Production Scheduling Requirements to Smart Manufacturing

The production scheduling has attracted a lot of researchers for many years, however most of the approaches are not targeted to deal with real manufacturing environments, and those that are, are very particular for the case study. It is crucial to consider important features related with the factories, such as products and machines characteristics and unexpected disturbances, but also information such as when the parts arrive to the factory and when should be delivered. So, the purpose of this paper is to identify some important characteristics that have been considered independently in a lot of studies and that should be considered together to develop a generic scheduling framework to be used in a real manufacturing environment.authorsversionpublishe

What causes hidradenitis suppurativa? - 15 years after

The 14 authors of the first review article on hidradenitis suppurativa (HS) pathogenesis published 2008 in EXPERIMENTAL DERMATOLOGY cumulating from the 1st International Hidradenitis Suppurativa Research Symposium held March 30?April 2, 2006 in Dessau, Germany with 33 participants were prophetic when they wrote "Hopefully, this heralds a welcome new tradition: to get to the molecular heart of HS pathogenesis, which can only be achieved by a renaissance of solid basic HS research, as the key to developing more effective HS therapy." (Kurzen et al. What causes hidradenitis suppurativa? Exp Dermatol 2008;17:455). Fifteen years later, there is no doubt that the desired renaissance of solid basic HS research is progressing with rapid steps and that HS has developed deep roots among inflammatory diseases in Dermatology and beyond, recognized as ?the only inflammatory skin disease than can be healed?. This anniversary article of 43 research-performing authors from all around the globe in the official journal of the European Hidradenitis Suppurativa Foundation e.V. (EHSF e.V.) and the Hidradenitis Suppurativa Foundation, Inc (HSF USA) summarizes the evidence of the intense HS clinical and experimental research during the last 15 years in all aspects of the disease and provides information of the developments to come in the near future

What causes hidradenitis suppurativa ?—15 years after

The 14 authors of the first review article on hidradenitis suppurativa (HS) pathogenesis published 2008 in EXPERIMENTAL DERMATOLOGY cumulating from the 1st International Hidradenitis Suppurativa Research Symposium held March 30–April 2, 2006 in Dessau, Germany with 33 participants were prophetic when they wrote “Hopefully, this heralds a welcome new tradition: to get to the molecular heart of HS pathogenesis, which can only be achieved by a renaissance of solid basic HS research, as the key to developing more effective HS therapy.” (Kurzen et al. What causes hidradenitis suppurativa? Exp Dermatol 2008;17:455). Fifteen years later, th

[B]MFI membrane: Synthesis, physico-chemical properties and catalytic behavior in the double-bond isomerization of 1-butene

An MFI type borosilicate, [B]MFI (Si/B=56), membrane was synthesized on the external surface of tubular -alumina support. The structure, morphology and acidity of the synthesized membrane were characterized by X-ray diffraction, SEM and FT-IR spectroscopy. A flow-through membrane reactor was constructed and the simultaneous catalytic and separation selectivity of the membrane was tested in the double-bond isomerization of 1-butene in the temperature range of 120-250°C and at 1-butene partial pressure of 18 and 50 kPa. No product of skeletal isomerization was formed under these conditions. The catalytic selectivity is attributed to the low acid strength of the Brønsted sites generated by the framework boron. Equilibrium trans/cis-2-butenes ratio was obtained in the retentate stream (1.4-1.5), whereas, that ratio at the permeate stream was up to ~2.2 at 250 oC. The high trans/cis ratio was attributed to the permeation selectivity of the MFI membrane for trans-2-butene