1) 100m疾走後半の50mから100mまで, 走スピードは減少し続けた。2) 100m疾走後半の50mから100mまで, ピッチ数は減少し続けた。3) 100m疾走後半の50mから90mまでストライド長はほぼ一定を保ったが, 90mから100mまでの区間ではストライド長は急激に増加した。The purpose of this study was to measure running speed, stride length and step frequecny in the latter half of 100m sprint running. The subjects used in this study were four collegiate jumpers, 2 graduate students and an assistant of Chukyo University. All were healthy males. Each run was filmed at 50 frames/sec with Photosonics and Bolex 16mm cameras. Stride length and step frequency was measured from film analysis. Resultes obtanied from this study were summarized as follows. 1. Running speed and step frquency were gradually decreased in the latter half 50m of 100m sprint running. 2. Stride length was almost constant from 50m to 90m. After that, however, it was significantly decreased

    Effect of wall shear rate on thrombogenesis in microvessels of the rat mesentery

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