The Contemplative Counselor: A Way of Being (Minneapolis, MN: Fortress Press, 2011)

Reviewed by Joseph D. Driskill

Tratamiento de la demodicosis canina generalizada con dosis reducidas de ivermectina oral

La administración diaria de ivermectina a dosis altas (0,6 mg/kg) es la mejor alternativa disponible para tratar aquellos casos de sarna demodécica resistente al almiraz

Non-Normality as a Predictor of Participation in Bullying: Valuation in Victims and Aggressors

Bullying is related to several variables, including diversity and variables that place the victim outside of normality. However, it is not easy to find a single meaning of normality. The present study has two main objectives: to find out whether victims are evaluated as non-normal and to find out whether aggressors are evaluated as non-normal. A cross-sectional, correlational, and quantitative study was designed, focusing on a representative sample of secondary school students from the Community of Madrid. The sample consisted of 2076 participants and was constructed using a stratified, proportional, and random sampling technique. To gather this information, a questionnaire was constructed. It includes a first section where sociodemographic and normality information is collected, and a second section made up of the Defensor del pueblo-UNICEF Bullying Questionnaire. The reliability and consistency of the questionnaire are acceptable (Cronbach’s alpha 0.91). For the comparison of means between groups, a Student’s t-test was applied, and the correlation between variables was calculated by applying the bivariate correlation test. Results show that victims are evaluated as non-normal while aggressors are perceived as normal. This implies that the risk of being involved in bullying situations as a victim can be predicted. © 2022 by the authors. Licensee MDPI, Basel, Switzerland

Literatura e cultura na obra: “Ponta Porã – polca, churrasco e chimarrão” de Elpídio Reis

ResumoEste trabalho visa divulgar a obra do escritor regionalista sul-mato-grossense Elpídio Reis. Trata-se de escritor regionalista cujo nome e obra mostram-se de significativa produtividade para os Estudos Culturais e para a região da fronteira Brasil-Paraguai. Originariamente, essas reflexões são, ainda, resultados do nosso projeto de pesquisa institucional, intitulado: “Manifestações Literárias no Estado de Mato Grosso do Sul”, projeto esse que tem como objetivo, a inserção da literatura e cultura regionais nos parâmetros curriculares do Estado do MS. A literatura e cultura no extremo oeste brasileiro, mais precisamente na fronteira Brasil - Paraguai no Mato Grosso do Sul, estão representadas na obra “Ponta Porã – Polca, Churrasco e Chimarrão”, destacando o nosso lugar de enunciação e de pertencimento, o que resulta em um composto cultural híbrido. Em se tratando da literatura e das artes sul-mato-grossenses encontramos representações profundas da identidade cultural do nosso Estado. Obra que retrata diversos retalhos culturais e nos transportam para outras realidades que se encontram em fronteiras imaginárias e simbólicas. Segundo Capraro (2006), as obras de literatura de fronteira excedem os limites da escrita acadêmica, como regras subentendidas à historiografia ou semiótica, mas, ao mesmo tempo, arroga um compromisso com a realidade social e histórica.Palavras-chave: Literatura Sul-mato-grossense; Identidade cultural; Fronteira; Elpídio Reis. 

Literatura e cultura na obra: “Ponta Porã – polca, churrasco e chimarrão” de Elpídio Reis

Resumo Este trabalho visa divulgar a obra do escritor regionalista sul-mato-grossense Elpídio Reis. Trata-se de escritor regionalista cujo nome e obra mostram-se de significativa produtividade para os Estudos Culturais e para a região da fronteira Brasil-Paraguai. Originariamente, essas reflexões são, ainda, resultados do nosso projeto de pesquisa institucional, intitulado: “Manifestações Literárias no Estado de Mato Grosso do Sul”, projeto esse que tem como objetivo, a inserção da literatura e cultura regionais nos parâmetros curriculares do Estado do MS. A literatura e cultura no extremo oeste brasileiro, mais precisamente na fronteira Brasil - Paraguai no Mato Grosso do Sul, estão representadas na obra “Ponta Porã – Polca, Churrasco e Chimarrão”, destacando o nosso lugar de enunciação e de pertencimento, o que resulta em um composto cultural híbrido. Em se tratando da literatura e das artes sul-mato-grossenses encontramos representações profundas da identidade cultural do nosso Estado. Obra que retrata diversos retalhos culturais e nos transportam para outras realidades que se encontram em fronteiras imaginárias e simbólicas. Segundo Capraro (2006), as obras de literatura de fronteira excedem os limites da escrita acadêmica, como regras subentendidas à historiografia ou semiótica, mas, ao mesmo tempo, arroga um compromisso com a realidade social e histórica. Palavras-chave: Literatura Sul-mato-grossense; Identidade cultural; Fronteira; Elpídio Reis

Optimization of the tartrate-resistant acid phosphatase detection by histochemical method

According to the new kidney disease improving global outcomes (KDIGO) guidelines, the term of renal osteodystrophy, should be used exclusively in reference to the invasive diagnosis of bone abnormalities. Due to the low sensitivity and specificity of biochemical serum markers of bone remodelling, the performance of bone biopsies is highly stimulated in dialysis patients and after kidney transplantation. The tartrate-resistant acid phosphatase (TRACP) is an iso-enzyme of the group of acid phosphatases, which is highly expressed by activated osteoclasts and macrophages. TRACP in osteoclasts is in intracytoplasmic vesicles that transport the products of bone matrix degradation. Being present in activated osteoclasts, the identification of this enzyme by histochemistry in undecalcified bone biopsies is an excellent method to quantify the resorption of bone. Since it is an enzymatic histochemical method for a thermolabile enzyme, the temperature at which it is performed is particularly relevant. This study aimed to determine the optimal temperature for identification of TRACP in activated osteoclasts in undecalcified bone biopsies embedded in methylmethacrylate. We selected 10 cases of undecalcified bone biopsies from hemodialysis patients with the diagnosis of secondary hyperparathyroidism. Sections of 5 µm were stained to identify TRACP at different incubation temperatures (37°, 45°, 60°, 70° and 80°C) for 30 minutes. Activated osteoclasts stained red and trabecular bone (mineralized bone) was contrasted with toluidine blue. This approach also increased the visibility of the trabecular bone resorption areas (Howship lacunae). Unlike what is suggested in the literature and in several international protocols, we found that the best results were obtained with temperatures between 60°C and 70°C. For technical reasons and according to the results of the present study, we recommended that, for an incubation time of 30 min, the reaction should be carried out at 60°C. As active osteoclasts are usually scarce in a bone section, the standardization of the histochemistry method is of great relevance, to optimize the identification of these cells and increase the accuracy of the histomosphometric results. Our results, allowing an increase in osteoclasts contrast, also support the use of semi-automatic histomorphometric measurements

Physically crosslinked polyvinyl alcohol hydrogels as synthetic cartilage materials

Abstract in proceedings of the Fourth International Congress of CiiEM: Health, Well-Being and Ageing in the 21st Century, held at Egas Moniz’ University Campus in Monte de Caparica, Almada, from 3–5 June 2019.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.info:eu-repo/semantics/publishedVersio

Metalloids in origin and evolution of life

Metalloids in origin and evolution of life. Metalloids have characteristics between metals and non-metals which give them, in some cases, specific properties. At least two of this chemical elements, boron and silicon, are essential to a significant number of living organisms and since some years ago it has been observed that the same metalloids may be involved in the synthesis and stabilization of some molecules relevant to the origin of life