445 research outputs found
Practicing Invisibility: Women’s Roles in Higher Education
In this article, two female academics confront their role in producing their own invisibility and ir-relevance in the practice of higher education. Drawing on feminist standpoint theory, the authors interrogate their participation in articulation work that helped male colleagues to assume roles of higher status. Based on an analysis of personal narratives and the text of an international e-mail exchange that resulted in a successful grant proposal, the authors argue that the hierarchical and patriarchal cultural history of the academy as well as the intrusion of gendered relations from contexts beyond the institution of higher education undermine the democratic intentions of aca-demics, both male and female, who espouse horizontal collaborative relations between academics. This case study illustrates the contradiction between egalitarian institutional rhetoric and value systems of individuals and the hierarchical and gendered power relations that play out in everyday life in the academy. The authors conclude that while both male and female academics must work to change the gendered text of higher education, women in the academy must build both critical mass and mentoring networks in consciously acting to change the institution’s cultural history
Practicing Invisibility: Women’s Roles in Higher Education
In this article, two female academics confront their role in producing their own invisibility and ir-relevance in the practice of higher education. Drawing on feminist standpoint theory, the authors interrogate their participation in articulation work that helped male colleagues to assume roles of higher status. Based on an analysis of personal narratives and the text of an international e-mail exchange that resulted in a successful grant proposal, the authors argue that the hierarchical and patriarchal cultural history of the academy as well as the intrusion of gendered relations from contexts beyond the institution of higher education undermine the democratic intentions of aca-demics, both male and female, who espouse horizontal collaborative relations between academics. This case study illustrates the contradiction between egalitarian institutional rhetoric and value systems of individuals and the hierarchical and gendered power relations that play out in everyday life in the academy. The authors conclude that while both male and female academics must work to change the gendered text of higher education, women in the academy must build both critical mass and mentoring networks in consciously acting to change the institution’s cultural history
Playworlds as Ways of Being, A Chorus of Voices : Why are Playworlds Worth Creating? The Playworld of Creative Research
This paper discusses the playworlds of the Playworld of Creative Research (PWCR) research group. Playworlds are created from a relatively new form of play that can be described as a combination of adult forms of creative imagination (art, science, etc.), which require extensive real life experience, and children's forms of creative imagination (play), which require the embodiment of ideas and emotions in the material world. In playworlds, adults and children (or teenagers or seniors) enter into a common fantasy that is designed to support the development of both adults and children (or teenagers or seniors). The PWCR understands playworlds and the study of playworlds as ways of being. In this paper we present unique, individual playworlds that we truly love from the perspective of researchers, artists, teachers, children, administrators, and imaginary characters, who participate in playworlds. We use a master fiction writer's words on the love of literature to frame our discussion of playworlds, focusing on truth, time, human magic, infinite possibilities, fun, and the enriching and intensifying (and so, creating) of the real in playworlds in Japan, Finland, Sweden and the US.Peer reviewe
Warm water treatment increased mortality risk in salmon
Thermal treatment is a controversial method to control sea lice in the Atlantic salmon farming industry. This study aimed to complement the growing evidence base to document the impact of thermal treatments on salmon welfare, behaviour, physiology and health. Here, fish were treated two times (four weeks apart) for 30 s in either 27, 30, or 33 °C warm water, and parameters were compared to a procedural control (exposed to their holding temperature of 14 °C) or a negative control (where no treatments were applied). The fish had a clear behavioural response to the warm water, despite low difference between treatment and holding temperature (Δt = 13, 16 or 19 °C). Eye damages were more prevalent in the warm water treated groups than in the controls. Little difference was recorded between treatment groups in their growth and condition factor, blood plasma values, organ health, and long-term coping ability. There was, however, a significant increase in mortality as a function of temperature after the first treatment (14 °C: 6.5%, 27 °C: 5.3%, 30 °C: 12.4% and 33 °C: 18.9% mortality). The first treatment was performed only two weeks after the fish had been tagged and moved into the experimental holding tanks, while the fish had been allowed to recover for four weeks without any handling before the second treatment. The group of fish that were not subjected to any treatments (the negative control) had no mortality throughout the entire experimental period.publishedVersio
The hepatitis B x antigen anti-apoptotic effector URG7 is localized to the endoplasmic reticulum membrane
Hepatitis B x antigen up-regulates the liver expression of URG7 that contributes to sustain chronic
virus infection and to increase the risk for hepatocellular carcinoma by its anti-apoptotic activity.
We have investigated the subcellular localization of URG7 expressed in HepG2 cells and determined
its membrane topology by glycosylation mapping in vitro. The results demonstrate that URG7 is
N-glycosylated and located to the endoplasmic reticulum membrane with an Nlumen–Ccytosol orientation.
The results imply that the anti-apoptotic effect of URG7 could arise from the C-terminal
cytosolic tail binding a pro-apoptotic signaling factor and retaining it to the endoplasmic reticulum
membrane
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