411 research outputs found
INFLUÊNCIA DOS FATORES SOCIOECONÔMICOS NO DESENVOLVIMENTO DO PESO EM ESCOLARES DE FEIRA DE SANTANA-BA
Nas últimas décadas, importantes mudanças econômicas, sociais e tecnológicas propiciaram alterações no perfil epidemiológico das doenças nas sociedades modernas. Nesse cenário, variações nos indicadores nutricionais favoreceram um aumento significativo da obesidade, observado tanto em adultos quanto em crianças. Dados recentes do NCD Risk Factor Collaboration mostram que essa condição afeta cerca de 671 milhões de adultos no mundo, o que representa aproximadamente 10% da população mundial (NCD-RISC, 2017)
Salivary Alterations in Rats with Experimental Chronic Kidney Disease
Objective This study aimed to analyze changes in saliva composition and salivary secretion process of rats with chronic kidney disease induced by 5/6 nephrectomy to set the foundation for salivary studies related to CKD. Methods CKD was induced in Wistar rats via 5/6 nephrectomy. Blood and saliva samples were collected from Control, Sham and CKD groups at 8 and 12 weeks after the surgery. Salivation was stimulated via intraperitoneal injections of pilocarpine (1.0 mg/Kg body weight) or isoproterenol (5.0 mg/Kg body weight). Saliva was collected and immediately stored at -80 degrees C until analysis. The salivary flow rate, total protein, amylase and peroxidase activities, and urea concentrations were measured. The blood urea nitrogen (BUN) and serum creatinine concentrations were also evaluated. Results Increases in BUN and serum creatinine concentrations were observed in the CKD groups. Amylase activity was significantly reduced in response to both stimuli in the CKD groups at 8 weeks and increased in the CKD groups at 12 weeks in response to isoproterenol stimulus. The peroxidase activities of the CKD groups were significantly reduced in response to isoproterenol stimulation and were increased at 12 weeks in response to pilocarpine stimulation. Salivary urea was significantly increased in the CKD groups at 8 weeks in response to the isoproterenol stimuli and at 12 weeks in response to both salivary agonists. Conclusions The pattern of alterations observed in this experimental model is similar to those observed in patients and clearly demonstrates the viability of 5/6 nephrectomy as an experimental model in future studies to understand the alterations in salivary compositions and in salivary glands that are elicited by CKD.FAPESP (the Research Council for the State of Sao Paulo)Univ Sao Paulo, Dept Biomat & Biol Oral, Fac Odontol, Sao Paulo, BrazilEscola Paulista Med UNIFESP, Dept Fisiol, Sao Paulo, BrazilEscola Paulista Med UNIFESP, Dept Fisiol, Sao Paulo, BrazilFAPESP: 2013-18609-1Web of Scienc
Development and validation of a stability indicating HPLC method to determine diltiazem hydrochloride in tablets and compounded capsules
A stability indicating HPLC method to determine diltiazem hydrochloride (DTZ) in tablets and compounded capsules was developed and validated according to Brazilian and the International Conference on Harmonization (ICH) guidelines. The separation was carried out on a Purospher Star® C18 (150 x 4.6 mm i.d., 5 µm particle size, Merck Millipore) analytical column. The mobile phase consisted of a 0.05% (v/v) trifluoroacetic acid aqueous solution and a 0.05% trifluoroacetic acid methanolic solution (44:56, v/v). The flow rate was 1.0 mL.min-1 with a run time of 14 minutes. The detection of DTZ and degradation products (DP) was performed at 240 nm, using a diode array detector. The method proved to be linear, precise, accurate, selective, and robust, and was adequate for stability studies and routine quality control analyses of DTZ in tablets and compounded capsules
Proporcionando atualizações em nutrição para a comunidade - 53955031
Trabalho apresentado no 31º SEURS - Seminário de Extensão Universitária da Região Sul, realizado em Florianópolis, SC, no período de 04 a 07 de agosto de 2013 - Universidade Federal de Santa Catarina.A nutrição desportiva visa orientar para que a alimentação e a hidratação realizadas antes, durante e após as modalidades desportivas sejam de boas escolhas, favorecendo o bem-estar do indivíduo. Os escolares que apresentam melhor rendimento desportivo são aqueles que têm garantidos, em seus organismos, adequados suprimentos de energia, nutrientes e, de líquidos corporais, contribuindo para com o desenvolvimento de jogos escolares e as modalidades em aulas de educação física, que requerem esforço físico. É usual que muitas crianças e adolescentes não realizem o desjejum antes de irem à escola e, com isso, seu rendimento na atividade desportiva ficará aquém de seu potencial, caso não ingiram alimentos e tomem líquidos antes das aulas de educação física. O mesmo se aplica em situações de preparo de alunos para campeonatos estudantis, nos turnos inversos ao horário de aulas. A Nutrição se dedica a orientar para que as referidas escolhas alimentícias por escolares sejam saudáveis, apropriadas ao processo digestório do momento, promovam o aporte energético e de hidratação requeridos ao desporto, antes, durante e após a atividade física
Inhibition of the growth of major mastitis-causing pathogens by non-aureus Staphylococcus isolates using the cross-streaking method
Sustainable citizen decision-making:Impact of the cost-of-living crisis on the energy and circular economy transitions in urban Scotland
