Pattern and risk factors of non-fistulous urinary incontinence among gynaecological clinic attendees in a Nigeria tertiary health institution

Background: Urinary incontinence is the involuntary loss of urine. It is rarely disclosed by the patients and usually under-reported. Objective of this study was to determine the prevalence, pattern and risk factors of non-fistulous urinary incontinence among women attending gynaecological clinics in Calabar, Nigeria.Methods: This was a cross-sectional study of 658 women attending gynecological clinic from June 2018 to June 2019. English version of International consultation on incontinence questionnaire-urinary incontinence-short form (ICIQ-UI-SF) was used to obtain data. Statistical analysis was done using SPSS version 22.Results: The prevalence of urinary incontinence was 16.1%. Stress incontinence was the commonest of urinary incontinence (73.3%), other types were urge incontinence (17.2%) and mixed incontinence (9.5%). Independent risk factors for urinary incontinence were 40 years and above (AOR = 5.610; p<0.001), parity ≥3 (AOR = 4.454; p<0.001), lower educational level (primary) (AOR = 2.588; p<0.001), vaginal/instrumental deliveries (AOR = 4.358; p<0.001), carrying heavy load (AOR = 3.688; p<0.001) and farming (AOR = 3.510; p<0.001).Conclusions: Non-fistulous urinary incontinence is common among women in our environment. Stress urinary incontinence was the most common type. Advanced age, higher parity, vaginal and instrumental deliveries and farming were independent risk factors for urinary incontinence

Assessment of remediation Potentials of maize (Zea mays) on sites co-contaminated with Pb and antracene

Phytoremediation is a promising technology for the remediation of sites co-contaminated with inorganic and organic pollutants. A pot experiment was conducted to evaluate the remediation potential of Z.mays in soil co- contaminated with Pb and antracene. Pristine sandy loam soils were polluted with Pb chloride salt and antracene at three different levels (50mg/kg of Pb, 100mg/kg of Pb, and 100mg/kg of Pb+100mg/kg of antracene) and laid out in completely randomized design with 3 replicates. Shoot dry matter weight was significantly reduced (p≤0.05) when compared with control treatments by 40% when exposed to100mg kg-1 of Pb. There was a 48% inhibition of shoot dry matter of Z.mays relative to control treatments when 100 mg Pb kg-1 was mixed with 100 mgkg-1 antracene. Root and shoot metal concentration in Zea mays increased with increasing concentration of Pb. The average Translocation Factor (TF < 1 (0.69) obtained suggests that Zea mays predominantly retains Pb in the root portion of the plant. There was a 5% increase in shoot Pb concentration when soil was contaminated with Pb and antracene. The extractable antracene decreased significantly (p≤0.05) in soil planted with Z.mays as well as in pots without maize plant. This accounted for 65 and 72% of antracene dissipation in planted soil and 40-46% dissipation in unplanted soil. This result suggested that Zeamays is a promising candidate for uptake Pb and dissipation of antracene in co-contaminated soils

Biotransformation of Food Dyes by Human Intestinal Bacteria ( Streptococcus faecalis , Eschericia coli )

Biotransformation of food dyes (Tartrazine and Quinoline yellow) by Streptococcus faecalis and Eschericia coli isolated from human intestinal microflora was investigated. Decolourisation of the media containing the dyes was used as an index of biotransformation. Biotransformation was higher under aerobic than under anaerobic conditions. The results obtained were attributed to the organisms cytosolic flavin-dependent reductases and redox equivalents generated by metabolism of soluble starch which transfer electrons to the chromophoric group of the dyes. The potential health risk of the resulting colourless metabolites (aromatic amines) is under investigation. @JASE

MEAN VARIANCE OF FRACTIONAL STOCHASTIC MODEL AND LOGARITHM UTILITY OPTIMIZATION OF A PENSION FUND WITH TAX AND TRANSACTION COST

This work looked at the mean-variance of fractional continuous time stochastic model for the dynamics of a pension fund with tax and transaction cost, where the effect of tax and transaction cost charging makes on the expected logarithmic utility of the pensioner was established. The associated H-J-B equation in the optimization problem is obtained using lto’s lemma. An explicit solution to the pensioners’ problems was derived under stated condition

Application of ICT and Electronic Technology in Election Management: Challenges in Rural Areas in South-Eastern Nigeria

This paper has presented the applications of Information Communication Technology and election management. The study has reviewed several challenges and bottleneck encountered in the electoral democratic system in Nigeria election. During the study, the use of electronic technology adoption in the electoral process has actually reduced human involvement in election process; this is due to irregularities and incessant increase in violence among electorates, party agents and other stakeholders. The relevance of this paper is to address the integration of ICT as well as electronic digital devices in carryout electrons in Nigeria. The research was conducted in the rural areas of the South-Eastern Nigeria States, it was discovered that about 60% of the respondent stated that the use of electronic technology in the deployment to rural areas has inadequate trained personnel in effective handling of the gadgets, issues on the use of card reader malfunctioning was also sported out. It was recommended that the electoral bodies should sensitized, make adequate available of electronic devices for efficient and effective election management in Nigeria

Improving the Drug Bioavailability Property of Myricetin through a Structural Monosubstitution Modification Approach: an In-Silico Pharmacokinetics Study

Myricetin belongs to the members of polyphenolic compounds that make up the flavonoid class, which possess antioxidant properties. Myricetin is mostly obtained from vegetables, fruits, nuts, berries, tea, and is also found in red wine. It is also similar structurally to quercetin, fisetin and luteolin and is known to possess similar functions as the other members in the flavonol class of flavonoids. The health benefits of myricetin cuts across being an anticarcinogen compound to its antiviral, antithrombotic, antidiabetic, antiatherosclerotic, neuroprotective and anti-inflammatory properties among others. It also plays a role as a cyclooxygenase 1 inhibitor, an antineoplastic agent, an antioxidant, a plant metabolite, a food component and a hypoglycemic agent. It is a hexahydroxyflavone and a 7-hydroxyflavonol. The 2D structure of myricetin was obtained from the PubChem database while the MarvinSketch software was used to effect the various structural modifications on the compound. The structural modifications entails the substitution of the OH group attached to the C1 of myricetin with different functional groups such as the C=O, C2H5, CH3, CHO, CONH2, H and OCH3 which were saved as mrv files. The saved mrv files for each 2D structures were converted into canonical SMILES with the aid of the Open Babel software while the pharmacokinetic parameters for each compound was predicted using the SwissADME server. Results from this study showed that the C2H5, CH3 and H analogues of myricetin showed a higher gastrointestinal absorption rate compared to their C=O, CHO, CONH2 and OCH3 counterparts. This result shows that the C2H5, CH3 and H analogues of myricetin might be more orally bioavailable compared to myricetin and the other modified analogues. Preclinical studies on these compounds are therefore recommende