The present report is the outcome of a research project commissioned by Zero Waste Scotland and carried out by the Just Transition Hub (JTH), University of Dundee, with the objective of understanding the ways in which the cost-of-living crisis has affected the attitudes and behaviours of individuals and communities towards a transition to a low-carbon economy in Scotland. We define the transition as encompassing both energy transition and the transition to a circular economy, so in this report the word “transition(s)” means both the referred transitions. We define the scope of “justice” to cover three dimensions – distributive, recognition and procedural. Briefly, distributive justice concerns the ideal of a fair share of the benefits and costs of the transition among different communities and stakeholders. Recognition justice respects the proper acknowledgement of marginalised individuals and communities who may be living in deprived urban areas. Procedural justice respects inclusion and effective participation of all, including marginalised actors, in public debate and decision-making. The study involved a literature review in narrative form (chapter 2) and a smallscale exploratory study (chapters 3 and 4), using a multi-strategy approach that included seven individual semi-structured expert interviews, four semi-structured citizen/consumer focus groups and one semi-structured expert focus group. Both the literature review and the empirical research adopted a thematic analysis approach, with clear research objectives identified in a standardised analysis framework. The present research is part of a broader series of investigations commissioned by Zero Waste Scotland to understand circular economy perspectives and sustainable decision-making in times of crises to help inform Zero Waste Scotland’s communication, engagement and further research for a just transition. The present study is complemented by parallel research being conducted by the University of Highlands and Islands with a focus on rural communities
SOLAR ENERGY AND ITS GLOBAL INVESTMENTS
Este trabalho teve por objetivo analisar as pesquisas de energia solar em escala global nos últimos cinco anos a fim de identificar as formas de aplicação dessa fonte de energia e quais países estão participando das pesquisas na área solar. Neste contexto Foram analisadas as publicações sobre energia solar dos últimos cinco anos (2010 – 2015) de revistas científicas voltadas a temática de energias renováveis, sendo adotado o Fator de Impacto (FI) como critério de seleção. Os artigos foram analisados a nível de resumo para um universo amostral de mais de 350 publicações, das quais o índice do FI variou de 3 a 15. Os resultados mostram que os países com maior número de publicações na área de energia solar no mundo foram Índia, China, Espanha, Malásia e Estados Unidos, totalizando mais da metade das pesquisas mundiais. A energia solar térmica teve maior participação nas pesquisas e o ano de 2014 o maior número de publicações em relação a energia solar no mundo
Catarrhal mastitis by Staphylococcus simulans in a nulliparous goat
O presente trabalho é o relato do caso de uma cabra nulípara da raça Parda Alpina, de um ano de idade, pertencente ao Setor de Caprinocultura da Universidade Federal da Paraíba – Bananeiras - Brasil. Ambas as glândulas foram naturalmente infectadas por Staphylococcus simulans α-hemolítico. As glândulas mamárias apresentaram mastite aguda catarral com envolvimento sistêmico, respondendo positivamente ao tratamento sistêmico com gentamicina associada a amoxicilina. O presente relato sugere a importância do potencial patogênico de Staphylococcus não-aureus (SNA) como causador de mastite clínica também em animais nulíparos. O isolado mostrou resistência a tetraciclina e continha genes de produção de toxinas estafilocócicas (sec, seg e TSST-1). Além disso, tem sido relatado que Staphylococcus simulans é um patógeno emergente em seres humanos causando infecções cutâneas e osteoarticulares, principalmente naqueles que têm contato íntimo com animais de fazenda. Até onde sabemos, este é o primeiro relato de uma mastite clínica em uma cabra nulípara causada por Staphylococcus simulans.The present paper is a case report of a one-year old nulliparous Alpine Goat belonging to a dairy goat farm in semi-arid region of Brazil. Both glands were naturally infected by α-hemolytic Staphylococcus simulans and evolved similar clinical signs. The mammary glands presented an acute catarrhal mastitis with systemic clinical signs that responded positively to treatment with gentamicin associated with amoxicillin. The present report suggests the importance of the pathogenic potential of non-aureus Staphylococci strains (NAS) as a cause of clinical mastitis also in nulliparous animals. The isolate showed resistance to tetracycline and contained staphylococcal toxin production genes (sec, sec and TSST-1). Moreover, it has been reported that Staphylococcus simulans is an emerging pathogen in humans causing cutaneous and osteoarticular infections, mainly in those in close contact with farm animals. To the best of our knowledge, this is the first report of a clinical mastitis in a nulliparous goat caused by Staphylococcus simulans
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